Works by Mirsalis, Jon

Results: 31

Micronucleated erythrocyte frequency in peripheral blood of B6C3F1 mice from short-term, prechronic, and chronic studies of the NTP carcinogenesis bioassay program.

Published in:

Environmental & Molecular Mutagenesis, 2000, v. 36, n. 3, p. 163, doi. 10.1002/1098-2280(2000)36:3<163::AID-EM1>3.0.CO;2-P

By:

Witt, Kristine L.;
Knapton, Alan;
Wehr, Carol M.;
Hook, Graham J.;
Mirsalis, Jon;
Shelby, Michael D.;
MacGregor, James T.

Publication type:

Article

In vivo transgenic mutation assays.

Published in:

Environmental & Molecular Mutagenesis, 2000, v. 35, n. 3, p. 253, doi. 10.1002/(SICI)1098-2280(2000)35:3<253::AID-EM11>3.0.CO;2-J

By:

Heddle, John A.;
Dean, Stephen;
Nohmi, Takehiko;
Boerrigter, Michaël;
Casciano, Daniel;
Douglas, George R.;
Glickman, Barry W.;
Gorelick, Nancy J.;
Mirsalis, Jon C.;
Martus, Hans-Jörg;
Skopek, Thomas R.;
Thybaud, Veronique;
Tindall, Kenneth R.;
Yajima, Nobuhiro

Publication type:

Article

Mutational spectrum of dimethylnitrosamine in the liver of 3- and 6-week-old lacI transgenic mice.

Published in:

Environmental & Molecular Mutagenesis, 1999, v. 34, n. 2/3, p. 80, doi. 10.1002/(SICI)1098-2280(1999)34:2/3<80::AID-EM4>3.0.CO;2-4

By:

de Boer, Johan G.;
Mirsalis, Jon C.;
Glickman, Barry W.

Publication type:

Article

Evaluation of positive controls for the in vitro unscheduled DNA synthesis assay using hepatocytes from induced (Aroclor 1254) and uninduced male cynomolgus monkey.

Published in:

Environmental & Molecular Mutagenesis, 1997, v. 30, n. 3, p. 354, doi. 10.1002/(SICI)1098-2280(1997)30:3<354::AID-EM15>3.0.CO;2-C

By:

Hamilton, Carol M.;
Dabbs, Jack E.;
Cunningham, Glenn D.;
Vernetti, Lawrence A.;
Mirsalis, Jon C.;
Snyder, Ronald D.

Publication type:

Article

Prospects for safety testing: A strategy for the application of transgenic rodent mutagenesis assays.

Published in:

Environmental & Molecular Mutagenesis, 1996, v. 28, n. 4, p. 434, doi. 10.1002/(SICI)1098-2280(1996)28:4<434::AID-EM20>3.0.CO;2-F

By:

Gorelick, Nancy J.;
Mirsalis, Jon C.

Publication type:

Article

Mutational specificity: Spectrum of mutations in kidney, stomach, and liver from lacl transgenic mice recovered after treatment with tris(2,3-dibromopropyl)phosphate.

Published in:

Environmental & Molecular Mutagenesis, 1996, v. 28, n. 4, p. 418, doi. 10.1002/(SICI)1098-2280(1996)28:4<418::AID-EM17>3.0.CO;2-I

By:

de Boer, Johan G.;
Mirsalis, Jon C.;
Provost, G. Scott;
Tindall, Kenneth R.;
Glickman, Barry W.

Publication type:

Article

Chromium (VI) at plausible drinking water concentrations is not genotoxic in the in vivo bone marrow micronucleus or liver unscheduled DNA synthesis assays.

Published in:

Environmental & Molecular Mutagenesis, 1996, v. 28, n. 1, p. 60, doi. 10.1002/(SICI)1098-2280(1996)28:1<60::AID-EM9>3.0.CO;2-I

By:

Mirsalis, Jon C.;
Hamilton, Carol M.;
O'Loughlin, Kathleen G.;
Paustenbach, Dennis J.;
Kerger, Brent D.;
Patierno, Steven

Publication type:

Article

Letter to the editor.

Published in:

Environmental & Molecular Mutagenesis, 1993, v. 22, n. 1, p. 59, doi. 10.1002/em.2850220110

By:

Mirsalis, Jon

Publication type:

Article

Evaluation of the potential of riddelliine to induce unscheduled DNA synthesis, S-phase synthesis, or micronuclei following in vivo treatment with multiple doses.

Published in:

Environmental & Molecular Mutagenesis, 1993, v. 21, n. 3, p. 265, doi. 10.1002/em.2850210310

By:

Mirsalis, Jon C.;
Steinmetz, Karen L.;
Blazak, William F.;
Spalding, Judson W.

Publication type:

Article

Measurement of unscheduled DNA synthesis and S-phase synthesis in rodent hepatocytes following in vivo treatment: Testing of 24 compounds.

Published in:

Environmental & Molecular Mutagenesis, 1989, v. 14, n. 3, p. 155, doi. 10.1002/em.2850140305

By:

Mirsalis, Jon C.;
Tyson, C. Kim;
Steinmetz, Karen L.;
Loh, Erica K.;
Hamilton, Carol M.;
Bakke, James P.;
Spalding, Judson W.

Publication type:

Article

Pyridine Does Not Induce Unscheduled DNA Synthesis (UDS) in Hepatocytes of Male B6C3F1 Mice Treated in Vivo.

Published in:

Journal of Applied Toxicology, 2000, v. 20, n. 5, p. 389, doi. 10.1002/1099-1263(200009/10)20:5<389::AID-JAT702>3.0.CO;2-O

By:

MacGregor, Judith A.;
Hamilton, Carol M.;
Kubicek, James E.;
Mirsalis, Jon C.

Publication type:

Article

3D Spheroids of Human Primary Urine-Derived Stem Cells in the Assessment of Drug-Induced Mitochondrial Toxicity.

Published in:

Pharmaceutics, 2022, v. 14, n. 5, p. 1042, doi. 10.3390/pharmaceutics14051042

By:

Ding, Huifen;
Jambunathan, Kalyani;
Jiang, Guochun;
Margolis, David M.;
Leng, Iris;
Ihnat, Michael;
Ma, Jian-Xing;
Mirsalis, Jon;
Zhang, Yuanyuan

Publication type:

Article

Correction to: Enhancement of sensitivity and quantification quality in the LC–MS/MS measurement of large biomolecules with sum of MRM (SMRM).

Published in:

2022

By:

Tang, Liang;
Swezey, Robert R.;
Green, Carol E.;
Mirsalis, Jon C.

Publication type:

Correction Notice

Enhancement of sensitivity and quantification quality in the LC–MS/MS measurement of large biomolecules with sum of MRM (SMRM).

Published in:

Analytical & Bioanalytical Chemistry, 2022, v. 414, n. 5, p. 1933, doi. 10.1007/s00216-021-03829-z

By:

Tang, Liang;
Swezey, Robert R.;
Green, Carol E.;
Mirsalis, Jon C.

Publication type:

Article

Preclinical pharmacokinetic, toxicological and biomarker evaluation of SR16157, a novel dual-acting steroid sulfatase inhibitor and selective estrogen receptor modulator.

Published in:

Cancer Chemotherapy & Pharmacology, 2011, v. 67, n. 6, p. 1341, doi. 10.1007/s00280-010-1430-x

By:

Rausch, Linda;
Green, Carol;
Steinmetz, Karen;
LeValley, Sue;
Catz, Paul;
Zaveri, Nurulain;
Schweikart, Karen;
Tomaszewski, Joseph;
Mirsalis, Jon

Publication type:

Article

Toxicity of a quinocarmycin analog, DX-52-1, in rats and dogs in relation to clinical outcome.

Published in:

Cancer Chemotherapy & Pharmacology, 2003, v. 51, n. 3, p. 193, doi. 10.1007/s00280-002-0553-0

By:

Mirsalis, Jon C.;
Schindler-Horvat, Janice;
Hill, James R.;
Green, Carol E.;
Mitoma, Chozo;
Tomaszewski, Joseph E.;
Tyson, Charles A.;
Donohue, Susan J.

Publication type:

Article

Evaluation of Cardiac Toxicity Biomarkers in Rats from Different Laboratories.

Published in:

Toxicologic Pathology, 2016, v. 44, n. 8, p. 1072, doi. 10.1177/0192623316668276

By:

Kim, Kyuri;
Chini, Naseem;
Fairchild, David G.;
Engle, Steven K.;
Reagan, William J.;
Summers, Sandra D.;
Mirsalis, Jon C.

Publication type:

Article

Preclinical Acute Toxicity Studies and Dosimetry Estimates of the Novel Sigma-1 Receptor Radiotracer, [18F]SFE.

Published in:

Molecular Imaging & Biology, 2006, v. 8, n. 5, p. 284, doi. 10.1007/s11307-006-0056-1

By:

Rikki Waterhouse;
Jun Zhao;
Michael Stabin;
Hanna Ng;
Janice Schindler-Horvat;
Raymond Chang;
Jon Mirsalis

Publication type:

Article

Evaluation of mutant frequencies of chemically induced tumors and normal tissues in ?/cII transgenic mice.

Published in:

Environmental & Molecular Mutagenesis, 2005, v. 45, n. 1, p. 17

By:

Jon C. Mirsalis;
Julie A. Shimon;
Alphonso Johnson;
David Fairchild;
Nathan Kanazawa;
Tung Nguyen;
Johan de Boer;
Barry Glickman;
Richard A. Winegar

Publication type:

Article

Genotoxicity and toxicity of the potential cancer-preventive agent polyphenon E.

Published in:

Environmental & Molecular Mutagenesis, 2003, v. 41, n. 1, p. 43, doi. 10.1002/em.10129

By:

Chang, Polly Y.;
Mirsalis, Jon;
Riccio, Edward S.;
Bakke, James P.;
Lee, Pamela S.;
Shimon, Julie;
Phillips, Sandra;
Fairchild, David;
Hara, Yukihiko;
Crowell, James A.

Publication type:

Article

Genetic toxicology testing of the antimalarial drugs chloroquine and a new analog, AQ-13.

Published in:

Environmental & Molecular Mutagenesis, 2001, v. 38, n. 1, p. 69, doi. 10.1002/em.1052

By:

Riccio, Edward S.;
Lee, Pamela S.;
Winegar, Richard A.;
Krogstad, Donald J.;
De, Dibyendu;
Mirsalis, Jon C.

Publication type:

Article

Biodistribution, toxicity and radiation dosimetry studies of the serotonin transporter radioligand 4-[18F]-ADAM in rats and monkeys.

Published in:

European Journal of Nuclear Medicine & Molecular Imaging, 2010, v. 37, n. 3, p. 545, doi. 10.1007/s00259-009-1281-z

By:

Ya-Yao Huang;
Kuo-Hsing Ma;
Ta-Wei Tseng;
Ta-Kai Chou;
Hanna Ng;
Mirsalis, Jon;
Ying-Kai Fu;
Tieh-Chi Chu;
Wen-Sheng Huang;
Chyng-Yann Shiue

Publication type:

Article

In Vivo Activity of Amodiaquine against Ebola Virus Infection.

Published in:

Scientific Reports, 2019, v. 9, n. 1, p. 1, doi. 10.1038/s41598-019-56481-0

By:

DeWald, Lisa Evans;
Johnson, Joshua C.;
Gerhardt, Dawn M.;
Torzewski, Lisa M.;
Postnikova, Elena;
Honko, Anna N.;
Janosko, Krisztina;
Huzella, Louis;
Dowling, William E.;
Eakin, Ann E.;
Osborn, Blaire L.;
Gahagen, Janet;
Tang, Liang;
Green, Carol E.;
Mirsalis, Jon C.;
Holbrook, Michael R.;
Jahrling, Peter B.;
Dyall, Julie;
Hensley, Lisa E.

Publication type:

Article

Vaccination with a recombinant vaccinia vaccine containing the B7-1 co-stimulatory molecule causes no significant toxicity and enhances T cell-mediated cytotoxicity.

Published in:

International Journal of Cancer, 2000, v. 85, n. 4, p. 508, doi. 10.1002/(SICI)1097-0215(20000215)85:4<508::AID-IJC11>3.0.CO;2-D

By:

Freund, Yvonne R.;
Mirsalis, Jon C.;
Fairchild, David G.;
Brune, Joyce;
Hokama, Leslie A.;
Schindler-Horvat, Janice;
Tomaszewski, Joseph E.;
Hodge, James W.;
Schlom, Jeffrey;
Kantor, Judy A.;
Tyson, Charles A.;
Donohue, Susan J.

Publication type:

Article

Gene Expression Analysis Reveals New Possible Mechanisms of Vancomycin-Induced Nephrotoxicity and Identifies Gene Markers Candidates.

Published in:

Toxicological Sciences, 2009, v. 107, n. 1, p. 258, doi. 10.1093/toxsci/kfn203

By:

Christine Dieterich;
Angela Puey;
Sylvia Lyn;
Robert Swezey;
Anna Furimsky;
David Fairchild;
Jon C. Mirsalis;
Hanna H. Ng

Publication type:

Article

Nonprofit organizations and pharmaceutical research and development.

Published in:

Drug Development Research, 2009, v. 70, n. 7, p. 461, doi. 10.1002/ddr.20326

By:

Moos, Walter H.;
Mirsalis, Jon C.

Publication type:

Article

In Vitro and In Vivo Activity of Amiodarone Against Ebola Virus.

Published in:

2018

By:

Dyall, Julie;
Johnson, Joshua C;
Hart, Brit J;
Postnikova, Elena;
Cong, Yu;
Zhou, Huanying;
Gerhardt, Dawn M;
Michelotti, Julia;
Honko, Anna N;
Kern, Steven;
DeWald, Lisa Evans;
O'Loughlin, Kathleen G;
Green, Carol E;
Mirsalis, Jon C;
Bennett, Richard S;
Olinger, Gene G Jr;
Jahrling, Peter B;
Hensley, Lisa E

Publication type:

journal article

Selecting an anti-malarial clinical candidate from two potent dihydroisoquinolones.

Published in:

Malaria Journal, 2021, v. 20, n. 1, p. 1, doi. 10.1186/s12936-021-03617-1

By:

Chen, Yizhe;
Zhu, Fangyi;
Hammill, Jared;
Holbrook, Gloria;
Yang, Lei;
Freeman, Burgess;
White, Karen L.;
Shackleford, David M.;
O'Loughlin, Kathleen G.;
Charman, Susan A.;
Mirsalis, Jon C.;
Guy, R. Kiplin

Publication type:

Article

New Candidate Biomarkers in the Female Genital Tract to Evaluate Microbicide Toxicity.

Published in:

PLoS ONE, 2014, v. 9, n. 10, p. 1, doi. 10.1371/journal.pone.0110980

By:

Fields, Scott;
Song, Benben;
Rasoul, Bareza;
Fong, Julie;
Works, Melissa G.;
Shew, Kenneth;
Yiu, Ying;
Mirsalis, Jon;
D'Andrea, Annalisa

Publication type:

Article

Formulation, Stability, Pharmacokinetic, and Modeling Studies for Tests of Synergistic Combinations of Orally Available Approved Drugs against Ebola Virus In Vivo.

Published in:

Microorganisms, 2021, v. 9, n. 3, p. 566, doi. 10.3390/microorganisms9030566

By:

Finch, Courtney L.;
Dyall, Julie;
Xu, Shuang;
Nelson, Elizabeth A.;
Postnikova, Elena;
Liang, Janie Y.;
Zhou, Huanying;
DeWald, Lisa Evans;
Thomas, Craig J.;
Wang, Amy;
Xu, Xin;
Hughes, Emma;
Morris, Patrick J.;
Mirsalis, Jon C.;
Nguyen, Linh H.;
Arolfo, Maria P.;
Koci, Bryan;
Holbrook, Michael R.;
Hensley, Lisa E.;
Jahrling, Peter B.

Publication type:

Article

Transgenic animal models for measuring mutations in vivo

Published in:

Critical Reviews in Toxicology, 1994, v. 24, n. 3, p. 255, doi. 10.3109/10408449409021608

By:

Mirsalis, Jon C.;
Monforte, Joseph A.;
Winegar, Richard A.

Publication type:

Article

Works by Mirsalis, Jon

Micronucleated erythrocyte frequency in peripheral blood of B6C3F<sub>1</sub> mice from short-term, prechronic, and chronic studies of the NTP carcinogenesis bioassay program.

In vivo transgenic mutation assays.

Mutational spectrum of dimethylnitrosamine in the liver of 3- and 6-week-old lacI transgenic mice.

Evaluation of positive controls for the in vitro unscheduled DNA synthesis assay using hepatocytes from induced (Aroclor 1254) and uninduced male cynomolgus monkey.

Prospects for safety testing: A strategy for the application of transgenic rodent mutagenesis assays.

Mutational specificity: Spectrum of mutations in kidney, stomach, and liver from lacl transgenic mice recovered after treatment with tris(2,3-dibromopropyl)phosphate.

Chromium (VI) at plausible drinking water concentrations is not genotoxic in the in vivo bone marrow micronucleus or liver unscheduled DNA synthesis assays.

Letter to the editor.

Evaluation of the potential of riddelliine to induce unscheduled DNA synthesis, S-phase synthesis, or micronuclei following in vivo treatment with multiple doses.

Measurement of unscheduled DNA synthesis and S-phase synthesis in rodent hepatocytes following in vivo treatment: Testing of 24 compounds.

Pyridine Does Not Induce Unscheduled DNA Synthesis (UDS) in Hepatocytes of Male B6C3F1 Mice Treated in Vivo.

3D Spheroids of Human Primary Urine-Derived Stem Cells in the Assessment of Drug-Induced Mitochondrial Toxicity.

Correction to: Enhancement of sensitivity and quantification quality in the LC–MS/MS measurement of large biomolecules with sum of MRM (SMRM).

Enhancement of sensitivity and quantification quality in the LC–MS/MS measurement of large biomolecules with sum of MRM (SMRM).

Preclinical pharmacokinetic, toxicological and biomarker evaluation of SR16157, a novel dual-acting steroid sulfatase inhibitor and selective estrogen receptor modulator.

Toxicity of a quinocarmycin analog, DX-52-1, in rats and dogs in relation to clinical outcome.

Evaluation of Cardiac Toxicity Biomarkers in Rats from Different Laboratories.

Preclinical Acute Toxicity Studies and Dosimetry Estimates of the Novel Sigma-1 Receptor Radiotracer, [<sup>18</sup>F]SFE.

Evaluation of mutant frequencies of chemically induced tumors and normal tissues in ?/cII transgenic mice.

Genotoxicity and toxicity of the potential cancer-preventive agent polyphenon E.

Genetic toxicology testing of the antimalarial drugs chloroquine and a new analog, AQ-13.

Biodistribution, toxicity and radiation dosimetry studies of the serotonin transporter radioligand 4-[<sup>18</sup>F]-ADAM in rats and monkeys.

In Vivo Activity of Amodiaquine against Ebola Virus Infection.

Vaccination with a recombinant vaccinia vaccine containing the B7-1 co-stimulatory molecule causes no significant toxicity and enhances T cell-mediated cytotoxicity.

Gene Expression Analysis Reveals New Possible Mechanisms of Vancomycin-Induced Nephrotoxicity and Identifies Gene Markers Candidates.

Nonprofit organizations and pharmaceutical research and development.

In Vitro and In Vivo Activity of Amiodarone Against Ebola Virus.

Selecting an anti-malarial clinical candidate from two potent dihydroisoquinolones.

New Candidate Biomarkers in the Female Genital Tract to Evaluate Microbicide Toxicity.

Formulation, Stability, Pharmacokinetic, and Modeling Studies for Tests of Synergistic Combinations of Orally Available Approved Drugs against Ebola Virus In Vivo.

Transgenic animal models for measuring mutations in vivo