Works by Mirochnick, Mark

Results: 45

Pharmacokinetic Enhancement of HIV Antiretroviral Therapy During Pregnancy.

Published in:

Journal of Clinical Pharmacology, 2020, v. 60, n. 12, p. 1537, doi. 10.1002/jcph.1714

By:

Salama, Engie;
Eke, Ahizechukwu C.;
Best, Brookie M.;
Mirochnick, Mark;
Momper, Jeremiah D.

Publication type:

Article

Physiologically Based Pharmacokinetic Models to Predict Maternal Pharmacokinetics and Fetal Exposure to Emtricitabine and Acyclovir.

Published in:

Journal of Clinical Pharmacology, 2020, v. 60, n. 2, p. 240, doi. 10.1002/jcph.1515

By:

Liu, Xiaomei I.;
Momper, Jeremiah D.;
Rakhmanina, Natella;
den Anker, John N.;
Green, Dionna J.;
Burckart, Gilbert J.;
Best, Brookie M.;
Mirochnick, Mark;
Capparelli, Edmund V.;
Dallmann, André

Publication type:

Article

Cobicistat as a Pharmacoenhancer in Pregnancy and Postpartum: Progress to Date and Next Steps.

Published in:

Journal of Clinical Pharmacology, 2019, v. 59, n. 6, p. 779, doi. 10.1002/jcph.1397

By:

Eke, Ahizechukwu C.;
Mirochnick, Mark H.

Publication type:

Article

Pharmacokinetics of Increased Nelfinavir Plasma Concentrations in Women During Pregnancy and Postpartum.

Published in:

Journal of Clinical Pharmacology, 2019, v. 59, n. 3, p. 386, doi. 10.1002/jcph.1331

By:

Eke, Ahizechukwu C.;
McCormack, Shelley A.;
Best, Brookie M.;
Stek, Alice M.;
Wang, Jiajia;
Kreitchmann, Regis;
Shapiro, David;
Smith, Elizabeth;
Mofenson, Lynne M.;
Capparelli, Edmund V.;
Mirochnick, Mark

Publication type:

Article

Evaluating darunavir/ritonavir dosing regimens for HIV-positive pregnant women using semi-mechanistic pharmacokinetic modelling.

Published in:

2019

By:

Schalkwijk, Stein;
Heine, Rob ter;
Colbers, Angela;
Capparelli, Edmund;
Best, Brookie M;
Cressey, Tim R;
Greupink, Rick;
Russel, Frans G M;
Moltó, José;
Mirochnick, Mark;
Karlsson, Mats O;
Burger, David M;
Ter Heine, Rob

Publication type:

journal article

Impact of body weight and missed doses on lopinavir concentrations with standard and increased lopinavir/ritonavir doses during late pregnancy.

Published in:

2015

By:

Cressey, Tim R;
Urien, Saik;
Capparelli, Edmund V;
Best, Brookie M;
Buranabanjasatean, Sudanee;
Limtrakul, Aram;
Rawangban, Boonsong;
Sabsanong, Prapan;
Treluyer, Jean-Marc;
Jourdain, Gonzague;
Stek, Alice;
Lallemant, Marc;
Mirochnick, Mark

Publication type:

journal article

Physiologically‐based pharmacokinetic modeling of remdesivir and its metabolites in pregnant women with COVID‐19.

Published in:

CPT: Pharmacometrics & Systems Pharmacology, 2023, v. 12, n. 2, p. 148, doi. 10.1002/psp4.12900

By:

Liu, Xiaomei I.;
Dallmann, André;
Brooks, Kristina;
Best, Brookie M.;
Clarke, Diana F.;
Mirochnick, Mark;
van den Anker, John N.;
Capparelli, Edmund V.;
Momper, Jeremiah D.

Publication type:

Article

Maternal–Neonatal Raltegravir Population Pharmacokinetics Modeling: Implications for Initial Neonatal Dosing.

Published in:

CPT: Pharmacometrics & Systems Pharmacology, 2019, v. 8, n. 9, p. 643, doi. 10.1002/psp4.12443

By:

Lommerse, Jos;
Clarke, Diana;
Kerbusch, Thomas;
Merdjan, Henri;
Witjes, Han;
Teppler, Hedy;
Mirochnick, Mark;
Acosta, Edward P.;
Wenning, Larissa;
Nachman, Sharon;
Chain, Anne

Publication type:

Article

Etravirine Pharmacokinetics in HIV-Infected Pregnant Women.

Published in:

Frontiers in Pharmacology, 2016, p. 1, doi. 10.3389/fphar.2016.00239

By:

Mulligan, Nikki;
Schalkwijk, Stein;
Best, Brookie M.;
Colbers, Angela;
Wang, Jiajia;
Capparelli, Edmund V.;
Moltó, José;
Stek, Alice M.;
Taylor, Graham;
Smith, Elizabeth;
Tenorio, Carmen Hidalgo;
Chakhtoura, Nahida;
van Kasteren, Marjo;
Fletcher, Courtney V.;
Mirochnick, Mark;
Burger, David

Publication type:

Article

Blood Pressure in Children Exposed Prenatally to Cocaine.

Published in:

Clinical Pediatrics, 1998, v. 37, n. 11, p. 659, doi. 10.1177/000992289803701103

By:

Needlman, Robert;
Frank, Deborah A.;
Cabral, Howard;
Mirochnick, Mark;
Kwon, Christopher;
Zuckerman, Barry

Publication type:

Article

Pharmacokinetics of antiretrovirals in pregnant women.

Published in:

2004

By:

Mirochnick, Mark;
Capparelli, Edmund

Publication type:

journal article

Nevirapine.

Published in:

Clinical Pharmacokinetics, 2000, v. 39, n. 4, p. 281, doi. 10.2165/00003088-200039040-00004

By:

Mirochnick, Mark;
Clarke, Diana F.;
Dorenbaum, Alejandro

Publication type:

Article

Importance of Prospective Studies in Pregnant and Breastfeeding Women Living With Human Immunodeficiency Virus.

Published in:

Clinical Infectious Diseases, 2019, v. 69, n. 7, p. 1254, doi. 10.1093/cid/ciz121

By:

Colbers, Angela;
Mirochnick, Mark;
Schalkwijk, Stein;
Penazzato, Martina;
Townsend, Claire;
Burger, David

Publication type:

Article

Toward Earlier Inclusion of Pregnant and Postpartum Women in Tuberculosis Drug Trials: Consensus Statements From an International Expert Panel.

Published in:

Clinical Infectious Diseases, 2016, v. 62, n. 6, p. 761, doi. 10.1093/cid/civ991

By:

Heather, D.;
Gupta, Amita;
Hernandez-Diaz, Sonia;
Jean-Philippe, Patrick;
Spiegel, Hans;
Lyerly, Anne D.;
Mirochnick, Mark;
Mofenson, Lynne M.;
Montepiedra, Grace;
Sahin, Leyla;
Savic, Radojka;
Swaminathan, Soumya;
Watts;
Mathad, Jyoti S.;
White, Amina;
Abdel-Rahman, Susan M.;
Albano, Jessica D.;
Botgros, Radu;
Brown, Vikki;
Browning, Renee S.

Publication type:

Article

Maraviroc Pharmacokinetics in HIV-1-Infected Pregnant Women.

Published in:

Clinical Infectious Diseases, 2015, v. 61, n. 10, p. 1582, doi. 10.1093/cid/civ587

By:

Colbers, Angela;
Best, Brookie;
Schalkwijk, Stein;
Jiajia Wang;
Stek, Alice;
Tenorio, Carmen Hidalgo;
Hawkins, David;
Taylor, Graham;
Kreitchmann, Regis;
Burchett, Sandra;
Haberl, Annette;
Kabeya, Kabamba;
van Kasteren, Marjo;
Smith, Elizabeth;
Capparelli, Edmund;
Burger, David;
Mirochnick, Mark

Publication type:

Article

Designing Drug Trials: Considerations for Pregnant Women.

Published in:

Clinical Infectious Diseases, 2014, v. 59, n. suppl_7, p. S437, doi. 10.1093/cid/ciu709

By:

Sheffield, Jeanne S.;
Siegel, David;
Mirochnick, Mark;
Heine, R. Phillips;
Nguyen, Christine;
Bergman, Kimberly L.;
Savic, Rada M.;
Long, Jill;
Dooley, Kelly E.;
Nesin, Mirjana

Publication type:

Article

A Comparison of 3 Regimens to Prevent Nevirapine Resistance Mutations in HIV-Infected Pregnant Women Receiving a Single Intrapartum Dose of Nevirapine.

Published in:

Clinical Infectious Diseases, 2012, v. 54, n. 2, p. 285, doi. 10.1093/cid/cir798

By:

Dyke, Russell B. Van;
Ngo-Giang-Huong, Nicole;
Shapiro, David E.;
Frenkel, Lisa;
Britto, Paula;
Roongpisuthipong, Anuvat;
Beck, Ingrid A.;
Yuthavisuthi, Praparb;
Prommas, Sinart;
Puthanakit, Thanyawee;
Achalapong, Jullapong;
Chotivanich, Nantasak;
Rasri, Wirawan;
Cressey, Tim R.;
Maupin, Robert;
Mirochnick, Mark;
Jourdain, Gonzague

Publication type:

Article

The last and first frontier - emerging challenges for HIV treatment and prevention in the first week of life with emphasis on premature and low birth weight infants.

Published in:

Journal of the International AIDS Society, 2015, v. 18, p. n/a, doi. 10.7448/IAS.18.7.20271

By:

Cotton, Mark F;
Holgate, Sandi;
Nelson, Aurelie;
Rabie, Helena;
Wedderburn, Catherine;
Mirochnick, Mark

Publication type:

Article

The last and first frontier – emerging challenges for HIV treatment and prevention in the first week of life with emphasis on premature and low birth weight infants.

Published in:

Journal of the International AIDS Society, 2015, v. 18, n. Supp 6, p. 1, doi. 10.7448/IAS.18.7.20271

By:

Cotton, Mark F.;
Holgate, Sandi;
Nelson, Aurelie;
Rabie, Helena;
Wedderburn, Catherine;
Mirochnick, Mark

Publication type:

Article

Developmental Pharmacokinetic Changes of Lamivudine in Infants and Children.

Published in:

Journal of Clinical Pharmacology, 2012, v. 52, n. 12, p. 1824, doi. 10.1177/0091270011426563

By:

Tremoulet, Adriana H.;
Nikanjam, Mina;
Cressey, Tim R.;
Chokephaibulkit, Kulkanya;
McKinney, Ross;
Mirochnick, Mark;
Capparelli, Edmund V.

Publication type:

Article

Tenofovir alafenamide use in pregnant and lactating women living with HIV.

Published in:

Expert Opinion on Drug Metabolism & Toxicology, 2020, v. 16, n. 4, p. 333, doi. 10.1080/17425255.2020.1738384

By:

Eke, Ahizechukwu C.;
Brooks, Kristina M.;
Gebreyohannes, Rahel D.;
Sheffield, Jeanne S.;
Dooley, Kelly E.;
Mirochnick, Mark

Publication type:

Article

Ritonavir and cobicistat as pharmacokinetic enhancers in pregnant women.

Published in:

Expert Opinion on Drug Metabolism & Toxicology, 2019, v. 15, n. 7, p. 523, doi. 10.1080/17425255.2019.1628947

By:

Eke, Ahizechukwu C.;
Mirochnick, Mark

Publication type:

Article

Lamivudine dosing for preterm infants exposed to HIV: a population pharmacokinetic modelling and simulation study.

Published in:

Journal of Antimicrobial Chemotherapy (JAC), 2024, v. 79, n. 10, p. 2570, doi. 10.1093/jac/dkae259

By:

Bekker, Adrie;
Capparelli, Edmund V;
Mirochnick, Mark;
Clarke, Diana F;
Cotton, Mark F;
Shapiro, Roger;
McCarthy, Katie;
Moye, Jack;
Violari, Avy;
Chokephaibulkit, Kulkanya;
Abrams, Elaine;
Penazzato, Martina;
Ruel, Theodore D;
Cressey, Tim R

Publication type:

Article

Prediction of dolutegravir pharmacokinetics and dose optimization in neonates via physiologically based pharmacokinetic (PBPK) modelling.

Published in:

2020

By:

Bunglawala, Fazila;
Rajoli, Rajith K R;
Mirochnick, Mark;
Owen, Andrew;
Siccardi, Marco

Publication type:

journal article

Optimizing Pharmacology Studies in Pregnant and Lactating Women Using Lessons From HIV: A Consensus Statement.

Published in:

Clinical Pharmacology & Therapeutics, 2021, v. 110, n. 1, p. 36, doi. 10.1002/cpt.2048

By:

Eke, Ahizechukwu C.;
Olagunju, Adeniyi;
Momper, Jeremiah;
Penazzato, Martina;
Abrams, Elaine J.;
Best, Brookie M.;
Capparelli, Edmund V.;
Bekker, Adrie;
Belew, Yodit;
Kiser, Jennifer J.;
Struble, Kimberly;
Taylor, Graham;
Waitt, Catriona;
Mirochnick, Mark;
Cressey, Tim R.;
Colbers, Angela;
Abrams, Elaine;
Aldrovandi, Grace;
Best, Brookie;
Black, Roberta

Publication type:

Article

Population pharmacokinetics of dapsone in children with human immunodeficiency virus infection<sup>*</sup>.

Published in:

Clinical Pharmacology & Therapeutics, 2001, v. 70, n. 1, p. 24, doi. 10.1067/mcp.2001.115891

By:

Mirochnick, Mark;
Cooper, Ellen;
Capparelli, Edmund;
McIntosh, Ken;
Lindsey, Jane;
Xu, Jing;
Jacobus, David;
Mofenson, Lynne;
Bonagura, Vincent R.;
Nachman, Sharon;
Yogev, Ram;
Sullivan, John L.;
Spector, Stephen A.

Publication type:

Article

Pharmacokinetics of zidovudine in infants: A population analysis across studies<sup>*</sup>.

Published in:

Clinical Pharmacology & Therapeutics, 1999, v. 66, n. 1, p. 16, doi. 10.1016/S0009-9236(99)70049-4

By:

Mirochnick, Mark;
Capparelli, Edmund;
Connor, James

Publication type:

Article

Reduced indinavir exposure during pregnancy.

Published in:

British Journal of Clinical Pharmacology, 2013, v. 76, n. 3, p. 475, doi. 10.1111/bcp.12078

By:

Cressey, Tim R.;
Best, Brookie M.;
Achalapong, Jullapong;
Stek, Alice;
Wang, Jiajia;
Chotivanich, Nantasak;
Yuthavisuthi, Prapap;
Suriyachai, Pornnapa;
Prommas, Sinart;
Shapiro, David E.;
Watts, D. Heather;
Smith, Elizabeth;
Capparelli, Edmund;
Kreitchmann, Regis;
Mirochnick, Mark

Publication type:

Article

Two-Dose Intrapartum/Newborn Nevirapine and Standard Antiretroviral Therapy to Reduce Perinatal HIV Transmission: A Randomized Trial.

Published in:

JAMA: Journal of the American Medical Association, 2002, v. 288, n. 2, p. 189, doi. 10.1001/jama.288.2.189

By:

Dorenbaum, Alejandro;
Cunningham, Coleen K.;
Gelber, Richard D.;
Culnane, Mary;
Mofenson, Lynne;
Britto, Paula;
Rekacewicz, Claire;
Newell, Marie-Louise;
Delfraissy, Jean Francois;
Cunningham-Schrader, Bethann;
Mirochnick, Mark;
Sullivan, John L.

Publication type:

Article

Potential of Long-Acting Products to Transform the Treatment and Prevention of Human Immunodeficiency Virus (HIV) in Infants, Children, and Adolescents.

Published in:

Clinical Infectious Diseases, 2022, v. 75, p. S562, doi. 10.1093/cid/ciac754

By:

Abrams, Elaine J;
Capparelli, Edmund;
Ruel, Theodore;
Mirochnick, Mark

Publication type:

Article

Influence of NAT2 Genotype and Maturation on Isoniazid Exposure in Low-Birth-Weight and Preterm Infants With or Without Human Immunodeficiency Virus (HIV) Exposure.

Published in:

Clinical Infectious Diseases, 2022, v. 75, n. 6, p. 1037, doi. 10.1093/cid/ciac001

By:

Béranger, Agathe;
Bekker, Adrie;
Solans, Belén P;
Cotton, Mark F;
Mirochnick, Mark;
Violari, Avy;
Wang, Jiajia;
Cababasay, Mae;
Wiesner, Lubbe;
Browning, Renee;
Moye, Jack;
Capparelli, Edmund V;
Savic, Radojka M

Publication type:

Article

Antiretroviral Concentrations in Breast-Feeding Infants of Women in Botswana Receiving Antiretroviral Treatment.

Published in:

Journal of Infectious Diseases, 2005, v. 192, n. 5, p. 720, doi. 10.1086/432483

By:

Shapiro, Roger L.;
Holland, Diane T.;
Capparelli, Edmund;
Lockman, Shahin;
Thior, Ibou;
Wester, Carolyn;
Stevens, Lisa;
Peter, Trevor;
Essex, Max;
Connor, James D.;
Mirochnick, Mark

Publication type:

Article

Pharmacokinetics of Nevirapine in Human Immunodeficiency Virus Type 1-Infected Pregnant Women and Their Neonates.

Published in:

Journal of Infectious Diseases, 1998, v. 178, n. 2, p. 368, doi. 10.1086/515641

By:

Mirochnick, Mark;
Fenton, Terry;
Gagnier, Paul;
Pav, Joseph;
Gwynne, Meg;
Siminski, Sue;
Sperling, Rhoda S.;
Beckerman, Karen;
Jimenez, Eleanor;
Yogev, Ram;
Spector, Stephen A.;
Sullivan, John L.

Publication type:

Article

Antiretroviral Pharmacology in Pregnant Women and Their Newborns.

Published in:

Annals of the New York Academy of Sciences, 2000, v. 918, n. 1, p. 287, doi. 10.1111/j.1749-6632.2000.tb05498.x

By:

MIROCHNICK, MARK

Publication type:

Article

Praziquantel for the treatment of schistosomiasis during human pregnancy.

Published in:

Bulletin of the World Health Organization, 2018, v. 96, n. 1, p. 59, doi. 10.2471/BLT.17.198879

By:

Friedman, Jennifer F.;
Olveda, Remigio M.;
Mirochnick, Mark H.;
Bustinduy, Amaya L.;
Elliott, Alison M.

Publication type:

Article

Determination of Benznidazole in Human Dried Blood Spots by Liquid Chromatography--Mass Spectrometry to Monitor Adherence to Trypanosoma cruzi Infection Treatment in Infants and Children.

Published in:

American Journal of Tropical Medicine & Hygiene, 2019, v. 101, n. 1, p. 116, doi. 10.4269/ajtmh.18-0852

By:

Momper, Jeremiah D.;
Hanan, Nathan J.;
Rossi, Steven S.;
Mirochnick, Mark H.;
Cafferata, Maria Luisa;
Lavenia, Antonia;
Flores, Isolina;
Gibbons, Luz;
Ciganda, Alvaro;
Estani, Sergio Sosa;
Capparelli, Edmund V.;
Buekens, Pierre

Publication type:

Article

Lopinavir and tenofovir interaction observed in non‐pregnant adults altered during pregnancy.

Published in:

Journal of Clinical Pharmacy & Therapeutics, 2021, v. 46, n. 5, p. 1459, doi. 10.1111/jcpt.13477

By:

Mulligan, Nikki;
Salama, Engie;
Momper, Jeremiah D.;
Capparelli, Edmund V.;
Stek, Alice;
Chakhtoura, Nahida;
Mirochnick, Mark;
Best, Brookie M.

Publication type:

Article

Neonatal Necrotizing Enterocolitis With Intestinal Perforation in Extremely Premature Infants Receiving Early Indomethacin Treatment for Patent Ductus Arteriosus.

Published in:

Journal of Perinatology, 2002, v. 22, n. 7, p. 535, doi. 10.1038/sj.jp.7210795

By:

Fujii, Alan M;
Brown, Elizabeth;
Mirochnick, Mark;
O'Brien, Sharon;
Kaufman, Gary

Publication type:

Article

Prevention and treatment of HIV infection in neonates: evidence base for existing WHO dosing recommendations and implementation considerations.

Published in:

Expert Review of Clinical Pharmacology, 2018, v. 11, n. 1, p. 83, doi. 10.1080/17512433.2018.1393331

By:

Clarke, Diana F;
Penazzato, Martina;
Capparelli, Edmund;
Cressey, Tim R;
Siberry, George;
Sugandhi, Nandita;
Mirochnick, Mark

Publication type:

Article

Assessment of minority frequency pretreatment HIV drug-resistant variants in pregnant women and associations with virologic non-suppression at term.

Published in:

PLoS ONE, 2022, v. 17, n. 9, p. 1, doi. 10.1371/journal.pone.0275254

By:

Boyce, Ceejay L.;
Beck, Ingrid A.;
Styrchak, Sheila M.;
Hardy, Samantha R.;
Wallner, Jackson J.;
Milne, Ross S.;
Morrison, R. Leavitt;
Shapiro, David E.;
João, Esaú C.;
Mirochnick, Mark H.;
Frenkel, Lisa M.

Publication type:

Article

Pharmacokinetics and Safety of Levofloxacin for Treatment of Rifampicin-Resistant Tuberculosis During Pregnancy and the Postpartum Period: Results from IMPAACT P1026s.

Published in:

Clinical Pharmacokinetics, 2025, v. 64, n. 4, p. 619, doi. 10.1007/s40262-025-01498-0

By:

Hughes, Jennifer A.;
Pinilla, Mauricio;
Brooks, Kristina M.;
Eke, Ahizechukwu C.;
Stek, Alice;
Best, Brookie M.;
Mirochnick, Mark;
Browning, Renee;
Wiesner, Lubbe;
George, Kathleen;
Knowles, Kevin;
De Koker, Petra;
Ngocho, James S.;
Fairlie, Lee;
Chakhtoura, Nahida;
Hesseling, Anneke C.;
Decloedt, Eric;
Shapiro, David E.;
van Schalkwyk, Marije

Publication type:

Article

Prediction of Maternal and Fetal Pharmacokinetics of Dolutegravir and Raltegravir Using Physiologically Based Pharmacokinetic Modeling.

Published in:

Clinical Pharmacokinetics, 2020, v. 59, n. 11, p. 1433, doi. 10.1007/s40262-020-00897-9

By:

Liu, Xiaomei I.;
Momper, Jeremiah D.;
Rakhmanina, Natella Y.;
Green, Dionna J.;
Burckart, Gilbert J.;
Cressey, Tim R.;
Mirochnick, Mark;
Best, Brookie M.;
van den Anker, John N.;
Dallmann, André

Publication type:

Article

Innovative Approaches for Pharmacology Studies in Pregnant and Lactating Women: A Viewpoint and Lessons from HIV.

Published in:

Clinical Pharmacokinetics, 2020, v. 59, n. 10, p. 1185, doi. 10.1007/s40262-020-00915-w

By:

Eke, Ahizechukwu C.;
Olagunju, Adeniyi;
Best, Brookie M.;
Mirochnick, Mark;
Momper, Jeremiah D.;
Abrams, Elaine;
Penazzato, Martina;
Cressey, Tim R.;
Colbers, Angela

Publication type:

Article

A Mechanism-Based Population Pharmacokinetic Analysis Assessing the Feasibility of Efavirenz Dose Reduction to 400 mg in Pregnant Women.

Published in:

2018

By:

Schalkwijk, Stein;
ter Heine, Rob;
Colbers, Angela C.;
Huitema, Alwin D. R.;
Denti, Paolo;
Dooley, Kelly E.;
Capparelli, Edmund;
Best, Brookie M.;
Cressey, Tim R.;
Greupink, Rick;
Russel, Frans G. M.;
Mirochnick, Mark;
Burger, David M.

Publication type:

journal article

Nevirapine plasma concentrations in premature infants exposed to single-dose nevirapine for prevention of mother-tochild transmission of HIV-1.

Published in:

SAMJ: South African Medical Journal, 2011, v. 101, n. 9, p. 655

By:

Mugabo, Pierre;
Els, Ilse;
Smith, Johan;
Rabie, Helena;
Smith, Peter;
Mirochnick, Mark;
Steyn, Wilhelm;
Hall, David;
Madsen, Richard;
Cotton, Mark F.

Publication type:

Article