Works matching AU Minikel, Eric Vallabh

Results: 9

Analysis of non-human primate models for evaluating prion disease therapeutic efficacy.

Published in:

2022

By:

Mortberg, Meredith A.;
Minikel, Eric Vallabh;
Vallabh, Sonia M.

Publication type:

Literature Review

Disease stages and therapeutic hypotheses in two decades of neurodegenerative disease clinical trials.

Published in:

Scientific Reports, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41598-022-21820-1

By:

Mortberg, Meredith A.;
Vallabh, Sonia M.;
Minikel, Eric Vallabh

Publication type:

Article

Quantifying prion disease penetrance using large population control cohorts.

Published in:

Science Translational Medicine, 2016, v. 8, n. 322, p. 1, doi. 10.1126/scitranslmed.aad5169

By:

Minikel, Eric Vallabh;
Vallabh, Sonia M.;
Monkol Lek;
Estrada, Karol;
Samocha, Kaitlin E.;
Sathirapongsasuti, J. Fah;
McLean, Cory Y.;
Tung, Joyce Y.;
Yu, Linda P. C.;
Gambetti, Pierluigi;
Blevins, Janis;
Shulin Zhang;
Yvonne Cohen;
Wei Chen;
Masahito Yamada;
Tsuyoshi Hamaguchi;
Nobuo Sanjo;
Hidehiro Mizusawa;
Yosikazu Nakamura;
Tetsuyuki Kitamoto

Publication type:

Article

Human genetic evidence enriched for side effects of approved drugs.

Published in:

PLoS Genetics, 2025, v. 21, n. 3, p. 1, doi. 10.1371/journal.pgen.1011638

By:

Minikel, Eric Vallabh;
Nelson, Matthew R.

Publication type:

Article

Characterization of the Prion Protein Binding Properties of Antisense Oligonucleotides.

Published in:

Biomolecules (2218-273X), 2020, v. 10, n. 1, p. 1, doi. 10.3390/biom10010001

By:

Reidenbach, Andrew G.;
Minikel, Eric Vallabh;
Zhao, Hien T.;
Guzman, Stacy G.;
Leed, Alison J.;
Mesleh, Michael F.;
Kordasiewicz, Holly B.;
Schreiber, Stuart L.;
Vallabh, Sonia M.

Publication type:

Article

Cerebrospinal fluid and plasma biomarkers in individuals at risk for genetic prion disease.

Published in:

2020

By:

Vallabh, Sonia M.;
Minikel, Eric Vallabh;
Williams, Victoria J.;
Carlyle, Becky C.;
McManus, Alison J.;
Wennick, Chase D.;
Bolling, Anna;
Trombetta, Bianca A.;
Urick, David;
Nobuhara, Chloe K.;
Gerber, Jessica;
Duddy, Holly;
Lachmann, Ingolf;
Stehmann, Christiane;
Collins, Steven J.;
Blennow, Kaj;
Zetterberg, Henrik;
Arnold, Steven E.

Publication type:

journal article

A single-cell map of antisense oligonucleotide activity in the brain.

Published in:

Nucleic Acids Research, 2023, v. 51, n. 14, p. 7109, doi. 10.1093/nar/gkad371

By:

Mortberg, Meredith A;
Gentile, Juliana E;
Nadaf, Naeem M;
Vanderburg, Charles;
Simmons, Sean;
Dubinsky, Dan;
Slamin, Adam;
Maldonado, Salome;
Petersen, Caroline L;
Jones, Nichole;
Kordasiewicz, Holly B;
Zhao, Hien T;
Vallabh, Sonia M;
Minikel, Eric Vallabh

Publication type:

Article

Prion protein lowering is a disease-modifying therapy across prion disease stages, strains and endpoints.

Published in:

Nucleic Acids Research, 2020, v. 48, n. 19, p. 10615, doi. 10.1093/nar/gkaa616

By:

Minikel, Eric Vallabh;
Zhao, Hien T;
Le, Jason;
O'Moore, Jill;
Pitstick, Rose;
Graffam, Samantha;
Carlson, George A;
Kavanaugh, Michael P;
Kriz, Jasna;
Kim, Jae Beom;
Ma, Jiyan;
Wille, Holger;
Aiken, Judd;
McKenzie, Deborah;
Doh-ura, Katsumi;
Beck, Matthew;
O'Keefe, Rhonda;
Stathopoulos, Jacquelyn;
Caron, Tyler;
Schreiber, Stuart L

Publication type:

Article

Where have prions been all our lives?

Published in:

Brain: A Journal of Neurology, 2023, v. 146, n. 6, p. 2206, doi. 10.1093/brain/awad143

By:

Vallabh, Eric Minikel;
Vallabh, Sonia M

Publication type:

Article