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Golexanolone reduces glial activation in the striatum and improves non-motor and some motor alterations in a rat model of Parkinson's disease.
- Published in:
- Frontiers in Aging Neuroscience, 2024, p. 1, doi. 10.3389/fnagi.2024.1417938
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- Article
Neuroinflammation alters GABAergic neurotransmission in hyperammonemia and hepatic encephalopathy, leading to motor incoordination. Mechanisms and therapeutic implications.
- Published in:
- Frontiers in Pharmacology, 2024, p. 1, doi. 10.3389/fphar.2024.1358323
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- Article
Golexanolone improves fatigue, motor incoordination and gait and memory in rats with bile duct ligation.
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- Liver International, 2024, v. 44, n. 2, p. 433, doi. 10.1111/liv.15782
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- Article
Patients who died with steatohepatitis or liver cirrhosis show neuroinflammation and neuronal loss in hippocampus.
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- European Journal of Neurology, 2023, v. 30, n. 10, p. 3032, doi. 10.1111/ene.15935
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- Article
Golexanolone, a GABA<sub>A</sub> receptor modulating steroid antagonist, restores motor coordination and cognitive function in hyperammonemic rats by dual effects on peripheral inflammation and neuroinflammation.
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- CNS Neuroscience & Therapeutics, 2022, v. 28, n. 11, p. 1861, doi. 10.1111/cns.13926
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- Article
Rifaximin Improves Spatial Learning and Memory Impairment in Rats with Liver Damage-Associated Neuroinflammation.
- Published in:
- Biomedicines, 2022, v. 10, n. 6, p. 1263, doi. 10.3390/biomedicines10061263
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- Article