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Bithionol eliminates acute myeloid leukaemia stem-like cells by suppressing NF-κB signalling and inducing oxidative stress, leading to apoptosis and ferroptosis.
- Published in:
- Cell Death Discovery, 2024, v. 10, n. 1, p. 1, doi. 10.1038/s41420-024-02148-3
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- Publication type:
- Article
Differential TERT promoter methylation and response to 5-aza-2′-deoxycytidine in acute myeloid leukemia cell lines: TERT expression, telomerase activity, telomere length, and cell death.
- Published in:
- Genes, Chromosomes & Cancer, 2012, v. 51, n. 8, p. 768, doi. 10.1002/gcc.21962
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- Publication type:
- Article
A combined connectivity mapping and pharmacoepidemiology approach to identify existing medications with breast cancer causing or preventing properties.
- Published in:
- Pharmacoepidemiology & Drug Safety, 2018, v. 27, n. 1, p. 78, doi. 10.1002/pds.4345
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- Publication type:
- Article
Immunotherapy of myeloid leukaemia.
- Published in:
- Cancer Immunology, Immunotherapy, 2007, v. 56, n. 7, p. 943, doi. 10.1007/s00262-006-0267-y
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- Publication type:
- Article
Inter-Laboratory Evaluation of a Next-Generation Sequencing Panel for Acute Myeloid Leukemia.
- Published in:
- Molecular Diagnosis & Therapy, 2016, v. 20, n. 5, p. 457, doi. 10.1007/s40291-016-0222-3
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- Publication type:
- Article
The ruxolitinib effect: understanding how molecular pathogenesis and epigenetic dysregulation impact therapeutic efficacy in myeloproliferative neoplasms.
- Published in:
- 2018
- By:
- Publication type:
- journal article
Homozygous MHC Genotypes and Longevity.
- Published in:
- Human Heredity, 1994, v. 44, n. 5, p. 271, doi. 10.1159/000154229
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- Publication type:
- Article
Improving quality of life for people 65 and over living with dementia using a personalised memory game application.
- Published in:
- International Journal of Integrated Care (IJIC), 2022, v. 22, p. 1, doi. 10.5334/ijic.ICIC22168
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- Publication type:
- Article
An endogenously activated antiviral state restricts SARS-CoV-2 infection in differentiated primary airway epithelial cells.
- Published in:
- PLoS ONE, 2022, v. 17, n. 4, p. 1, doi. 10.1371/journal.pone.0266412
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- Publication type:
- Article
Combination Therapies Targeting Apoptosis in Paediatric AML: Understanding the Molecular Mechanisms of AML Treatments Using Phosphoproteomics.
- Published in:
- International Journal of Molecular Sciences, 2023, v. 24, n. 6, p. 5717, doi. 10.3390/ijms24065717
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- Publication type:
- Article
Survivin' Acute Myeloid Leukaemia—A Personalised Target for inv(16) Patients.
- Published in:
- International Journal of Molecular Sciences, 2021, v. 22, n. 19, p. 10482, doi. 10.3390/ijms221910482
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- Publication type:
- Article
Multiplex Screening for Interacting Compounds in Paediatric Acute Myeloid Leukaemia.
- Published in:
- International Journal of Molecular Sciences, 2021, v. 22, n. 18, p. 10163, doi. 10.3390/ijms221810163
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- Publication type:
- Article
Significance of NPM1 Gene Mutations in AML.
- Published in:
- International Journal of Molecular Sciences, 2021, v. 22, n. 18, p. 10040, doi. 10.3390/ijms221810040
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- Publication type:
- Article
The Impact of Epigenetic Modifications in Myeloid Malignancies.
- Published in:
- International Journal of Molecular Sciences, 2021, v. 22, n. 9, p. 5013, doi. 10.3390/ijms22095013
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- Publication type:
- Article
QUADrATiC: scalable gene expression connectivity mapping for repurposing FDA-approved therapeutics.
- Published in:
- BMC Bioinformatics, 2016, v. 17, p. 1, doi. 10.1186/s12859-016-1062-1
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- Publication type:
- Article
In Memoriam.
- Published in:
- Journal of Thermal Analysis & Calorimetry, 2005, v. 80, n. 3, p. 803, doi. 10.1007/s10973-005-0734-2
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- Publication type:
- Article
In memoriam Ákos Osvald Michael John Richardson BSc, PhD, FRSC, CChem.
- Published in:
- 2005
- By:
- Publication type:
- Obituary
Influence of the major histocompatibility complex on age at onset of chronic lymphoid leukaemia.
- Published in:
- International Journal of Cancer, 1996, v. 65, n. 2, p. 134, doi. 10.1002/(SICI)1097-0215(19960117)65:2<134::AID-IJC2>3.0.CO;2-#
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- Publication type:
- Article
P-056: HUWE1 orchestrates DNA Repair in response to Replicative Stress in Multiple Myeloma.
- Published in:
- Clinical Lymphoma, Myeloma & Leukemia, 2021, v. 21, p. S69, doi. 10.1016/S2152-2650(21)02190-X
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- Publication type:
- Article
P-054: TRIM33 loss in Multiple Myeloma is associated with defective DNA repair and sensitivity to PARP inhibition.
- Published in:
- Clinical Lymphoma, Myeloma & Leukemia, 2021, v. 21, p. S68, doi. 10.1016/S2152-2650(21)02188-1
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- Publication type:
- Article
Dysregulation of HUWE1 is associated with an increased mutational burden in Multiple Myeloma.
- Published in:
- Clinical Lymphoma, Myeloma & Leukemia, 2019, v. 19, p. e71, doi. 10.1016/j.clml.2019.09.112
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- Publication type:
- Article
Loss of TRIM33 in Multiple Myeloma correlates with increased genomic instability.
- Published in:
- Clinical Lymphoma, Myeloma & Leukemia, 2019, v. 19, p. e70, doi. 10.1016/j.clml.2019.09.111
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- Publication type:
- Article
An integrated meta-analysis approach to identifying medications with potential to alter breast cancer risk through connectivity mapping.
- Published in:
- BMC Bioinformatics, 2017, v. 18, p. 1, doi. 10.1186/s12859-017-1989-x
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- Publication type:
- Article
The Northern Ireland Biobank: A Cancer Focused Repository of Science.
- Published in:
- Open Journal of Bioresources, 2018, v. 5, n. 1, p. 1, doi. 10.5334/ojb.47
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- Publication type:
- Article
The Northern Ireland Biobank: A Cancer Focused Repository of Science.
- Published in:
- Open Journal of Bioresources, 2018, v. 5, p. 1, doi. 10.5334/ojb.47
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- Publication type:
- Article
Selective serotonin reuptake inhibitor use and breast cancer survival: a population-based cohort study.
- Published in:
- 2018
- By:
- Publication type:
- journal article
Assessment of the status and viability of a population of moose ( Alces alces) at its southern range limit in Ontario.
- Published in:
- Canadian Journal of Zoology, 2012, v. 90, n. 3, p. 422, doi. 10.1139/z2012-002
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- Publication type:
- Article
Altered methylation levels in elderly acute myeloid leukaemia patients compared to elderly well individuals.
- Published in:
- British Journal of Haematology, 2013, v. 161, n. 2, p. 294, doi. 10.1111/bjh.12221
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- Publication type:
- Article
Prognostic and therapeutic relevance of c- FLIP in acute myeloid leukaemia.
- Published in:
- British Journal of Haematology, 2013, v. 160, n. 2, p. 188, doi. 10.1111/bjh.12108
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- Publication type:
- Article
Elevated TRIB2 with NOTCH1 activation in paediatric/adult T- ALL.
- Published in:
- British Journal of Haematology, 2012, v. 158, n. 5, p. 626, doi. 10.1111/j.1365-2141.2012.09222.x
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- Publication type:
- Article
New prognostic markers, determined using gene expression analyses, reveal two distinct subtypes of chronic myelomonocytic leukaemia patients.
- Published in:
- British Journal of Haematology, 2012, v. 157, n. 3, p. 347, doi. 10.1111/j.1365-2141.2012.09069.x
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- Publication type:
- Article
Nuclear factor-κB as a potential therapeutic target for the novel cytotoxic agent LC-1 in acute myeloid leukaemia.
- Published in:
- British Journal of Haematology, 2008, v. 143, n. 5, p. 661, doi. 10.1111/j.1365-2141.2008.07392.x
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- Publication type:
- Article
An international standardization programme towards the application of gene expression profiling in routine leukaemia diagnostics: the Microarray Innovations in LEukemia study prephase.
- Published in:
- British Journal of Haematology, 2008, v. 142, n. 5, p. 802, doi. 10.1111/j.1365-2141.2008.07261.x
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- Publication type:
- Article
Heat shock protein 90 inhibition is cytotoxic to primary AML cells expressing mutant FLT3 and results in altered downstream signalling.
- Published in:
- British Journal of Haematology, 2008, v. 141, n. 4, p. 483, doi. 10.1111/j.1365-2141.2008.07053.x
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- Publication type:
- Article
SSX2IP expression in acute myeloid leukaemia: an association with mitotic spindle failure in t(8;21), and cell cycle in t(15;17) patients.
- Published in:
- 2008
- By:
- Publication type:
- Letter
Comparison of the survival implications of tumour-associated versus cancer-testis antigen expression in acute myeloid leukaemia.
- Published in:
- 2007
- By:
- Publication type:
- Letter
The tumour antigens RAGE-1 and MGEA6 are expressed more frequently in the less lineage restricted subgroups of presentation acute myeloid leukaemia.
- Published in:
- 2006
- By:
- Publication type:
- Letter
Rapid and sensitive detection of internal tandem duplication and activating loop mutations of FLT3.
- Published in:
- British Journal of Haematology, 2005, v. 130, n. 2, p. 203, doi. 10.1111/j.1365-2141.2005.05589.x
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- Publication type:
- Article
Post-diagnostic antipsychotic use and cancer mortality: a population based cohort study.
- Published in:
- 2020
- By:
- Publication type:
- journal article
Oncogenic roles of PRL-3 in FLT3- ITD induced acute myeloid leukaemia.
- Published in:
- EMBO Molecular Medicine, 2013, v. 5, n. 9, p. 1351, doi. 10.1002/emmm.201202183
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- Publication type:
- Article
Validation of Next Generation Sequencing Technologies in Comparison to Current Diagnostic Gold Standards for <i>BRAF</i>, <i>EGFR</i> and <i>KRAS</i> Mutational Analysis.
- Published in:
- PLoS ONE, 2013, v. 8, n. 7, p. 1, doi. 10.1371/journal.pone.0069604
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- Publication type:
- Article
Characterisation of Genome-Wide PLZF/RARA Target Genes.
- Published in:
- PLoS ONE, 2011, v. 6, n. 9, p. 1, doi. 10.1371/journal.pone.0024176
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- Publication type:
- Article
Entinostat Prevents Leukemia Maintenance in a Collaborating Oncogene-Dependent Model of Cytogenetically Normal Acute Myeloid Leukemia.
- Published in:
- Stem Cells, 2013, v. 31, n. 7, p. 1434, doi. 10.1002/stem.1398
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- Publication type:
- Article
Serum profiling identifies ibrutinib as a treatment option for young adults with B‐cell acute lymphoblastic leukaemia.
- Published in:
- British Journal of Haematology, 2020, v. 189, n. 3, p. 500, doi. 10.1111/bjh.16407
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- Publication type:
- Article
Compositional analysis gives insight into leukaemia cell lines expression profiles compared to those within patient sub‐groups.
- Published in:
- British Journal of Haematology, 2018, v. 181, n. 6, p. 847, doi. 10.1111/bjh.14711
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- Publication type:
- Article
Persistence of DNMT3A does not influence clinical outcome in acute myeloid leukaemia.
- Published in:
- 2016
- By:
- Publication type:
- Editorial
High and low, but not intermediate, PRAME expression levels are poor prognostic markers in myelodysplastic syndrome at disease presentation.
- Published in:
- British Journal of Haematology, 2013, v. 162, n. 2, p. 282, doi. 10.1111/bjh.12352
- By:
- Publication type:
- Article
Development of predictive methods for strain at the surface due to longwall coal mining.
- Published in:
- Mining Technology (2572-6668), 2018, v. 127, n. 2, p. 103, doi. 10.1080/14749009.2017.1386815
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- Publication type:
- Article
Identification of the Antigens Recognised by Colorectal Cancer Patients Using Sera from Patients Who Exhibit a Crohn's-like Lymphoid Reaction.
- Published in:
- Biomolecules (2218-273X), 2022, v. 12, n. 8, p. 1058, doi. 10.3390/biom12081058
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- Publication type:
- Article
Molecular pathogenesis of the myeloproliferative neoplasms.
- Published in:
- Journal of Hematology & Oncology, 2021, v. 14, p. 1, doi. 10.1186/s13045-021-01116-z
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- Publication type:
- Article