Works by Miller, Todd W.
Results: 64
Molecular and epigenetic profiles of BRCA1-like hormone-receptor-positive breast tumors identified with development and application of a copy-number-based classifier.
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- 2019
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- Publication type:
- journal article
Statistical determination of synergy based on Bliss definition of drugs independence.
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- PLoS ONE, 2019, v. 14, n. 11, p. 1, doi. 10.1371/journal.pone.0224137
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- Article
Integrated pan-cancer gene expression and drug sensitivity analysis reveals SLFN11 mRNA as a solid tumor biomarker predictive of sensitivity to DNA-damaging chemotherapy.
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- PLoS ONE, 2019, v. 14, n. 11, p. 1, doi. 10.1371/journal.pone.0224267
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- Article
Structure and autoregulation of the insulin-like growth factor 1 receptor kinase.
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- Nature Structural Biology, 2001, v. 8, n. 12, p. 1058, doi. 10.1038/nsb721
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- Article
Double trouble.
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- Nature Structural Biology, 2001, v. 8, n. 1, p. 16, doi. 10.1038/82986
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- Article
Auto-thiophosphorylation activity of Src tyrosine kinase.
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- BMC Biochemistry, 2016, v. 17, p. 1, doi. 10.1186/s12858-016-0071-z
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- Article
Molecular characterization of WDCP, a novel fusion partner for the anaplastic lymphoma tyrosine kinase ALK.
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- Biomedical Reports, 2015, v. 3, n. 1, p. 9, doi. 10.3892/br.2014.374
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- Article
Role of the Brk SH3 domain in substrate recognition.
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- Oncogene, 2004, v. 23, n. 12, p. 2216, doi. 10.1038/sj.onc.1207339
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- Article
Clinical potential of novel therapeutic targets in breast cancer: CDK4/6, Src, JAK/STAT, PARP, HDAC, and PI3K/AKT/mTOR pathways.
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- Pharmacogenomics & Personalized Medicine, 2014, v. 7, p. 203, doi. 10.2147/PGPM.S52762
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- Article
Activity of the nonreceptor tyrosine kinase Ack1 is regulated by tyrosine phosphorylation of its Mig6 homology region.
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- FEBS Letters, 2022, v. 596, n. 21, p. 2808, doi. 10.1002/1873-3468.14505
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- Article
Estrogen therapy induces an unfolded protein response to drive cell death in ER+ breast cancer.
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- Molecular Oncology, 2019, v. 13, n. 8, p. 1778, doi. 10.1002/1878-0261.12528
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- Article
Phosphorylation of Ack1 by the Receptor Tyrosine Kinase Mer.
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- Kinases & Phosphatases, 2023, v. 1, n. 3, p. 167, doi. 10.3390/kinasesphosphatases1030011
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- Article
Domain Architecture of the Nonreceptor Tyrosine Kinase Ack1.
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- Cells (2073-4409), 2023, v. 12, n. 6, p. 900, doi. 10.3390/cells12060900
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- Article
Comparison of ontogenetic trophic shift in two hake species, Merluccius capensis and Merluccius paradoxus, from the Northern Benguela Current ecosystem (Namibia) using stable isotope analysis.
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- Fisheries Oceanography, 2012, v. 21, n. 2/3, p. 215, doi. 10.1111/j.1365-2419.2012.00614.x
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- Article
Effects of Somatic Mutations in the C-Terminus of Insulin-Like Growth Factor 1 Receptor on Activity and Signaling.
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- Journal of Signal Transduction, 2012, p. 1, doi. 10.1155/2012/804801
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- Article
Small-molecule inhibition and activation-loop trans-phosphorylation of the IGF1 receptor.
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- EMBO Journal, 2008, v. 27, n. 14, p. 1985, doi. 10.1038/emboj.2008.116
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- Article
Treatment Strategies for Hormone Receptor-Positive, HER2-Negative Advanced Breast Cancer.
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- Journal of OncoPathology, 2014, v. 2, n. 2, p. 33, doi. 10.13032/tjop.2052-5931.100085
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- Article
The insulin and IGF1 receptor kinase domains are functional dimers in the activated state.
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- Nature Communications, 2015, v. 6, n. 3, p. 6406, doi. 10.1038/ncomms7406
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- Article
Autocrine IGF-I/insulin receptor axis compensates for inhibition of AKT in ER-positive breast cancer cells with resistance to estrogen deprivation.
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- Breast Cancer Research, 2013, v. 15, n. 4, p. 1, doi. 10.1186/bcr3449
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- Article
Autocrine IGF-I/insulin receptor axis compensates for inhibition of AKT in ER-positive breast cancer cells with resistance to estrogen deprivation.
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- 2013
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- Publication type:
- journal article
Initiating breast cancer by PIK3CA mutation.
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- 2012
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- journal article
Mutations in the phosphatidylinositol 3-kinase pathway: role in tumor progression and therapeutic implications in breast cancer.
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- 2011
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- journal article
Constitutive Activity in an Ancestral Form of Abl Tyrosine Kinase.
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- PLoS ONE, 2015, v. 10, n. 6, p. 1, doi. 10.1371/journal.pone.0131062
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- Article
Inhibition of mutationally activated HER2.
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- Chemical Biology & Drug Design, 2023, v. 101, n. 1, p. 87, doi. 10.1111/cbdd.14125
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- Article
Clinical Implementation of Novel Targeted Therapeutics in Advanced Breast Cancer.
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- Journal of Cellular Biochemistry, 2016, v. 117, n. 11, p. 2454, doi. 10.1002/jcb.25590
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- Article
Making Sense of Signal Transduction.
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- Science Signaling, 2009, v. 2, n. 101, p. 1, doi. 10.1126/scisignal.2101pe79
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- Article
Autoinhibition of the insulin-like growth factor I receptor by the juxtamembrane region
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- FEBS Letters, 2007, v. 581, n. 17, p. 3235, doi. 10.1016/j.febslet.2007.06.014
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- Article
Mutations in Mig6 reduce inhibition of the epidermal growth factor receptor.
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- FASEB Journal, 2024, v. 38, n. 22, p. 1, doi. 10.1096/fj.202401330R
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- Article
Biochemical characterization of the Drosophila insulin receptor kinase and longevity‐associated mutants.
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- FASEB Journal, 2024, v. 38, n. 1, p. 1, doi. 10.1096/fj.202301948R
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- Article
Cytokine sensitivity screening highlights BMP4 pathway signaling as a therapeutic opportunity in ERM<sup>+</sup> breast cancer.
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- FASEB Journal, 2019, v. 33, n. 2, p. 1644, doi. 10.1096/fj.201801241R
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- Article
Autophagy promotes escape from phosphatidylinositol 3-kinase inhibition in estrogen receptor-positive breast cancer.
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- FASEB Journal, 2018, v. 32, n. 3, p. 1222, doi. 10.1096/fj.201700477R
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- Article
Tumor pharmacokinetics and pharmacodynamics of the CDK4/6 inhibitor ribociclib in patients with recurrent glioblastoma.
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- Journal of Neuro-Oncology, 2019, v. 144, n. 3, p. 563, doi. 10.1007/s11060-019-03258-0
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- Article
The role of cancer cell bioenergetics in dormancy and drug resistance.
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- Cancer & Metastasis Reviews, 2023, v. 42, n. 1, p. 87, doi. 10.1007/s10555-023-10081-7
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- Article
A metal-binding motif implicated in RNA recognition by an aminoacyl-tRNA synthetase and by a retroviral gene product.
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- Molecular Microbiology, 1992, v. 6, n. 10, p. 1259, doi. 10.1111/j.1365-2958.1992.tb00846.x
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- Article
Structure, Function, and Regulation of the SRMS Tyrosine Kinase.
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- International Journal of Molecular Sciences, 2020, v. 21, n. 12, p. 4233, doi. 10.3390/ijms21124233
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- Article
Intrabody applications in neurological disorders: progress and future prospects
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- Molecular Therapy, 2005, v. 12, n. 3, p. 394, doi. 10.1016/j.ymthe.2005.04.003
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- Article
DNA vaccination against mutant huntingtin ameliorates the HDR6/2 diabetic phenotype
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- Molecular Therapy, 2003, v. 7, n. 5, p. 572, doi. 10.1016/S1525-0016(03)00063-7
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- Article
Maximizing the Benefit-Cost Ratio of Anthracyclines in Metastatic Breast Cancer: Case Report of a Patient with a Complete Response to High-Dose Doxorubicin.
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- Case Reports in Oncology, 2016, v. 9, n. 3, p. 840, doi. 10.1159/000453608
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- Article
Profiling of residual breast cancers after neoadjuvant chemotherapy identifies DUSP4 deficiency as a mechanism of drug resistance.
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- Nature Medicine, 2012, v. 18, n. 7, p. 1052, doi. 10.1038/nm.2795
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- Article
Cover Feature: Modulation of Src Kinase Activity by Selective Substrate Recognition with Pseudopeptidic Cages (Chem. Eur. J. 37/2021).
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- Chemistry - A European Journal, 2021, v. 27, n. 37, p. 9462, doi. 10.1002/chem.202101933
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- Article
Modulation of Src Kinase Activity by Selective Substrate Recognition with Pseudopeptidic Cages.
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- Chemistry - A European Journal, 2021, v. 27, n. 37, p. 9542, doi. 10.1002/chem.202100990
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- Article
Trailblazing Precision Oncology for Rare Tumor Subtypes.
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- Oncologist, 2018, v. 23, n. 2, p. 143, doi. 10.1634/theoncologist.2017-0494
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- Article
Implementation of a Molecular Tumor Board: The Impact on Treatment Decisions for 35 Patients Evaluated at Dartmouth-Hitchcock Medical Center.
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- Oncologist, 2015, v. 20, n. 9, p. 1011, doi. 10.1634/theoncologist.2015-0097
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- Article
Tumour, whole‐blood, plasma and tissue concentrations of metformin in lung cancer patients.
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- British Journal of Clinical Pharmacology, 2023, v. 89, n. 3, p. 1027, doi. 10.1111/bcp.15546
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- Article
TRIM33 Is a Co-Regulator of Estrogen Receptor Alpha.
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- Cancers, 2024, v. 16, n. 5, p. 845, doi. 10.3390/cancers16050845
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- Article
Metazoan-like signaling in a unicellular receptor tyrosine kinase.
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- BMC Biochemistry, 2013, v. 14, n. 1, p. 1, doi. 10.1186/1471-2091-14-4
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- Article
Regulation of Ack1 localization and activity by the amino-terminal SAM domain.
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- BMC Biochemistry, 2010, v. 11, p. 42, doi. 10.1186/1471-2091-11-42
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- Article
Hyperactivation of phosphatidylinositol-3 kinase promotes escape from hormone dependence in estrogen receptor-positive human breast cancer.
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- 2010
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- Publication type:
- journal article
Pan-Cancer Transcriptional Models Predicting Chemosensitivity in Human Tumors.
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- Cancer Informatics, 2021, p. 1, doi. 10.1177/11769351211002494
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- Article
Caged Thiophosphotyrosine Peptides.
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- Angewandte Chemie International Edition, 2001, v. 40, n. 16, p. 3049, doi. 10.1002/1521-3773(20010817)40:16<3049::AID-ANIE3049>3.0.CO;2-N
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- Article