Works by Miller, Timothy M.

Results: 60

Access for ALL in ALS: A large‐scale, inclusive, collaborative consortium to unlock the molecular and genetic mechanisms of amyotrophic lateral sclerosis.
Published in:
Muscle & Nerve, 2024, v. 70, n. 6, p. 1140, doi. 10.1002/mus.28244
By:
- Berry, James D.;
- Paganoni, Sabrina;
- Harms, Matthew B.;
- Shneider, Neil;
- Andrews, Jinsy;
- Miller, Timothy M.;
- Babu, Suma;
- Sherman, Alex V.;
- Harris, Brent T.;
- Provenzano, Frank A.;
- Phatnani, Hemali P.;
- Shefner, Jeremy;
- Garret, Mark A.;
- Ladha, Shaffeeq S.;
- Tsou, Amy Y.;
- Mohan, Praveena;
- Igne, Courtney;
- Bowser, Robert
Publication type:
Article
MicroRNA Profiling Reveals Marker of Motor Neuron Disease in ALS Models.
Published in:
Journal of Neuroscience, 2017, v. 37, n. 22, p. 5574, doi. 10.1523/JNEUROSCI.3582-16.2017
By:
- Hoye, Mariah L.;
- Koval, Erica D.;
- Wegener, Amy J.;
- Hyman, Theodore S.;
- Chengran Yang;
- O'Brien, David R.;
- Miller, Rebecca L.;
- Cole, Tracy;
- Schoch, Kathleen M.;
- Tao Shen;
- Tomonori Kunikata;
- Richard, Jean-Philippe;
- Gutmann, David H.;
- Maragakis, Nicholas J.;
- Kordasiewicz, Holly B.;
- Dougherty, Joseph D.;
- Miller, Timothy M.
Publication type:
Article
Antisense Reduction of Tau in Adult Mice Protects against Seizures.
Published in:
Journal of Neuroscience, 2013, v. 33, n. 31, p. 12887, doi. 10.1523/JNEUROSCI.2107-13.2013
By:
- DeVos, Sarah L.;
- Goncharoff, Dustin K.;
- Chen, Guo;
- Kebodeaux, Carey S.;
- Yamada, Kaoru;
- Stewart, Floy R.;
- Schuler, Dorothy R.;
- Maloney, Susan E.;
- Wozniak, David F.;
- Rigo, Frank;
- Bennett, C. Frank;
- Cirrito, John R.;
- Holtzman, David M.;
- Miller, Timothy M.
Publication type:
Article
Amyotrophic Lateral Sclerosis Clinical Trials and Interpretation of Functional End Points and Fluid Biomarkers: A Review.
Published in:
JAMA Neurology, 2022, v. 79, n. 12, p. 1312, doi. 10.1001/jamaneurol.2022.3282
By:
- Shefner, Jeremy M.;
- Bedlack, Richard;
- Andrews, Jinsy A.;
- Berry, James D.;
- Bowser, Robert;
- Brown, Robert;
- Glass, Jonathan D.;
- Maragakis, Nicholas J.;
- Miller, Timothy M.;
- Rothstein, Jeffrey D.;
- Cudkowicz, Merit E.
Publication type:
Article
CNS microRNA profiles: a database for cell type enriched microRNA expression across the mouse central nervous system.
Published in:
Scientific Reports, 2020, v. 10, n. 1, p. 1, doi. 10.1038/s41598-020-61307-5
By:
- Pomper, Nathan;
- Liu, Yating;
- Hoye, Mariah L.;
- Dougherty, Joseph D.;
- Miller, Timothy M.
Publication type:
Article
Evaluating the efficacy of purchased antisense oligonucleotides to reduce mouse and human tau in vivo.
Published in:
Frontiers in Molecular Neuroscience, 2023, p. 1, doi. 10.3389/fnmol.2023.1320182
By:
- Vemula, Pranav;
- Schoch, Kathleen M.;
- Miller, Timothy M.
Publication type:
Article
A Path to High-Efficiency Optical Coupling for HIRMES.
Published in:
Journal of Low Temperature Physics, 2018, v. 193, n. 5/6, p. 681, doi. 10.1007/s10909-018-1939-7
By:
- Miller, Timothy M.;
- Brown, Ari-David;
- Costen, Nicholas;
- Franz, David;
- Kutyrev, Alexander;
- Mikula, Vilem;
- Miller, Kevin H.;
- Moseley, S. Harvey;
- Oxborrow, Joseph;
- Rostem, Karwan;
- Wollack, Edward J.
Publication type:
Article
Poly(GR) and poly(GA) in cerebrospinal fluid as potential biomarkers for C9ORF72-ALS/FTD.
Published in:
Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-30387-4
By:
- Krishnan, Gopinath;
- Raitcheva, Denitza;
- Bartlett, Daniel;
- Prudencio, Mercedes;
- McKenna-Yasek, Diane M.;
- Douthwright, Catherine;
- Oskarsson, Björn E.;
- Ladha, Shafeeq;
- King, Oliver D.;
- Barmada, Sami J.;
- Miller, Timothy M.;
- Bowser, Robert;
- Watts, Jonathan K.;
- Petrucelli, Leonard;
- Brown, Robert H.;
- Kankel, Mark W.;
- Gao, Fen-Biao
Publication type:
Article
O.15: Distinct tau prion strains propagate in cells and mice and define different tauopathies.
Published in:
Prion, 2014, v. 8, p. 18
By:
- Sanders, David W.;
- Kaufman, Sarah K.;
- DeVos, Sarah L.;
- Sharma, Apurwa;
- Barker, Scarlett J.;
- Mirbaha, Hilda;
- Aimin Li;
- Miller, Timothy M.;
- Foley, Alex;
- Thorpe, Julian R.;
- Maina, Mahmoud Bukar;
- Serpell, Louise;
- Grinberg, Lea T.;
- Seeley, William W.;
- Diamond, Marc I.
Publication type:
Article
Fibroblast bioenergetics to classify amyotrophic lateral sclerosis patients.
Published in:
Molecular Neurodegeneration, 2017, v. 12, p. 1, doi. 10.1186/s13024-017-0217-5
By:
- Konrad, Csaba;
- Hibiki Kawamata;
- Bredvik, Kirsten G.;
- Arreguin, Andrea J.;
- Cajamarca, Steven A.;
- Hupf, Jonathan C.;
- Ravits, John M.;
- Miller, Timothy M.;
- Maragakis, Nicholas J.;
- Hales, Chadwick M.;
- Glass, Jonathan D.;
- Gross, Steven;
- Hiroshi Mitsumoto;
- Manfredi, Giovanni
Publication type:
Article
Oil and Gas Operations on Public Lands in the Marcellus Shale Region.
Published in:
Energy & Mineral Law Institute, 2011, n. 32, p. 516
By:
- Miller, Timothy M.;
- Griffith, M. David;
- McCrum, R. Timothy;
- Spina, Providence
Publication type:
Article
Is It a Deep Well or a Shallow Well and Who Cares?
Published in:
Energy & Mineral Law Institute, 2010, n. 31, p. 403
By:
- Miller, Timothy M.;
- Kauffman, Marsha Williams
Publication type:
Article
Using Smartphones to Reduce Research Burden in a Neurodegenerative Population and Assessing Participant Adherence: A Randomized Clinical Trial and Two Observational Studies.
Published in:
JMIR mHealth & uHealth, 2022, v. 10, n. 2, p. 1, doi. 10.2196/31877
By:
- Beukenhorst, Anna L.;
- Burke, Katherine M.;
- Scheier, Zoe;
- Miller, Timothy M.;
- Paganoni, Sabrina;
- Keegan, Mackenzie;
- Collins, Ella;
- Connaghan, Kathryn P.;
- Tay, Anna;
- Chan, James;
- Berry, James D.;
- Onnela, Jukka-Pekka
Publication type:
Article
Lumbar punctures are safe in patients with ALS and have a risk profile similar to that in the non‐ALS population.
Published in:
Muscle & Nerve, 2023, v. 68, n. 5, p. 771, doi. 10.1002/mus.27956
By:
- Kreple, Collin J.;
- Gajagowni, Saivaroon;
- Jockel‐Balsaratti, Jennifer;
- Bucelli, Robert C.;
- Miller, Timothy M.
Publication type:
Article
Incidence of amyotrophic lateral sclerosis in older adults.
Published in:
Muscle & Nerve, 2022, v. 66, n. 3, p. 289, doi. 10.1002/mus.27652
By:
- Camacho‐Soto, Alejandra;
- Searles Nielsen, Susan;
- Faust, Irene M.;
- Bucelli, Robert C.;
- Miller, Timothy M.;
- Racette, Brad A.
Publication type:
Article
Smartphone data during the COVID‐19 pandemic can quantify behavioral changes in people with ALS.
Published in:
Muscle & Nerve, 2021, v. 63, n. 2, p. 258, doi. 10.1002/mus.27110
By:
- Beukenhorst, Anna L.;
- Collins, Ella;
- Burke, Katherine M.;
- Rahman, Syed Minhajur;
- Clapp, Margaret;
- Konanki, Sai Charan;
- Paganoni, Sabrina;
- Miller, Timothy M.;
- Chan, James;
- Onnela, Jukka‐Pekka;
- Berry, James D.
Publication type:
Article
Amyotrophic lateral sclerosis care and research in the United States during the COVID-19 pandemic: Challenges and opportunities.
Published in:
2020
By:
- Andrews, Jinsy A.;
- Berry, James D.;
- Baloh, Robert H.;
- Carberry, Nathan;
- Cudkowicz, Merit E.;
- Dedi, Brixhilda;
- Glass, Jonathan;
- Maragakis, Nicholas J.;
- Miller, Timothy M.;
- Paganoni, Sabrina;
- Rothstein, Jeffrey D.;
- Shefner, Jeremy M.;
- Simmons, Zachary;
- Weiss, Michael D.;
- Bedlack, Richard S.
Publication type:
journal article
CK-2127107 amplifies skeletal muscle response to nerve activation in humans.
Published in:
2018
By:
- Andrews, Jinsy A.;
- Miller, Timothy M.;
- Vijayakumar, Vipin;
- Stoltz, Randall;
- James, Joyce K.;
- Meng, Lisa;
- Wolff, Andrew A.;
- Malik, Fady I.
Publication type:
journal article
Reply.
Published in:
2015
By:
- Paganoni, Sabrina;
- Schoenfeld, David;
- Shui, Amy;
- Cudkowicz, Merit;
- Miller, Timothy M.
Publication type:
Letter
Pre-morbid type 2 diabetes mellitus is not a prognostic factor in amyotrophic lateral sclerosis.
Published in:
Muscle & Nerve, 2015, v. 52, n. 3, p. 339, doi. 10.1002/mus.24688
By:
- Paganoni, Sabrina;
- Hyman, Theodore;
- Shui, Amy;
- Allred, Peggy;
- Harms, Matthew;
- Liu, Jingxia;
- Maragakis, Nicholas;
- Schoenfeld, David;
- Yu, Hong;
- Atassi, Nazem;
- Cudkowicz, Merit;
- Miller, Timothy M.
Publication type:
Article
Differential diagnosis of myotonic disorders.
Published in:
Muscle & Nerve, 2008, v. 37, n. 3, p. 293, doi. 10.1002/mus.20923
By:
- Miller, Timothy M.
Publication type:
Article
Phosphorylated neurofilament heavy chain: A biomarker of survival for C9ORF72-associated amyotrophic lateral sclerosis.
Published in:
2017
By:
- Gendron, Tania F.;
- Daughrity, Lillian M.;
- Heckman, Michael G.;
- Diehl, Nancy N.;
- Wuu, Joanne;
- Miller, Timothy M.;
- Pastor, Pau;
- Trojanowski, John Q.;
- Grossman, Murray;
- Berry, James D.;
- Hu, William T.;
- Ratti, Antonia;
- Benatar, Michael;
- Silani, Vincenzo;
- Glass, Jonathan D.;
- Floeter, Mary Kay;
- Jeromin, Andreas;
- Boylan, Kevin B.;
- Petrucelli, Leonard
Publication type:
journal article
Amyotrophic lateral sclerosis onset is influenced by the burden of rare variants in known amyotrophic lateral sclerosis genes.
Published in:
Annals of Neurology, 2015, v. 77, n. 1, p. 100, doi. 10.1002/ana.24306
By:
- Cady, Janet;
- Allred, Peggy;
- Bali, Taha;
- Pestronk, Alan;
- Goate, Alison;
- Miller, Timothy M.;
- Mitra, Robi D.;
- Ravits, John;
- Harms, Matthew B.;
- Baloh, Robert H.
Publication type:
Article
Progressive spinal axonal degeneration and slowness in ALS2‐deficient mice.
Published in:
Annals of Neurology, 2006, v. 60, n. 1, p. 95
By:
- Koji Yamanaka;
- Timothy M. Miller;
- Melissa McAlonis‐Downes;
- Seung Joo Chun;
- Don W. Cleveland
Publication type:
Article
Virus‐delivered small RNA silencing sustains strength in amyotrophic lateral sclerosis.
Published in:
Annals of Neurology, 2005, v. 57, n. 5, p. 773
By:
- Timothy M. Miller;
- Brian K. Kaspar;
- Geert J. Kops;
- Koji Yamanaka;
- Lindsey J. Christian;
- Fred H. Gage;
- Don W. Cleveland
Publication type:
Article
TREM2 Variant p.R47H as a Risk Factor for Sporadic Amyotrophic Lateral Sclerosis.
Published in:
JAMA Neurology, 2014, v. 71, n. 4, p. 449, doi. 10.1001/jamaneurol.2013.6237
By:
- Cady, Janet;
- Koval, Erica D.;
- Benitez, Bruno A.;
- Zaidman, Craig;
- Jockel-Balsarotti, Jennifer;
- Allred, Peggy;
- Baloh, Robert H.;
- Ravits, John;
- Simpson, Ericka;
- Appel, Stanley H.;
- Pestronk, Alan;
- Goate, Alison M.;
- Miller, Timothy M.;
- Cruchaga, Carlos;
- Harms, Matthew B.
Publication type:
Article
Body mass index is lower in asymptomatic C9orf72 expansion carriers but not in SOD1 pathogenic variant carriers compared to gene negatives.
Published in:
Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration, 2024, v. 25, n. 7/8, p. 672, doi. 10.1080/21678421.2024.2396831
By:
- Lee, Ikjae;
- Garret, Mark A.;
- Wuu, Joanne;
- Harrington, Elizabeth A.;
- Berry, James D.;
- Miller, Timothy M.;
- Harms, Matthew;
- Benatar, Michael;
- Shneider, Neil
Publication type:
Article
COURAGE-ALS: a randomized, double-blind phase 3 study designed to improve participant experience and increase the probability of success.
Published in:
Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration, 2023, v. 24, n. 5/6, p. 523, doi. 10.1080/21678421.2023.2216223
By:
- Shefner, Jeremy M.;
- Al-Chalabi, Ammar;
- Andrews, Jinsy A.;
- Chio, Adriano;
- De Carvalho, Mamede;
- Cockroft, Bettina M.;
- Corcia, Philippe;
- Couratier, Philippe;
- Cudkowicz, Merit E.;
- Genge, Angela;
- Hardiman, Orla;
- Heiman-Patterson, Terry;
- Henderson, Robert D.;
- Ingre, Caroline;
- Jackson, Carlayne E.;
- Johnston, Wendy;
- Lechtzin, Noah;
- Ludolph, Albert;
- Maragakis, Nicholas J.;
- Miller, Timothy M.
Publication type:
Article
MiToS and King's staging as clinical outcome measures in ALS: a retrospective analysis of the FORTITUDE-ALS trial.
Published in:
Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration, 2023, v. 24, n. 3/4, p. 304, doi. 10.1080/21678421.2022.2154678
By:
- Gebrehiwet, Paulos;
- Meng, Lisa;
- Rudnicki, Stacy A.;
- Sarocco, Phil;
- Wei, Jenny;
- Wolff, Andrew A.;
- Chiò, Adriano;
- Andrews, Jinsy A.;
- Genge, Angela;
- Jackson, Carlayne E.;
- Lechtzin, Noah;
- Miller, Timothy M.;
- Shefner, Jeremy M.
Publication type:
Article
Prescription and acceptance of durable medical equipment in FORTITUDE-ALS, a study of reldesemtiv in ALS: post hoc analyses of a randomized, double-blind, placebo-controlled clinical trial.
Published in:
Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration, 2022, v. 23, n. 3/4, p. 263, doi. 10.1080/21678421.2021.1946083
By:
- Rudnicki, Stacy A.;
- Andrews, Jinsy A.;
- Genge, Angela;
- Jackson, Carlayne;
- Lechtzin, Noah;
- Miller, Timothy M.;
- Cockroft, Bettina M.;
- Malik, Fady I.;
- Meng, Lisa;
- Wei, Jenny;
- Wolff, Andrew A.;
- Shefner, Jeremy M.
Publication type:
Article
A Phase 2, Double-Blind, Randomized, Dose-Ranging Trial Of Reldesemtiv In Patients With ALS.
Published in:
Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration, 2021, v. 22, n. 3/4, p. 287, doi. 10.1080/21678421.2020.1822410
By:
- Shefner, Jeremy M.;
- Andrews, Jinsy A.;
- Genge, Angela;
- Jackson, Carlayne;
- Lechtzin, Noah;
- Miller, Timothy M.;
- Cockroft, Bettina M.;
- Meng, Lisa;
- Wei, Jenny;
- Wolff, Andrew A.;
- Malik, Fady I.;
- Bodkin, Cynthia;
- Brooks, Benjamin R.;
- Caress, James;
- Dionne, Annie;
- Fee, Dominic;
- Goutman, Stephen A.;
- Goyal, Namita A.;
- Hardiman, Orla;
- Hayat, Ghazala
Publication type:
Article
Motor neuron-derived microRNAs cause astrocyte dysfunction in amyotrophic lateral sclerosis.
Published in:
2018
By:
- Hoye, Mariah L;
- Regan, Melissa R;
- Jensen, Leah A;
- Lake, Allison M;
- Reddy, Linga V;
- Vidensky, Svetlana;
- Richard, Jean-Philippe;
- Maragakis, Nicholas J;
- Rothstein, Jeffrey D;
- Dougherty, Joseph D;
- Miller, Timothy M
Publication type:
journal article
MicroRNA signature of central nervous system‐infiltrating dendritic cells in an animal model of multiple sclerosis.
Published in:
Immunology, 2018, v. 155, n. 1, p. 112, doi. 10.1111/imm.12934
By:
- Hoye, Mariah L.;
- Archambault, Angela S.;
- Gordon, Taylor M.;
- Oetjen, Landon K.;
- Cain, Matthew D.;
- Klein, Robyn S.;
- Crosby, Seth D.;
- Kim, Brian S.;
- Miller, Timothy M.;
- Wu, Gregory F.
Publication type:
Article
Plasma neurofilament light predicts mortality in patients with stroke.
Published in:
Science Translational Medicine, 2020, v. 12, n. 569, p. 1, doi. 10.1126/scitranslmed.aay1913
By:
- Gendron, Tania F.;
- Badi, Mohammed K.;
- Heckman, Michael G.;
- Jansen-West, Karen R.;
- Vilanilam, George K.;
- Johnson, Patrick W.;
- Burch, Alexander R.;
- Walton, Ronald L.;
- Ross, Owen A.;
- Brott, Thomas G.;
- Miller, Timothy M.;
- Berry, James D.;
- Nicholson, Katharine A.;
- Wszolek, Zbigniew K.;
- Oskarsson, Björn E.;
- Sheth, Kevin N.;
- Sansing, Lauren H.;
- Falcone, Guido J.;
- Cucchiara, Brett L.;
- Meschia, James F.
Publication type:
Article
Tau reduction prevents neuronal loss and reverses pathological tau deposition and seeding in mice with tauopathy.
Published in:
Science Translational Medicine, 2017, v. 9, n. 374, p. 1, doi. 10.1126/scitranslmed.aag0481
By:
- DeVos, Sarah L.;
- Miller, Rebecca L.;
- Schoch, Kathleen M.;
- Holmes, Brandon B.;
- Kebodeaux, Carey S.;
- Wegener, Amy J.;
- Guo Chen;
- Tao Shen;
- Tran, Hien;
- Nichols, Brandon;
- Zanardi, Tom A.;
- Kordasiewicz, Holly B.;
- Swayze, Eric E.;
- Bennett, C. Frank;
- Diamond, Marc I.;
- Miller, Timothy M.
Publication type:
Article
Health utilities and quality-adjusted life years for patients with amyotrophic lateral sclerosis receiving reldesemtiv or placebo in FORTITUDE-ALS.
Published in:
Journal of Medical Economics, 2023, v. 26, n. 1, p. 488, doi. 10.1080/13696998.2023.2192588
By:
- Gebrehiwet, Paulos;
- Meng, Lisa;
- Rudnicki, Stacy A.;
- Sarocco, Phil;
- Wei, Jenny;
- Wolff, Andrew A.;
- Butzner, Michael;
- Chiò, Adriano;
- Andrews, Jinsy A.;
- Genge, Angela;
- Hughes, Dyfrig A.;
- Jackson, Carlayne E.;
- Lechtzin, Noah;
- Miller, Timothy M.;
- Shefner, Jeremy M.
Publication type:
Article
Protective Effects of Lovastatin in a Population‐Based ALS Study and Mouse Model.
Published in:
Annals of Neurology, 2023, v. 93, n. 5, p. 881, doi. 10.1002/ana.26600
By:
- Kreple, Collin J.;
- Searles Nielsen, Susan;
- Schoch, Kathleen M.;
- Shen, Tao;
- Shabsovich, Mark;
- Song, Yizhe;
- Racette, Brad A.;
- Miller, Timothy M.
Publication type:
Article
Antisense oligonucleotides extend survival and reverse decrement in muscle response in ALS models.
Published in:
2018
By:
- McCampbell, Alex;
- Cole, Tracy;
- Wegener, Amy J.;
- Tomassy, Giulio S.;
- Setnicka, Amy;
- Farley, Brandon J.;
- Schoch, Kathleen M.;
- Hoye, Mariah L.;
- Shabsovich, Mark;
- Linhong Sun;
- Yi Luo;
- Mingdi Zhang;
- Sai Thankamony;
- Salzman, David W.;
- Cudkowicz, Merit;
- Graham, Danielle L.;
- Bennett, C. Frank;
- Kordasiewicz, Holly B.;
- Swayze, Eric E.;
- Miller, Timothy M.
Publication type:
journal article
Specific RNA interactions promote TDP‐43 multivalent phase separation and maintain liquid properties.
Published in:
EMBO Reports, 2021, v. 22, n. 12, p. 1, doi. 10.15252/embr.202153632
By:
- Grese, Zachary R;
- Bastos, Alliny CS;
- Mamede, Lohany D;
- French, Rachel L;
- Miller, Timothy M;
- Ayala, Yuna M
Publication type:
Article
Targeted ASO-mediated Atp1a2 knockdown in astrocytes reduces SOD1 aggregation and accelerates disease onset in mutant SOD1 mice.
Published in:
PLoS ONE, 2023, v. 18, n. 11, p. 1, doi. 10.1371/journal.pone.0294731
By:
- Iyer, Abhirami K.;
- Schoch, Kathleen M.;
- Verbeck, Anthony;
- Galasso, Grant;
- Chen, Hao;
- Smith, Sarah;
- Oldenborg, Anna;
- Miller, Timothy M.;
- Karch, Celeste M.;
- Bonni, Azad
Publication type:
Article
Has gene therapy for ALS arrived?
Published in:
Nature Medicine, 2003, v. 9, n. 10, p. 1256, doi. 10.1038/nm1003-1256
By:
- Miller, Timothy M.;
- Cleveland, Don W.
Publication type:
Article
Poly-dipeptides encoded by the C9ORF72 repeats block global protein translation.
Published in:
Human Molecular Genetics, 2016, v. 25, n. 9, p. 1803, doi. 10.1093/hmg/ddw052
By:
- Kohsuke Kanekura;
- Takuya Yagi;
- Cammack, Alexander J.;
- Mahadevan, Jana;
- Masahiko Kuroda;
- Harms, Matthew B.;
- Miller, Timothy M.;
- Urano, Fumihiko
Publication type:
Article
Method for widespread microRNA-155 inhibition prolongs survival in ALS-model mice.
Published in:
Human Molecular Genetics, 2013, v. 22, n. 20, p. 4127, doi. 10.1093/hmg/ddt261
By:
- Koval, Erica D.;
- Shaner, Carey;
- Zhang, Peter;
- du Maine, Xavier;
- Fischer, Kimberlee;
- Tay, Jia;
- Chau, B. Nelson;
- Wu, Gregory F.;
- Miller, Timothy M.
Publication type:
Article
In vivo kinetic approach reveals slow SOD1 turnover in the CNS.
Published in:
Journal of Clinical Investigation, 2015, v. 125, n. 7, p. 2772, doi. 10.1172/JCI80705
By:
- Crisp, Matthew J.;
- Mawuenyega, Kwasi C.;
- Patterson, Bruce W.;
- Reddy, Naveen C.;
- Chott, Robert;
- Self, Wade K.;
- Weihl, Conrad C.;
- Jockel-Balsarotti, Jennifer;
- Varadhachary, Arun S.;
- Bucelli, Robert C.;
- Yarasheski, Kevin E.;
- Bateman, Randall;
- Miller, Timothy M.
Publication type:
Article
Antisense oligonucleotide therapy for neurodegenerative disease.
Published in:
2006
By:
- Smith, Richard A.;
- Miller, Timothy M.;
- Yamanaka, Koji;
- Monia, Brett P.;
- Condon, Thomas P.;
- Hung, Gene;
- Lobsiger, Christian S.;
- Ward, Chris M.;
- McAlonis-Downes, Melissa;
- Wei, Hongbing;
- Wancewicz, Ed V.;
- Bennett, C. Frank;
- Cleveland, Don W.
Publication type:
journal article
Burst mitofusin activation reverses neuromuscular dysfunction in murine CMT2A.
Published in:
eLife, 2020, p. 1, doi. 10.7554/eLife.61119
By:
- Franco, Antonietta;
- Xiawei Dang;
- Walton, Emily K.;
- Ho, Joshua N.;
- Zablocka, Barbara;
- Ly, Cindy;
- Miller, Timothy M.;
- Baloh, Robert H.;
- Shy, Michael E.;
- Yoo, Andrew S.;
- Dorn II, Gerald W.
Publication type:
Article
Investigating 4R tau isoform imbalance as a mediator of astrocyte dysfunction in tauopathies.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.076609
By:
- Schoch, Kathleen M.;
- Ezerskiy, Lubov A.;
- Hu, Miwei;
- Beltcheva, Mariana;
- Rigo, Frank;
- Miller, Timothy M.
Publication type:
Article
Targeted Atp1a2 knockdown by antisense oligonucleotides leads to reduced SOD1 aggregation and accelerated disease progression in the SOD1*G93A mouse model of ALS.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, p. 1, doi. 10.1002/alz.058737
By:
- Iyer, Abhirami Kannan;
- Schoch, Kathleen M.;
- Oldenborg, Anna;
- Chen, Hao;
- Smith, Sarah E;
- Miller, Timothy M;
- Karch, Celeste M.;
- Bonni, Azad
Publication type:
Article
O4‐02‐02: TARGETING THE ALZHEIMER'S DISEASE‐ASSOCIATED RISK GENE, TREM2, WITH ANTISENSE OLIGONUCLEOTIDES.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2018, v. 14, p. P1402, doi. 10.1016/j.jalz.2018.06.2916
By:
- Schoch, Kathleen M.;
- Jafar-nejad, Paymaan;
- Rigo, Frank;
- Miller, Timothy M.
Publication type:
Article
O3‐01‐03: TAU KINETICS IN NEURONS AND IN THE HUMAN CNS.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2018, v. 14, p. P1008, doi. 10.1016/j.jalz.2018.06.2772
By:
- Sato, Chihiro;
- Barthélemy, Nicolas R.;
- Mawuenyega, Kwasi G.;
- Patterson, Bruce W.;
- Gordon, Brian A.;
- Kanaan, Nicholas M.;
- Benzinger, Tammie L.S.;
- Miller, Timothy M.;
- Karch, Celeste;
- Bateman, Randall J.
Publication type:
Article