Works matching AU Miller, Timothy M.

Results: 64

Management of Amyotrophic Lateral Sclerosis.

Published in:

Missouri Medicine, 2013, v. 110, n. 5, p. 417

By:

Bali, Taha;
Miller, Timothy M.

Publication type:

Article

Tofersen treatment leads to sustained stabilization of disease in SOD1 ALS in a "real‐world" setting.

Published in:

Annals of Clinical & Translational Neurology, 2025, v. 12, n. 2, p. 311, doi. 10.1002/acn3.52264

By:

Smith, Sean E.;
McCoy‐Gross, Kelly;
Malcolm, Amber;
Oranski, Jeri;
Markway, Jesse W.;
Miller, Timothy M.;
Bucelli, Robert C.

Publication type:

Article

Protein kinetics of superoxide dismutase‐1 in familial and sporadic amyotrophic lateral sclerosis.

Published in:

Annals of Clinical & Translational Neurology, 2023, v. 10, n. 6, p. 1012, doi. 10.1002/acn3.51784

By:

Ly, Cindy V.;
Ireland, Margaret D.;
Self, Wade K.;
Bollinger, James;
Jockel‐Balsarotti, Jennifer;
Herzog, Hillary;
Allred, Peggy;
Miller, Leah;
Doyle, Michael;
Anez‐Bruzual, Isabel;
Trikamji, Bhavesh;
Hyman, Ted;
Kung, Tyler;
Nicholson, Katherine;
Bucelli, Robert C.;
Patterson, Bruce W.;
Bateman, Randall J.;
Miller, Timothy M.

Publication type:

Article

Protein production is an early biomarker for RNA‐targeted therapies.

Published in:

Annals of Clinical & Translational Neurology, 2018, v. 5, n. 12, p. 1492, doi. 10.1002/acn3.657

By:

Self, Wade K.;
Schoch, Kathleen M.;
Alex, Jacob;
Barthélemy, Nicolas;
Bollinger, James G.;
Sato, Chihiro;
Cole, Tracy;
Kordasiewicz, Holly B.;
Swayze, Eric;
Bateman, Randall J.;
Miller, Timothy M.

Publication type:

Article

Amyotrophic Lateral Sclerosis Clinical Trials and Interpretation of Functional End Points and Fluid Biomarkers: A Review.

Published in:

JAMA Neurology, 2022, v. 79, n. 12, p. 1312, doi. 10.1001/jamaneurol.2022.3282

By:

Shefner, Jeremy M.;
Bedlack, Richard;
Andrews, Jinsy A.;
Berry, James D.;
Bowser, Robert;
Brown, Robert;
Glass, Jonathan D.;
Maragakis, Nicholas J.;
Miller, Timothy M.;
Rothstein, Jeffrey D.;
Cudkowicz, Merit E.

Publication type:

Article

TREM2 Variant p.R47H as a Risk Factor for Sporadic Amyotrophic Lateral Sclerosis.

Published in:

JAMA Neurology, 2014, v. 71, n. 4, p. 449, doi. 10.1001/jamaneurol.2013.6237

By:

Cady, Janet;
Koval, Erica D.;
Benitez, Bruno A.;
Zaidman, Craig;
Jockel-Balsarotti, Jennifer;
Allred, Peggy;
Baloh, Robert H.;
Ravits, John;
Simpson, Ericka;
Appel, Stanley H.;
Pestronk, Alan;
Goate, Alison M.;
Miller, Timothy M.;
Cruchaga, Carlos;
Harms, Matthew B.

Publication type:

Article

Body mass index is lower in asymptomatic C9orf72 expansion carriers but not in SOD1 pathogenic variant carriers compared to gene negatives.

Published in:

Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration, 2024, v. 25, n. 7/8, p. 672, doi. 10.1080/21678421.2024.2396831

By:

Lee, Ikjae;
Garret, Mark A.;
Wuu, Joanne;
Harrington, Elizabeth A.;
Berry, James D.;
Miller, Timothy M.;
Harms, Matthew;
Benatar, Michael;
Shneider, Neil

Publication type:

Article

MiToS and King's staging as clinical outcome measures in ALS: a retrospective analysis of the FORTITUDE-ALS trial.

Published in:

Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration, 2023, v. 24, n. 3/4, p. 304, doi. 10.1080/21678421.2022.2154678

By:

Gebrehiwet, Paulos;
Meng, Lisa;
Rudnicki, Stacy A.;
Sarocco, Phil;
Wei, Jenny;
Wolff, Andrew A.;
Chiò, Adriano;
Andrews, Jinsy A.;
Genge, Angela;
Jackson, Carlayne E.;
Lechtzin, Noah;
Miller, Timothy M.;
Shefner, Jeremy M.

Publication type:

Article

COURAGE-ALS: a randomized, double-blind phase 3 study designed to improve participant experience and increase the probability of success.

Published in:

Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration, 2023, v. 24, n. 5/6, p. 523, doi. 10.1080/21678421.2023.2216223

By:

Shefner, Jeremy M.;
Al-Chalabi, Ammar;
Andrews, Jinsy A.;
Chio, Adriano;
De Carvalho, Mamede;
Cockroft, Bettina M.;
Corcia, Philippe;
Couratier, Philippe;
Cudkowicz, Merit E.;
Genge, Angela;
Hardiman, Orla;
Heiman-Patterson, Terry;
Henderson, Robert D.;
Ingre, Caroline;
Jackson, Carlayne E.;
Johnston, Wendy;
Lechtzin, Noah;
Ludolph, Albert;
Maragakis, Nicholas J.;
Miller, Timothy M.

Publication type:

Article

Prescription and acceptance of durable medical equipment in FORTITUDE-ALS, a study of reldesemtiv in ALS: post hoc analyses of a randomized, double-blind, placebo-controlled clinical trial.

Published in:

Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration, 2022, v. 23, n. 3/4, p. 263, doi. 10.1080/21678421.2021.1946083

By:

Rudnicki, Stacy A.;
Andrews, Jinsy A.;
Genge, Angela;
Jackson, Carlayne;
Lechtzin, Noah;
Miller, Timothy M.;
Cockroft, Bettina M.;
Malik, Fady I.;
Meng, Lisa;
Wei, Jenny;
Wolff, Andrew A.;
Shefner, Jeremy M.

Publication type:

Article

A Phase 2, Double-Blind, Randomized, Dose-Ranging Trial Of Reldesemtiv In Patients With ALS.

Published in:

Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration, 2021, v. 22, n. 3/4, p. 287, doi. 10.1080/21678421.2020.1822410

By:

Shefner, Jeremy M.;
Andrews, Jinsy A.;
Genge, Angela;
Jackson, Carlayne;
Lechtzin, Noah;
Miller, Timothy M.;
Cockroft, Bettina M.;
Meng, Lisa;
Wei, Jenny;
Wolff, Andrew A.;
Malik, Fady I.;
Bodkin, Cynthia;
Brooks, Benjamin R.;
Caress, James;
Dionne, Annie;
Fee, Dominic;
Goutman, Stephen A.;
Goyal, Namita A.;
Hardiman, Orla;
Hayat, Ghazala

Publication type:

Article

Health utilities and quality-adjusted life years for patients with amyotrophic lateral sclerosis receiving reldesemtiv or placebo in FORTITUDE-ALS.

Published in:

Journal of Medical Economics, 2023, v. 26, n. 1, p. 488, doi. 10.1080/13696998.2023.2192588

By:

Gebrehiwet, Paulos;
Meng, Lisa;
Rudnicki, Stacy A.;
Sarocco, Phil;
Wei, Jenny;
Wolff, Andrew A.;
Butzner, Michael;
Chiò, Adriano;
Andrews, Jinsy A.;
Genge, Angela;
Hughes, Dyfrig A.;
Jackson, Carlayne E.;
Lechtzin, Noah;
Miller, Timothy M.;
Shefner, Jeremy M.

Publication type:

Article

Has gene therapy for ALS arrived?

Published in:

Nature Medicine, 2003, v. 9, n. 10, p. 1256, doi. 10.1038/nm1003-1256

By:

Miller, Timothy M.;
Cleveland, Don W.

Publication type:

Article

Poly(GR) and poly(GA) in cerebrospinal fluid as potential biomarkers for C9ORF72-ALS/FTD.

Published in:

Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-30387-4

By:

Krishnan, Gopinath;
Raitcheva, Denitza;
Bartlett, Daniel;
Prudencio, Mercedes;
McKenna-Yasek, Diane M.;
Douthwright, Catherine;
Oskarsson, Björn E.;
Ladha, Shafeeq;
King, Oliver D.;
Barmada, Sami J.;
Miller, Timothy M.;
Bowser, Robert;
Watts, Jonathan K.;
Petrucelli, Leonard;
Brown, Robert H.;
Kankel, Mark W.;
Gao, Fen-Biao

Publication type:

Article

Differential diagnosis of myotonic disorders.

Published in:

Muscle & Nerve, 2008, v. 37, n. 3, p. 293, doi. 10.1002/mus.20923

By:

Miller, Timothy M.

Publication type:

Article

Poly-dipeptides encoded by the C9ORF72 repeats block global protein translation.

Published in:

Human Molecular Genetics, 2016, v. 25, n. 9, p. 1803, doi. 10.1093/hmg/ddw052

By:

Kohsuke Kanekura;
Takuya Yagi;
Cammack, Alexander J.;
Mahadevan, Jana;
Masahiko Kuroda;
Harms, Matthew B.;
Miller, Timothy M.;
Urano, Fumihiko

Publication type:

Article

Method for widespread microRNA-155 inhibition prolongs survival in ALS-model mice.

Published in:

Human Molecular Genetics, 2013, v. 22, n. 20, p. 4127, doi. 10.1093/hmg/ddt261

By:

Koval, Erica D.;
Shaner, Carey;
Zhang, Peter;
du Maine, Xavier;
Fischer, Kimberlee;
Tay, Jia;
Chau, B. Nelson;
Wu, Gregory F.;
Miller, Timothy M.

Publication type:

Article

Plasma neurofilament light predicts mortality in patients with stroke.

Published in:

Science Translational Medicine, 2020, v. 12, n. 569, p. 1, doi. 10.1126/scitranslmed.aay1913

By:

Gendron, Tania F.;
Badi, Mohammed K.;
Heckman, Michael G.;
Jansen-West, Karen R.;
Vilanilam, George K.;
Johnson, Patrick W.;
Burch, Alexander R.;
Walton, Ronald L.;
Ross, Owen A.;
Brott, Thomas G.;
Miller, Timothy M.;
Berry, James D.;
Nicholson, Katharine A.;
Wszolek, Zbigniew K.;
Oskarsson, Björn E.;
Sheth, Kevin N.;
Sansing, Lauren H.;
Falcone, Guido J.;
Cucchiara, Brett L.;
Meschia, James F.

Publication type:

Article

Timing of diagnosis of patients with pompe disease: Data from the pompe registry.

Published in:

American Journal of Medical Genetics. Part A, 2013, v. 161A, n. 10, p. 2431, doi. 10.1002/ajmg.a.36110

By:

Kishnani, Priya S.;
Amartino, Hernán M.;
Lindberg, Christopher;
Miller, Timothy M.;
Wilson, Amanda;
Keutzer, Joan

Publication type:

Article

Motor neuron-derived microRNAs cause astrocyte dysfunction in amyotrophic lateral sclerosis.

Published in:

2018

By:

Hoye, Mariah L;
Regan, Melissa R;
Jensen, Leah A;
Lake, Allison M;
Reddy, Linga V;
Vidensky, Svetlana;
Richard, Jean-Philippe;
Maragakis, Nicholas J;
Rothstein, Jeffrey D;
Dougherty, Joseph D;
Miller, Timothy M

Publication type:

journal article

MicroRNA Profiling Reveals Marker of Motor Neuron Disease in ALS Models.

Published in:

Journal of Neuroscience, 2017, v. 37, n. 22, p. 5574, doi. 10.1523/JNEUROSCI.3582-16.2017

By:

Hoye, Mariah L.;
Koval, Erica D.;
Wegener, Amy J.;
Hyman, Theodore S.;
Chengran Yang;
O'Brien, David R.;
Miller, Rebecca L.;
Cole, Tracy;
Schoch, Kathleen M.;
Tao Shen;
Tomonori Kunikata;
Richard, Jean-Philippe;
Gutmann, David H.;
Maragakis, Nicholas J.;
Kordasiewicz, Holly B.;
Dougherty, Joseph D.;
Miller, Timothy M.

Publication type:

Article

Antisense Reduction of Tau in Adult Mice Protects against Seizures.

Published in:

Journal of Neuroscience, 2013, v. 33, n. 31, p. 12887, doi. 10.1523/JNEUROSCI.2107-13.2013

By:

DeVos, Sarah L.;
Goncharoff, Dustin K.;
Chen, Guo;
Kebodeaux, Carey S.;
Yamada, Kaoru;
Stewart, Floy R.;
Schuler, Dorothy R.;
Maloney, Susan E.;
Wozniak, David F.;
Rigo, Frank;
Bennett, C. Frank;
Cirrito, John R.;
Holtzman, David M.;
Miller, Timothy M.

Publication type:

Article

Protective Effects of Lovastatin in a Population‐Based ALS Study and Mouse Model.

Published in:

Annals of Neurology, 2023, v. 93, n. 5, p. 881, doi. 10.1002/ana.26600

By:

Kreple, Collin J.;
Searles Nielsen, Susan;
Schoch, Kathleen M.;
Shen, Tao;
Shabsovich, Mark;
Song, Yizhe;
Racette, Brad A.;
Miller, Timothy M.

Publication type:

Article

Phosphorylated neurofilament heavy chain: A biomarker of survival for C9ORF72-associated amyotrophic lateral sclerosis.

Published in:

2017

By:

Gendron, Tania F.;
Daughrity, Lillian M.;
Heckman, Michael G.;
Diehl, Nancy N.;
Wuu, Joanne;
Miller, Timothy M.;
Pastor, Pau;
Trojanowski, John Q.;
Grossman, Murray;
Berry, James D.;
Hu, William T.;
Ratti, Antonia;
Benatar, Michael;
Silani, Vincenzo;
Glass, Jonathan D.;
Floeter, Mary Kay;
Jeromin, Andreas;
Boylan, Kevin B.;
Petrucelli, Leonard

Publication type:

journal article

Amyotrophic lateral sclerosis onset is influenced by the burden of rare variants in known amyotrophic lateral sclerosis genes.

Published in:

Annals of Neurology, 2015, v. 77, n. 1, p. 100, doi. 10.1002/ana.24306

By:

Cady, Janet;
Allred, Peggy;
Bali, Taha;
Pestronk, Alan;
Goate, Alison;
Miller, Timothy M.;
Mitra, Robi D.;
Ravits, John;
Harms, Matthew B.;
Baloh, Robert H.

Publication type:

Article

Investigating 4R tau isoform imbalance as a mediator of astrocyte dysfunction in tauopathies.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.076609

By:

Schoch, Kathleen M.;
Ezerskiy, Lubov A.;
Hu, Miwei;
Beltcheva, Mariana;
Rigo, Frank;
Miller, Timothy M.

Publication type:

Article

Targeted Atp1a2 knockdown by antisense oligonucleotides leads to reduced SOD1 aggregation and accelerated disease progression in the SOD1*G93A mouse model of ALS.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, p. 1, doi. 10.1002/alz.058737

By:

Iyer, Abhirami Kannan;
Schoch, Kathleen M.;
Oldenborg, Anna;
Chen, Hao;
Smith, Sarah E;
Miller, Timothy M;
Karch, Celeste M.;
Bonni, Azad

Publication type:

Article

O4‐02‐02: TARGETING THE ALZHEIMER'S DISEASE‐ASSOCIATED RISK GENE, TREM2, WITH ANTISENSE OLIGONUCLEOTIDES.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2018, v. 14, p. P1402, doi. 10.1016/j.jalz.2018.06.2916

By:

Schoch, Kathleen M.;
Jafar-nejad, Paymaan;
Rigo, Frank;
Miller, Timothy M.

Publication type:

Article

O3‐01‐03: TAU KINETICS IN NEURONS AND IN THE HUMAN CNS.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2018, v. 14, p. P1008, doi. 10.1016/j.jalz.2018.06.2772

By:

Sato, Chihiro;
Barthélemy, Nicolas R.;
Mawuenyega, Kwasi G.;
Patterson, Bruce W.;
Gordon, Brian A.;
Kanaan, Nicholas M.;
Benzinger, Tammie L.S.;
Miller, Timothy M.;
Karch, Celeste;
Bateman, Randall J.

Publication type:

Article

Antisense oligonucleotide therapy for neurodegenerative disease.

Published in:

2006

By:

Smith, Richard A.;
Miller, Timothy M.;
Yamanaka, Koji;
Monia, Brett P.;
Condon, Thomas P.;
Hung, Gene;
Lobsiger, Christian S.;
Ward, Chris M.;
McAlonis-Downes, Melissa;
Wei, Hongbing;
Wancewicz, Ed V.;
Bennett, C. Frank;
Cleveland, Don W.

Publication type:

journal article

Using Smartphones to Reduce Research Burden in a Neurodegenerative Population and Assessing Participant Adherence: A Randomized Clinical Trial and Two Observational Studies.

Published in:

JMIR mHealth & uHealth, 2022, v. 10, n. 2, p. 1, doi. 10.2196/31877

By:

Beukenhorst, Anna L.;
Burke, Katherine M.;
Scheier, Zoe;
Miller, Timothy M.;
Paganoni, Sabrina;
Keegan, Mackenzie;
Collins, Ella;
Connaghan, Kathryn P.;
Tay, Anna;
Chan, James;
Berry, James D.;
Onnela, Jukka-Pekka

Publication type:

Article

Progressive spinal axonal degeneration and slowness in ALS2‐deficient mice.

Published in:

Annals of Neurology, 2006, v. 60, n. 1, p. 95

By:

Koji Yamanaka;
Timothy M. Miller;
Melissa McAlonis‐Downes;
Seung Joo Chun;
Don W. Cleveland

Publication type:

Article

Virus‐delivered small RNA silencing sustains strength in amyotrophic lateral sclerosis.

Published in:

Annals of Neurology, 2005, v. 57, n. 5, p. 773

By:

Timothy M. Miller;
Brian K. Kaspar;
Geert J. Kops;
Koji Yamanaka;
Lindsey J. Christian;
Fred H. Gage;
Don W. Cleveland

Publication type:

Article

IN VIVO TAU IMAGING BY POSITRON EMISSION TOMOGRAPHY IN PATIENTS WITH C9ORF72 HEXANUCLEOTIDE REPEAT EXPANSIONS.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2017, v. 13, p. P904, doi. 10.1016/j.jalz.2017.07.318

By:

Ly, Cindy V.;
Koenig, Lauren;
Beaumont, Helen;
Gordon, Brian A.;
Christensen, Jon;
Su, Yi;
Nelson, Brittany;
Jockel-Balsarotti, Jennifer;
Drain, Caroline;
Jerome, Gina;
Fagan, Anne M.;
Harms, Matthew;
Benzinger, Tammie L.S.;
Miller, Timothy M.;
Ances, Beau M.

Publication type:

Article

DISCOVERY AND EARLY CLINICAL DEVELOPMENT OF IONIS-MAPTRX, THE FIRST TAU-LOWERING ANTISENSE OLIGONUCLEOTIDE, IN PATIENTS WITH MILD AD.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2017, v. 13, p. P600, doi. 10.1016/j.jalz.2017.07.242

By:

Lane, Roger M.;
Kordasiewicz, Holly B.;
Smith, Anne;
Mignon, Laurence;
Miller, Timothy M.;
Mummery, Catherine J.;
Andreasen, Niels;
Narayanan, Padma;
Swayze, Eric;
Norris, Daniel A.;
Fitzsimmons, Bethany;
Bennett, C Frank

Publication type:

Article

Tau kinetics in the human cns.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2015, v. 11, n. 7, p. P334, doi. 10.1016/j.jalz.2015.08.160

By:

Sato, Chihiro;
Mawuenyega, Kwasi;
Barthelemy, Nicolas;
Patterson, Bruce W.;
Kasten, Tom;
Jockel-Balsarotti, Jennifer;
Chott, Robert;
Yarasheski, Kevin E.;
Miller, Timothy M.;
Bateman, Randall

Publication type:

Article

Tau splicing in vivo: Application in mouse models of tauopathy confers functional and pathological changes.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2015, v. 11, n. 7, p. P226, doi. 10.1016/j.jalz.2015.07.256

By:

Schoch, Kathleen M.;
DeVos, Sarah L.;
Miller, Rebecca L.;
Kebodeaux, Carey S.;
Norrbom, Michaela;
Chun, Seung;
Dawson, Hana N.;
Rigo, Frank;
Bennett, C. Frank;
Miller, Timothy M.

Publication type:

Article

Antisense oligonucleotides as therapeutic agents.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2014, v. 10, p. P201, doi. 10.1016/j.jalz.2014.04.246

By:

Miller, Timothy M.

Publication type:

Article

Oil and Gas Operations on Public Lands in the Marcellus Shale Region.

Published in:

Energy & Mineral Law Institute, 2011, n. 32, p. 516

By:

Miller, Timothy M.;
Griffith, M. David;
McCrum, R. Timothy;
Spina, Providence

Publication type:

Article

Is It a Deep Well or a Shallow Well and Who Cares?

Published in:

Energy & Mineral Law Institute, 2010, n. 31, p. 403

By:

Miller, Timothy M.;
Kauffman, Marsha Williams

Publication type:

Article

Specific RNA interactions promote TDP‐43 multivalent phase separation and maintain liquid properties.

Published in:

EMBO Reports, 2021, v. 22, n. 12, p. 1, doi. 10.15252/embr.202153632

By:

Grese, Zachary R;
Bastos, Alliny CS;
Mamede, Lohany D;
French, Rachel L;
Miller, Timothy M;
Ayala, Yuna M

Publication type:

Article

Fibroblast bioenergetics to classify amyotrophic lateral sclerosis patients.

Published in:

Molecular Neurodegeneration, 2017, v. 12, p. 1, doi. 10.1186/s13024-017-0217-5

By:

Konrad, Csaba;
Hibiki Kawamata;
Bredvik, Kirsten G.;
Arreguin, Andrea J.;
Cajamarca, Steven A.;
Hupf, Jonathan C.;
Ravits, John M.;
Miller, Timothy M.;
Maragakis, Nicholas J.;
Hales, Chadwick M.;
Glass, Jonathan D.;
Gross, Steven;
Hiroshi Mitsumoto;
Manfredi, Giovanni

Publication type:

Article

Antisense oligonucleotides extend survival and reverse decrement in muscle response in ALS models.

Published in:

2018

By:

McCampbell, Alex;
Cole, Tracy;
Wegener, Amy J.;
Tomassy, Giulio S.;
Setnicka, Amy;
Farley, Brandon J.;
Schoch, Kathleen M.;
Hoye, Mariah L.;
Shabsovich, Mark;
Linhong Sun;
Yi Luo;
Mingdi Zhang;
Sai Thankamony;
Salzman, David W.;
Cudkowicz, Merit;
Graham, Danielle L.;
Bennett, C. Frank;
Kordasiewicz, Holly B.;
Swayze, Eric E.;
Miller, Timothy M.

Publication type:

journal article

In vivo kinetic approach reveals slow SOD1 turnover in the CNS.

Published in:

Journal of Clinical Investigation, 2015, v. 125, n. 7, p. 2772, doi. 10.1172/JCI80705

By:

Crisp, Matthew J.;
Mawuenyega, Kwasi C.;
Patterson, Bruce W.;
Reddy, Naveen C.;
Chott, Robert;
Self, Wade K.;
Weihl, Conrad C.;
Jockel-Balsarotti, Jennifer;
Varadhachary, Arun S.;
Bucelli, Robert C.;
Yarasheski, Kevin E.;
Bateman, Randall;
Miller, Timothy M.

Publication type:

Article

Reldesemtiv in Amyotrophic Lateral Sclerosis: Results From the COURAGE-ALS Randomized Clinical Trial.

Published in:

JAMA Neurology, 2025, v. 82, n. 5, p. 477, doi. 10.1001/jamaneurol.2025.0241

By:

Shefner, Jeremy M.;
Cudkowicz, Merit E.;
Genge, Angela;
Hardiman, Orla;
Al-Chalabi, Ammar;
Andrews, Jinsy A.;
Chio, Adriano;
Corcia, Philippe;
Couratier, Philippe;
de Carvalho, Mamede;
Heiman-Patterson, Terry;
Henderson, Robert D.;
Ingre, Caroline;
Johnston, Wendy;
Ludolph, Albert;
Maragakis, Nicholas J.;
Miller, Timothy M.;
Mora, Jesus S.;
Petri, Susanne;
Simmons, Zachary

Publication type:

Article

Targeted ASO-mediated Atp1a2 knockdown in astrocytes reduces SOD1 aggregation and accelerates disease onset in mutant SOD1 mice.

Published in:

PLoS ONE, 2023, v. 18, n. 11, p. 1, doi. 10.1371/journal.pone.0294731

By:

Iyer, Abhirami K.;
Schoch, Kathleen M.;
Verbeck, Anthony;
Galasso, Grant;
Chen, Hao;
Smith, Sarah;
Oldenborg, Anna;
Miller, Timothy M.;
Karch, Celeste M.;
Bonni, Azad

Publication type:

Article

Network analysis of the cerebrospinal fluid proteome reveals shared and unique differences between sporadic and familial forms of amyotrophic lateral sclerosis.

Published in:

Molecular Neurodegeneration, 2025, v. 20, n. 1, p. 1, doi. 10.1186/s13024-025-00838-9

By:

Trautwig, Adam N.;
Fox, Edward J.;
Dammer, Eric B.;
Shantaraman, Anantharaman;
Ping, Lingyan;
Duong, Duc M.;
Watson, Caroline M.;
Wu, Fang;
Asress, Seneshaw;
Guo, Qi;
Levey, Allan I.;
Lah, James J.;
Verde, Federico;
Doretti, Alberto;
Ratti, Antonia;
Ticozzi, Nicola;
Ly, Cindy V.;
Miller, Timothy M.;
Garret, Mark A.;
Berry, James D.

Publication type:

Article

Access for ALL in ALS: A large‐scale, inclusive, collaborative consortium to unlock the molecular and genetic mechanisms of amyotrophic lateral sclerosis.

Published in:

Muscle & Nerve, 2024, v. 70, n. 6, p. 1140, doi. 10.1002/mus.28244

By:

Berry, James D.;
Paganoni, Sabrina;
Harms, Matthew B.;
Shneider, Neil;
Andrews, Jinsy;
Miller, Timothy M.;
Babu, Suma;
Sherman, Alex V.;
Harris, Brent T.;
Provenzano, Frank A.;
Phatnani, Hemali P.;
Shefner, Jeremy;
Garret, Mark A.;
Ladha, Shaffeeq S.;
Tsou, Amy Y.;
Mohan, Praveena;
Igne, Courtney;
Bowser, Robert

Publication type:

Article

Lumbar punctures are safe in patients with ALS and have a risk profile similar to that in the non‐ALS population.

Published in:

Muscle & Nerve, 2023, v. 68, n. 5, p. 771, doi. 10.1002/mus.27956

By:

Kreple, Collin J.;
Gajagowni, Saivaroon;
Jockel‐Balsaratti, Jennifer;
Bucelli, Robert C.;
Miller, Timothy M.

Publication type:

Article

Incidence of amyotrophic lateral sclerosis in older adults.

Published in:

Muscle & Nerve, 2022, v. 66, n. 3, p. 289, doi. 10.1002/mus.27652

By:

Camacho‐Soto, Alejandra;
Searles Nielsen, Susan;
Faust, Irene M.;
Bucelli, Robert C.;
Miller, Timothy M.;
Racette, Brad A.

Publication type:

Article