Works by Miller, Susan P.

Results: 61

Low ATM protein expression and depletion of p53 correlates with olaparib sensitivity in gastric cancer cell lines.

Published in:

Cell Cycle, 2014, v. 13, n. 13, p. 2129, doi. 10.4161/cc.29212

By:

Kubota, Eiji;
Williamson, Christopher T.;
Ruiqiong Ye;
elegbede, Anifat;
Peterson, Lars;
Lees-Miller, Susan P.;
Bebb, D. Gwyn

Publication type:

Article

Predicting PARP inhibitor sensitivity and resistance.

Published in:

Cell Cycle, 2012, v. 11, n. 22, p. 4110, doi. 10.4161/cc.22604

By:

Bebb, D. Gwyn;
Lees-Miller, Susan P.

Publication type:

Article

Correction: Combined poly-ADP ribose polymerase and ataxia-telangiectasia mutated/Rad3-related inhibition targets ataxia-telangiectasia mutated-deficient lung cancer cells.

Published in:

2020

By:

Jette, Nicholas R.;
Radhamani, Suraj;
Arthur, Greydon;
Ye, Ruiqiong;
Goutam, Siddhartha;
Bolyos, Anthony;
Petersen, Lars F.;
Bose, Pinaki;
Bebb, D. Gwyn;
Lees-Miller, Susan P.

Publication type:

corrected article

Combined poly-ADP ribose polymerase and ataxia-telangiectasia mutated/Rad3-related inhibition targets ataxia-telangiectasia mutated-deficient lung cancer cells.

Published in:

2019

By:

Jette, Nicholas R.;
Radhamani, Suraj;
Arthur, Greydon;
Ye, Ruiqiong;
Goutam, Siddhartha;
Bolyos, Anthony;
Petersen, Lars F.;
Bose, Pinaki;
Bebb, D. Gwyn;
Lees-Miller, Susan P.

Publication type:

journal article

Exploring the Efficacy of Online Strategy Instruction for Improving the Reading Abilities of Students with Learning Disabilities.

Published in:

Journal of Special Education Technology, 2012, v. 27, n. 1, p. 33, doi. 10.1177/016264341202700103

By:

Fitzgerald, Nancy S.;
Miller, Susan P.;
Higgins, Kyle;
Pierce, Tom;
Tandy, Dick

Publication type:

Article

Developing Computation Competence Among Students Who Struggle With Mathematics.

Published in:

Teaching Exceptional Children, 2011, v. 44, n. 2, p. 38, doi. 10.1177/004005991104400204

By:

Miller, Susan P.;
Stringfellow, Jennifer L.;
Kaffar, Bradley J.;
Ferreira, Danielle;
Mancl, Dustin B.

Publication type:

Article

Helping Students With Disabilities Understand What Mathematics Means.

Published in:

Teaching Exceptional Children, 2006, v. 39, n. 1, p. 28, doi. 10.1177/004005990603900105

By:

Miller, Susan P.;
Hudson, Pamela J.

Publication type:

Article

Using Teacher Feedback to Enhance Student Learning.

Published in:

Teaching Exceptional Children, 2004, v. 36, n. 6, p. 64, doi. 10.1177/004005990403600608

By:

Konold, Kathryn E.;
Miller, Susan P.;
Konold, Kyle B.

Publication type:

Article

Effects of serpentine soil factors on Virginia pine (Pinus virginiana) seedlings.

Published in:

Tree Physiology, 2000, v. 20, n. 16, p. 1129, doi. 10.1093/treephys/20.16.1129

By:

Miller, Susan P.;
Cumming, Jonathan R.

Publication type:

Article

N-terminal constraint activates the catalytic subunit of the DNA-dependent protein kinase in the absence of DNA or Ku.

Published in:

Nucleic Acids Research, 2012, v. 40, n. 7, p. 2964, doi. 10.1093/nar/gkr1211

By:

Meek, Katheryn;
Lees-Miller, Susan P.;
Modesti, Mauro

Publication type:

Article

XRCC4's interaction with XLF is required for coding (but not signal) end joining.

Published in:

Nucleic Acids Research, 2012, v. 40, n. 4, p. 1684, doi. 10.1093/nar/gkr1315

By:

Roy, Sunetra;
Andres, Sara N.;
Vergnes, Alexandra;
Neal, Jessica A.;
Xu, Yao;
Yu, Yaping;
Lees-Miller, Susan P.;
Junop, Murray;
Modesti, Mauro;
Meek, Katheryn

Publication type:

Article

Phosphorylation of polynucleotide kinase/ phosphatase by DNA-dependent protein kinase and ataxia-telangiectasia mutated regulates its association with sites of DNA damage.

Published in:

Nucleic Acids Research, 2011, v. 39, n. 21, p. 9224, doi. 10.1093/nar/gkr647

By:

Zolner, Angela E.;
Abdou, Ismail;
Ye, Ruiqiong;
Mani, Rajam S.;
Fanta, Mesfin;
Yu, Yaping;
Douglas, Pauline;
Tahbaz, Nasser;
Fang, Shujuan;
Dobbs, Tracey;
Wang, Chen;
Morrice, Nick;
Hendzel, Michael J.;
Weinfeld, Michael;
Lees-Miller, Susan P.

Publication type:

Article

The human telomerase RNA component, hTR, activates the DNA-dependent protein kinase to phosphorylate heterogeneous nuclear ribonucleoprotein A1.

Published in:

Nucleic Acids Research, 2009, v. 37, n. 18, p. 6105, doi. 10.1093/nar/gkp636

By:

Ting, Nicholas S. Y.;
Pohorelic, Brant;
Yu, Yaping;
Lees-Miller, Susan P.;
Beattie, Tara L.

Publication type:

Article

Requirement for XLF/Cernunnos in alignment-based gap filling by DNA polymerases λ and μ for nonhomologous end joining in human whole-cell extracts.

Published in:

Nucleic Acids Research, 2009, v. 37, n. 12, p. 4055, doi. 10.1093/nar/gkp283

By:

Akopiants, Konstantin;
Zhou, Rui-Zhe;
Mohapatra, Susovan;
Valerie, Kristoffer;
Lees-Miller, Susan P.;
Lee, Kyung-Jong;
Chen, David J.;
Revy, Patrick;
de Villartay, Jean-Pierre;
Povirk, Lawrence F.

Publication type:

Article

Phosphorylation in the serine/threonine 2609–2647 cluster promotes but is not essential for DNA-dependent protein kinase-mediated nonhomologous end joining in human whole-cell extracts.

Published in:

Nucleic Acids Research, 2007, v. 35, n. 12, p. 3869, doi. 10.1093/nar/gkm339

By:

Povirk, Lawrence F.;
Zhou, Rui-Zhe;
Ramsden, Dale A.;
Lees-Miller, Susan P.;
Valerie, Kristoffer

Publication type:

Article

Human Ku70/80 interacts directly with hTR, the RNA component of human telomerase.

Published in:

Nucleic Acids Research, 2005, v. 33, n. 7, p. 2090, doi. 10.1093/nar/gki342

By:

Ting, Nicholas S. Y.;
Yu, Yaping;
Pohorelic, Brant;
Lees-Miller, Susan P.;
Beattie, Tara L.

Publication type:

Article

Autophosphorylation-dependent remodeling of the DNA-dependent protein kinase catalytic subunit regulates ligation of DNA ends.

Published in:

Nucleic Acids Research, 2004, v. 32, n. 14, p. 4351, doi. 10.1093/nar/gkh761

By:

Block, Wesley D.;
Yu, Yaping;
Merkle, Dennis;
Gifford, Jessica L.;
Ding, Qi;
Meek, Katheryn;
Lees-Miller, Susan P.

Publication type:

Article

Selective inhibition of the DNA‐dependent protein kinase (DNA‐PK) by the radiosensitizing agent caffeine.

Published in:

Nucleic Acids Research, 2004, v. 32, n. 6, p. 1967, doi. 10.1093/nar/gkh508

By:

Block, Wesley D.;
Merkle, Dennis;
Meek, Katheryn;
Lees‐Miller, Susan P.

Publication type:

Article

Phosphatidyl inositol 3‐kinase‐like serine/threonine protein kinases (PIKKs) are required for DNA damage‐induced phosphorylation of the 32 kDa subunit of replication protein A at threonine 21.

Published in:

Nucleic Acids Research, 2004, v. 32, n. 3, p. 997, doi. 10.1093/nar/gkh265

By:

Block, Wesley D.;
Yu, Yaping;
Lees‐Miller, Susan P.

Publication type:

Article

Polo-like kinase 1 (PLK1) and protein phosphatase 6 (PP6) regulate DNA-dependent protein kinase catalytic subunit (DNA-PKcs) phosphorylation in mitosis.

Published in:

Bioscience Reports, 2014, v. 34, n. 3, p. 257, doi. 10.1042/BSR20140051

By:

DOUGLAS, Pauline;
Ruiqiong YE;
TRINKLE-MULCAHY, Laura;
NEAL, Jessica A.;
De WEVER, Veerle;
MORRICE, Nick A.;
MEEK, Katheryn;
LEES-MILLER, Susan P.

Publication type:

Article

ATM associates with and phosphorylates p53: mapping the region of interaction.

Published in:

Nature Genetics, 1998, v. 20, n. 4, p. 398, doi. 10.1038/3882

By:

Khanna, Kum Kum;
Keating, Katherine E.;
Kozlov, Sergei;
Scott, Shaun;
Gatei, Magtouf;
Hobson, Karen;
Taya, Yoichi;
Gabrielli, Brian;
Chan, Doug;
Lees-Miller, Susan P.;
Lavin, Martin F.

Publication type:

Article

DNA Double Strand Break Repair in Mitosis Is Suppressed by Phosphorylation of XRCC4.

Published in:

PLoS Genetics, 2014, v. 10, n. 8, p. 1, doi. 10.1371/journal.pgen.1004598

By:

Lees-Miller, Susan P.

Publication type:

Article

Nocodazole-Induced Expression and Phosphorylation of Anillin and Other Mitotic Proteins Are Decreased in DNA-Dependent Protein Kinase Catalytic Subunit-Deficient Cells and Rescued by Inhibition of the Anaphase-Promoting Complex/Cyclosome with proTAME but Not Apcin

Published in:

Molecular & Cellular Biology, 2020, v. 40, n. 13, p. 1, doi. 10.1128/MCB.00191-19

By:

Douglas, Pauline;
Ruiqiong Ye;
Radhamani, Suraj;
Cobban, Alexander;
Jenkins, Nicole P.;
Bartlett, Edward;
Roveredo, Jonathan;
Kettenbach, Arminja N.;
Lees-Miller, Susan P.

Publication type:

Article

Comparing ERCC1 protein expression, mRNA levels, and genotype in squamous cell carcinomas of the head and neck treated with concurrent chemoradiation stratified by HPV status.

Published in:

Head & Neck, 2012, v. 34, n. 6, p. 785, doi. 10.1002/hed.21817

By:

Hao, Desirée;
Lau, Harold Y.;
Eliasziw, Misha;
Box, Alan;
Diaz, Román;
Klimowicz, Alexander C.;
Shin, Brian;
Lees-Miller, Susan P.;
Magliocco, Anthony M.

Publication type:

Article

Prognostic significance of p16 in locally advanced squamous cell carcinoma of the head and neck treated with concurrent cisplatin and radiotherapy.

Published in:

Head & Neck, 2011, v. 33, n. 2, p. 251, doi. 10.1002/hed.21439

By:

Lau, Harold Y.;
Brar, Sony;
Klimowicz, Alexander C.;
Petrillo, Stephanie K.;
Hao, Desirée;
Brockton, Nigel T.;
Kong, Christina S.;
Lees-Miller, Susan P.;
Magliocco, Anthony M.

Publication type:

Article

DNA end sequestration by DNA-dependent protein kinase and end joining of sterically constrained substrates in whole-cell extracts.

Published in:

Environmental & Molecular Mutagenesis, 2003, v. 42, n. 4, p. 279

By:

Jae Wan Lee;
Kedar V. Inamdar;
Michele F. Hannah;
Susan P. Lees-Miller;
Lawrence F. Povirk

Publication type:

Article

The DNA-dependent protein kinase: the director at the end.

Published in:

Immunological Reviews, 2004, v. 200, n. 1, p. 132, doi. 10.1111/j.0105-2896.2004.00162.x

By:

Meek, Katheryn;
Gupta, Shikha;
Ramsden, Dale A.;
Lees-Miller, Susan P.

Publication type:

Article

Integrating Soil Ecological Knowledge into Restoration Management.

Published in:

Restoration Ecology, 2008, v. 16, n. 4, p. 608, doi. 10.1111/j.1526-100X.2008.00477.x

By:

Heneghan, Liam;
Miller, Susan P.;
Baer, Sara;
Callaham Jr., Mac A.;
Montgomery, James;
Pavao-Zuckerman, Mitchell;
Rhoades, Charles C.;
Richardson, Sarah

Publication type:

Article

Arbuscular mycorrhizal colonization of semi-aquatic grasses along a wide hydrologic gradient.

Published in:

New Phytologist, 2000, v. 145, n. 1, p. 145, doi. 10.1046/j.1469-8137.2000.00566.x

By:

Miller, Susan P.

Publication type:

Article

Author Correction: Automating data analysis for hydrogen/deuterium exchange mass spectrometry using data-independent acquisition methodology.

Published in:

2024

By:

Filandr, Frantisek;
Sarpe, Vladimir;
Raval, Shaunak;
Crowder, D. Alex;
Khan, Morgan F.;
Douglas, Pauline;
Coales, Stephen;
Viner, Rosa;
Syed, Aleem;
Tainer, John A.;
Lees-Miller, Susan P.;
Schriemer, David C.

Publication type:

Correction Notice

Automating data analysis for hydrogen/deuterium exchange mass spectrometry using data-independent acquisition methodology.

Published in:

Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-46610-3

By:

Filandr, Frantisek;
Sarpe, Vladimir;
Raval, Shaunak;
Crowder, D. Alex;
Khan, Morgan F.;
Douglas, Pauline;
Coales, Stephen;
Viner, Rosa;
Syed, Aleem;
Tainer, John A.;
Lees-Miller, Susan P.;
Schriemer, David C.

Publication type:

Article

ATM-Deficient Cancers Provide New Opportunities for Precision Oncology.

Published in:

Cancers, 2020, v. 12, n. 3, p. 687, doi. 10.3390/cancers12030687

By:

Jette, Nicholas R.;
Kumar, Mehul;
Radhamani, Suraj;
Arthur, Greydon;
Goutam, Siddhartha;
Yip, Steven;
Kolinsky, Michael;
Williams, Gareth J.;
Bose, Pinaki;
Lees-Miller, Susan P.

Publication type:

Article

Enhanced cytotoxicity of PARP inhibition in mantle cell lymphoma harbouring mutations in both ATM and p53.

Published in:

EMBO Molecular Medicine, 2012, v. 4, n. 6, p. 515, doi. 10.1002/emmm.201200229

By:

Williamson, Chris T.;
Kubota, Eiji;
Hamill, Jeffrey D.;
Klimowicz, Alexander;
Ye, Ruiqiong;
Muzik, Huong;
Dean, Michelle;
Tu, LiRen;
Gilley, David;
Magliocco, Anthony M.;
McKay, Bruce C.;
Bebb, D. Gwyn;
Lees-Miller, Susan P.

Publication type:

Article

Choreographing the DNA damage response.

Published in:

Cell Cycle, 2010, v. 9, n. 7, p. 1221, doi. 10.4161/cc.9.7.11321

By:

Douglas, Pauline;
Moorhead, Greg;
Xingzhi Xu;
Lees-Miller, Susan P.

Publication type:

Article

DNA double strand breaks: Not all foci are created equal.

Published in:

Cell Cycle, 2010, v. 9, n. 3, p. 442, doi. 10.4161/cc.9.3.10694

By:

Cobb, Jennifer A.;
Lees-Miller, Susan P.

Publication type:

Article

Phosphorylation of SAF-A/hnRNP-U Serine 59 by Polo-Like Kinase 1 Is Required for Mitosis.

Published in:

Molecular & Cellular Biology, 2015, v. 35, n. 15, p. 2699, doi. 10.1128/MCB.01312-14

By:

Douglas, Pauline;
Ruiqiong Ye;
Morrice, Nicholas;
Britton, Sébastien;
Trinkle-Mulcahy, Laura;
Lees-Miller, Susan P.

Publication type:

Article

Unraveling the Complexities of DNA-Dependent Protein Kinase Autophosphorylation.

Published in:

Molecular & Cellular Biology, 2014, v. 34, n. 12, p. 2162, doi. 10.1128/MCB.01554-13

By:

Neal, Jessica A.;
Sugiman-Marangos, Seiji;
VanderVere-Carozza, Pamela;
Wagner, Mike;
Turchi, John;
Lees-Miller, Susan P.;
Junop, Murray S.;
Meek, Katheryn

Publication type:

Article

Inhibition of Homologous Recombination by DNA-Dependent Protein Kinase Requires Kinase Activity, Is Titratable, and Is Modulated by Autophosphorylation.

Published in:

Molecular & Cellular Biology, 2011, v. 31, n. 8, p. 1719, doi. 10.1128/MCB.01298-10

By:

Neal, Jessica A.;
Dang, Van;
Douglas, Pauline;
Wold, Marc S.;
Lees-Miller, Susan P.;
Meek, Katheryn

Publication type:

Article

Protein Phosphatase 6 Interacts with the DNA-Dependent Protein Kinase Catalytic Subunit and Dephosphorylates γ-H2AX.

Published in:

Molecular & Cellular Biology, 2010, v. 30, n. 6, p. 6, doi. 10.1128/MCB.00741-09

By:

Douglas, Pauline;
Jianing Zhong;
Ruiqiong Ye;
Moorhead, Greg B. G.;
Xingzhi Xu;
Lees-Miller, Susan P.

Publication type:

Article

trans Autophosphorylation at DNA-Dependent Protein Kinase's Two Major Autophosphorylation Site Clusters Facilitates End Processing but Not End Joining.

Published in:

Molecular & Cellular Biology, 2007, v. 27, n. 10, p. 27, doi. 10.1128/MCB.02366-06

By:

Meek, Katheryn;
Douglas, Pauline;
Xiaoping Cui;
Qi Ding;
Lees-Miller, Susan P.

Publication type:

Article

The DNA-Dependent Protein Kinase Catalytic Subunit Is Phosphorylated In Vivo on Threonine 3950, a Highly Conserved Amino Acid in the Protein Kinase Domain.

Published in:

Molecular & Cellular Biology, 2007, v. 27, n. 5, p. 4, doi. 10.1128/MCB.01962-06

By:

Douglas, Pauline;
Xiaoping Cui;
Block, Wesley D.;
Yaping Yu;
Gupta, Shikha;
Qi Ding;
Ruiqiong Ye;
Morrice, Nick;
Lees-Miller, Susan P.;
Meek, Katheryn

Publication type:

Article

Comparing Web-based to Traditional Instruction for Teaching Special Education Content.

Published in:

Teacher Education & Special Education, 2007, v. 30, n. 1, p. 34, doi. 10.1177/088840640703000104

By:

Neal, Kelly O.;
Jones, W. Paul;
Miller, Susan P.;
Campbell, Pamela;
Pierce, Thomas

Publication type:

Article

DEVELOPING ADDITION WITH REGROUPING COMPETENCE AMONG SECOND GRADE STUDENTS WITH MATHEMATICS DIFFICULTIES.

Published in:

Investigations in Mathematics Learning, 2011, v. 4, n. 1, p. 24, doi. 10.1080/24727466.2011.11790308

By:

Miller, Susan P.;
Kaffar, Bradley j.

Publication type:

Article

XRCC4 and XLF form long helical protein filaments suitable for DNA end protection and alignment to facilitate DNA double strand break repair<sup>1</sup>.

Published in:

Biochemistry & Cell Biology, 2013, v. 91, n. 1, p. 31, doi. 10.1139/bcb-2012-0058

By:

Mahaney, Brandi L.;
Hammel, Michal;
Meek, Katheryn;
Tainer, John A.;
Lees-Miller, Susan P.

Publication type:

Article

Mechanism of efficient double-strand break repair by a long non-coding RNA.

Published in:

Nucleic Acids Research, 2020, v. 48, n. 19, p. 10953, doi. 10.1093/nar/gkaa784

By:

Thapar, Roopa;
Wang, Jing L;
Hammel, Michal;
Ye, Ruiqiong;
Liang, Ke;
Sun, Chengcao;
Hnizda, Ales;
Liang, Shikang;
Maw, Su S;
Lee, Linda;
Villarreal, Heather;
Forrester, Isaac;
Fang, Shujuan;
Tsai, Miaw-Sheue;
Blundell, Tom L;
Davis, Anthony J;
Lin, Chunru;
Lees-Miller, Susan P;
Strick, Terence R;
Tainer, John A

Publication type:

Article

Structural and functional characterization of the PNKP-XRCC4-LigIV DNA repair complex.

Published in:

Nucleic Acids Research, 2017, v. 45, n. 10, p. 6238, doi. 10.1093/nar/gkx275

By:

Aceytuno, R. Daniel;
Piett, Cortt G.;
Havali-Shahriari, Zahra;
Edwards, Ross A.;
Rey, Martial;
Ruiqiong Ye;
Javed, Fatima;
Shujuan Fang;
Mani, Rajam;
Weinfeld, Michael;
Hammel, Michal;
Tainer, John A.;
Schriemer, David C.;
Lees-Miller, Susan P.;
Glover, J. N. Mark

Publication type:

Article

Low ATM protein expression in malignant tumor as well as cancer-associated stroma are independent prognostic factors in a retrospective study of early-stage hormone-negative breast cancer.

Published in:

Breast Cancer Research, 2015, v. 17, n. 1, p. 1, doi. 10.1186/s13058-015-0575-2

By:

Xiaolan Feng;
Haocheng Li;
Dean, Michelle;
Wilson, Holly E.;
Kornaga, Elizabeth;
Enwere, Emeka K.;
Tang, Patricia;
Paterson, Alexander;
Lees-Miller, Susan P.;
Magliocco, Anthony M.;
Bebb, Gwyn

Publication type:

Article

DNA-PK autophosphorylation facilitates Artemis endonuclease activity.

Published in:

EMBO Journal, 2006, v. 25, n. 16, p. 3880, doi. 10.1038/sj.emboj.7601255

By:

Goodarzi, Aaron A.;
Yaping Yu;
Riballo, Enriqueta;
Douglas, Pauline;
Walker, Sarah A.;
Ruiqiong Ye;
Härer, Christine;
Marchetti, Caterina;
Morrice, Nick;
Jeggo, Penny A.;
Lees-Miller, Susan P.

Publication type:

Article

Autophosphorylation of ataxia-telangiectasia mutated is regulated by protein phosphatase 2A.

Published in:

EMBO Journal, 2004, v. 23, n. 22, p. 4451, doi. 10.1038/sj.emboj.7600455

By:

Goodarzi, Aaron A;
Jonnalagadda, Jyoti C;
Douglas, Pauline;
Young, David;
Ye, Ruiqiong;
Moorhead, Greg B. G.;
Lees-Miller, Susan P.;
Khanna, Kum Kum

Publication type:

Article

Structure of the RPA trimerization core and its role in the multistep DNA-binding mechanism of RPA.

Published in:

EMBO Journal, 2002, v. 21, n. 7, p. 1855, doi. 10.1093/emboj/21.7.1855

By:

Bochkareva, Elena;
Korolev, Sergey;
Lees-Miller, Susan P.;
Bochkarev, Alexey

Publication type:

Article