Works matching AU Milde, Till

Results: 71
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    Pediatric Targeted Therapy: Clinical Feasibility of Personalized Diagnostics in Children with Relapsed and Progressive Tumors.

    Published in:
    Brain Pathology, 2016, v. 26, n. 4, p. 506, doi. 10.1111/bpa.12326
    By:
    • Selt, Florian;
    • Deiß, Alica;
    • Korshunov, Andrey;
    • Capper, David;
    • Witt, Hendrik;
    • van Tilburg, Cornelis M.;
    • Jones, David T. W.;
    • Witt, Ruth;
    • Sahm, Felix;
    • Reuss, David;
    • Kölsche, Christian;
    • Ecker, Jonas;
    • Oehme, Ina;
    • Hielscher, Thomas;
    • von Deimling, Andreas;
    • Kulozik, Andreas E.;
    • Pfister, Stefan M.;
    • Witt, Olaf;
    • Milde, Till
    Publication type:
    Article
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    Emerging Insights into the Ependymoma Epigenome.

    Published in:
    Brain Pathology, 2013, v. 23, n. 2, p. 206, doi. 10.1111/bpa.12020
    By:
    • Mack, Stephen C.;
    • Witt, Hendrik;
    • Wang, Xin;
    • Milde, Till;
    • Yao, Yuan;
    • Bertrand, Kelsey C.;
    • Korshunov, Andrey;
    • Pfister, Stefan M.;
    • Taylor, Michael D.
    Publication type:
    Article
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    Nestin Expression Identifies Ependymoma Patients with Poor Outcome.

    Published in:
    Brain Pathology, 2012, v. 22, n. 6, p. 848, doi. 10.1111/j.1750-3639.2012.00600.x
    By:
    • Milde, Till;
    • Hielscher, Thomas;
    • Witt, Hendrik;
    • Kool, Marcel;
    • Mack, Stephen C.;
    • Deubzer, Hedwig E.;
    • Oehme, Ina;
    • Lodrini, Marco;
    • Benner, Axel;
    • Taylor, Michael D.;
    • von Deimling, Andreas;
    • Kulozik, Andreas E.;
    • Pfister, Stefan M.;
    • Witt, Olaf;
    • Korshunov, Andrey
    Publication type:
    Article
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    MicroRNA-182 promotes leptomeningeal spread of non-sonic hedgehog-medulloblastoma.

    Published in:
    Acta Neuropathologica, 2012, v. 123, n. 4, p. 529, doi. 10.1007/s00401-011-0924-x
    By:
    • Bai, Alfa;
    • Milde, Till;
    • Remke, Marc;
    • Rolli, Claudio;
    • Hielscher, Thomas;
    • Cho, Yoon-Jae;
    • Kool, Marcel;
    • Northcott, Paul;
    • Jugold, Manfred;
    • Bazhin, Alexandr;
    • Eichmüller, Stefan;
    • Kulozik, Andreas;
    • Pscherer, Armin;
    • Benner, Axel;
    • Taylor, Michael;
    • Pomeroy, Scott;
    • Kemkemer, Ralf;
    • Witt, Olaf;
    • Korshunov, Andrey;
    • Lichter, Peter
    Publication type:
    Article
    9

    A novel human high-risk ependymoma stem cell model reveals the differentiation-inducing potential of the histone deacetylase inhibitor Vorinostat.

    Published in:
    Acta Neuropathologica, 2011, v. 122, n. 5, p. 637, doi. 10.1007/s00401-011-0866-3
    By:
    • Milde, Till;
    • Kleber, Susanne;
    • Korshunov, Andrey;
    • Witt, Hendrik;
    • Hielscher, Thomas;
    • Koch, Philipp;
    • Kopp, Hans-Georg;
    • Jugold, Manfred;
    • Deubzer, Hedwig;
    • Oehme, Ina;
    • Lodrini, Marco;
    • Gröne, Hermann-Josef;
    • Benner, Axel;
    • Brüstle, Oliver;
    • Gilbertson, Richard;
    • Deimling, Andreas;
    • Kulozik, Andreas;
    • Pfister, Stefan;
    • Martin-Villalba, Ana;
    • Witt, Olaf
    Publication type:
    Article
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    Pleomorphic xanthoastrocytoma is a heterogeneous entity with pTERT mutations prognosticating shorter survival.

    Published in:
    Acta Neuropathologica Communications, 2022, v. 10, n. 1, p. 1, doi. 10.1186/s40478-021-01308-1
    By:
    • Ebrahimi, Azadeh;
    • Korshunov, Andrey;
    • Reifenberger, Guido;
    • Capper, David;
    • Felsberg, Joerg;
    • Trisolini, Elena;
    • Pollo, Bianca;
    • Calatozzolo, Chiara;
    • Prinz, Marco;
    • Staszewski, Ori;
    • Schweizer, Leonille;
    • Schittenhelm, Jens;
    • Harter, Patrick N.;
    • Paulus, Werner;
    • Thomas, Christian;
    • Kohlhof-Meinecke, Patricia;
    • Seiz-Rosenhagen, Marcel;
    • Milde, Till;
    • Casalini, Belén M.;
    • Suwala, Abigail
    Publication type:
    Article
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    Biglycan-driven risk stratification in ZFTA-RELA fusion supratentorial ependymomas through transcriptome profiling.

    Published in:
    Acta Neuropathologica Communications, 2025, v. 13, n. 1, p. 1, doi. 10.1186/s40478-024-01921-w
    By:
    • Okonechnikov, Konstantin;
    • Ghasemi, David R.;
    • Schrimpf, Daniel;
    • Tonn, Svenja;
    • Mynarek, Martin;
    • Koster, Jan;
    • Milde, Till;
    • Zheng, Tuyu;
    • Sievers, Philipp;
    • Sahm, Felix;
    • Jones, David T.W.;
    • von Deimling, Andreas;
    • Pfister, Stefan M.;
    • Kool, Marcel;
    • Pajtler, Kristian W.;
    • Korshunov, Andrey
    Publication type:
    Article
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    Biglycan-driven risk stratification in ZFTA-RELA fusion supratentorial ependymomas through transcriptome profiling.

    Published in:
    Acta Neuropathologica Communications, 2025, v. 12, n. 1, p. 1, doi. 10.1186/s40478-024-01921-w
    By:
    • Okonechnikov, Konstantin;
    • Ghasemi, David R.;
    • Schrimpf, Daniel;
    • Tonn, Svenja;
    • Mynarek, Martin;
    • Koster, Jan;
    • Milde, Till;
    • Zheng, Tuyu;
    • Sievers, Philipp;
    • Sahm, Felix;
    • Jones, David T.W.;
    • von Deimling, Andreas;
    • Pfister, Stefan M.;
    • Kool, Marcel;
    • Pajtler, Kristian W.;
    • Korshunov, Andrey
    Publication type:
    Article
    17

    3D genome mapping identifies subgroup-specific chromosome conformations and tumor-dependency genes in ependymoma.

    Published in:
    Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-38044-0
    By:
    • Okonechnikov, Konstantin;
    • Camgöz, Aylin;
    • Chapman, Owen;
    • Wani, Sameena;
    • Park, Donglim Esther;
    • Hübner, Jens-Martin;
    • Chakraborty, Abhijit;
    • Pagadala, Meghana;
    • Bump, Rosalind;
    • Chandran, Sahaana;
    • Kraft, Katerina;
    • Acuna-Hidalgo, Rocio;
    • Reid, Derek;
    • Sikkink, Kristin;
    • Mauermann, Monika;
    • Juarez, Edwin F.;
    • Jenseit, Anne;
    • Robinson, James T.;
    • Pajtler, Kristian W.;
    • Milde, Till
    Publication type:
    Article
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    Group-specific cellular metabolism in Medulloblastoma.

    Published in:
    Journal of Translational Medicine, 2023, v. 21, n. 1, p. 1, doi. 10.1186/s12967-023-04211-6
    By:
    • Funke, Viktoria L. E.;
    • Walter, Carolin;
    • Melcher, Viktoria;
    • Wei, Lanying;
    • Sandmann, Sarah;
    • Hotfilder, Marc;
    • Varghese, Julian;
    • Jäger, Natalie;
    • Kool, Marcel;
    • Jones, David T. W.;
    • Pfister, Stefan M.;
    • Milde, Till;
    • Mynarek, Martin;
    • Rutkowski, Stefan;
    • Seggewiss, Jochen;
    • Jeising, Daniela;
    • de Faria, Flavia W.;
    • Marquardt, Thorsten;
    • Albert, Thomas K.;
    • Schüller, Ulrich
    Publication type:
    Article
    20

    Retinal angiogenesis suppression through small molecule activation of p53.

    Published in:
    Journal of Clinical Investigation, 2013, v. 123, n. 10, p. 4170, doi. 10.1172/JCI67315
    By:
    • Chavala, Sai H.;
    • Younghee Kim;
    • Tudisco, Laura;
    • Cicatiello, Valeria;
    • Milde, Till;
    • Kerur, Nagaraj;
    • Claros, Nidia;
    • Yanni, Susan;
    • Guaiquil, Victor H.;
    • Hauswirth, William W.;
    • Penn, John S.;
    • Rafii, Shahin;
    • De Falco, Sandro;
    • Lee, Thomas C.;
    • Ambati, Jayakrishna
    Publication type:
    Article
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    CD133 expression is not restricted to stem cells, and both CD133+ and CD133- metastatic colon cancer cells initiate tumors.

    Published in:
    2008
    By:
    • Shmelkov, Sergey V.;
    • Butler, Jason M.;
    • Hooper, Andrea T.;
    • Hormigo, Adilia;
    • Kushner, Jared;
    • Milde, Till;
    • St. Clair, Ryan;
    • Baljevic, Muhamed;
    • White, Ian;
    • Jin, David K.;
    • Chadburn, Amy;
    • Murphy, Andrew J.;
    • Valenzuela, David M.;
    • Gale, Nicholas W.;
    • Thurston, Gavin;
    • Yancopoulos, George D.;
    • D'Angelica, Michael;
    • Kemeny, Nancy;
    • Lyden, David;
    • Rafii, Shahin
    Publication type:
    journal article
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    Targeting class I histone deacetylase 2 in MYC amplified group 3 medulloblastoma.

    Published in:
    Acta Neuropathologica Communications, 2015, v. 3, n. 1, p. 121, doi. 10.1186/s40478-015-0201-7
    By:
    • Ecker, Jonas;
    • Oehme, Ina;
    • Mazitschek, Ralph;
    • Korshunov, Andrey;
    • Kool, Marcel;
    • Hielscher, Thomas;
    • Kiss, Judit;
    • Selt, Florian;
    • Konrad, Carina;
    • Lodrini, Marco;
    • Deubzer, Hedwig E.;
    • von Deimling, Andreas;
    • Kulozik, Andreas E.;
    • Pfister, Stefan M.;
    • Witt, Olaf;
    • Milde, Till
    Publication type:
    Article
    25

    Soft Tissue Undifferentiated Sarcoma Carrying a Novel Onecut1::Nutm1 Fusion.

    Published in:
    Pediatric Blood & Cancer, 2025, v. 72, n. 1, p. 1, doi. 10.1002/pbc.31427
    By:
    • Filippidou, Maria;
    • Glentis, Stavros;
    • Rigatou, Efthymia;
    • Sievers, Philipp;
    • Selt, Florian;
    • Dimitriadis, Efthymios;
    • Perari, Panagiota;
    • Binenbaum, Ilona;
    • Avgerinou, Georgia;
    • van Tilburg, Cornelis M.;
    • Jones, David T. W.;
    • Sahm, Felix;
    • Milde, Till;
    • Witt, Olaf;
    • Pfister, Stefan M.;
    • Grünewald, Thomas G. P.;
    • Stefanaki, Kalliopi;
    • Kattamis, Antonis
    Publication type:
    Article
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    Systemic chemotherapy of pediatric recurrent ependymomas: results from the German HIT-REZ studies.

    Published in:
    Journal of Neuro-Oncology, 2021, v. 155, n. 2, p. 193, doi. 10.1007/s11060-021-03867-8
    By:
    • Adolph, Jonas E.;
    • Fleischhack, Gudrun;
    • Gaab, Christine;
    • Mikasch, Ruth;
    • Mynarek, Martin;
    • Rutkowski, Stefan;
    • Schüller, Ulrich;
    • Pfister, Stefan M.;
    • Pajtler, Kristian W.;
    • Milde, Till;
    • Witt, Olaf;
    • Bison, Brigitte;
    • Warmuth-Metz, Monika;
    • Kortmann, Rolf-Dieter;
    • Dietzsch, Stefan;
    • Pietsch, Torsten;
    • Timmermann, Beate;
    • Tippelt, Stephan
    Publication type:
    Article
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    Response to trametinib treatment in progressive pediatric low-grade glioma patients.

    Published in:
    Journal of Neuro-Oncology, 2020, v. 149, n. 3, p. 499, doi. 10.1007/s11060-020-03640-3
    By:
    • Selt, Florian;
    • van Tilburg, Cornelis M.;
    • Bison, Brigitte;
    • Sievers, Philipp;
    • Harting, Inga;
    • Ecker, Jonas;
    • Pajtler, Kristian W.;
    • Sahm, Felix;
    • Bahr, Annabelle;
    • Simon, Michèle;
    • Jones, David T. W.;
    • Well, Lennart;
    • Mautner, Victor-Felix;
    • Capper, David;
    • Hernáiz Driever, Pablo;
    • Gnekow, Astrid;
    • Pfister, Stefan M.;
    • Witt, Olaf;
    • Milde, Till
    Publication type:
    Article
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    Radiotherapy for Recurrent Medulloblastoma in Children and Adolescents: Survival after Re-Irradiation and First-Time Irradiation.

    Published in:
    Cancers, 2024, v. 16, n. 11, p. 1955, doi. 10.3390/cancers16111955
    By:
    • Adolph, Jonas E.;
    • Fleischhack, Gudrun;
    • Tschirner, Sebastian;
    • Rink, Lydia;
    • Dittes, Christine;
    • Mikasch, Ruth;
    • Dammann, Philipp;
    • Mynarek, Martin;
    • Obrecht-Sturm, Denise;
    • Rutkowski, Stefan;
    • Bison, Brigitte;
    • Warmuth-Metz, Monika;
    • Pietsch, Torsten;
    • Pfister, Stefan M.;
    • Pajtler, Kristian W.;
    • Milde, Till;
    • Kortmann, Rolf-Dieter;
    • Dietzsch, Stefan;
    • Timmermann, Beate;
    • Tippelt, Stephan
    Publication type:
    Article
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    Infants and Newborns with Atypical Teratoid Rhabdoid Tumors (ATRT) and Extracranial Malignant Rhabdoid Tumors (eMRT) in the EU-RHAB Registry: A Unique and Challenging Population.

    Published in:
    Cancers, 2022, v. 14, n. 9, p. N.PAG, doi. 10.3390/cancers14092185
    By:
    • Nemes, Karolina;
    • Johann, Pascal D.;
    • Steinbügl, Mona;
    • Gruhle, Miriam;
    • Bens, Susanne;
    • Kachanov, Denis;
    • Teleshova, Margarita;
    • Hauser, Peter;
    • Simon, Thorsten;
    • Tippelt, Stephan;
    • Eberl, Wolfgang;
    • Chada, Martin;
    • Lopez, Vicente Santa-Maria;
    • Grigull, Lorenz;
    • Hernáiz-Driever, Pablo;
    • Eyrich, Matthias;
    • Pears, Jane;
    • Milde, Till;
    • Reinhard, Harald;
    • Leipold, Alfred
    Publication type:
    Article
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    Combining APR-246 and HDAC-Inhibitors: A Novel Targeted Treatment Option for Neuroblastoma.

    Published in:
    Cancers, 2021, v. 13, n. 17, p. 4476, doi. 10.3390/cancers13174476
    By:
    • Müller, Michael;
    • Rösch, Lisa;
    • Najafi, Sara;
    • Gatzweiler, Charlotte;
    • Ridinger, Johannes;
    • Gerloff, Xenia F.;
    • Jones, David T. W.;
    • Baßler, Jochen;
    • Kreth, Sina;
    • Stainczyk, Sabine;
    • Frese, Karen;
    • Meder, Benjamin;
    • Westermann, Frank;
    • Milde, Till;
    • Peterziel, Heike;
    • Witt, Olaf;
    • Oehme, Ina
    Publication type:
    Article
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    A synergistic interaction between HDAC‐ and PARP inhibitors in childhood tumors with chromothripsis.

    Published in:
    International Journal of Cancer, 2022, v. 151, n. 4, p. 590, doi. 10.1002/ijc.34027
    By:
    • Khalid, Umar;
    • Simovic, Milena;
    • Hammann, Linda A.;
    • Iskar, Murat;
    • Wong, John K. L.;
    • Kumar, Rithu;
    • Jugold, Manfred;
    • Sill, Martin;
    • Bolkestein, Michiel;
    • Kolb, Thorsten;
    • Hergt, Michaela;
    • Devens, Frauke;
    • Ecker, Jonas;
    • Kool, Marcel;
    • Milde, Till;
    • Westermann, Frank;
    • Benner, Axel;
    • Lewis, Joe;
    • Dietrich, Sascha;
    • Pfister, Stefan M.
    Publication type:
    Article
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    Cerebrospinal Fluid Penetration and Combination Therapy of Entrectinib for Disseminated ROS1/NTRK-Fusion Positive Pediatric High-Grade Glioma.

    Published in:
    Journal of Personalized Medicine, 2020, v. 10, n. 4, p. 1, doi. 10.3390/jpm10040290
    By:
    • Mayr, Lisa;
    • Guntner, Armin S.;
    • Madlener, Sibylle;
    • Schmook, Maria T.;
    • Peyrl, Andreas;
    • Azizi, Amedeo A.;
    • Dieckmann, Karin;
    • Reisinger, Dominik;
    • Stepien, Natalia M.;
    • Schramm, Kathrin;
    • Laemmerer, Anna;
    • Jones, David T. W.;
    • Ecker, Jonas;
    • Sahm, Felix;
    • Milde, Till;
    • Pajtler, Kristian W.;
    • Blattner-Johnson, Mirjam;
    • Strbac, Miroslav;
    • Dorfer, Christian;
    • Czech, Thomas
    Publication type:
    Article
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    Synergy of retinoic acid and BH3 mimetics in MYC(N)-driven embryonal nervous system tumours.

    Published in:
    British Journal of Cancer, 2024, v. 131, n. 4, p. 763, doi. 10.1038/s41416-024-02740-5
    By:
    • Seiboldt, Till;
    • Zeiser, Constantia;
    • Nguyen, Duy;
    • Celikyürekli, Simay;
    • Herter, Sonja;
    • Najafi, Sara;
    • Stroh-Dege, Alexandra;
    • Meulenbroeks, Chris;
    • Mack, Norman;
    • Salem-Altintas, Rabia;
    • Westermann, Frank;
    • Schlesner, Matthias;
    • Milde, Till;
    • Kool, Marcel;
    • Holland-Letz, Tim;
    • Vogler, Meike;
    • Peterziel, Heike;
    • Witt, Olaf;
    • Oehme, Ina
    Publication type:
    Article
    43

    Mitochondrial DNA mutations in Medulloblastoma.

    Published in:
    Acta Neuropathologica Communications, 2023, v. 11, n. 1, p. 1, doi. 10.1186/s40478-023-01602-0
    By:
    • Funke, Viktoria L. E.;
    • Sandmann, Sarah;
    • Melcher, Viktoria;
    • Seggewiss, Jochen;
    • Horvath, Judit;
    • Jäger, Natalie;
    • Kool, Marcel;
    • Jones, David T. W.;
    • Pfister, Stefan M.;
    • Milde, Till;
    • Rutkowski, Stefan;
    • Mynarek, Martin;
    • Varghese, Julian;
    • Sträter, Ronald;
    • Rust, Stephan;
    • Seelhöfer, Anja;
    • Reunert, Janine;
    • Fiedler, Barbara;
    • Schüller, Ulrich;
    • Marquardt, Thorsten
    Publication type:
    Article
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    Constitutional variants in PTEN: a frequent finding in patients with papillary tumors of the pineal region subtype B (PTPR-B) associated with isolated loss of chromosome 10.

    Published in:
    2025
    By:
    • Hirsch, Steffen;
    • Rahmanzade, Ramin;
    • Grund, Kerstin;
    • Sutter, Christian;
    • Schramm, Kathrin;
    • Selt, Florian;
    • Ecker, Jonas;
    • Jones, Barbara C.;
    • Schrimpf, Daniel;
    • Demmert, Martin;
    • Guerreiro Stücklin, Ana S.;
    • Hernaiz Driever, Pablo;
    • Mezger, Markus;
    • Brecht, Ines;
    • Adib, Sasan D.;
    • Brummel, Bastian;
    • Sturm, Dominik;
    • Dikow, Nicola;
    • Hempel, Maja;
    • Milde, Till
    Publication type:
    Letter
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    Glioneuronal tumor with ATRX alteration, kinase fusion and anaplastic features (GTAKA): a molecularly distinct brain tumor type with recurrent NTRK gene fusions.

    Published in:
    Acta Neuropathologica, 2023, v. 145, n. 5, p. 667, doi. 10.1007/s00401-023-02558-0
    By:
    • Bogumil, Henri;
    • Sill, Martin;
    • Schrimpf, Daniel;
    • Ismer, Britta;
    • Blume, Christina;
    • Rahmanzade, Ramin;
    • Hinz, Felix;
    • Cherkezov, Asan;
    • Banan, Rouzbeh;
    • Friedel, Dennis;
    • Reuss, David E.;
    • Selt, Florian;
    • Ecker, Jonas;
    • Milde, Till;
    • Pajtler, Kristian W.;
    • Schittenhelm, Jens;
    • Hench, Jürgen;
    • Frank, Stephan;
    • Boldt, Henning B.;
    • Kristensen, Bjarne Winther
    Publication type:
    Article
    50

    GOPC:ROS1 and other ROS1 fusions represent a rare but recurrent drug target in a variety of glioma types.

    Published in:
    Acta Neuropathologica, 2021, v. 142, n. 6, p. 1065, doi. 10.1007/s00401-021-02369-1
    By:
    • Sievers, Philipp;
    • Stichel, Damian;
    • Sill, Martin;
    • Schrimpf, Daniel;
    • Sturm, Dominik;
    • Selt, Florian;
    • Ecker, Jonas;
    • Kazdal, Daniel;
    • Miele, Evelina;
    • Kranendonk, Mariëtte E. G.;
    • Tops, Bastiaan B. J.;
    • Kohlhof-Meinecke, Patricia;
    • Beschorner, Rudi;
    • Kramm, Christof M.;
    • Hasselblatt, Martin;
    • Reifenberger, Guido;
    • Capper, David;
    • Wesseling, Pieter;
    • Stenzinger, Albrecht;
    • Milde, Till
    Publication type:
    Article