Works by Middleton, Frank A.

Results: 60

Differential expression of miRNAs in acute myeloid leukemia quantified by Nextgen sequencing of whole blood samples.

Published in:

PLoS ONE, 2019, v. 14, n. 3, p. 1, doi. 10.1371/journal.pone.0213078

By:

Pandita, Aakriti;
Ramadas, Poornima;
Poudel, Aarati;
Saad, Nibal;
Anand, Ankit;
Basnet, Alina;
Wang, Dongliang;
Middleton, Frank;
Gilligan, Diana M.

Publication type:

Article

Comparison of serum and saliva miRNAs for identification and characterization of mTBI in adult mixed martial arts fighters.

Published in:

PLoS ONE, 2019, v. 14, n. 01, p. 1, doi. 10.1371/journal.pone.0207785

By:

LaRocca, Daria;
Barns, Sarah;
Hicks, Steven D.;
Brindle, Andrew;
Williams, Jeremy;
Uhlig, Richard;
Johnson, Paul;
Neville, Christopher;
Middleton, Frank A.

Publication type:

Article

Diurnal oscillations in human salivary microRNA and microbial transcription: Implications for human health and disease.

Published in:

PLoS ONE, 2018, v. 13, n. 7, p. 1, doi. 10.1371/journal.pone.0198288

By:

Hicks, Steven D.;
Khurana, Neil;
Williams, Jeremy;
Dowd Greene, Cindy;
Uhlig, Richard;
Middleton, Frank A.

Publication type:

Article

Environmental risk factors for attention-deficit hyperactivity disorder.

Published in:

Acta Paediatrica, 2007, v. 96, n. 9, p. 1269, doi. 10.1111/j.1651-2227.2007.00430.x

By:

Banerjee, Tania Das;
Middleton, Frank;
Faraone, Stephen V.

Publication type:

Article

Genome-wide copy number variation study associates metabotropic glutamate receptor gene networks with attention deficit hyperactivity disorder.

Published in:

Nature Genetics, 2012, v. 44, n. 1, p. 78, doi. 10.1038/ng.1013

By:

Elia, Josephine;
Glessner, Joseph T;
Wang, Kai;
Takahashi, Nagahide;
Shtir, Corina J;
Hadley, Dexter;
Sleiman, Patrick M A;
Zhang, Haitao;
Kim, Cecilia E;
Robison, Reid;
Lyon, Gholson J;
Flory, James H;
Bradfield, Jonathan P;
Imielinski, Marcin;
Hou, Cuiping;
Frackelton, Edward C;
Chiavacci, Rosetta M;
Sakurai, Takeshi;
Rabin, Cara;
Middleton, Frank A

Publication type:

Article

Thrombospondin-1 differentially regulates microRNAs in vascular smooth muscle cells.

Published in:

Molecular & Cellular Biochemistry, 2016, v. 412, n. 1/2, p. 111, doi. 10.1007/s11010-015-2614-9

By:

Maier, Kristopher;
Ruhle, Brian;
Stein, Jeffrey;
Gentile, Karen;
Middleton, Frank;
Gahtan, Vivian

Publication type:

Article

Dengue Virus Structural Proteins Are Expressed on the Surface of DENV-Infected Cells and Are a Target for Antibody-Dependent Cellular Phagocytosis.

Published in:

Open Forum Infectious Diseases, 2025, v. 12, n. 1, p. 1, doi. 10.1093/ofid/ofae720

By:

Waldran, Mitchell J;
Kurtz, Elizabeth A;
Gebo, Chad J;
Rooney, Timothy J;
Middleton, Frank A;
Roy, Nathan H;
Currier, Jeffrey R;
Waickman, Adam T

Publication type:

Article

A comparative review of microrNA expression Patterns in Autism spectrum Disorder.

Published in:

Frontiers in Psychiatry, 2016, v. 7, p. 1, doi. 10.3389/fpsyt.2016.00176

By:

Hicks, Steven D.;
Middleton, Frank A.

Publication type:

Article

Epstein–Barr Virus Genetic Variation in Lymphoblastoid Cell Lines Derived from Kenyan Pediatric Population.

Published in:

PLoS ONE, 2015, v. 10, n. 5, p. 1, doi. 10.1371/journal.pone.0125420

By:

Simbiri, Kenneth O.;
Smith, Nicholas A.;
Otieno, Richard;
Wohlford, Eric E. M.;
Daud, Ibrahim I.;
Odada, Sumba P.;
Middleton, Frank;
Rochford, Rosemary

Publication type:

Article

Crizotinib induces apoptosis and gene expression changes in ALK+ anaplastic large cell lymphoma cell lines; brentuximab synergizes and doxorubicin antagonizes.

Published in:

2018

By:

Hudson, Sandra;
Wang, Dongliang;
Middleton, Frank;
Nevaldine, Barbara H.;
Naous, Rana;
Hutchison, Robert E.

Publication type:

journal article

Connective Tissue Growth Factor and Insulin-Like Growth Factor 2 Show Upregulation in Early Growth Plate Radiorecovery Response following Irradiation.

Published in:

Cells Tissues Organs, 2007, v. 186, n. 3, p. 192, doi. 10.1159/000105673

By:

Yan Wang;
Mingliang Zhang;
Middleton, Frank A.;
Horton, Jason A.;
Pritchard, Meredith;
Spadaro, Joseph A.;
Farnum, Cornelia E.;
Damron, Timothy A.

Publication type:

Article

SHIP1 Deficiency in Inflammatory Bowel Disease Is Associated With Severe Crohn's Disease and Peripheral T Cell Reduction.

Published in:

Frontiers in Immunology, 2018, p. 1, doi. 10.3389/fimmu.2018.01100

By:

Fernandes, Sandra;
Srivastava, Neetu;
Sudan, Raki;
Middleton, Frank A.;
Shergill, Amandeep K.;
Ryan, James C.;
Kerr, William G.

Publication type:

Article

Systemic proteome phenotypes reveal defective metabolic flexibility in Mecp2 mutants.

Published in:

Human Molecular Genetics, 2024, v. 33, n. 1, p. 12, doi. 10.1093/hmg/ddad154

By:

Zlatic, Stephanie A;
Werner, Erica;
Surapaneni, Veda;
Lee, Chelsea E;
Gokhale, Avanti;
Singleton, Kaela;
Duong, Duc;
Crocker, Amanda;
Gentile, Karen;
Middleton, Frank;
Dalloul, Joseph Martin;
Liu, William Li-Yun;
Patgiri, Anupam;
Tarquinio, Daniel;
Carpenter, Randall;
Faundez, Victor

Publication type:

Article

Effect of lesion proximity on the regenerative response of long descending propriospinal neurons after spinal transection injury.

Published in:

2019

By:

Swieck, Kristen;
Conta-Steencken, Amanda;
Middleton, Frank A.;
Siebert, Justin R.;
Osterhout, Donna J.;
Stelzner, Dennis J.

Publication type:

journal article

Prevention of hepatocarcinogenesis and increased susceptibility to acetaminophen-induced liver failure in transaldolase-deficient mice by N-acetylcysteine.

Published in:

2009

By:

Hanczko, Robert;
Fernandez, David R.;
Doherty, Edward;
Yueming Qian;
Vas, Gyorgy;
Niland, Brian;
Telarico, Tiffany;
Garba, Adinoyi;
Banerjee, Sanjay;
Middleton, Frank A.;
Barrett, Donna;
Barcza, Maureen;
Banki, Katalin;
Landas, Steve K.;
Perl, Andras;
Qian, Yueming

Publication type:

journal article

Associations Between Neurodevelopmental Genes, Neuroanatomy, and Ultra High Risk Symptoms of Psychosis in 22q11.2 Deletion Syndrome.

Published in:

American Journal of Medical Genetics. Part B: Neuropsychiatric Genetics, 2017, v. 174, n. 3, p. 295, doi. 10.1002/ajmg.b.32515

By:

Thompson, Carlie A.;
Karelis, Jason;
Middleton, Frank A.;
Gentile, Karen;
Coman, Ioana L.;
Radoeva, Petya D.;
Mehta, Rashi;
Fremont, Wanda P.;
Antshel, Kevin M.;
Faraone, Stephen V.;
Kates, Wendy R.

Publication type:

Article

Characterizing runs of homozygosity and their impact on risk for psychosis in a population isolate.

Published in:

American Journal of Medical Genetics. Part B: Neuropsychiatric Genetics, 2014, v. 165B, n. 6, p. 521, doi. 10.1002/ajmg.b.32255

By:

Melhem, Nadine M.;
Lu, Cong;
Dresbold, Cara;
Middleton, Frank A.;
Klei, Lambertus;
Wood, Shawn;
Faraone, Stephen V.;
Vinogradov, Sophia;
Tiobech, Josepha;
Yano, Victor;
Roeder, Kathryn;
Byerley, William;
Myles‐Worsley, Marina;
Devlin, Bernie

Publication type:

Article

Deletion at the SLC1A1 Glutamate Transporter Gene Co-Segregates With Schizophrenia and Bipolar Schizoaffective Disorder in a 5-Generation Family.

Published in:

American Journal of Medical Genetics. Part B: Neuropsychiatric Genetics, 2013, v. 162B, n. 2, p. 87, doi. 10.1002/ajmg.b.32125

By:

Myles‐Worsley, Marina;
Tiobech, Josepha;
Browning, Sharon R.;
Korn, Jeremy;
Goodman, Sarah;
Gentile, Karen;
Melhem, Nadine;
Byerley, William;
Faraone, Stephen V.;
Middleton, Frank A.

Publication type:

Article

Genetic Overlap of Schizophrenia and Bipolar Disorder in a High-Density Linkage Survey in the Portuguese Island Population.

Published in:

American Journal of Medical Genetics. Part B: Neuropsychiatric Genetics, 2012, v. 159B, n. 4, p. 383, doi. 10.1002/ajmg.b.32041

By:

Fanous, Ayman H.;
Middleton, Frank A.;
Gentile, Karen;
Amdur, Richard L.;
Maher, Brion S.;
Zhongming Zhao;
Jingchun Sun;
Medeiros, Helena;
Carvalho, Celia;
Ferreira, Susana R.;
Macedo, Antonio;
Knowles, James A.;
Azevedo, Maria H.;
Pato, Michele T.;
Pato, Carlos N.

Publication type:

Article

Reduced Slc1a1 expression is associated with neuroinflammation and impaired sensorimotor gating and cognitive performance in mice: Implications for schizophrenia.

Published in:

PLoS ONE, 2017, v. 12, n. 9, p. 1, doi. 10.1371/journal.pone.0183854

By:

Afshari, Parisa;
Yao, Wei-Dong;
Middleton, Frank A.

Publication type:

Article

Analysis of SHIP1 expression and activity in Crohn’s disease patients.

Published in:

PLoS ONE, 2017, v. 12, n. 8, p. 1, doi. 10.1371/journal.pone.0182308

By:

Somasundaram, Rajesh;
Fernandes, Sandra;
Deuring, Jasper J.;
de Haar, Colin;
Kuipers, Ernst J.;
Vogelaar, Lauran;
Middleton, Frank A.;
van der Woude, C. Janneke;
Peppelenbosch, Maikel P.;
Kerr, William G.;
Fuhler, Gwenny M.

Publication type:

Article

Heterogeneity of p53 dependent genomic responses following ethanol exposure in a developmental mouse model of fetal alcohol spectrum disorder.

Published in:

PLoS ONE, 2017, v. 12, n. 7, p. 1, doi. 10.1371/journal.pone.0180873

By:

Camargo Moreno, Maria;
Mooney, Sandra M.;
Middleton, Frank A.

Publication type:

Article

Distinct Phenotypes of Inflammation Associated Macrophages and Microglia in the Prefrontal Cortex Schizophrenia Compared to Controls.

Published in:

Frontiers in Neuroscience, 2022, v. 16, p. 1, doi. 10.3389/fnins.2022.858989

By:

Yunting Zhu;
Webster, Maree J.;
Murphy, Caitlin E.;
Middleton, Frank A.;
Massa, Paul T.;
Chunyu Liu;
Dai, Rujia;
Weickert, Cyndi Shannon

Publication type:

Article

Genomic investigation of α-synuclein multiplication and parkinsonism.

Published in:

Annals of Neurology, 2008, v. 63, n. 6, p. 743, doi. 10.1002/ana.21380

By:

Ross, Owen A.;
Braithwaite, Adam T.;
Skipper, Lisa M.;
Kachergus, Jennifer;
Hulihan, Mary M.;
Middleton, Frank A.;
Nishioka, Kenya;
Fuchs, Julia;
Gasser, Thomas;
Maraganore, Demetrius M.;
Adler, Charles H.;
Larvor, Lydie;
Chartier-Harlin, Marie-Christine;
Nilsson, Christer;
Langston, J. William;
Gwinn, Katrina;
Hattori, Nobutaka;
Farrer, Matthew J.

Publication type:

Article

Altered Expression of 14-3-3 Genes in the Prefrontal Cortex of Subjects with Schizophrenia.

Published in:

Neuropsychopharmacology, 2005, v. 30, n. 5, p. 974, doi. 10.1038/sj.npp.1300674

By:

Middleton, Frank A.;
Peng, Lansha;
Lewis, David A.;
Levitt, Pat;
Mirnics, Karoly

Publication type:

Article

CELL DEATH TRANSCRIPTS OF THE TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY ARE INCREASED IN THE MIDBRAINS OF SCHIZOPHRENIA AND BIPOLAR DISORDER WITH HIGH INFLAMMATION AND ARE NEGATIVELY ASSOCIATED WITH DOPAMINE TRANSCRIPTS.

Published in:

International Journal of Neuropsychopharmacology, 2025, v. 28, p. i234, doi. 10.1093/ijnp/pyae059.411

By:

Mendez Victoriano, Gerardo;
Yunting Zhu;
Middleton, Frank;
Webster, Maree J.;
Weickert, Cynthia S.

Publication type:

Article

Saliva RNA Biomarkers of Gastrointestinal Dysfunction in Children With Autism and Neurodevelopmental Disorders: Potential Implications for Precision Medicine.

Published in:

Frontiers in Psychiatry, 2022, v. 13, p. 1, doi. 10.3389/fpsyt.2021.824933

By:

Beversdorf, David Q.;
Sohl, Kristin;
Levitskiy, David;
Tennant, Priscilla;
Goin-Kochel, Robin P.;
Shaffer, Rebecca C.;
Confair, Alexandra;
Middleton, Frank A.;
Hicks, Steven D.

Publication type:

Article

Association and linkage analyses of RGS4 polymorphisms in schizophrenia.

Published in:

Human Molecular Genetics, 2003, v. 12, n. 14, p. 1781, doi. 10.1093/hmg/ddg171

By:

Chowdari, Kodavali V.;
Mirnics, Karoly;
Semwal, Prachi;
Wood, Joel;
Lawrence, Elizabeth;
Bhatia, Triptish;
Deshpande, Smita N.;
Thelma, B.K.;
Ferrell, Robert E.;
Middleton, Frank A.;
Devlin, Bernie;
Levitt, Pat;
Lewis, David A.;
Nimgaonkar, Vishwajit L.

Publication type:

Article

Association and linkage analyses of RGS4 polymorphisms in schizophrenia.

Published in:

Human Molecular Genetics, 2002, v. 11, n. 12, p. 1373, doi. 10.1093/hmg/11.12.1373

By:

Chowdari, Kodavali V.;
Mirnics, Karoly;
Semwal, Prachi;
Wood, Joel;
Lawrence, Elizabeth;
Bhatia, Triptish;
Deshpande, Smita N.;
B.K., Thelma;
Ferrell, Robert E.;
Middleton, Frank A.;
Devlin, Bernie;
Levitt, Pat;
Lewis, David A.;
Nimgaonkar, Vishwajit L.

Publication type:

Article

Basal-ganglia ‘Projections’ to the Prefrontal Cortex of the Primate.

Published in:

Cerebral Cortex, 2002, v. 12, n. 9, p. 926, doi. 10.1093/cercor/12.9.926

By:

Middleton, Frank A.;
Strick, Peter L.

Publication type:

Article

Transforming growth factor β1 and ethanol affect transcription and translation of genes and proteins for cell adhesion molecules in B104 neuroblastoma cells.

Published in:

Journal of Neurochemistry, 2006, v. 97, n. 4, p. 1182, doi. 10.1111/j.1471-4159.2006.03858.x

By:

Miller, Michael W.;
Mooney, Sandra M.;
Middleton, Frank A.

Publication type:

Article

Briefly noted.

Published in:

1992

By:

Middleton, Frank

Publication type:

Book Review

Reviewer selection biases editorial decisions on manuscripts.

Published in:

Journal of Neurochemistry, 2018, v. 146, n. 1, p. 21, doi. 10.1111/jnc.14314

By:

Hausmann, Laura;
Schweitzer, Barbara;
Middleton, Frank A.;
Schulz, Jörg B.

Publication type:

Article

The de novo autism spectrum disorder RELN R2290C mutation reduces Reelin secretion and increases protein disulfide isomerase expression.

Published in:

Journal of Neurochemistry, 2017, v. 142, n. 1, p. 89, doi. 10.1111/jnc.14045

By:

Lammert, Dawn B.;
Middleton, Frank A.;
Pan, Jen;
Olson, Eric C.;
Howell, Brian W.

Publication type:

Article

Ethanol-induced methylation of cell cycle genes in neural stem cells.

Published in:

Journal of Neurochemistry, 2010, v. 114, n. 6, p. 1767, doi. 10.1111/j.1471-4159.2010.06886.x

By:

Hicks, Steven D.;
Middleton, Frank A.;
Miller, Michael W.

Publication type:

Article

High Sensitivity and Specificity of Dormitory-Level Wastewater Surveillance for COVID-19 during Fall Semester 2020 at Syracuse University, New York.

Published in:

International Journal of Environmental Research & Public Health, 2022, v. 19, n. 8, p. 4851, doi. 10.3390/ijerph19084851

By:

Godinez, Alex;
Hill, Dustin;
Dandaraw, Bryan;
Green, Hyatt;
Kilaru, Pruthvi;
Middleton, Frank;
Run, Sythong;
Kmush, Brittany L.;
Larsen, David A.

Publication type:

Article

Mitochondrial protein import clogging as a mechanism of disease.

Published in:

eLife, 2023, p. 1, doi. 10.7554/eLife.84330

By:

Coyne, Liam P.;
Xiaowen Wang;
Jiyao Song;
de Jong, Ebbing;
Schneider, Karin;
Massa, Paul T.;
Middleton, Frank A.;
Becker, Thomas;
Xin Jie Chen

Publication type:

Article

Infection with Borrelia burgdorferi Increases the Replication and Dissemination of Coinfecting Powassan Virus in Ixodes scapularis Ticks.

Published in:

Viruses (1999-4915), 2022, v. 14, n. 7, p. N.PAG, doi. 10.3390/v14071584

By:

Hart, Charles E.;
Middleton, Frank A.;
Thangamani, Saravanan

Publication type:

Article

Evidence‐based use of scalable biomarkers to increase diagnostic efficiency and decrease the lifetime costs of autism.

Published in:

Autism Research: Official Journal of the International Society for Autism Research, 2021, v. 14, n. 6, p. 1271, doi. 10.1002/aur.2498

By:

Frazier, Thomas W.;
Coury, Daniel L.;
Sohl, Kristin;
Wagner, Kayla E.;
Uhlig, Richard;
Hicks, Steven D.;
Middleton, Frank A.

Publication type:

Article

Oral microbiome activity in children with autism spectrum disorder.

Published in:

Autism Research: Official Journal of the International Society for Autism Research, 2018, v. 11, n. 9, p. 1286, doi. 10.1002/aur.1972

By:

Hicks, Steven D.;
Uhlig, Richard;
Afshari, Parisa;
Williams, Jeremy;
Chroneos, Maria;
Tierney‐Aves, Cheryl;
Wagner, Kayla;
Middleton, Frank A.

Publication type:

Article

Quantification and persistence of COVID‐19 virus in recently deceased individuals before and after embalming.

Published in:

Anatomical Sciences Education, 2023, v. 16, n. 5, p. 802, doi. 10.1002/ase.2300

By:

Gitto, Lorenzo;
Middleton, Frank A.;
Reynolds, Erin S.;
Thangamani, Saravanan;
Jaeger, Daniel A.;
Mihaila, Dana M.

Publication type:

Article

Trajectory of change in brain complement factors from neonatal to young adult humans.

Published in:

Journal of Neurochemistry, 2021, v. 157, n. 3, p. 479, doi. 10.1111/jnc.15241

By:

Sager, Rachel E. H.;
Walker, Adam K.;
Middleton, Frank;
Robinson, Kate;
Webster, Maree J.;
Weickert, Cynthia Shannon

Publication type:

Article

Salivary miRNA profiles identify children with autism spectrum disorder, correlate with adaptive behavior, and implicate ASD candidate genes involved in neurodevelopment.

Published in:

2016

By:

Hicks, Steven D.;
Ignacio, Cherry;
Gentile, Karen;
Middleton, Frank A.

Publication type:

journal article

A role for genes in the ‘caregiver stress process’?

Published in:

Translational Psychiatry, 2018, v. 8, n. 1, p. 1, doi. 10.1038/s41398-018-0275-7

By:

Wolf, Douglas A.;
Middleton, Frank A.

Publication type:

Article

An Adaptive Multivariate Two-Sample Test With Application to Microbiome Differential Abundance Analysis.

Published in:

Frontiers in Genetics, 2019, p. N.PAG, doi. 10.3389/fgene.2019.00350

By:

Banerjee, Kalins;
Zhao, Ni;
Srinivasan, Arun;
Xue, Lingzhou;
Hicks, Steven D.;
Middleton, Frank A.;
Wu, Rongling;
Zhan, Xiang

Publication type:

Article

Validation of a Salivary RNA Test for Childhood Autism Spectrum Disorder.

Published in:

Frontiers in Genetics, 2018, p. N.PAG, doi. 10.3389/fgene.2018.00534

By:

Hicks, Steven D.;
Rajan, Alexander T.;
Wagner, Kayla E.;
Barns, Sarah;
Carpenter, Randall L.;
Middleton, Frank A.

Publication type:

Article

Parent Perspectives Towards Genetic and Epigenetic Testing for Autism Spectrum Disorder.

Published in:

Journal of Autism & Developmental Disorders, 2020, v. 50, n. 9, p. 3114, doi. 10.1007/s10803-019-03990-6

By:

Wagner, Kayla E.;
McCormick, Jennifer B.;
Barns, Sarah;
Carney, Molly;
Middleton, Frank A.;
Hicks, Steven D.

Publication type:

Article

Differential Expression of SLC9A9 and Interacting Molecules in the Hippocampus of Rat Models for Attention Deficit/Hyperactivity Disorder.

Published in:

Developmental Neuroscience, 2012, v. 34, n. 2/3, p. 218, doi. 10.1159/000338813

By:

Zhang-James, Yanli;
Middleton, Frank A.;
Sagvolden, Terje;
Faraone, Stephen V.

Publication type:

Article

Molecular Substrates of Social Avoidance Seen following Prenatal Ethanol Exposure and Its Reversal by Social Enrichment.

Published in:

Developmental Neuroscience, 2012, v. 34, n. 2/3, p. 115, doi. 10.1159/000337858

By:

Middleton, Frank A.;
Varlinskaya, Elana I.;
Mooney, Sandra M.

Publication type:

Article

The oral microbiome of early stage Parkinson’s disease and its relationship with functional measures of motor and non-motor function.

Published in:

PLoS ONE, 2019, v. 14, n. 6, p. 1, doi. 10.1371/journal.pone.0218252

By:

Mihaila, Dragos;
Donegan, Jordan;
Barns, Sarah;
LaRocca, Daria;
Du, Qian;
Zheng, Danny;
Vidal, Michael;
Neville, Christopher;
Uhlig, Richard;
Middleton, Frank A.

Publication type:

Article