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Generalized Modules for Membrane Antigens (GMMA), an outer membrane vesicle‐based vaccine platform, for efficient viral antigen delivery.
- Published in:
- Journal of Extracellular Vesicles, 2022, v. 11, n. 11, p. 1, doi. 10.1002/jev2.12247
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- Publication type:
- Article
Rationalizing the design of a broad coverage Shigella vaccine based on evaluation of immunological cross-reactivity among S. flexneri serotypes.
- Published in:
- PLoS Neglected Tropical Diseases, 2021, v. 15, n. 10, p. 1, doi. 10.1371/journal.pntd.0009826
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- Publication type:
- Article
Sugar-Protein Connectivity Impacts on the Immunogenicity of Site-Selective Salmonella O-Antigen Glycoconjugate Vaccines.
- Published in:
- Angewandte Chemie International Edition, 2015, v. 54, n. 45, p. 13198, doi. 10.1002/anie.201506112
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- Publication type:
- Article
Frontispiece: Sugar-Protein Connectivity Impacts on the Immunogenicity of Site-Selective Salmonella O-Antigen Glycoconjugate Vaccines.
- Published in:
- 2015
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- Publication type:
- Other
Toward a Shigella Vaccine: Opportunities and Challenges to Fight an Antimicrobial-Resistant Pathogen.
- Published in:
- International Journal of Molecular Sciences, 2023, v. 24, n. 5, p. 4649, doi. 10.3390/ijms24054649
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- Publication type:
- Article
Exploring the Role of GMMA Components in the Immunogenicity of a 4-Valent Vaccine against Shigella.
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- International Journal of Molecular Sciences, 2023, v. 24, n. 3, p. 2742, doi. 10.3390/ijms24032742
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- Publication type:
- Article
Comparison and Optimization of Quantification Methods for Shigella flexneri Serotype 6 O-antigen Containing Galacturonic Acid and Methyl-Pentose.
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- International Journal of Molecular Sciences, 2021, v. 22, n. 22, p. 12160, doi. 10.3390/ijms222212160
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- Publication type:
- Article
Novel Simple Conjugation Chemistries for Decoration of GMMA with Heterologous Antigens.
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- International Journal of Molecular Sciences, 2021, v. 22, n. 19, p. 10180, doi. 10.3390/ijms221910180
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- Publication type:
- Article
Prophylaxis and Treatment against Klebsiella pneumoniae : Current Insights on This Emerging Anti-Microbial Resistant Global Threat.
- Published in:
- International Journal of Molecular Sciences, 2021, v. 22, n. 8, p. 4042, doi. 10.3390/ijms22084042
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- Publication type:
- Article
Myricetin as an Antivirulence Compound Interfering with a Morphological Transformation into Coccoid Forms and Potentiating Activity of Antibiotics against Helicobacter pylori.
- Published in:
- International Journal of Molecular Sciences, 2021, v. 22, n. 5, p. 2695, doi. 10.3390/ijms22052695
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- Publication type:
- Article
Molecular Insights into an Antibiotic Enhancer Action of New Morpholine-Containing 5-Arylideneimidazolones in the Fight against MDR Bacteria.
- Published in:
- International Journal of Molecular Sciences, 2021, v. 22, n. 4, p. 2062, doi. 10.3390/ijms22042062
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- Publication type:
- Article
Effect of O-Antigen Chain Length Regulation on the Immunogenicity of Shigella and Salmonella Generalized Modules for Membrane Antigens (GMMA).
- Published in:
- International Journal of Molecular Sciences, 2021, v. 22, n. 3, p. 1309, doi. 10.3390/ijms22031309
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- Publication type:
- Article
Rational Design of a Glycoconjugate Vaccine against Group A Streptococcus.
- Published in:
- International Journal of Molecular Sciences, 2020, v. 21, n. 22, p. 8558, doi. 10.3390/ijms21228558
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- Publication type:
- Article
OMV Vaccines and the Role of TLR Agonists in Immune Response.
- Published in:
- International Journal of Molecular Sciences, 2020, v. 21, n. 12, p. 4416, doi. 10.3390/ijms21124416
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- Publication type:
- Article
Modeling 1-Cyano-4-Dimethylaminopyridine Tetrafluoroborate (CDAP) Chemistry to Design Glycoconjugate Vaccines with Desired Structural and Immunological Characteristics.
- Published in:
- Vaccines, 2024, v. 12, n. 7, p. 707, doi. 10.3390/vaccines12070707
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- Publication type:
- Article
Testing a Recombinant Form of Tetanus Toxoid as a Carrier Protein for Glycoconjugate Vaccines.
- Published in:
- Vaccines, 2023, v. 11, n. 12, p. 1770, doi. 10.3390/vaccines11121770
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- Publication type:
- Article
Enhanced Systemic Humoral Immune Response Induced in Mice by Generalized Modules for Membrane Antigens (GMMA) Is Associated with Affinity Maturation and Isotype Switching.
- Published in:
- Vaccines, 2023, v. 11, n. 7, p. 1219, doi. 10.3390/vaccines11071219
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- Publication type:
- Article
Investigating the Role of Antigen Orientation on the Immune Response Elicited by Neisseria meningitidis Factor H Binding Protein on GMMA.
- Published in:
- Vaccines, 2022, v. 10, n. 8, p. 1182, doi. 10.3390/vaccines10081182
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- Publication type:
- Article
GMMA as an Alternative Carrier for a Glycoconjugate Vaccine against Group A Streptococcus.
- Published in:
- Vaccines, 2022, v. 10, n. 7, p. N.PAG, doi. 10.3390/vaccines10071034
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- Publication type:
- Article
Towards a Four-Component GMMA-Based Vaccine against Shigella.
- Published in:
- Vaccines, 2022, v. 10, n. 2, p. 328, doi. 10.3390/vaccines10020328
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- Publication type:
- Article
Conformational and Immunogenicity Studies of the Shigella flexneri Serogroup 6 O-Antigen: The Effect of O-Acetylation.
- Published in:
- Vaccines, 2021, v. 9, n. 5, p. 432, doi. 10.3390/vaccines9050432
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- Publication type:
- Article
Stability of Outer Membrane Vesicles-Based Vaccines, Identifying the Most Appropriate Methods to Detect Changes in Vaccine Potency.
- Published in:
- Vaccines, 2021, v. 9, n. 3, p. 229, doi. 10.3390/vaccines9030229
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- Publication type:
- Article
GMMA Is a Versatile Platform to Design Effective Multivalent Combination Vaccines.
- Published in:
- Vaccines, 2020, v. 8, n. 3, p. 540, doi. 10.3390/vaccines8030540
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- Publication type:
- Article
GMMA and Glycoconjugate Approaches Compared in Mice for the Development of a Vaccine against Shigella flexneri Serotype 6.
- Published in:
- Vaccines, 2020, v. 8, n. 2, p. 160, doi. 10.3390/vaccines8020160
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- Publication type:
- Article
Complement-mediated serum bactericidal activity of antibodies elicited by the Shigella sonnei GMMA vaccine in adults from a shigellosisendemic country: Exploratory analysis of a Phase 2a randomized study.
- Published in:
- Frontiers in Immunology, 2022, v. 13, p. 1, doi. 10.3389/fimmu.2022.971866
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- Publication type:
- Article
Dissecting in Vitro the Activation of Human Immune Response Induced by Shigella sonnei GMMA.
- Published in:
- Frontiers in Cellular & Infection Microbiology, 2022, v. 12, p. 1, doi. 10.3389/fcimb.2022.767153
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- Publication type:
- Article
Bactericidal Immunity to Salmonella in Africans and Mechanisms Causing Its Failure in HIV Infection.
- Published in:
- PLoS Neglected Tropical Diseases, 2016, v. 10, n. 4, p. 1, doi. 10.1371/journal.pntd.0004604
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- Publication type:
- Article
Relationship between Antibody Susceptibility and Lipopolysaccharide O-Antigen Characteristics of Invasive and Gastrointestinal Nontyphoidal Salmonellae Isolates from Kenya.
- Published in:
- PLoS Neglected Tropical Diseases, 2015, v. 9, n. 3, p. 1, doi. 10.1371/journal.pntd.0003573
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- Publication type:
- Article
Relationship between Antibody Susceptibility and Lipopolysaccharide O-Antigen Characteristics of Invasive and Gastrointestinal Nontyphoidal Salmonellae Isolates from Kenya.
- Published in:
- PLoS Neglected Tropical Diseases, 2015, v. 9, n. 3, p. 1, doi. 10.1371/journal.pntd.0003573
- By:
- Publication type:
- Article
Frontispiz: Sugar-Protein Connectivity Impacts on the Immunogenicity of Site-Selective Salmonella O-Antigen Glycoconjugate Vaccines.
- Published in:
- 2015
- By:
- Publication type:
- Other
Sugar-Protein Connectivity Impacts on the Immunogenicity of Site-Selective Salmonella O-Antigen Glycoconjugate Vaccines.
- Published in:
- Angewandte Chemie, 2015, v. 127, n. 45, p. 13396, doi. 10.1002/ange.201506112
- By:
- Publication type:
- Article
Quality by Design Framework Applied to GMMA Purification.
- Published in:
- AAPS Journal, 2024, v. 26, n. 2, p. 1, doi. 10.1208/s12248-024-00902-0
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- Publication type:
- Article
Strain Selection for Generation of O-Antigen-Based Glycoconjugate Vaccines against Invasive Nontyphoidal Salmonella Disease.
- Published in:
- PLoS ONE, 2015, v. 10, n. 10, p. 1, doi. 10.1371/journal.pone.0139847
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- Publication type:
- Article
O:2-CRM<sub>197</sub> Conjugates against Salmonella Paratyphi A.
- Published in:
- PLoS ONE, 2012, v. 7, n. 11, p. 1, doi. 10.1371/journal.pone.0047039
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- Publication type:
- Article
Safety, Immunogenicity and Dose Ranging of a New Vi-CRM<sub>197</sub> Conjugate Vaccine against Typhoid Fever: Randomized Clinical Testing in Healthy Adults.
- Published in:
- PLoS ONE, 2011, v. 6, n. 9, p. 1, doi. 10.1371/journal.pone.0025398
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- Publication type:
- Article
Characterization of Citrobacter sp. line 328 as source of Vi for Vi-CRM<sub>197</sub> glycoconjugate vaccine against Salmonella Typhi.
- Published in:
- Journal of Infection in Developing Countries, 2012, v. 6, n. 11, p. 763, doi. 10.3855/jidc.2495
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- Publication type:
- Article
Impact and Control of Sugar Size in Glycoconjugate Vaccines.
- Published in:
- Molecules, 2022, v. 27, n. 19, p. 6432, doi. 10.3390/molecules27196432
- By:
- Publication type:
- Article
Putative correlates of protection against shigellosis assessing immunomarkers across responses to S. sonnei investigational vaccine.
- Published in:
- NPJ Vaccines, 2024, v. 9, n. 1, p. 1, doi. 10.1038/s41541-024-00822-2
- By:
- Publication type:
- Article
A next-generation GMMA-based vaccine candidate to fight shigellosis.
- Published in:
- NPJ Vaccines, 2023, v. 8, n. 1, p. 1, doi. 10.1038/s41541-023-00725-8
- By:
- Publication type:
- Article
A next-generation GMMA-based vaccine candidate to fight shigellosis.
- Published in:
- NPJ Vaccines, 2023, v. 8, n. 1, p. 1, doi. 10.1038/s41541-023-00725-8
- By:
- Publication type:
- Article
Impact of O-Acetylation on S. flexneri 1b and 2a O-Antigen Immunogenicity in Mice.
- Published in:
- Microorganisms, 2021, v. 9, n. 11, p. 2360, doi. 10.3390/microorganisms9112360
- By:
- Publication type:
- Article
Development of a Monocyte Activation Test as an Alternative to the Rabbit Pyrogen Test for Mono- and Multi-Component Shigella GMMA-Based Vaccines.
- Published in:
- Microorganisms, 2021, v. 9, n. 7, p. 1375, doi. 10.3390/microorganisms9071375
- By:
- Publication type:
- Article
Neisseria meningitidis Factor H Binding Protein Surface Exposure on Salmonella Typhimurium GMMA Is Critical to Induce an Effective Immune Response against Both Diseases.
- Published in:
- Pathogens, 2021, v. 10, n. 6, p. 726, doi. 10.3390/pathogens10060726
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- Publication type:
- Article
Generalized Modules for Membrane Antigens as Carrier for Polysaccharides: Impact of Sugar Length, Density, and Attachment Site on the Immune Response Elicited in Animal Models.
- Published in:
- Frontiers in Immunology, 2021, v. 12, p. 1, doi. 10.3389/fimmu.2021.719315
- By:
- Publication type:
- Article
GMMA-Based Vaccines: The Known and The Unknown.
- Published in:
- Frontiers in Immunology, 2021, v. 12, p. 1, doi. 10.3389/fimmu.2021.715393
- By:
- Publication type:
- Article
Antibodies Elicited by the Shigella sonnei GMMA Vaccine in Adults Trigger Complement-Mediated Serum Bactericidal Activity: Results From a Phase 1 Dose Escalation Trial Followed by a Booster Extension.
- Published in:
- Frontiers in Immunology, 2021, v. 12, p. N.PAG, doi. 10.3389/fimmu.2021.671325
- By:
- Publication type:
- Article
O-Antigen decorations in Salmonella enterica play a key role in eliciting functional immune responses against heterologous serovars in animal models.
- Published in:
- Frontiers in Cellular & Infection Microbiology, 2024, p. 1, doi. 10.3389/fcimb.2024.1347813
- By:
- Publication type:
- Article
Functional assays to evaluate antibody-mediated responses against Shigella: a review.
- Published in:
- Frontiers in Cellular & Infection Microbiology, 2023, p. 1, doi. 10.3389/fcimb.2023.1171213
- By:
- Publication type:
- Article
Dissecting the contribution of O-Antigen and proteins to the immunogenicity of Shigella sonnei generalized modules for membrane antigens (GMMA).
- Published in:
- Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-020-80421-y
- By:
- Publication type:
- Article
Development and Application of a High-Throughput Method for the Purification and Analysis of Surface Carbohydrates from Klebsiella pneumoniae.
- Published in:
- Biology (2079-7737), 2024, v. 13, n. 4, p. 256, doi. 10.3390/biology13040256
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- Publication type:
- Article