Works matching AU Michelet, Robin

Results: 49

Nonlinear Mixed‐Effects Model of Z‐Endoxifen Concentrations in Tamoxifen‐Treated Patients from the CEPAM Cohort.

Published in:

Clinical Pharmacology & Therapeutics, 2024, v. 116, n. 3, p. 690, doi. 10.1002/cpt.3238

By:

Mc Laughlin, Anna M.;
Helland, Thomas;
Klima, Fenja;
Koolen, Stijn L.W.;
van Schaik, Ron H.N.;
Mathijssen, Ron H.J.;
Neven, Patrick;
Swen, Jesse J.;
Guchelaar, Henk‐Jan;
Dalenc, Florence;
White‐Koning, Melanie;
Michelet, Robin;
Mikus, Gerd;
Schroth, Werner;
Mürdter, Thomas;
Brauch, Hiltrud;
Schwab, Matthias;
Søiland, Håvard;
Mellgren, Gunnar;
Thomas, Fabienne

Publication type:

Article

Perspectives on Model‐Informed Precision Dosing in the Digital Health Era: Challenges, Opportunities, and Recommendations.

Published in:

Clinical Pharmacology & Therapeutics, 2021, v. 109, n. 1, p. 29, doi. 10.1002/cpt.2049

By:

Kluwe, Franziska;
Michelet, Robin;
Mueller‐Schoell, Anna;
Maier, Corinna;
Klopp‐Schulze, Lena;
Dyk, Madelé;
Mikus, Gerd;
Huisinga, Wilhelm;
Kloft, Charlotte

Publication type:

Article

Obesity Alters Endoxifen Plasma Levels in Young Breast Cancer Patients: A Pharmacometric Simulation Approach.

Published in:

Clinical Pharmacology & Therapeutics, 2020, v. 108, n. 3, p. 661, doi. 10.1002/cpt.1960

By:

Mueller‐Schoell, Anna;
Klopp‐Schulze, Lena;
Schroth, Werner;
Mürdter, Thomas;
Michelet, Robin;
Brauch, Hiltrud;
Huisinga, Wilhelm;
Joerger, Markus;
Neven, Patrick;
Koolen, Stijn L.W.;
Mathijssen, Ron H.J.;
Copson, Ellen;
Eccles, Diana;
Chen, Sylvia;
Chowbay, Balram;
Tfayli, Arafat;
Zgheib, Nathalie K.;
Schwab, Matthias;
Kloft, Charlotte

Publication type:

Article

Population pharmacokinetics of TLD-1, a novel liposomal doxorubicin, in a phase I trial.

Published in:

Cancer Chemotherapy & Pharmacology, 2024, v. 94, n. 3, p. 349, doi. 10.1007/s00280-024-04679-z

By:

Mc Laughlin, Anna M.;
Hess, Dagmar;
Michelet, Robin;
Colombo, Ilaria;
Haefliger, Simon;
Bastian, Sara;
Rabaglio, Manuela;
Schwitter, Michael;
Fischer, Stefanie;
Eckhardt, Katrin;
Hayoz, Stefanie;
Kopp, Christoph;
Klose, Marian;
Sessa, Cristiana;
Stathis, Anastasios;
Halbherr, Stefan;
Huisinga, Wilhelm;
Joerger, Markus;
Kloft, Charlotte

Publication type:

Article

CYP2D6 phenotype explains reported yohimbine concentrations in four severe acute intoxications.

Published in:

Archives of Toxicology, 2021, v. 95, n. 8, p. 2867, doi. 10.1007/s00204-021-03082-4

By:

Mueller-Schoell, Anna;
Michelet, Robin;
Weinelt, Ferdinand;
Kloft, Charlotte;
Mikus, Gerd

Publication type:

Article

Constitutive Cell Proliferation Regulating Inhibitor of Protein Phosphatase 2A (CIP2A) Mediates Drug Resistance to Erlotinib in an EGFR Activating Mutated NSCLC Cell Line.

Published in:

Cells (2073-4409), 2021, v. 10, n. 4, p. 716, doi. 10.3390/cells10040716

By:

Saafan, Hisham;
Alahdab, Ahmad;
Michelet, Robin;
Gohlke, Linus;
Ziemann, Janine;
Holdenrieder, Stefan;
McLaughlin, Katie-May;
Wass, Mark N.;
Cinatl Jr., Jindrich;
Michaelis, Martin;
Kloft, Charlotte;
Ritter, Christoph A;
Gray, Steven G.

Publication type:

Article

Ulcerative Colitis and Acute Severe Ulcerative Colitis Patients Are Overlooked in Infliximab Population Pharmacokinetic Models: Results from a Comprehensive Review.

Published in:

Pharmaceutics, 2022, v. 14, n. 10, p. N.PAG, doi. 10.3390/pharmaceutics14102095

By:

Démaris, Alix;
Widigson, Ella S. K.;
Ilvemark, Johan F. K. F.;
Steenholdt, Casper;
Seidelin, Jakob B.;
Huisinga, Wilhelm;
Michelet, Robin;
Aulin, Linda B. S.;
Kloft, Charlotte

Publication type:

Article

The Impact of Low Cardiac Output on Propofol Pharmacokinetics across Age Groups—An Investigation Using Physiologically Based Pharmacokinetic Modelling.

Published in:

Pharmaceutics, 2022, v. 14, n. 9, p. N.PAG, doi. 10.3390/pharmaceutics14091957

By:

Allegaert, Karel;
Abbasi, Mohammad Yaseen;
Michelet, Robin;
Olafuyi, Olusola

Publication type:

Article

Towards the Elucidation of the Pharmacokinetics of Voriconazole: A Quantitative Characterization of Its Metabolism.

Published in:

Pharmaceutics, 2022, v. 14, n. 3, p. 477, doi. 10.3390/pharmaceutics14030477

By:

Schulz, Josefine;
Thomas, Antonia;
Saleh, Ayatallah;
Mikus, Gerd;
Kloft, Charlotte;
Michelet, Robin

Publication type:

Article

Development of a Model-Informed Dosing Tool to Optimise Initial Antibiotic Dosing—A Translational Example for Intensive Care Units.

Published in:

Pharmaceutics, 2021, v. 13, n. 12, p. 2128, doi. 10.3390/pharmaceutics13122128

By:

Weinelt, Ferdinand Anton;
Stegemann, Miriam Songa;
Theloe, Anja;
Pfäfflin, Frieder;
Achterberg, Stephan;
Schmitt, Lisa;
Huisinga, Wilhelm;
Michelet, Robin;
Hennig, Stefanie;
Kloft, Charlotte

Publication type:

Article

Similar Piperacillin/Tazobactam Target Attainment in Obese versus Nonobese Patients despite Differences in Interstitial Tissue Fluid Pharmacokinetics.

Published in:

Pharmaceutics, 2021, v. 13, n. 9, p. 1380, doi. 10.3390/pharmaceutics13091380

By:

Busse, David;
Simon, Philipp;
Petroff, David;
Dorn, Christoph;
Schmitt, Lisa;
Bindellini, Davide;
Kratzer, Alexander;
Dietrich, Arne;
Zeitlinger, Markus;
Huisinga, Wilhelm;
Michelet, Robin;
Wrigge, Hermann;
Kloft, Charlotte

Publication type:

Article

The Use of Translational Modelling and Simulation to Develop Immunomodulatory Therapy as an Adjunct to Antibiotic Treatment in the Context of Pneumonia.

Published in:

Pharmaceutics, 2021, v. 13, n. 5, p. 601, doi. 10.3390/pharmaceutics13050601

By:

Michelet, Robin;
Ursino, Moreno;
Boulet, Sandrine;
Franck, Sebastian;
Casilag, Fiordiligie;
Baldry, Mara;
Rolff, Jens;
van Dyk, Madelé;
Wicha, Sebastian G.;
Sirard, Jean-Claude;
Comets, Emmanuelle;
Zohar, Sarah;
Kloft, Charlotte;
Sanjuán, Victor Mangas

Publication type:

Article

A Model-Based Pharmacokinetic/Pharmacodynamic Analysis of the Combination of Amoxicillin and Monophosphoryl Lipid A Against S. pneumoniae in Mice.

Published in:

Pharmaceutics, 2021, v. 13, n. 4, p. 469, doi. 10.3390/pharmaceutics13040469

By:

Franck, Sebastian;
Michelet, Robin;
Casilag, Fiordiligie;
Sirard, Jean-Claude;
Wicha, Sebastian G.;
Kloft, Charlotte;
Mangas Sanjuán, Victor;
Troconiz, Inaki F.

Publication type:

Article

Model-Informed Target Morning 17α-Hydroxyprogesterone Concentrations in Dried Blood Spots for Pediatric Congenital Adrenal Hyperplasia Patients.

Published in:

Pharmaceuticals (14248247), 2023, v. 16, n. 3, p. 464, doi. 10.3390/ph16030464

By:

Stachanow, Viktoria;
Neumann, Uta;
Blankenstein, Oliver;
Alder-Baerens, Nele;
Bindellini, Davide;
Hindmarsh, Peter;
Ross, Richard J.;
Whitaker, Martin J.;
Melin, Johanna;
Huisinga, Wilhelm;
Michelet, Robin;
Kloft, Charlotte

Publication type:

Article

Simulation-Based Assessment of the Impact of Non-Adherence on Endoxifen Target Attainment in Different Tamoxifen Dosing Strategies.

Published in:

Pharmaceuticals (14248247), 2021, v. 14, n. 2, p. 115, doi. 10.3390/ph14020115

By:

Mueller-Schoell, Anna;
Klopp-Schulze, Lena;
Michelet, Robin;
van Dyk, Madelé;
Mürdter, Thomas E.;
Schwab, Matthias;
Joerger, Markus;
Huisinga, Wilhelm;
Mikus, Gerd;
Kloft, Charlotte;
Ciccolini, Joseph

Publication type:

Article

Microdialysis of Voriconazole and its N-Oxide Metabolite: Amalgamating Knowledge of Distribution and Metabolism Processes in Humans.

Published in:

Pharmaceutical Research, 2022, v. 39, n. 12, p. 3279, doi. 10.1007/s11095-022-03407-7

By:

Schulz, Josefine;
Michelet, Robin;
Zeitlinger, Markus;
Mikus, Gerd;
Kloft, Charlotte

Publication type:

Article

Microdialysis of Drug and Drug Metabolite: a Comprehensive In Vitro Analysis for Voriconazole and Voriconazole N-oxide.

Published in:

Pharmaceutical Research, 2022, v. 39, n. 11, p. 2991, doi. 10.1007/s11095-022-03292-0

By:

Schulz, Josefine;
Michelet, Robin;
Zeitlinger, Markus;
Mikus, Gerd;
Kloft, Charlotte

Publication type:

Article

Evaluation of a Meropenem and Piperacillin Monitoring Program in Intensive Care Unit Patients Calls for the Regular Assessment of Empirical Targets and Easy-to-Use Dosing Decision Tools.

Published in:

Antibiotics (2079-6382), 2022, v. 11, n. 6, p. 758, doi. 10.3390/antibiotics11060758

By:

Weinelt, Ferdinand Anton;
Stegemann, Miriam Songa;
Theloe, Anja;
Pfäfflin, Frieder;
Achterberg, Stephan;
Weber, Franz;
Dübel, Lucas;
Mikolajewska, Agata;
Uhrig, Alexander;
Kiessling, Peggy;
Huisinga, Wilhelm;
Michelet, Robin;
Hennig, Stefanie;
Kloft, Charlotte

Publication type:

Article

Novel Pharmacokinetic/Pharmacodynamic Parameters Quantify the Exposure–Effect Relationship of Levofloxacin against Fluoroquinolone-Resistant Escherichia coli.

Published in:

Antibiotics (2079-6382), 2021, v. 10, n. 6, p. 615, doi. 10.3390/antibiotics10060615

By:

Seeger, Johanna;
Guenther, Sebastian;
Schaufler, Katharina;
Heiden, Stefan E.;
Michelet, Robin;
Kloft, Charlotte

Publication type:

Article

Evaluation of the MeroRisk Calculator, A User-Friendly Tool to Predict the Risk of Meropenem Target Non-Attainment in Critically Ill Patients.

Published in:

Antibiotics (2079-6382), 2021, v. 10, n. 4, p. 468, doi. 10.3390/antibiotics10040468

By:

Liebchen, Uwe;
Klose, Marian;
Paal, Michael;
Vogeser, Michael;
Zoller, Michael;
Schroeder, Ines;
Schmitt, Lisa;
Huisinga, Wilhelm;
Michelet, Robin;
Zander, Johannes;
Scharf, Christina;
Weinelt, Ferdinand A.;
Kloft, Charlotte

Publication type:

Article

A quantitative modeling framework to understand the physiology of the hypothalamic-pituitary-adrenal axis and interaction with cortisol replacement therapy.

Published in:

Journal of Pharmacokinetics & Pharmacodynamics, 2024, v. 51, n. 6, p. 809, doi. 10.1007/s10928-024-09934-7

By:

Bindellini, Davide;
Michelet, Robin;
Aulin, Linda B. S.;
Melin, Johanna;
Neumann, Uta;
Blankenstein, Oliver;
Huisinga, Wilhelm;
Whitaker, Martin J.;
Ross, Richard;
Kloft, Charlotte

Publication type:

Article

The use of PBPK modeling across the pediatric age range using propofol as a case.

Published in:

Journal of Pharmacokinetics & Pharmacodynamics, 2018, v. 45, n. 6, p. 765, doi. 10.1007/s10928-018-9607-8

By:

Michelet, Robin;
Van Bocxlaer, Jan;
Allegaert, Karel;
Vermeulen, An

Publication type:

Article

Physiologically Based Pharmacokinetic Predictions of Tramadol Exposure Throughout Pediatric Life: an Analysis of the Different Clearance Contributors with Emphasis on CYP2D6 Maturation.

Published in:

AAPS Journal, 2015, v. 17, n. 6, p. 1376, doi. 10.1208/s12248-015-9803-z

By:

T'jollyn, Huybrecht;
Snoeys, Jan;
Vermeulen, An;
Michelet, Robin;
Cuyckens, Filip;
Mannens, Geert;
Peer, Achiel;
Annaert, Pieter;
Allegaert, Karel;
Bocxlaer, Jan;
Boussery, Koen

Publication type:

Article

Which Analysis Approach Is Adequate to Leverage Clinical Microdialysis Data? A Quantitative Comparison to Investigate Exposure and Reponse Exemplified by Levofloxacin.

Published in:

Pharmaceutical Research, 2021, v. 38, n. 3, p. 381, doi. 10.1007/s11095-021-02994-1

By:

Busse, David;
Schaeftlein, André;
Solms, Alexander;
Ilia, Luis;
Michelet, Robin;
Zeitlinger, Markus;
Huisinga, Wilhelm;
Kloft, Charlotte

Publication type:

Article

Correction to: Therapeutic drug monitoring of oral targeted antineoplastic drugs.

Published in:

2021

By:

Mueller-Schoell, Anna;
Groenland, Stefanie L.;
Scherf-Clavel, Oliver;
van Dyk, Madelé;
Huisinga, Wilhelm;
Michelet, Robin;
Jaehde, Ulrich;
Steeghs, Neeltje;
Huitema, Alwin D. R.;
Kloft, Charlotte

Publication type:

Correction Notice

Therapeutic drug monitoring of oral targeted antineoplastic drugs.

Published in:

European Journal of Clinical Pharmacology, 2021, v. 77, n. 4, p. 441, doi. 10.1007/s00228-020-03014-8

By:

Mueller-Schoell, Anna;
Groenland, Stefanie L.;
Scherf-Clavel, Oliver;
van Dyk, Madelé;
Huisinga, Wilhelm;
Michelet, Robin;
Jaehde, Ulrich;
Steeghs, Neeltje;
Huitema, Alwin D.R.;
Kloft, Charlotte

Publication type:

Article

Claiming desmopressin therapeutic equivalence in children requires pediatric data: a population PKPD analysis.

Published in:

European Journal of Clinical Pharmacology, 2018, v. 74, n. 3, p. 297, doi. 10.1007/s00228-017-2386-0

By:

Michelet, Robin;
Dossche, Lien;
Van Herzeele, Charlotte;
Van Bocxlaer, Jan;
Vermeulen, An;
Vande Walle, Johan;
On behalf of the SAFE-PEDRUG consortium

Publication type:

Article

Exploring Dried Blood Spot Cortisol Concentrations as an Alternative for Monitoring Pediatric Adrenal Insufficiency Patients: A Model-Based Analysis.

Published in:

Frontiers in Pharmacology, 2022, v. 13, p. 1, doi. 10.3389/fphar.2022.819590

By:

Stachanow, Viktoria;
Neumann, Uta;
Blankenstein, Oliver;
Bindellini, Davide;
Melin, Johanna;
Ross, Richard;
Whitaker, Martin J.;
Huisinga, Wilhelm;
Michelet, Robin;
Kloft, Charlotte

Publication type:

Article

A Pooled Pharmacokinetic Analysis for Piperacillin/Tazobactam Across Different Patient Populations: From Premature Infants to the Elderly: A Pooled PK Analysis for Piperacillin/Tazobactam Across Different Patient Populations: D. Kong et al.

Published in:

Clinical Pharmacokinetics, 2025, v. 64, n. 1, p. 107, doi. 10.1007/s40262-024-01460-6

By:

Kong, Daming;
Roberts, Jason A.;
Lipman, Jeffrey;
Taccone, Fabio Silvio;
Cohen-Wolkowiez, Michael;
Sime, Fekade B.;
Tsai, Danny;
De Cock, Pieter A. J. G.;
Jaruratanasirikul, Sutep;
Dhaese, Sofie A. M.;
Udy, Andrew A.;
Felton, Timothy W.;
Michelet, Robin;
Thibault, Céline;
Koomen, Jeroen V.;
Eleveld, Douglas J.;
Struys, Michel M. R. F.;
De Waele, Jan J.;
Colin, Pieter J.;
Damen, Caroline

Publication type:

Article

Understanding Voriconazole Metabolism: A Middle-Out Physiologically-Based Pharmacokinetic Modelling Framework Integrating In Vitro and Clinical Insights.

Published in:

Clinical Pharmacokinetics, 2024, v. 63, n. 11, p. 1609, doi. 10.1007/s40262-024-01434-8

By:

Saleh, Ayatallah;
Schulz, Josefine;
Schlender, Jan-Frederik;
Aulin, Linda B. S.;
Konrad, Amrei-Pauline;
Kluwe, Franziska;
Mikus, Gerd;
Huisinga, Wilhelm;
Kloft, Charlotte;
Michelet, Robin

Publication type:

Article

Towards Model-Informed Precision Dosing of Voriconazole: Challenging Published Voriconazole Nonlinear Mixed-Effects Models with Real-World Clinical Data.

Published in:

Clinical Pharmacokinetics, 2023, v. 62, n. 10, p. 1461, doi. 10.1007/s40262-023-01274-y

By:

Kluwe, Franziska;
Michelet, Robin;
Huisinga, Wilhelm;
Zeitlinger, Markus;
Mikus, Gerd;
Kloft, Charlotte

Publication type:

Article

Quantification of the Time Course of CYP3A Inhibition, Activation, and Induction Using a Population Pharmacokinetic Model of Microdosed Midazolam Continuous Infusion.

Published in:

Clinical Pharmacokinetics, 2022, v. 61, n. 11, p. 1595, doi. 10.1007/s40262-022-01175-6

By:

Nassar, Yomna M.;
Hohmann, Nicolas;
Michelet, Robin;
Gottwalt, Katharina;
Meid, Andreas D.;
Burhenne, Jürgen;
Huisinga, Wilhelm;
Haefeli, Walter E.;
Mikus, Gerd;
Kloft, Charlotte

Publication type:

Article

Comparative Plasma and Interstitial Tissue Fluid Pharmacokinetics of Meropenem Demonstrate the Need for Increasing Dose and Infusion Duration in Obese and Non-obese Patients.

Published in:

Clinical Pharmacokinetics, 2022, v. 61, n. 5, p. 655, doi. 10.1007/s40262-021-01070-6

By:

Busse, David;
Simon, Philipp;
Schmitt, Lisa;
Petroff, David;
Dorn, Christoph;
Dietrich, Arne;
Zeitlinger, Markus;
Huisinga, Wilhelm;
Michelet, Robin;
Wrigge, Hermann;
Kloft, Charlotte

Publication type:

Article

An Integrated Paediatric Population PK/PD Analysis of dDAVP: How do PK Differences Translate to Clinical Outcomes?

Published in:

2020

By:

Michelet, Robin;
Dossche, Lien;
Van Herzeele, Charlotte;
De Bruyne, Pauline;
Gasthuys, Elke;
Van Bocxlaer, Jan;
Vande Walle, Johan;
Vermeulen, An

Publication type:

journal article

Effects of Food and Pharmaceutical Formulation on Desmopressin Pharmacokinetics in Children.

Published in:

2016

By:

Michelet, Robin;
Dossche, Lien;
Bruyne, Pauline;
Colin, Pieter;
Boussery, Koen;
Vande Walle, Johan;
Bocxlaer, Jan;
Vermeulen, An;
De Bruyne, Pauline;
Van Bocxlaer, Jan

Publication type:

journal article

No clinically relevant removal of meropenem by cytokine adsorber CytoSorb<sup>®</sup> in critically ill patients with sepsis or septic shock.

Published in:

2021

By:

Liebchen, Uwe;
Scharf, Christina;
Zoller, Michael;
Weinelt, Ferdinand;
Kloft, Charlotte;
the CytoMero collaboration team;
Michelet, Robin;
Schroeder, Ines;
Paal, Michael;
Vogeser, Michael;
Irlbeck, Michael;
Briegel, Josef;
Zander, Johannes;
Huisinga, Wilhelm;
CytoMero collaboration team

Publication type:

Letter

Bayesian framework for multi-source data integration-Application to human extrapolation from preclinical studies.

Published in:

Statistical Methods in Medical Research, 2024, v. 33, n. 4, p. 574, doi. 10.1177/09622802241231493

By:

Boulet, Sandrine;
Ursino, Moreno;
Michelet, Robin;
Aulin, Linda BS;
Kloft, Charlotte;
Comets, Emmanuelle;
Zohar, Sarah

Publication type:

Article

Rationale of a lower dexamethasone dose in prenatal congenital adrenal hyperplasia therapy based on pharmacokinetic modelling.

Published in:

European Journal of Endocrinology, 2021, v. 185, n. 3, p. 365, doi. 10.1530/EJE-21-0395

By:

Stachanow, Viktoria;
Neumann, Uta;
Blankenstein, Oliver;
Fuhr, Uwe;
Huisinga, Wilhelm;
Michelet, Robin;
Reisch, Nicole;
Kloft, Charlotte

Publication type:

Article

Personalized Dosing of Medicines for Children: A Primer on Pediatric Pharmacometrics for Clinicians.

Published in:

Pediatric Drugs, 2024, v. 26, n. 4, p. 365, doi. 10.1007/s40272-024-00633-x

By:

Meesters, Kevin;
Balbas-Martinez, Violeta;
Allegaert, Karel;
Downes, Kevin J.;
Michelet, Robin

Publication type:

Article

Pediatric Pharmacology of Desmopressin in Children with Enuresis: A Comprehensive Review.

Published in:

Pediatric Drugs, 2020, v. 22, n. 4, p. 369, doi. 10.1007/s40272-020-00401-7

By:

Gasthuys, Elke;
Dossche, Lien;
Michelet, Robin;
Nørgaard, Jens Peter;
Devreese, Mathias;
Croubels, Siska;
Vermeulen, An;
Van Bocxlaer, Jan;
Walle, Johan Vande

Publication type:

Article

C-Reactive Protein as an Early Predictor of Efficacy in Advanced Non-Small-Cell Lung Cancer Patients: A Tumor Dynamics-Biomarker Modeling Framework.

Published in:

Cancers, 2023, v. 15, n. 22, p. 5429, doi. 10.3390/cancers15225429

By:

Nassar, Yomna M.;
Ojara, Francis Williams;
Pérez-Pitarch, Alejandro;
Geiger, Kimberly;
Huisinga, Wilhelm;
Hartung, Niklas;
Michelet, Robin;
Holdenrieder, Stefan;
Joerger, Markus;
Kloft, Charlotte

Publication type:

Article

Early Survival Prediction Framework in CD19-Specific CAR-T Cell Immunotherapy Using a Quantitative Systems Pharmacology Model.

Published in:

Cancers, 2021, v. 13, n. 11, p. 2782, doi. 10.3390/cancers13112782

By:

Mueller-Schoell, Anna;
Puebla-Osorio, Nahum;
Michelet, Robin;
Green, Michael R.;
Künkele, Annette;
Huisinga, Wilhelm;
Strati, Paolo;
Chasen, Beth;
Neelapu, Sattva S.;
Yee, Cassian;
Kloft, Charlotte

Publication type:

Article

Computational Treatment Simulations to Assess the Need for Personalized Tamoxifen Dosing in Breast Cancer Patients of Different Biogeographical Groups.

Published in:

Cancers, 2021, v. 13, n. 10, p. 2432, doi. 10.3390/cancers13102432

By:

Mueller-Schoell, Anna;
Michelet, Robin;
Klopp-Schulze, Lena;
van Dyk, Madelé;
Mürdter, Thomas E.;
Schwab, Matthias;
Joerger, Markus;
Huisinga, Wilhelm;
Mikus, Gerd;
Kloft, Charlotte;
Jono, Hirofumi

Publication type:

Article

Novel insights into the complex pharmacokinetics of voriconazole: a review of its metabolism.

Published in:

Drug Metabolism Reviews, 2019, v. 51, n. 3, p. 247, doi. 10.1080/03602532.2019.1632888

By:

Schulz, Josefine;
Kluwe, Franziska;
Mikus, Gerd;
Michelet, Robin;
Kloft, Charlotte

Publication type:

Article

A minimal physiologically‐based pharmacokinetic modeling platform to predict intratumor exposure and receptor occupancy of an anti‐LAG‐3 monoclonal antibody.

Published in:

CPT: Pharmacometrics & Systems Pharmacology, 2025, v. 14, n. 3, p. 460, doi. 10.1002/psp4.13285

By:

Michelet, Robin;
Petersson, Klas;
Huisman, Marc C.;
Menke‐van der Houven van Oordt, C. Willemien;
Miedema, Iris H. C.;
Thiele, Andrea;
Montaseri, Ghazal;
Pérez‐Pitarch, Alejandro;
Busse, David

Publication type:

Article

Barriers to global pharmacometrics: educational challenges and opportunities across the globe.

Published in:

CPT: Pharmacometrics & Systems Pharmacology, 2023, v. 12, n. 6, p. 743, doi. 10.1002/psp4.12940

By:

Michelet, Robin;
Aulin, Linda B. S.;
Borghardt, Jens M.;
Costa, Teresa Dalla;
Denti, Paolo;
Ibarra, Manuel;
Ma, Guangda;
Meibohm, Bernd;
Pillai, Goonaseelan;
Schmidt, Stephan;
Hennig, Stefanie;
Kloft, Charlotte

Publication type:

Article

Exploring the Impact of Developmental Clearance Saturation on Propylene Glycol Exposure in Adults and Term Neonates Using Physiologically Based Pharmacokinetic Modeling.

Published in:

Journal of Clinical Pharmacology, 2025, v. 65, n. 3, p. 272, doi. 10.1002/jcph.6150

By:

Olafuyi, Olusola;
Michelet, Robin;
Garle, Michael;
Allegaert, Karel

Publication type:

Article

Quantification of persister formation of Escherichia coli leveraging electronic cell counting and semi-mechanistic pharmacokinetic/pharmacodynamic modelling.

Published in:

2021

By:

Seeger, Johanna;
Michelet, Robin;
Kloft, Charlotte

Publication type:

journal article

Pharmacokinetic/Pharmacodynamic Evaluation of Hydrocortisone Therapy in Pediatric Patients with Congenital Adrenal Hyperplasia.

Published in:

2020

By:

Melin, Johanna;
Parra-Guillen, Zinnia P;
Michelet, Robin;
Truong, Thi;
Huisinga, Wilhelm;
Hartung, Niklas;
Hindmarsh, Peter;
Kloft, Charlotte

Publication type:

journal article