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Blockers of Skeletal Muscle Na v 1.4 Channels: From Therapy of Myotonic Syndrome to Molecular Determinants of Pharmacological Action and Back.
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- International Journal of Molecular Sciences, 2023, v. 24, n. 1, p. 857, doi. 10.3390/ijms24010857
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- Article
Statin-Induced Myopathy: Translational Studies from Preclinical to Clinical Evidence.
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- International Journal of Molecular Sciences, 2021, v. 22, n. 4, p. 2070, doi. 10.3390/ijms22042070
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- Article
Increased rigidity of the chiral centre of tocainide favours stereoselectivity and use-dependent block of skeletal muscle Na<sup>+</sup> channels enhancing the antimyotonic activity in vivo.
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- British Journal of Pharmacology, 2001, v. 134, n. 7, p. 1523, doi. 10.1038/sj.bjp.0704366
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- Article
Synthesis of beta-proline like derivatives and their evaluation as sodium channel blockers.
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- Journal of Heterocyclic Chemistry, 2007, v. 44, n. 5, p. 1099, doi. 10.1002/jhet.5570440519
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- Article
In vivo longitudinal study of rodent skeletal muscle atrophy using ultrasonography.
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- Scientific Reports, 2016, p. 20061, doi. 10.1038/srep20061
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- Article
Effects of Nandrolone in the Counteraction of Skeletal Muscle Atrophy in a Mouse Model of Muscle Disuse: Molecular Biology and Functional Evaluation.
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- PLoS ONE, 2015, v. 10, n. 6, p. 1, doi. 10.1371/journal.pone.0129686
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- Article
Effects of Pleiotrophin Overexpression on Mouse Skeletal Muscles in Normal Loading and in Actual and Simulated Microgravity.
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- PLoS ONE, 2013, v. 8, n. 8, p. 1, doi. 10.1371/journal.pone.0072028
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- Article
Paracrine Effects of IGF-1 Overexpression on the Functional Decline Due to Skeletal Muscle Disuse: Molecular and Functional Evaluation in Hindlimb Unloaded MLC/mIgf-1 Transgenic Mice.
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- PLoS ONE, 2013, v. 8, n. 6, p. 1, doi. 10.1371/journal.pone.0065167
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- Article
Synthesis and in vitro sodium channel blocking activity evaluation of novel homochiral mexiletine analogs.
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- Chirality, 2010, v. 22, n. 3, p. 299, doi. 10.1002/chir.20741
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- Article
β-Dystroglycan Restoration and Pathology Progression in the Dystrophic mdx Mouse: Outcome and Implication of a Clinically Oriented Study with a Novel Oral Dasatinib Formulation.
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- Biomolecules (2218-273X), 2021, v. 11, n. 11, p. 1742, doi. 10.3390/biom11111742
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- Article
Inhibition of skeletal muscle sodium currents by mexiletine analogues: specific hydrophobic interactions rather than lipophilia per se account for drug therapeutic profile.
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- Naunyn-Schmiedeberg's Archives of Pharmacology, 2003, v. 367, n. 3, p. 318, doi. 10.1007/s00210-002-0669-0
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- Article
Growth hormone secretagogues modulate inflammation and fibrosis in mdx mouse model of Duchenne muscular dystrophy.
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- Frontiers in Immunology, 2023, v. 14, p. 1, doi. 10.3389/fimmu.2023.1119888
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- Article
Change of chloride ion channel conductance is an early event of slow‐to‐fast fibre type transition during unloading‐induced muscle disuse.
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- Brain: A Journal of Neurology, 2002, v. 125, n. 7, p. 1510, doi. 10.1093/brain/awf162
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- Article
Ryanodine channel complex stabilizer compound S48168/ARM210 as a disease modifier in dystrophin-deficient mdx mice: proof-of-concept study and independent validation of efficacy.
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- FASEB Journal, 2018, v. 32, n. 2, p. 1025, doi. 10.1096/fj.201700182RRR
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Therapeutic Approaches to Genetic Ion Channelopathies and Perspectives in Drug Discovery.
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- Frontiers in Pharmacology, 2016, p. 1, doi. 10.3389/fphar.2016.00121
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- Article
Dual Action of Mexiletine and Its Pyrroline Derivatives as Skeletal Muscle Sodium Channel Blockers and Anti-oxidant Compounds: Toward Novel Therapeutic Potential.
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- Frontiers in Pharmacology, 2018, p. 1, doi. 10.3389/fphar.2017.00907
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- Article
Stereospecific synthesis of para-hydroxymexiletine and sodium channel blocking activity evaluation.
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- Chirality, 2004, v. 16, n. 2, p. 72
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- Article
Elucidating the Contribution of Skeletal Muscle Ion Channels to Amyotrophic Lateral Sclerosis in search of new therapeutic options.
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- Scientific Reports, 2019, v. 9, n. 1, p. 1, doi. 10.1038/s41598-019-39676-3
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- Article
Growth hormone secretagogues prevent dysregulation of skeletal muscle calcium homeostasis in a rat model of cisplatin-induced cachexia.
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- Journal of Cachexia, Sarcopenia & Muscle, 2017, v. 8, n. 3, p. 386, doi. 10.1002/jcsm.12185
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- Article
On the Metabolically Active Form of Metaglidasen: Improved Synthesis and Investigation of Its Peculiar Activity on Peroxisome Proliferator-Activated Receptors and Skeletal Muscles.
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- ChemMedChem, 2015, v. 10, n. 3, p. 555, doi. 10.1002/cmdc.201402462
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Branched-Chain Amino Acids and Di-Alanine Supplementation in Aged Mice: A Translational Study on Sarcopenia.
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- Nutrients, 2023, v. 15, n. 2, p. 330, doi. 10.3390/nu15020330
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Ergogenic Effect of BCAAs and L-Alanine Supplementation: Proof-of-Concept Study in a Murine Model of Physiological Exercise.
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- Nutrients, 2020, v. 12, n. 8, p. 2295, doi. 10.3390/nu12082295
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- Article