Works by Michel Kranendonk

Results: 25

The Adaptation of MCF-7 Breast Cancer Spheroids to the Chemotherapeutic Doxorubicin: The Dynamic Role of Phase I Drug Metabolizing Enzymes.

Published in:

Metabolites (2218-1989), 2025, v. 15, n. 2, p. 136, doi. 10.3390/metabo15020136

By:

Crispim, Daniel;
Ramos, Carolina;
Esteves, Francisco;
Kranendonk, Michel

Publication type:

Article

Corrigendum: The Role of the FMN-Domain of Human Cytochrome P450 Oxidoreductase in Its Promiscuous Interactions With Structurally Diverse Redox Partners.

Published in:

2020

By:

Esteves, Francisco;
Campelo, Diana;
Gomes, Bruno Costa;
Urban, Philippe;
Bozonnet, Sophie;
Lautier, Thomas;
Rueff, José;
Truan, Gilles;
Kranendonk, Michel

Publication type:

Correction Notice

The Role of the FMN-Domain of Human Cytochrome P450 Oxidoreductase in Its Promiscuous Interactions With Structurally Diverse Redox Partners.

Published in:

Frontiers in Pharmacology, 2020, v. 11, p. 1, doi. 10.3389/fphar.2020.00299

By:

Esteves, Francisco;
Campelo, Diana;
Gomes, Bruno Costa;
Urban, Philippe;
Bozonnet, Sophie;
Lautier, Thomas;
Rueff, José;
Truan, Gilles;
Kranendonk, Michel

Publication type:

Article

The Complex Dynamic of Phase I Drug Metabolism in the Early Stages of Doxorubicin Resistance in Breast Cancer Cells.

Published in:

Genes, 2022, v. 13, n. 11, p. 1977, doi. 10.3390/genes13111977

By:

Barata, Isabel S.;
Gomes, Bruno C.;
Rodrigues, António S.;
Rueff, José;
Kranendonk, Michel;
Esteves, Francisco

Publication type:

Article

Evaluation of the cyto- and genotoxicity of two types of cellulose nanomaterials using human intestinal cells and in vitro digestion simulation.

Published in:

Archives of Toxicology, 2025, v. 99, n. 2, p. 575, doi. 10.1007/s00204-024-03911-2

By:

Vital, Nádia;
Cardoso, Maria;
Kranendonk, Michel;
Silva, Maria João;
Louro, Henriqueta

Publication type:

Article

The stimulatory role of human cytochrome b5 in the bioactivation activities of human CYP1A2, 2A6 and 2E1: a new cell expression system to study cytochrome P450-mediated biotransformation (a corrigendum report on Duarte et al. (2005) Mutagenesis 20, 93–100)

Published in:

Mutagenesis, 2007, v. 22, n. 1, p. 75

By:

Maria Paula Duarte;
Bernardo Brito Palma;
Andrei A. Gilep;
António Laires;
José Santos Oliveira;
Sergey A. Usanov;
José Rueff;
Michel Kranendonk

Publication type:

Article

Genotoxicity and endoreduplication inducing activity of the food flavouring eugenol.

Published in:

Mutagenesis, 2006, v. 21, n. 3, p. 199, doi. 10.1093/mutage/gel017

By:

Alexandra Maralhas;
Ana Monteiro;
Célia Martins;
Michel Kranendonk;
António Laires;
José Rueff;
António S. Rodrigues

Publication type:

Article

Escherichia coli BTC, a human cytochrome P450 competent tester strain with a high sensitivity towards alkylating agents: involvement of alkyltransferases in the repair of DNA damage induced by aromatic amines.

Published in:

Mutagenesis, 2005, v. 20, n. 3, p. 199, doi. 10.1093/mutage/gei028

By:

Maria Paula Duarte;
Bernardo Brito Palma;
Antnio Laires;
Jos Santos Oliveira;
Jos Rueff;
Michel Kranendonk

Publication type:

Article

The stimulatory role of human cytochrome b5 in the bioactivation activities of human CYP1A2, 2A6 and 2E1: a new cell expression system to study cytochrome P450 mediated biotransformation.

Published in:

Mutagenesis, 2005, v. 20, n. 2, p. 93, doi. 10.1093/mutage/gei012

By:

Maria Paula Duarte;
Bernardo Brito Palma;
Andrei A. Gilep;
Antnio Laires;
Jos Santos Oliveira;
Sergey A. Usanov;
Jos Rueff;
Michel Kranendonk

Publication type:

Article

Challenges of the Application of In Vitro Digestion for Nanomaterials Safety Assessment.

Published in:

Foods, 2024, v. 13, n. 11, p. 1690, doi. 10.3390/foods13111690

By:

Vital, Nádia;
Gramacho, Ana Catarina;
Silva, Mafalda;
Cardoso, Maria;
Alvito, Paula;
Kranendonk, Michel;
Silva, Maria João;
Louro, Henriqueta

Publication type:

Article

Toxicological Assessment of Cellulose Nanomaterials: Oral Exposure.

Published in:

Nanomaterials (2079-4991), 2022, v. 12, n. 19, p. 3375, doi. 10.3390/nano12193375

By:

Vital, Nádia;
Ventura, Célia;
Kranendonk, Michel;
Silva, Maria João;
Louro, Henriqueta

Publication type:

Article

Front Cover: Electrochemical Activity of Cytochrome P450 1A2: The Relevance of O2 Control and the Natural Electron Donor (ChemElectroChem 3/2021).

Published in:

ChemElectroChem, 2021, v. 8, n. 3, p. 425, doi. 10.1002/celc.202001616

By:

Silveira, Célia M.;
Rodrigues, Patrícia R.;
Ghach, Wissam;
Pereira, Sofia A.;
Esteves, Francisco;
Kranendonk, Michel;
Etienne, Mathieu;
Almeida, M. Gabriela

Publication type:

Article

Electrochemical Activity of Cytochrome P450 1A2: The Relevance of O2 Control and the Natural Electron Donor.

Published in:

ChemElectroChem, 2021, v. 8, n. 3, p. 430, doi. 10.1002/celc.202001615

By:

Silveira, Célia M.;
Rodrigues, Patrícia R.;
Ghach, Wissam;
Pereira, Sofia A.;
Esteves, Francisco;
Kranendonk, Michel;
Etienne, Mathieu;
Almeida, M. Gabriela

Publication type:

Article

Electrochemical Activity of Cytochrome P450 1A2: The Relevance of O2 Control and the Natural Electron Donor.

Published in:

ChemElectroChem, 2021, v. 8, n. 3, p. 500, doi. 10.1002/celc.202001255

By:

Silveira, Célia M.;
Rodrigues, Patrícia R.;
Ghach, Wissam;
Pereira, Sofia A.;
Esteves, Francisco;
Kranendonk, Michel;
Etienne, Mathieu;
Almeida, M. Gabriela

Publication type:

Article

Single Mutations in Cytochrome P450 Oxidoreductase Can Alter the Specificity of Human Cytochrome P450 1A2-Mediated Caffeine Metabolism.

Published in:

Biomolecules (2218-273X), 2023, v. 13, n. 7, p. 1083, doi. 10.3390/biom13071083

By:

Esteves, Francisco;
Almeida, Cristina M. M.;
Silva, Sofia;
Saldanha, Inês;
Urban, Philippe;
Rueff, José;
Pompon, Denis;
Truan, Gilles;
Kranendonk, Michel

Publication type:

Article

Correction: The Hinge Segment of Human NADPH-Cytochrome P450 Reductase in Conformational Switching: The Critical Role of Ionic Strength.

Published in:

2018

By:

Campelo, Diana;
Lautier, Thomas;
Urban, Philippe;
Esteves, Francisco;
Bozonnet, Sophie;
Truan, Gilles;
Kranendonk, Michel

Publication type:

Correction Notice

Editorial: Role of Protein-Protein Interactions in Metabolism: Genetics, Structure, Function.

Published in:

Frontiers in Pharmacology, 2017, p. 1, doi. 10.3389/fphar.2017.00881

By:

Pandey, Amit V.;
Henderson, Colin J.;
Yuji Ishii;
Kranendonk, Michel;
Backes, Wayne L.;
Zanger, Ulrich M.

Publication type:

Article

The Hinge Segment of Human NADPH-Cytochrome P450 Reductase in Conformational Switching: The Critical Role of Ionic Strength.

Published in:

Frontiers in Pharmacology, 2017, p. 1, doi. 10.3389/fphar.2017.00755

By:

Campelo, Diana;
Lautier, Thomas;
Urban, Philippe;
Esteves, Francisco;
Bozonnet, Sophie;
Truan, Gilles;
Kranendonk, Michel

Publication type:

Article

Interaction Modes of Microsomal Cytochrome P450s with Its Reductase and the Role of Substrate Binding.

Published in:

International Journal of Molecular Sciences, 2020, v. 21, n. 18, p. 6669, doi. 10.3390/ijms21186669

By:

Esteves, Francisco;
Urban, Philippe;
Rueff, José;
Truan, Gilles;
Kranendonk, Michel

Publication type:

Article

Probing the Role of the Hinge Segment of Cytochrome P450 Oxidoreductase in the Interaction with Cytochrome P450.

Published in:

International Journal of Molecular Sciences, 2018, v. 19, n. 12, p. 3914, doi. 10.3390/ijms19123914

By:

Campelo, Diana;
Esteves, Francisco;
Brito Palma, Bernardo;
Costa Gomes, Bruno;
Rueff, José;
Lautier, Thomas;
Urban, Philippe;
Truan, Gilles;
Kranendonk, Michel

Publication type:

Article

Heterologous expression of xenobiotic mammalian-metabolizing enzymesin mutagenicity tester bacteria: an update and practical considerations

Published in:

Critical Reviews in Toxicology, 2000, v. 30, n. 3, p. 287

By:

Estabrook, Ronald W.;
Vermeulen, Nico P. E.;
Rueff, Jose;
Kranendonk, Michel;
Laires, Antonio

Publication type:

Article

Accurate Determination of Human CPR Conformational Equilibrium by smFRET Using Dual Orthogonal Noncanonical Amino Acid Labeling.

Published in:

ChemBioChem, 2019, v. 20, n. 5, p. 659, doi. 10.1002/cbic.201800607

By:

Quast, Robert B.;
Fatemi, Fataneh;
Kranendonk, Michel;
Margeat, Emmanuel;
Truan, Gilles

Publication type:

Article

Corrigendum: The Role of the FMN-Domain of Human Cytochrome P450 Oxidoreductase in Its Promiscuous Interactions With Structurally Diverse Redox Partners.

Published in:

2020

By:

Esteves, Francisco;
Campelo, Diana;
Gomes, Bruno Costa;
Urban, Philippe;
Bozonnet, Sophie;
Lautier, Thomas;
Rueff, José;
Truan, Gilles;
Kranendonk, Michel

Publication type:

Correction Notice

Pleiotropy of Progesterone Receptor Membrane Component 1 in Modulation of Cytochrome P450 Activity †.

Published in:

Journal of Xenobiotics, 2024, v. 14, n. 2, p. 575, doi. 10.3390/jox14020034

By:

Barata, Isabel S.;
Rueff, José;
Kranendonk, Michel;
Esteves, Francisco

Publication type:

Article

The Central Role of Cytochrome P450 in Xenobiotic Metabolism--A Brief Review on a Fascinating Enzyme Family.

Published in:

Journal of Xenobiotics, 2021, v. 11, n. 3, p. 94, doi. 10.3390/jox11030007

By:

Esteves, Francisco;
Rueff, José;
Kranendonk, Michel

Publication type:

Article

Works by Michel Kranendonk

The Adaptation of MCF-7 Breast Cancer Spheroids to the Chemotherapeutic Doxorubicin: The Dynamic Role of Phase I Drug Metabolizing Enzymes.

Corrigendum: The Role of the FMN-Domain of Human Cytochrome P450 Oxidoreductase in Its Promiscuous Interactions With Structurally Diverse Redox Partners.

The Role of the FMN-Domain of Human Cytochrome P450 Oxidoreductase in Its Promiscuous Interactions With Structurally Diverse Redox Partners.

The Complex Dynamic of Phase I Drug Metabolism in the Early Stages of Doxorubicin Resistance in Breast Cancer Cells.

Evaluation of the cyto- and genotoxicity of two types of cellulose nanomaterials using human intestinal cells and in vitro digestion simulation.

The stimulatory role of human cytochrome b5 in the bioactivation activities of human CYP1A2, 2A6 and 2E1: a new cell expression system to study cytochrome P450-mediated biotransformation (a corrigendum report on Duarte et al. (2005) Mutagenesis 20, 93–100)

Genotoxicity and endoreduplication inducing activity of the food flavouring eugenol.

Escherichia coli BTC, a human cytochrome P450 competent tester strain with a high sensitivity towards alkylating agents: involvement of alkyltransferases in the repair of DNA damage induced by aromatic amines.

The stimulatory role of human cytochrome b5 in the bioactivation activities of human CYP1A2, 2A6 and 2E1: a new cell expression system to study cytochrome P450 mediated biotransformation.

Challenges of the Application of In Vitro Digestion for Nanomaterials Safety Assessment.

Toxicological Assessment of Cellulose Nanomaterials: Oral Exposure.

Front Cover: Electrochemical Activity of Cytochrome P450 1A2: The Relevance of O<sub>2</sub> Control and the Natural Electron Donor (ChemElectroChem 3/2021).

Electrochemical Activity of Cytochrome P450 1A2: The Relevance of O<sub>2</sub> Control and the Natural Electron Donor.

Electrochemical Activity of Cytochrome P450 1A2: The Relevance of O<sub>2</sub> Control and the Natural Electron Donor.

Single Mutations in Cytochrome P450 Oxidoreductase Can Alter the Specificity of Human Cytochrome P450 1A2-Mediated Caffeine Metabolism.

Correction: The Hinge Segment of Human NADPH-Cytochrome P450 Reductase in Conformational Switching: The Critical Role of Ionic Strength.

Editorial: Role of Protein-Protein Interactions in Metabolism: Genetics, Structure, Function.

The Hinge Segment of Human NADPH-Cytochrome P450 Reductase in Conformational Switching: The Critical Role of Ionic Strength.

Interaction Modes of Microsomal Cytochrome P450s with Its Reductase and the Role of Substrate Binding.

Probing the Role of the Hinge Segment of Cytochrome P450 Oxidoreductase in the Interaction with Cytochrome P450.

Heterologous expression of xenobiotic mammalian-metabolizing enzymesin mutagenicity tester bacteria: an update and practical considerations

Accurate Determination of Human CPR Conformational Equilibrium by smFRET Using Dual Orthogonal Noncanonical Amino Acid Labeling.

Corrigendum: The Role of the FMN-Domain of Human Cytochrome P450 Oxidoreductase in Its Promiscuous Interactions With Structurally Diverse Redox Partners.

Pleiotropy of Progesterone Receptor Membrane Component 1 in Modulation of Cytochrome P450 Activity †.

The Central Role of Cytochrome P450 in Xenobiotic Metabolism--A Brief Review on a Fascinating Enzyme Family.