Works by Michailidou, Kyriaki

Results: 110
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    Chromatin interactome mapping at 139 independent breast cancer risk signals.

    Published in:
    Genome Biology, 2020, v. 21, n. 1, p. 1, doi. 10.1186/s13059-019-1877-y
    By:
    • Beesley, Jonathan;
    • Sivakumaran, Haran;
    • Moradi Marjaneh, Mahdi;
    • Lima, Luize G.;
    • Hillman, Kristine M.;
    • Kaufmann, Susanne;
    • Tuano, Natasha;
    • Hussein, Nehal;
    • Ham, Sunyoung;
    • Mukhopadhyay, Pamela;
    • Kazakoff, Stephen;
    • Lee, Jason S.;
    • Michailidou, Kyriaki;
    • Barnes, Daniel R.;
    • Antoniou, Antonis C.;
    • Fachal, Laura;
    • Dunning, Alison M.;
    • Easton, Douglas F.;
    • Waddell, Nicola;
    • Rosenbluh, Joseph
    Publication type:
    Article
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    The International Hemoglobinopathy Research Network (INHERENT): An international initiative to study the role of genetic modifiers in hemoglobinopathies.

    Published in:
    American Journal of Hematology, 2021, v. 96, n. 11, p. E416, doi. 10.1002/ajh.26323
    By:
    • Kountouris, Petros;
    • Stephanou, Coralea;
    • Archer, Natasha;
    • Bonifazi, Fedele;
    • Giannuzzi, Viviana;
    • Kuo, Kevin H. M.;
    • Maggio, Aurelio;
    • Makani, Julie;
    • Mañú‐Pereira, María del Mar;
    • Michailidou, Kyriaki;
    • Nkya, Siana;
    • Nnodu, Obiageli E.;
    • Trompeter, Sara;
    • Tshilolo, Léon;
    • Wonkam, Ambroise;
    • Zilfalil, Bin Alwi;
    • Inusa, Baba P. D.;
    • Kleanthous, Marina
    Publication type:
    Article
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    Genome-wide association analysis identifies three new breast cancer susceptibility loci.

    Published in:
    Nature Genetics, 2012, v. 44, n. 3, p. 312, doi. 10.1038/ng.1049
    By:
    • Ghoussaini, Maya;
    • Fletcher, Olivia;
    • Michailidou, Kyriaki;
    • Turnbull, Clare;
    • Schmidt, Marjanka K;
    • Dicks, Ed;
    • Dennis, Joe;
    • Wang, Qin;
    • Humphreys, Manjeet K;
    • Luccarini, Craig;
    • Baynes, Caroline;
    • Conroy, Don;
    • Maranian, Melanie;
    • Ahmed, Shahana;
    • Driver, Kristy;
    • Johnson, Nichola;
    • Orr, Nicholas;
    • dos Santos Silva, Isabel;
    • Waisfisz, Quinten;
    • Meijers-Heijboer, Hanne
    Publication type:
    Article
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    Genetically Predicted Body Mass Index and Breast Cancer Risk: Mendelian Randomization Analyses of Data from 145,000 Women of European Descent.

    Published in:
    2016
    By:
    • Guo, Yan;
    • Warren Andersen, Shaneda;
    • Shu, Xiao-Ou;
    • Michailidou, Kyriaki;
    • Bolla, Manjeet K.;
    • Wang, Qin;
    • Garcia-Closas, Montserrat;
    • Milne, Roger L.;
    • Schmidt, Marjanka K.;
    • Chang-Claude, Jenny;
    • Dunning, Allison;
    • Bojesen, Stig E.;
    • Ahsan, Habibul;
    • Aittomäki, Kristiina;
    • Andrulis, Irene L.;
    • Anton-Culver, Hoda;
    • Arndt, Volker;
    • Beckmann, Matthias W.;
    • Beeghly-Fadiel, Alicia;
    • Benitez, Javier
    Publication type:
    journal article
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    Challenges and approaches to calibrating patient phenotype as evidence for cancer gene variant classification under ACMG/AMP guidelines.

    Published in:
    Human Molecular Genetics, 2024, v. 33, n. 8, p. 724, doi. 10.1093/hmg/ddae009
    By:
    • Fortuno, Cristina;
    • Michailidou, Kyriaki;
    • Parsons, Michael;
    • Dolinsky, Jill S;
    • Pesaran, Tina;
    • Yussuf, Amal;
    • Mester, Jessica L;
    • Hruska, Kathleen S;
    • Hiraki, Susan;
    • O'Connor, Robert;
    • Chan, Raymond C;
    • Kim, Serra;
    • Tavtigian, Sean V;
    • Goldgar, David;
    • James, Paul A;
    • Spurdle, Amanda B
    Publication type:
    Article
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    Fine-Mapping of the 1p11.2 Breast Cancer Susceptibility Locus.

    Published in:
    PLoS ONE, 2016, v. 11, n. 8, p. 1, doi. 10.1371/journal.pone.0160316
    By:
    • Horne, Hisani N.;
    • Chung, Charles C.;
    • Zhang, Han;
    • Yu, Kai;
    • Prokunina-Olsson, Ludmila;
    • Michailidou, Kyriaki;
    • Bolla, Manjeet K.;
    • Wang, Qin;
    • Dennis, Joe;
    • Hopper, John L.;
    • Southey, Melissa C.;
    • Schmidt, Marjanka K.;
    • Broeks, Annegien;
    • Muir, Kenneth;
    • Lophatananon, Artitaya;
    • Fasching, Peter A.;
    • Beckmann, Matthias W.;
    • Fletcher, Olivia;
    • Johnson, Nichola;
    • Sawyer, Elinor J.
    Publication type:
    Article
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    RAD51B in Familial Breast Cancer.

    Published in:
    PLoS ONE, 2016, v. 11, n. 5, p. 1, doi. 10.1371/journal.pone.0153788
    By:
    • Pelttari, Liisa M.;
    • Khan, Sofia;
    • Vuorela, Mikko;
    • Kiiski, Johanna I.;
    • Vilske, Sara;
    • Nevanlinna, Viivi;
    • Ranta, Salla;
    • Schleutker, Johanna;
    • Winqvist, Robert;
    • Kallioniemi, Anne;
    • Dörk, Thilo;
    • Bogdanova, Natalia V.;
    • Figueroa, Jonine;
    • Pharoah, Paul D. P.;
    • Schmidt, Marjanka K.;
    • Dunning, Alison M.;
    • García-Closas, Montserrat;
    • Bolla, Manjeet K.;
    • Dennis, Joe;
    • Michailidou, Kyriaki
    Publication type:
    Article
    24

    Genome-wide association analysis of more than 120,000 individuals identifies 15 new susceptibility loci for breast cancer.

    Published in:
    Nature Genetics, 2015, v. 47, n. 4, p. 373, doi. 10.1038/ng.3242
    By:
    • Michailidou, Kyriaki;
    • Dennis, Joe;
    • Lush, Michael J;
    • Bolla, Manjeet K;
    • Wang, Qin;
    • Rahman, Nazneen;
    • Turnbull, Clare;
    • Schoemaker, Minouk J;
    • Muir, Kenneth;
    • Lophatananon, Artitaya;
    • Stewart-Brown, Sarah;
    • Siriwanarangsan, Pornthep;
    • Hartman, Mikael;
    • Miao, Hui;
    • Chia, Kee Seng;
    • Chan, Ching Wan;
    • Fasching, Peter A;
    • Hein, Alexander;
    • Beckmann, Matthias W;
    • Haeberle, Lothar
    Publication type:
    Article
    25

    Large-scale genotyping identifies 41 new loci associated with breast cancer risk.

    Published in:
    Nature Genetics, 2013, v. 45, n. 4, p. 353, doi. 10.1038/ng.2563
    By:
    • Michailidou, Kyriaki;
    • Turnbull, Clare;
    • Rahman, Nazneen;
    • Swerdlow, Anthony;
    • Jones, Michael;
    • Edge, Stephen;
    • Fostira, Florentia;
    • Kang, Daehee;
    • Yoo, Keun-Young;
    • Noh, Dong-Young;
    • Matsuo, Keitaro;
    • Ito, Hidemi;
    • Sueta, Aiko;
    • Iwata, Hiroji;
    • Shu, Xiao-Ou;
    • Cai, Hui;
    • Cai, Qiuyin;
    • Zheng, Wei;
    • Deming-Halverson, Sandra;
    • Shrubsole, Martha
    Publication type:
    Article
    26

    Rare germline copy number variants (CNVs) and breast cancer risk.

    Published in:
    Communications Biology, 2022, v. 5, n. 1, p. 1, doi. 10.1038/s42003-021-02990-6
    By:
    • Dennis, Joe;
    • Tyrer, Jonathan P.;
    • Walker, Logan C.;
    • Michailidou, Kyriaki;
    • Dorling, Leila;
    • Bolla, Manjeet K.;
    • Wang, Qin;
    • Ahearn, Thomas U.;
    • Andrulis, Irene L.;
    • Anton-Culver, Hoda;
    • Antonenkova, Natalia N.;
    • Arndt, Volker;
    • Aronson, Kristan J.;
    • Freeman, Laura E. Beane;
    • Beckmann, Matthias W.;
    • Behrens, Sabine;
    • Benitez, Javier;
    • Bermisheva, Marina;
    • Bogdanova, Natalia V.;
    • Bojesen, Stig E.
    Publication type:
    Article
    27

    Polygenic risk scores stratify breast cancer risk among women with benign breast disease.

    Published in:
    JNCI: Journal of the National Cancer Institute, 2025, v. 117, n. 3, p. 456, doi. 10.1093/jnci/djae255
    By:
    • Sherman, Mark E;
    • Winham, Stacey J;
    • Vierkant, Robert A;
    • McCauley, Bryan M;
    • Scott, Christopher G;
    • Schrup, Sarah;
    • Gaudet, Mia M;
    • Troester, Melissa A;
    • Pruthi, Sandhya;
    • Radisky, Derek C;
    • Degnim, Amy C;
    • Couch, Fergus J;
    • Bolla, Manjeet K;
    • Wang, Qin;
    • Dennis, Joe;
    • Michailidou, Kyriaki;
    • Guenel, Pascal;
    • Truong, Therese;
    • Chang-Claude, Jenny;
    • Obi, Nadia
    Publication type:
    Article
    28

    A Mendelian randomization analysis of circulating lipid traits and breast cancer risk.

    Published in:
    2020
    By:
    • Beeghly-Fadiel, Alicia;
    • Khankari, Nikhil K;
    • Delahanty, Ryan J;
    • Shu, Xiao-Ou;
    • Lu, Yingchang;
    • Schmidt, Marjanka K;
    • Bolla, Manjeet K;
    • Michailidou, Kyriaki;
    • Wang, Qin;
    • Dennis, Joe;
    • Yannoukakos, Drakoulis;
    • Dunning, Alison M;
    • Pharoah, Paul D P;
    • Chenevix-Trench, Georgia;
    • Milne, Roger L;
    • Hunter, David J;
    • Per, Hall;
    • Kraft, Peter;
    • Simard, Jacques;
    • Easton, Douglas F
    Publication type:
    journal article
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    Assessment of interactions between 205 breast cancer susceptibility loci and 13 established risk factors in relation to breast cancer risk, in the Breast Cancer Association Consortium.

    Published in:
    2020
    By:
    • Kapoor, Pooja Middha;
    • Lindström, Sara;
    • Behrens, Sabine;
    • Wang, Xiaoliang;
    • Michailidou, Kyriaki;
    • Bolla, Manjeet K;
    • Wang, Qin;
    • Dennis, Joe;
    • Dunning, Alison M;
    • Pharoah, Paul D P;
    • Schmidt, Marjanka K;
    • Kraft, Peter;
    • García-Closas, Montserrat;
    • Easton, Douglas F;
    • Milne, Roger L;
    • Chang-Claude, Jenny;
    • Consortium, on behalf of Breast Cancer Association;
    • Breast Cancer Association Consortium
    Publication type:
    journal article
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    Associations of obesity and circulating insulin and glucose with breast cancer risk: a Mendelian randomization analysis.

    Published in:
    International Journal of Epidemiology, 2019, v. 48, n. 3, p. 795, doi. 10.1093/ije/dyy201
    By:
    • Shu, Xiang;
    • Wu, Lang;
    • Khankari, Nikhil K;
    • Shu, Xiao-Ou;
    • Wang, Thomas J;
    • Michailidou, Kyriaki;
    • Bolla, Manjeet K;
    • Wang, Qin;
    • Dennis, Joe;
    • Milne, Roger L;
    • Schmidt, Marjanka K;
    • Pharoah, Paul D P;
    • Andrulis, Irene L;
    • Hunter, David J;
    • Simard, Jacques;
    • Easton, Douglas F;
    • Zheng, Wei;
    • Consortium, Breast Cancer Association
    Publication type:
    Article
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    Joint associations of a polygenic risk score and environmental risk factors for breast cancer in the Breast Cancer Association Consortium.

    Published in:
    2018
    By:
    • Rudolph, Anja;
    • Song, Minsun;
    • Brook, Mark N;
    • Milne, Roger L;
    • Mavaddat, Nasim;
    • Michailidou, Kyriaki;
    • Bolla, Manjeet K;
    • Wang, Qin;
    • Dennis, Joe;
    • Wilcox, Amber N;
    • Hopper, John L;
    • Southey, Melissa C;
    • Keeman, Renske;
    • Fasching, Peter A;
    • Beckmann, Matthias W;
    • Gago-Dominguez, Manuela;
    • Castelao, Jose E;
    • Guénel, Pascal;
    • Truong, Thérèse;
    • Bojesen, Stig E
    Publication type:
    journal article
    34

    Mendelian randomization study of adiposity-related traits and risk of breast, ovarian, prostate, lung and colorectal cancer.

    Published in:
    2016
    By:
    • Chi Gao;
    • Patel, Chirag J.;
    • Kyriaki Michailidou;
    • Peters, Ulrike;
    • Jian Gong;
    • Schildkraut, Joellen;
    • Schumacher, Fredrick R.;
    • Wei Zheng;
    • Boffetta, Paolo;
    • Stucker, Isabelle;
    • Willett, Walter;
    • Gruber, Stephen;
    • Easton, Douglas F.;
    • Hunter, David J.;
    • Sellers, Thomas A.;
    • Haiman, Christopher;
    • Henderson, Brian E.;
    • Hung, Rayjean J.;
    • Amos, Christopher;
    • Pierce, Brandon L.
    Publication type:
    journal article
    35

    A genomic approach to therapeutic target validation identifies a glucose-lowering GLP1R variant protective for coronary heart disease.

    Published in:
    Science Translational Medicine, 2016, v. 8, n. 341, p. 1, doi. 10.1126/scitranslmed.aad3744
    By:
    • Scott, Robert A.;
    • Freitag, Daniel F.;
    • Li Li;
    • Chu, Audrey Y.;
    • Surendran, Praveen;
    • Young, Robin;
    • Grarup, Niels;
    • Stancáková, Alena;
    • Yuning Chen;
    • Varga, Tibor V.;
    • Yaghootkar, Hanieh;
    • Jian’an Luan;
    • Jing Hua Zhao;
    • Willems, Sara M.;
    • Wessel, Jennifer;
    • Shuai Wang;
    • Maruthur, Nisa;
    • Michailidou, Kyriaki;
    • Pirie, Ailith;
    • van der Lee, Sven J.
    Publication type:
    Article
    36

    Aggregation tests identify new gene associations with breast cancer in populations with diverse ancestry.

    Published in:
    Genome Medicine, 2023, v. 15, n. 1, p. 1, doi. 10.1186/s13073-022-01152-5
    By:
    • Mueller, Stefanie H.;
    • Lai, Alvina G.;
    • Valkovskaya, Maria;
    • Michailidou, Kyriaki;
    • Bolla, Manjeet K.;
    • Wang, Qin;
    • Dennis, Joe;
    • Lush, Michael;
    • Abu-Ful, Zomoruda;
    • Ahearn, Thomas U.;
    • Andrulis, Irene L.;
    • Anton-Culver, Hoda;
    • Antonenkova, Natalia N.;
    • Arndt, Volker;
    • Aronson, Kristan J.;
    • Augustinsson, Annelie;
    • Baert, Thais;
    • Freeman, Laura E. Beane;
    • Beckmann, Matthias W.;
    • Behrens, Sabine
    Publication type:
    Article
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    Pathogenic and Low-Frequency Variants in Children With Central Precocious Puberty.

    Published in:
    Frontiers in Endocrinology, 2021, v. 12, p. 1, doi. 10.3389/fendo.2021.745048
    By:
    • Neocleous, Vassos;
    • Fanis, Pavlos;
    • Toumba, Meropi;
    • Gorka, Barbara;
    • Kousiappa, Ioanna;
    • Tanteles, George A.;
    • Iasonides, Michalis;
    • Nicolaides, Nicolas C.;
    • Christou, Yiolanda P.;
    • Michailidou, Kyriaki;
    • Nicolaou, Stella;
    • Papacostas, Savvas S.;
    • Christoforidis, Athanasios;
    • Kyriakou, Andreas;
    • Vlachakis, Dimitrios;
    • Skordis, Nicos;
    • Phylactou, Leonidas A.
    Publication type:
    Article
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    Evaluation of associations between genetically predicted circulating protein biomarkers and breast cancer risk.

    Published in:
    International Journal of Cancer, 2020, v. 146, n. 8, p. 2130, doi. 10.1002/ijc.32542
    By:
    • Shu, Xiang;
    • Bao, Jiandong;
    • Wu, Lang;
    • Long, Jirong;
    • Shu, Xiao‐Ou;
    • Guo, Xingyi;
    • Yang, Yaohua;
    • Michailidou, Kyriaki;
    • Bolla, Manjeet K.;
    • Wang, Qin;
    • Dennis, Joe;
    • Andrulis, Irene L.;
    • Castelao, Jose E.;
    • Dörk, Thilo;
    • Gago‐Dominguez, Manuela;
    • García‐Closas, Montserrat;
    • Giles, Graham G.;
    • Lophatananon, Artitaya;
    • Muir, Kenneth;
    • Olsson, Håkan
    Publication type:
    Article
    45

    Fine-scale mapping of 8q24 locus identifies multiple independent risk variants for breast cancer.

    Published in:
    International Journal of Cancer, 2016, v. 139, n. 6, p. 1303, doi. 10.1002/ijc.30150
    By:
    • Shi, Jiajun;
    • Zhang, Yanfeng;
    • Zheng, Wei;
    • Michailidou, Kyriaki;
    • Ghoussaini, Maya;
    • Bolla, Manjeet K.;
    • Wang, Qin;
    • Dennis, Joe;
    • Lush, Michael;
    • Milne, Roger L.;
    • Shu, Xiao‐Ou;
    • Beesley, Jonathan;
    • Kar, Siddhartha;
    • Andrulis, Irene L.;
    • Anton‐Culver, Hoda;
    • Arndt, Volker;
    • Beckmann, Matthias W.;
    • Zhao, Zhiguo;
    • Guo, Xingyi;
    • Benitez, Javier
    Publication type:
    Article
    46

    Functional mechanisms underlying pleiotropic risk alleles at the 19p13.1 breast-ovarian cancer susceptibility locus.

    Published in:
    Nature Communications, 2016, v. 7, n. 9, p. 12675, doi. 10.1038/ncomms12675
    By:
    • Lawrenson, Kate;
    • Kar, Siddhartha;
    • McCue, Karen;
    • Kuchenbaeker, Karoline;
    • Michailidou, Kyriaki;
    • Tyrer, Jonathan;
    • Beesley, Jonathan;
    • Ramus, Susan J.;
    • Li, Qiyuan;
    • Delgado, Melissa K.;
    • Lee, Janet M.;
    • Aittomäki, Kristiina;
    • Andrulis, Irene L.;
    • Anton-Culver, Hoda;
    • Arndt, Volker;
    • Arun, Banu K.;
    • Arver, Brita;
    • Bandera, Elisa V.;
    • Barile, Monica;
    • Barkardottir, Rosa B.
    Publication type:
    Article
    47

    Identification of four novel susceptibility loci for oestrogen receptor negative breast cancer.

    Published in:
    Nature Communications, 2016, v. 7, n. 4, p. 11375, doi. 10.1038/ncomms11375
    By:
    • Couch, Fergus J.;
    • Kuchenbaecker, Karoline B.;
    • Michailidou, Kyriaki;
    • Mendoza-Fandino, Gustavo A.;
    • Nord, Silje;
    • Lilyquist, Janna;
    • Olswold, Curtis;
    • Hallberg, Emily;
    • Agata, Simona;
    • Ahsan, Habibul;
    • Aittomäki, Kristiina;
    • Ambrosone, Christine;
    • Andrulis, Irene L.;
    • Anton-Culver, Hoda;
    • Arndt, Volker;
    • Arun, Banu K.;
    • Arver, Brita;
    • Barile, Monica;
    • Barkardottir, Rosa B.;
    • Barrowdale, Daniel
    Publication type:
    Article
    48

    Evidence that breast cancer risk at the 2q35 locus is mediated through IGFBP5 regulation.

    Published in:
    Nature Communications, 2014, v. 5, n. 9, p. 4999, doi. 10.1038/ncomms5999
    By:
    • Ghoussaini, Maya;
    • Edwards, Stacey L.;
    • Michailidou, Kyriaki;
    • Nord, Silje;
    • Cowper-Sal·lari, Richard;
    • Desai, Kinjal;
    • Kar, Siddhartha;
    • Hillman, Kristine M.;
    • Kaufmann, Susanne;
    • Glubb, Dylan M.;
    • Beesley, Jonathan;
    • Dennis, Joe;
    • Bolla, Manjeet K.;
    • Wang, Qin;
    • Dicks, Ed;
    • Guo, Qi;
    • Schmidt, Marjanka K.;
    • Shah, Mitul;
    • Luben, Robert;
    • Brown, Judith
    Publication type:
    Article
    49

    2q36.3 is associated with prognosis for oestrogen receptor-negative breast cancer patients treated with chemotherapy.

    Published in:
    Nature Communications, 2014, v. 5, n. 6, p. 4051, doi. 10.1038/ncomms5051
    By:
    • Li, Jingmei;
    • Lindström, Linda S.;
    • Foo, Jia N.;
    • Rafiq, Sajjad;
    • Schmidt, Marjanka K.;
    • Pharoah, Paul D. P.;
    • Michailidou, Kyriaki;
    • Dennis, Joe;
    • Bolla, Manjeet K.;
    • Wang, Qin;
    • Van 't Veer, Laura J.;
    • Cornelissen, Sten;
    • Rutgers, Emiel;
    • Southey, Melissa C.;
    • Apicella, Carmel;
    • Dite, Gillian S.;
    • Hopper, John L.;
    • Fasching, Peter A.;
    • Haeberle, Lothar;
    • Ekici, Arif B.
    Publication type:
    Article
    50

    Mendelian randomisation study of smoking exposure in relation to breast cancer risk.

    Published in:
    2021
    By:
    • Park, Hanla A.;
    • Neumeyer, Sonja;
    • Michailidou, Kyriaki;
    • Bolla, Manjeet K.;
    • Wang, Qin;
    • Dennis, Joe;
    • Ahearn, Thomas U.;
    • Andrulis, Irene L.;
    • Anton-Culver, Hoda;
    • Antonenkova, Natalia N.;
    • Arndt, Volker;
    • Aronson, Kristan J.;
    • Augustinsson, Annelie;
    • Baten, Adinda;
    • Beane Freeman, Laura E.;
    • Becher, Heiko;
    • Beckmann, Matthias W.;
    • Behrens, Sabine;
    • Benitez, Javier;
    • Bermisheva, Marina
    Publication type:
    journal article