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Antipsychotic-induced hyponatraemia: a systematic review of the published evidence.
Published in:
2010
By:
- Meulendijks D;
- Mannesse CK;
- Jansen PA;
- van Marum RJ;
- Egberts TC;
- Meulendijks, Didier;
- Mannesse, Cyndie K;
- Jansen, Paul A F;
- van Marum, Rob J;
- Egberts, Toine C G
Publication type:
journal article
Trastuzumab and bevacizumab combined with docetaxel, oxaliplatin and capecitabine as first-line treatment of advanced HER2-positive gastric cancer: a multicenter phase II study.
Published in:
Investigational New Drugs, 2016, v. 34, n. 1, p. 119, doi. 10.1007/s10637-015-0309-4
By:
- Meulendijks, Didier;
- Beerepoot, Laurens;
- Boot, Henk;
- Groot, Jan;
- Los, Maartje;
- Boers, James;
- Vanhoutvin, Steven;
- Polee, Marco;
- Beeker, Aart;
- Portielje, Johanna;
- Jong, Robert;
- Goey, Swan;
- Kuiper, Maria;
- Sikorska, Karolina;
- Beijnen, Jos;
- Tesselaar, Margot;
- Schellens, Jan;
- Cats, Annemieke
Publication type:
Article
Haplotype structure defines effects of common DPYD variants c.85T > C (rs1801265) and c.496A > G (rs2297595) on dihydropyrimidine dehydrogenase activity: Implication for 5‐fluorouracil toxicity.
Published in:
British Journal of Clinical Pharmacology, 2021, v. 87, n. 8, p. 3234, doi. 10.1111/bcp.14742
By:
- Hamzic, Seid;
- Schärer, Dominic;
- Offer, Steven M.;
- Meulendijks, Didier;
- Nakas, Christos;
- Diasio, Robert B.;
- Fontana, Stefano;
- Wehrli, Marc;
- Schürch, Stefan;
- Amstutz, Ursula;
- Largiadèr, Carlo R.
Publication type:
Article
Food‐effect study on uracil and dihydrouracil plasma levels as marker for dihydropyrimidine dehydrogenase activity in human volunteers.
Published in:
British Journal of Clinical Pharmacology, 2018, v. 84, n. 12, p. 2761, doi. 10.1111/bcp.13719
By:
- Henricks, Linda M.;
- Jacobs, Bart A. W.;
- Meulendijks, Didier;
- Pluim, Dick;
- Broek, Daan;
- Vries, Niels;
- Rosing, Hilde;
- Beijnen, Jos H.;
- Huitema, Alwin D. R.;
- Guchelaar, Henk‐Jan;
- Cats, Annemieke;
- Schellens, Jan H. M.
Publication type:
Article
Pronounced between-subject and circadian variability in thymidylate synthase and dihydropyrimidine dehydrogenase enzyme activity in human volunteers.
Published in:
British Journal of Clinical Pharmacology, 2016, v. 82, n. 3, p. 706, doi. 10.1111/bcp.13007
By:
- Jacobs, Bart A. W.;
- Deenen, Maarten J.;
- Pluim, Dick;
- Hasselt, J. G. Coen;
- Krähenbühl, Martin D.;
- Geel, Robin M. J. M.;
- Vries, Niels;
- Rosing, Hilde;
- Meulendijks, Didier;
- Burylo, Artur M.;
- Cats, Annemieke;
- Beijnen, Jos H.;
- Huitema, Alwin D. R.;
- Schellens, Jan H. M.
Publication type:
Article
Comparison of toxicity and effectiveness between fixed-dose and body surface area-based dose capecitabine.
Published in:
Therapeutic Advances in Medical Oncology, 2019, v. 11, p. 1, doi. 10.1177/1758835919838964
By:
- de Man, Femke M.;
- Veerman, G.D. Marijn;
- Oomen-de Hoop, Esther;
- Deenen, Maarten J.;
- Meulendijks, Didier;
- Mandigers, Caroline M.P.W.;
- Soesan, Marcel;
- Schellens, Jan H.M.;
- van Meerten, Esther;
- van Gelder, Teun;
- Mathijssen, Ron H.J.
Publication type:
Article
Comparison of toxicity and effectiveness between fixed-dose and body surface area-based dose capecitabine.
Published in:
Therapeutic Advances in Medical Oncology, 2019, v. 11, p. N.PAG, doi. 10.1177/1758835919838964
By:
- de Man, Femke M.;
- Veerman, G.D. Marijn;
- Oomen-de Hoop, Esther;
- Deenen, Maarten J.;
- Meulendijks, Didier;
- Mandigers, Caroline M.P.W.;
- Soesan, Marcel;
- Schellens, Jan H.M.;
- van Meerten, Esther;
- van Gelder, Teun;
- Mathijssen, Ron H.J.
Publication type:
Article
Pretreatment serum uracil concentration as a predictor of severe and fatal fluoropyrimidine-associated toxicity.
Published in:
2017
By:
- Meulendijks, Didier;
- Henricks, Linda M;
- Jacobs, Bart A W;
- Aliev, Abidin;
- Deenen, Maarten J;
- de Vries, Niels;
- Rosing, Hilde;
- van Werkhoven, Erik;
- de Boer, Anthonius;
- Beijnen, Jos H;
- Mandigers, Caroline M P W;
- Soesan, Marcel;
- Cats, Annemieke;
- Schellens, Jan H M
Publication type:
journal article
A Nomogram to Predict Severe Toxicity in DPYD Wild‐Type Patients Treated With Capecitabine‐Based Anticancer Regimens.
Published in:
Clinical Pharmacology & Therapeutics, 2024, v. 115, n. 2, p. 269, doi. 10.1002/cpt.3100
By:
- Knikman, Jonathan E.;
- Lopez‐Yurda, Marta;
- Meulendijks, Didier;
- Deenen, Maarten J.;
- Schellens, Jan H.M.;
- Beijnen, Jos;
- Cats, Annemieke;
- Guchelaar, Henk‐Jan
Publication type:
Article
Response to "Plasma Uracil as a DPD Phenotyping Test: Pre‐analytical Handling Matters".
Published in:
Clinical Pharmacology & Therapeutics, 2023, v. 113, n. 3, p. 473, doi. 10.1002/cpt.2775
By:
- de With, Mirjam;
- Knikman, Jonathan;
- Schellens, Jan H. M.;
- Gelderblom, Hans;
- Cats, Annemieke;
- Guchelaar, Henk‐Jan;
- Mathijssen, Ron H. J.;
- Swen, Jesse J.;
- Meulendijks, Didier
Publication type:
Article
Pharmacogenetic‐Pharmacokinetic Interactions in Drug Marketing Authorization Applications via the European Medicines Agency Between 2014 and 2017.
Published in:
Clinical Pharmacology & Therapeutics, 2020, v. 108, n. 2, p. 338, doi. 10.1002/cpt.1834
By:
- Maliepaard, Marc;
- Toiviainen, Timi;
- De Bruin, Marie L.;
- Meulendijks, Didier
Publication type:
Article
Baclofen overdose treated with continuous venovenous hemofiltration.
Published in:
European Journal of Clinical Pharmacology, 2015, v. 71, n. 3, p. 357, doi. 10.1007/s00228-014-1802-y
By:
- Meulendijks, Didier;
- Khan, Saheed;
- Koks, Cornelis;
- Huitema, Alwin;
- Schellens, Jan;
- Beijnen, Jos
Publication type:
Article
Patients homozygous for DPYD c.1129-5923C>G/haplotype B3 have partial DPD deficiency and require a dose reduction when treated with fluoropyrimidines.
Published in:
2016
By:
- Meulendijks, Didier;
- Henricks, Linda;
- Kuilenburg, André;
- Jacobs, Bart;
- Aliev, Abidin;
- Rozeman, Lisette;
- Meijer, Judith;
- Beijnen, Jos;
- Graaf, Hiltje;
- Cats, Annemieke;
- Schellens, Jan;
- Henricks, Linda M;
- van Kuilenburg, André B P;
- Jacobs, Bart A W;
- Beijnen, Jos H;
- de Graaf, Hiltje;
- Schellens, Jan H M
Publication type:
journal article
Phase 1a/1b and pharmacogenetic study of docetaxel, oxaliplatin and capecitabine in patients with advanced cancer of the stomach or the gastroesophageal junction.
Published in:
2015
By:
- Deenen, Maarten;
- Meulendijks, Didier;
- Boot, Henk;
- Legdeur, Marie-Cecile;
- Beijnen, Jos;
- Schellens, Jan;
- Cats, Annemieke;
- Deenen, Maarten J;
- Legdeur, Marie-Cecile J C;
- Beijnen, Jos H;
- Schellens, Jan H M
Publication type:
journal article
Pharmacokinetics of Capecitabine and Four Metabolites in a Heterogeneous Population of Cancer Patients: A Comprehensive Analysis.
Published in:
CPT: Pharmacometrics & Systems Pharmacology, 2019, v. 8, n. 12, p. 940, doi. 10.1002/psp4.12474
By:
- Jacobs, Bart A.W.;
- Deenen, Maarten J.;
- Joerger, Markus;
- Rosing, Hilde;
- Vries, Niels;
- Meulendijks, Didier;
- Cats, Annemieke;
- Beijnen, Jos H.;
- Schellens, Jan H.M.;
- Huitema, Alwin D.R.
Publication type:
Article
Effectiveness and safety of reduced‐dose fluoropyrimidine therapy in patients carrying the DPYD*2A variant: A matched pair analysis.
Published in:
International Journal of Cancer, 2019, v. 144, n. 9, p. 2347, doi. 10.1002/ijc.32022
By:
- Henricks, Linda M.;
- Merendonk, Lisanne N.;
- Meulendijks, Didier;
- Deenen, Maarten J.;
- Beijnen, Jos H.;
- Boer, Anthonius;
- Cats, Annemieke;
- Schellens, Jan H.M.
Publication type:
Article
Rs895819 in MIR27A improves the predictive value of DPYD variants to identify patients at risk of severe fluoropyrimidine-associated toxicity.
Published in:
International Journal of Cancer, 2016, v. 138, n. 11, p. 2752, doi. 10.1002/ijc.30014
By:
- Meulendijks, Didier;
- Henricks, Linda M.;
- Amstutz, Ursula;
- Froehlich, Tanja K.;
- Largiadèr, Carlo R.;
- Beijnen, Jos H.;
- de Boer, Anthonius;
- Deenen, Maarten J.;
- Cats, Annemieke;
- Schellens, Jan H.M.
Publication type:
Article
Increased risk of severe fluoropyrimidine-associated toxicity in patients carrying a G to C substitution in the first 28-bp tandem repeat of the thymidylate synthase 2 R allele.
Published in:
International Journal of Cancer, 2016, v. 138, n. 1, p. 245, doi. 10.1002/ijc.29694
By:
- Meulendijks, Didier;
- Jacobs, Bart A.W.;
- Aliev, Abidin;
- Pluim, Dick;
- van Werkhoven, Erik;
- Deenen, Maarten J.;
- Beijnen, Jos H.;
- Cats, Annemieke;
- Schellens, Jan H.M.
Publication type:
Article
Dihydropyrimidine dehydrogenase gene variants for predicting grade 4-5 fluoropyrimidine-induced toxicity: FUSAFE individual patient data meta-analysis.
Published in:
British Journal of Cancer, 2024, v. 130, n. 5, p. 808, doi. 10.1038/s41416-023-02517-2
By:
- Le Teuff, Gwénaël;
- Cozic, Nathalie;
- Boyer, Jean-Christophe;
- Boige, Valérie;
- Diasio, Robert B.;
- Taieb, Julien;
- Meulendijks, Didier;
- Palles, Claire;
- Schwab, Matthias;
- Deenen, Maarten;
- Largiadèr, Carlo R.;
- Marinaki, Anthony;
- Jennings, Barbara A.;
- Wettergren, Yvonne;
- Di Paolo, Antonello;
- Gross, Eva;
- Budai, Barna;
- Ackland, Stephen P.;
- van Kuilenburg, André B. P.;
- McLeod, Howard L.
Publication type:
Article
Clinical outcome in patients treated with simultaneous integrated boost – intensity modulated radiation therapy (SIB-IMRT) with and without concurrent chemotherapy for squamous cell carcinoma of the anal canal.
Published in:
Acta Oncologica, 2016, v. 55, n. 6, p. 760, doi. 10.3109/0284186X.2015.1124141
By:
- Tomasoa, Nathalie B.;
- Meulendijks, Didier;
- Nijkamp, Jasper;
- Cats, Annemieke;
- Dewit, Luc
Publication type:
Article
Bevacizumab combined with docetaxel, oxaliplatin, and capecitabine, followed by maintenance with capecitabine and bevacizumab, as first-line treatment of patients with advanced HER2-negative gastric cancer: A multicenter phase 2 study.
Published in:
2016
By:
- Meulendijks, Didier;
- de Groot, Jan Willem B.;
- Los, Maartje;
- Boers, James E.;
- Beerepoot, Laurens V.;
- Polee, Marco B.;
- Beeker, Aart;
- Portielje, Johanna E.A.;
- Goey, Swan H.;
- de Jong, Robert S.;
- Vanhoutvin, Steven A.L.W.;
- Kuiper, Maria;
- Sikorska, Karolina;
- Pluim, Dick;
- Beijnen, Jos H.;
- Schellens, Jan H.M.;
- Grootscholten, Cecile;
- Tesselaar, Margot E.T.;
- Cats, Annemieke
Publication type:
journal article

Found: 21