Works by Mettananda, Sachith

Results: 44

Understanding α-globin gene regulation and implications for the treatment of β-thalassemia.

Published in:

Annals of the New York Academy of Sciences, 2016, v. 1368, n. 1, p. 16, doi. 10.1111/nyas.12988

By:

Mettananda, Sachith;
Gibbons, Richard J.;
Higgs, Douglas R.

Publication type:

Article

Recent developments in the treatment of transfusion dependent thalassaemia.

Published in:

2020

By:

Mettananda, S.;
Mettananda, Sachith M

Publication type:

journal article

24 h Activity Guidelines in Children and Adolescents: A Prevalence Survey in Asia-Pacific Cities.

Published in:

International Journal of Environmental Research & Public Health, 2023, v. 20, n. 14, p. 6403, doi. 10.3390/ijerph20146403

By:

Quah, Phaik Ling;
Loo, Benny Kai Guo;
Mettananda, Sachith;
Dassanayake, Senuri;
Chia, Michael Yong Hwa;
Chua, Terence Buan Kiong;
Tan, Teresa Shu Zhen;
Chan, Poh Chong;
But, Betty Wai-Man;
Fu, Antony Chun-Cheung;
Wong, Shirley Man-Yee;
Nagano, Nobuhiko;
Morioka, Ichiro;
Kumar, Shyamal;
Nair, Muttathu K. C.;
Tan, Kok Hian

Publication type:

Article

Constipation During and After the Civil War in Sri Lanka: a Paediatric Study.

Published in:

Journal of Tropical Pediatrics, 2011, v. 57, n. 6, p. 439, doi. 10.1093/tropej/fmr013

By:

Rajindrajith, Shaman;
Mettananda, Sachith;
Devanarayana, Niranga Manjuri

Publication type:

Article

Psychological morbidity among children with transfusion dependent β-thalassaemia and their parents in Sri Lanka.

Published in:

PLoS ONE, 2020, v. 15, n. 2, p. 1, doi. 10.1371/journal.pone.0228733

By:

Mettananda, Sachith;
Peiris, Ravindu;
Pathiraja, Hashan;
Chandradasa, Miyuru;
Bandara, Dayananda;
de Silva, Udaya;
Mettananda, Chamila;
Premawardhena, Anuja

Publication type:

Article

Blood transfusion therapy for β-thalassemia major and hemoglobin E β-thalassemia: Adequacy, trends, and determinants in Sri Lanka.

Published in:

2019

By:

Mettananda, Sachith;
Pathiraja, Hashan;
Peiris, Ravindu;
Wickramarathne, Nethmi;
Bandara, Dayananda;
Silva, Udaya;
Mettananda, Chamila;
Premawardhena, Anuja;
de Silva, Udaya

Publication type:

journal article

Chiari malformation type 1 presenting as unilateral progressive foot drop: a case report and review of literature.

Published in:

2018

By:

Jayamanne, Chamara;
Fernando, Lakkumar;
Mettananda, Sachith

Publication type:

journal article

Neonatal mortality in Sri Lanka: Timing, causes and distribution.

Published in:

Journal of Maternal-Fetal & Neonatal Medicine, 2009, v. 22, n. 9, p. 791, doi. 10.3109/14767050902994549

By:

Rajindrajith, Shaman;
Mettananda, Sachith;
Adihetti, Deshan;
Goonawardana, Ruwan;
Devanarayana, Niranga Manjuri

Publication type:

Article

Marriage patterns in Sri Lanka and the prevalence of parental consanguinity in patients with β-thalassaemia: a cross-sectional descriptive analysis.

Published in:

2020

By:

Premawardhena, Anuja P.;
De Silva, Shamila T.;
Goonatilleke, M. D. Dilith C.;
Ediriweera, Dileepa S.;
Mettananda, Sachith;
Rodrigo, B. K. Rexan P.;
Allen, Angela;
Weatherall, David J.

Publication type:

journal article

Methotrexate-induced leukoencephalopathy presenting as acute-onset limb weakness in a child: a case report.

Published in:

2024

By:

Pathiraja, Hashan;
de Abrew, Gayathri;
de Silva, Linushika;
Fernando, Sanjaya;
Randeny, Shobhavi;
Mettananda, Sachith

Publication type:

Case Study

Place for elective cholecystectomy for patients with severe thalassaemia: a retrospective case control study.

Published in:

2019

By:

Premawardhena, Anuja;
Fernando, Roshanthi;
Kumarage, Sumudu;
Nishad, Nilanga;
Goonatilleke, Dilith;
Silva, Ishari;
Mettananda, Sachith

Publication type:

Case Study

Body iron status of children and adolescents with transfusion dependent β‑thalassaemia: trends of serum ferritin and associations of optimal body iron control.

Published in:

BMC Research Notes, 2018, v. 11, n. 1, p. 1, doi. 10.1186/s13104-018-3634-9

By:

Suriapperuma, Tharindi;
Peiris, Ravindu;
Mettananda, Chamila;
Premawardhena, Anuja;
Mettananda, Sachith

Publication type:

Article

Human induced pluripotent stem cell derived erythroblasts can undergo definitive erythropoiesis and co-express gamma and beta globins.

Published in:

British Journal of Haematology, 2014, v. 166, n. 3, p. 435, doi. 10.1111/bjh.12910

By:

Yang, Cheng‐Tao;
French, Anna;
Goh, Pollyanna Agnes;
Pagnamenta, Alistair;
Mettananda, Sachith;
Taylor, Jenny;
Knight, Sam;
Nathwani, Amit;
Roberts, David J.;
Watt, Suzanne M.;
Carpenter, Lee

Publication type:

Article

A child with Gradenigo syndrome presenting with meningism: a case report.

Published in:

2019

By:

Athapathu, A. S.;
Bandara, E. R. S.;
Aruppala, A. A. H. S.;
Chandrapala, K. M. A. U.;
Mettananda, Sachith

Publication type:

journal article

Knowledge and practices on childhood anaemia, thalassaemia and iron deficiency among mothers of children aged between 6 and 59 months in a suburban area of Sri Lanka.

Published in:

Journal of Health, Population & Nutrition, 2022, v. 41, n. 1, p. 1, doi. 10.1186/s41043-022-00341-7

By:

Samararathna, Ruwan;
Gunaratne, A. V. C.;
Mettananda, Sachith

Publication type:

Article

Direct correction of haemoglobin E β-thalassaemia using base editors.

Published in:

Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-37604-8

By:

Badat, Mohsin;
Ejaz, Ayesha;
Hua, Peng;
Rice, Siobhan;
Zhang, Weijiao;
Hentges, Lance D.;
Fisher, Christopher A.;
Denny, Nicholas;
Schwessinger, Ron;
Yasara, Nirmani;
Roy, Noemi B. A.;
Issa, Fadi;
Roy, Andi;
Telfer, Paul;
Hughes, Jim;
Mettananda, Sachith;
Higgs, Douglas R.;
Davies, James O. J.

Publication type:

Article

Health related quality of life among children with transfusion dependent β-thalassaemia major and haemoglobin E β-thalassaemia in Sri Lanka: a case control study.

Published in:

2019

By:

Mettananda, Sachith;
Pathiraja, Hashan;
Peiris, Ravindu;
Bandara, Dayananda;
de Silva, Udaya;
Mettananda, Chamila;
Premawardhena, Anuja

Publication type:

journal article

Pregnancy and neonatal outcomes of assisted pregnancies in a low-middle income country in South Asia.

Published in:

BMC Pregnancy & Childbirth, 2025, v. 25, n. 1, p. 1, doi. 10.1186/s12884-025-07631-y

By:

Mettananda, Sachith;
Herath, Himali;
Madushith, Ranod;
Dias, Tiran;
Herath, Rasika;
Goonewardena, Sampatha;
Rowel, Dhammica;
Daniel, Abner Elkan;
Perera, Susie

Publication type:

Article

Synergistic silencing of α-globin and induction of γ-globin by histone deacetylase inhibitor, vorinostat as a potential therapy for β-thalassaemia.

Published in:

Scientific Reports, 2019, v. 9, n. 1, p. N.PAG, doi. 10.1038/s41598-019-48204-2

By:

Mettananda, Sachith;
Yasara, Nirmani;
Fisher, Christopher A.;
Taylor, Stephen;
Gibbons, Richard;
Higgs, Doug

Publication type:

Article

Spondylocostal Dysplasia in a 7-Year-Old Sri Lankan Girl Causing Restrictive Lung Disease: A Case Report and Review of the Literature.

Published in:

Case Reports in Medicine, 2020, p. 1, doi. 10.1155/2020/9241207

By:

Kamalanathan, Phirarthana;
Fernando, Meranthi;
Jayawardena, Rohan;
Upasena, A.;
Rajindrajith, Shaman;
Mettananda, Sachith

Publication type:

Article

Spondylocostal Dysplasia in a 7-Year-Old Sri Lankan Girl Causing Restrictive Lung Disease: A Case Report and Review of the Literature.

Published in:

Case Reports in Medicine, 2020, p. 1, doi. 10.1155/2020/9241207

By:

Kamalanathan, Phirarthana;
Fernando, Meranthi;
Jayawardena, Rohan;
Upasena, A.;
Rajindrajith, Shaman;
Mettananda, Sachith

Publication type:

Article

A large pericardial cystic lymphangioma presenting as acute-onset respiratory distress in a child: a case report.

Published in:

2022

By:

Pathiraja, Hashan;
Rasnayake, Dhammike;
Muthukumarana, Thilini;
de Silva, Channa;
Sathkorala, Wasantha;
Gunaratne, Sandini;
Rajindrajith, Shaman;
Mettananda, Sachith

Publication type:

Case Study

Kagami-Ogata syndrome: a case report.

Published in:

2022

By:

Suriapperuma, Tharindi;
Randeny, Shobhavi;
Mettananda, Sachith

Publication type:

Case Study

Composition, determinants, and risk factors of low birth weight in Sri Lanka.

Published in:

PLoS ONE, 2025, v. 20, n. 2, p. 1, doi. 10.1371/journal.pone.0318554

By:

Mettananda, Sachith;
Herath, Himali;
Thewage, Ayesha;
Nanayakkara, Kumudu;
Liyanage, Indeewari;
Udani, K. S.;
Savanadasa, Rajika;
Goonewardena, Sampatha;
Gamhewage, Nimesha;
Hewamalage, Asiri;
Rowel, Dhammica;
Daniel, Abner Elkan;
de Silva, Chithramalee;
Perera, Susie

Publication type:

Article

Tender cervical lymphadenitis as a herald of multi-system inflammatory syndrome in COVID-19 infection of children and adolescents: a report of two cases.

Published in:

2022

By:

Wanninayake, Leonard;
de Abrew, Gayathree;
Logeshwaran, Dinusha;
Weerasinghe, Chathurika;
Gowinna, Piyumi;
Mettananda, Sachith;
Premaratna, Ranjan

Publication type:

Case Study

Editing an α-globin enhancer in primary human hematopoietic stem cells as a treatment for β-thalassemia.

Published in:

Nature Communications, 2017, v. 8, n. 1, p. 1, doi. 10.1038/s41467-017-00479-7

By:

Mettananda, Sachith;
Fisher, Chris A.;
Hay, Deborah;
Badat, Mohsin;
Quek, Lynn;
Clark, Kevin;
Hublitz, Philip;
Downes, Damien;
Kerry, Jon;
Gosden, Matthew;
Telenius, Jelena;
Sloane-Stanley, Jackie A.;
Faustino, Paula;
Coelho, Andreia;
Doondeea, Jessica;
Usukhbayar, Batchimeg;
Sopp, Paul;
Sharpe, Jacqueline A.;
Hughes, Jim R.;
Vyas, Paresh

Publication type:

Article

Smith-Lemli-Opitz syndrome presenting as acute adrenal crisis in a child: a case report.

Published in:

2018

By:

Jayamanne, Chamara;
Sandamal, Sajith;
Jayasundara, Kasun;
Saranavabavananthan, Mayoorathy;
Mettananda, Sachith

Publication type:

journal article

Streptococcus bovis - unusual etiology of meningitis in a neonate with Down syndrome: a case report.

Published in:

2018

By:

Mettananda, Sachith;
Kamalanathan, Phirarthana;
Dhananja Namalie, K.

Publication type:

journal article

Anaemia among females in child-bearing age: Relative contributions, effects and interactions of α- and β-thalassaemia.

Published in:

PLoS ONE, 2018, v. 13, n. 11, p. 1, doi. 10.1371/journal.pone.0206928

By:

Mettananda, Sachith;
Suranjan, Marius;
Fernando, Roshale;
Dias, Tiran;
Mettananda, Chamila;
Rodrigo, Rexan;
Perera, Lakshman;
Gibbons, Richard;
Premawardhena, Anuja;
Higgs, Douglas

Publication type:

Article

Vitamin B12 responsive developmental and epileptic encephalopathy due to a novel mutation in the FUT2 gene: a case report.

Published in:

BMC Pediatrics, 2024, v. 24, n. 1, p. 1, doi. 10.1186/s12887-024-05106-1

By:

Bandara, PKBUC;
Wijenayake, Wasana;
Fernando, Sanjaya;
Padeniya, Padmapani;
Mettananda, Sachith

Publication type:

Article

Familial glucocorticoid deficiency presenting with hyperpigmentation, gigantism, and motor development delay: a case report.

Published in:

2019

By:

Uyangoda, Kanchana;
Kamalanathan, Phirarthana;
Mettananda, Sachith

Publication type:

journal article

Leg Ulcers: A Report in Patients with Hemoglobin E Beta Thalassemia and Review of the Literature in Severe Beta Thalassemia.

Published in:

Acta Haematologica, 2022, v. 145, n. 3, p. 334, doi. 10.1159/000520731

By:

Mehta, Vikita;
Kirubarajan, Abirami;
Sabouhanian, Amir;
Jayawardena, Sanasi M.;
Chandrakumaran, Priya;
Thangavelu, Nila;
Cader, Refai;
Mettananda, Sachith;
Bandara, Dayananda;
Khan, Shawn;
Weatherall, David J.;
Allen, Angela;
Premawardhena, Anuja P.;
Olivieri, Nancy F.

Publication type:

Article

Electronic screen device usage and screen time among preschool-attending children in a suburban area of Sri Lanka.

Published in:

2022

By:

Rathnasiri, Asanka;
Rathnayaka, Harsha;
Yasara, Nirmani;
Mettananda, Sachith

Publication type:

journal article

Analysis of Effects of Meteorological Factors on Dengue Incidence in Sri Lanka Using Time Series Data

Published in:

PLoS ONE, 2013, v. 8, n. 5, p. 1, doi. 10.1371/journal.pone.0063717

By:

Goto, Kensuke;
Kumarendran, Balachandran;
Mettananda, Sachith;
Gunasekara, Deepa;
Fujii, Yoshito;
Kaneko, Satoshi

Publication type:

Article

Lysinuric protein intolerance presenting as pancytopenia and splenomegaly mimicking acute leukaemia: a case report.

Published in:

2023

By:

Lokuhewage, Chanika;
Pathiraja, Hashan;
Madawala, Piyumi;
Bandara, Sudarshana;
Mettananda, Sachith

Publication type:

Case Study

A randomised double-blind placebo-controlled clinical trial of oral hydroxyurea for transfusion-dependent β-thalassaemia.

Published in:

Scientific Reports, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41598-022-06774-8

By:

Yasara, Nirmani;
Wickramarathne, Nethmi;
Mettananda, Chamila;
Silva, Ishari;
Hameed, Nizri;
Attanayaka, Kumari;
Rodrigo, Rexan;
Wickramasinghe, Nirmani;
Perera, Lakshman;
Manamperi, Aresha;
Premawardhena, Anuja;
Mettananda, Sachith

Publication type:

Article

Microcytic anemia in children: parallel screening for iron deficiency and thalassemia provides a useful opportunity for thalassemia prevention in low- and middle-income countries.

Published in:

Pediatric Hematology & Oncology, 2020, v. 37, n. 4, p. 326, doi. 10.1080/08880018.2020.1725200

By:

Mettananda, Sachith;
Paranamana, Sanjaya;
Fernando, Roshale;
Suranjan, Marius;
Rodrigo, Rexan;
Perera, Lakshman;
Vipulaguna, Thakshila;
Fernando, Prasanna;
Fernando, Mallika;
Dayanath, B. K. T. P.;
Costa, Yasintha;
Premawardhena, Anuja

Publication type:

Article

Posterior reversible encephalopathy syndrome in a survivor of valproate-induced acute liver failure: a case report.

Published in:

2013

By:

Mettananda, Sachith;
Fernando, Asvini D.;
Ginige, Nimasari

Publication type:

journal article

A child with Imerslund-Gräsbeck syndrome concealed by co-existing α-thalassaemia presenting with subacute combined degeneration of the spinal cord: a case report.

Published in:

2021

By:

Arunath, Visvalingam;
Hoole, Thabitha Jebaseeli;
Rathnasri, Asanka;
Muthukumarana, Oshanie;
Kumarasiri, Ishara Minuri;
Liyanage, Nishadi Dananjani;
Costa, Yasintha;
Mettananda, Sachith

Publication type:

journal article

A rare co-occurrence of duchenne muscular dystrophy, congenital adrenal hypoplasia and glycerol kinase deficiency due to Xp21 contiguous gene deletion syndrome: case report.

Published in:

BMC Endocrine Disorders, 2021, v. 21, n. 1, p. 1, doi. 10.1186/s12902-021-00876-6

By:

Rathnasiri, Asanka;
Senarathne, Udara;
Arunath, Visvalingam;
Hoole, Thabitha;
Kumarasiri, Ishara;
Muthukumarana, Oshanie;
Jasinge, Eresha;
Mettananda, Sachith

Publication type:

Article

Association of GDF15 levels with body mass index and endocrine status in β‐thalassaemia.

Published in:

Clinical Endocrinology, 2023, v. 99, n. 2, p. 182, doi. 10.1111/cen.14897

By:

Karusheva, Yanislava;
Petry, Clive J.;
Yasara, Nirmani;
Kottahachchi, Dulani;
Premawardhena, Anuja;
Barker, Peter;
Burling, Keith;
Sattar, Naveed;
Welsh, Paul;
Mettananda, Sachith;
O'Rahilly, Stephen

Publication type:

Article

Acute Disseminated Encephalomyelitis Presenting as Bilateral Ptosis in a Sri Lankan Child.

Published in:

2022

By:

Kumarasiri, Ishara;
Samararathna, Ruwan;
Sandakelum, Udara;
Muthukumarana, Oshanie;
Balasubramaniam, Reha;
Mettananda, Sachith

Publication type:

Case Study

Severe Disfiguring Scalp and Facial Oedema due to Henoch–Schönlein Purpura in a Child.

Published in:

Case Reports in Pediatrics, 2020, p. 1, doi. 10.1155/2020/8823611

By:

Arunath, Visvalingam;
Athapathu, Arjuna Salinda;
Hoole, Thabitha Jebaseeli;
Aruppala, Heshan;
Rathnasri, Asanka;
Ranawaka, Randula;
Mettananda, Sachith

Publication type:

Article

A comprehensive review of hydroxyurea for β-haemoglobinopathies: the role revisited during COVID-19 pandemic.

Published in:

2021

By:

Yasara, Nirmani;
Premawardhena, Anuja;
Mettananda, Sachith

Publication type:

journal article