Works by Methner, Axel

Results: 40

Regulation of xCT expression and system function in neuronal cells.

Published in:

Amino Acids, 2012, v. 42, n. 1, p. 171, doi. 10.1007/s00726-011-0862-x

By:

Lewerenz, Jan;
Maher, Pamela;
Methner, Axel

Publication type:

Article

Curcumin therapy in a Plp1 transgenic mouse model of Pelizaeus-Merzbacher disease.

Published in:

Annals of Clinical & Translational Neurology, 2015, v. 2, n. 8, p. 787, doi. 10.1002/acn3.219

By:

Epplen, Dirk B.;
Prukop, Thomas;
Nientiedt, Tobias;
Albrecht, Philipp;
Arlt, Friederike A.;
Stassart, Ruth M.;
Kassmann, Celia M.;
Methner, Axel;
Nave, Klaus‐Armin;
Werner, Hauke B.;
Sereda, Michael W.

Publication type:

Article

Expression of genes encoding the calcium signalosome in cellular and transgenic models of Huntington's disease.

Published in:

Frontiers in Molecular Neuroscience, 2013, v. 6, p. 1, doi. 10.3389/fnmol.2013.00042

By:

Czeredys, Magdalena;
Gruszczynska-Biegala, Joanna;
Schacht, Teresa;
Methner, Axel;
Kuznicki, Jacek

Publication type:

Article

Redox Modifications of Proteins of the Mitochondrial Fusion and Fission Machinery.

Published in:

Cells (2073-4409), 2020, v. 9, n. 4, p. 815, doi. 10.3390/cells9040815

By:

Wolf, Christina;
López del Amo, Víctor;
Arndt, Sabine;
Bueno, Diones;
Tenzer, Stefan;
Hanschmann, Eva-Maria;
Berndt, Carsten;
Methner, Axel

Publication type:

Article

The Charcot–Marie Tooth Disease Mutation R94Q in MFN2 Decreases ATP Production but Increases Mitochondrial Respiration under Conditions of Mild Oxidative Stress.

Published in:

Cells (2073-4409), 2019, v. 8, n. 10, p. 1289, doi. 10.3390/cells8101289

By:

Wolf, Christina;
Zimmermann, Rahel;
Thaher, Osamah;
Bueno, Diones;
Wüllner, Verena;
Schäfer, Michael K.E.;
Albrecht, Philipp;
Methner, Axel

Publication type:

Article

Genetic shift of env V3 loop viral sequences in patients with HIV-associated neurocognitive disorder during antiretroviral therapy.

Published in:

Journal of NeuroVirology, 2013, v. 19, n. 6, p. 523, doi. 10.1007/s13365-013-0207-5

By:

Eggers, Christian;
Müller, Oliver;
Thordsen, Ingo;
Schreiber, Michael;
Methner, Axel

Publication type:

Article

Bax Inhibitor-1 Is Likely a pH-Sensitive Calcium Leak Channel, Not a H+/Ca2+ Exchanger.

Published in:

Science Signaling, 2014, v. 7, n. 343, p. 1, doi. 10.1126/scisignal.2005764

By:

Bultynck, Geert;
Kiviluoto, Santeri;
Methner, Axel

Publication type:

Article

Promoting Myelination in an In Vitro Mouse Model of the Peripheral Nerve System: The Effect of Wine Ingredients.

Published in:

PLoS ONE, 2013, v. 8, n. 6, p. 1, doi. 10.1371/journal.pone.0066079

By:

Stettner, Mark;
Wolffram, Kathleen;
Mausberg, Anne K.;
Albrecht, Philipp;
Derksen, Angelika;
Methner, Axel;
Dehmel, Thomas;
Hartung, Hans-Peter;
Dietrich, Helmut;
Kieseier, Bernd C.

Publication type:

Article

Retinal Neurodegeneration in Wilson's Disease Revealed by Spectral Domain Optical Coherence Tomography.

Published in:

PLoS ONE, 2012, v. 7, n. 11, p. 1, doi. 10.1371/journal.pone.0049825

By:

Albrecht, Philipp;
Müller, Ann-Kristin;
Ringelstein, Marius;
Finis, David;
Geerling, Gerd;
Cohn, Eva;
Aktas, Orhan;
Hartung, Hans-Peter;
Hefter, Harald;
Methner, Axel

Publication type:

Article

Optical Coherence Tomography in Parkinsonian Syndromes.

Published in:

PLoS ONE, 2012, v. 7, n. 4, p. 1, doi. 10.1371/journal.pone.0034891

By:

Albrecht, Philipp;
Müller, Ann-Kristin;
Südmeyer, Martin;
Ferrea, Stefano;
Ringelstein, Marius;
Cohn, Eva;
Aktas, Orhan;
Dietlein, Thomas;
Lappas, Alexandra;
Foerster, Andreas;
Hartung, Hans- Peter;
Schnitzler, Alfons;
Methner, Axel

Publication type:

Article

Role of the G-Protein-Coupled Receptor GPR12 as High-Affiity Receptor for Sphingosylphosphorylcholine and Its Expression and Function in Brain Development.

Published in:

Journal of Neuroscience, 2003, v. 23, n. 3, p. 907, doi. 10.1523/JNEUROSCI.23-03-00907.2003

By:

Ignatov, Atanas;
Lintzel, Julia;
Hermans-Borgmeyer, Irm;
Kreienkamp, Hans-Jurgen;
Joost, Patrick;
thomsen, Susanne;
Methner, axel;
Schaller, H. Chica

Publication type:

Article

Mitochondrial function and energy metabolism in neuronal HT22 cells resistant to oxidative stress.

Published in:

British Journal of Pharmacology, 2014, v. 171, n. 8, p. 2147, doi. 10.1111/bph.12549

By:

Pfeiffer, Annika;
Jaeckel, Martin;
Lewerenz, Jan;
Noack, Rebecca;
Pouya, Alireza;
Schacht, Teresa;
Hoffmann, Christina;
Winter, Jennifer;
Schweiger, Susann;
Schäfer, Michael K E;
Methner, Axel

Publication type:

Article

NECAB family of neuronal calcium-binding proteins in health and disease.

Published in:

Neural Regeneration Research, 2025, v. 20, n. 5, p. 1236, doi. 10.4103/NRR.NRR-D-24-00094

By:

Bueno, Diones;
Schäfer, Michael K. E.;
Wang, Sudena;
Schmeisser, Michael J.;
Methner, Axel

Publication type:

Article

The immunosuppressive mechanism of dimethyl fumarate involves altered intracellular Ca2+ handling.

Published in:

Journal of Cellular Neuroscience & Oxidative Stress, 2018, v. 10, n. 2, p. 687

By:

HERRMANN, Ann-Kathrin;
WUNDER, Felix;
WÜLLNER, Verena;
Jialin CHEN;
VANGHELUWE, Peter;
SEITAJ, Bruno;
BULTYNCK, Geert;
ALLEN, Yen;
BOLOTINA, Victoria;
HAMILTON, Nicola;
METHNER, Axel

Publication type:

Article

Dimethyl Fumarate Induces Glutathione Recycling by Upregulation of Glutathione Reductase.

Published in:

Oxidative Medicine & Cellular Longevity, 2017, p. 1, doi. 10.1155/2017/6093903

By:

Hoffmann, Christina;
Dietrich, Michael;
Herrmann, Ann-Kathrin;
Schacht, Teresa;
Albrecht, Philipp;
Methner, Axel

Publication type:

Article

Charcot–Marie–Tooth disease CMT4A: GDAP1 increases cellular glutathione and the mitochondrial membrane potential.

Published in:

Human Molecular Genetics, 2012, v. 21, n. 1, p. 150, doi. 10.1093/hmg/ddr450

By:

Noack, Rebecca;
Frede, Svenja;
Albrecht, Philipp;
Henke, Nadine;
Pfeiffer, Annika;
Knoll, Katrin;
Dehmel, Thomas;
Meyer zu Hörste, Gerd;
Stettner, Mark;
Kieseier, Bernd C.;
Summer, Holger;
Golz, Stefan;
Kochanski, Andrzej;
Wiedau-Pazos, Martina;
Arnold, Susanne;
Lewerenz, Jan;
Methner, Axel

Publication type:

Article

The more the merrier? Scoring, statistics and animal welfare in experimental autoimmune encephalomyelitis.

Published in:

Laboratory Animals, 2016, v. 50, n. 6, p. 427, doi. 10.1177/0023677216675008

By:

Palle, Pushpalatha;
Ferreira, Filipa M.;
Methner, Axel;
Buch, Thorsten

Publication type:

Article

Cooperative action of glutamate transporters and cystine/glutamate antiporter system Xc– protects from oxidative glutamate toxicity.

Published in:

Journal of Neurochemistry, 2006, v. 98, n. 3, p. 916, doi. 10.1111/j.1471-4159.2006.03921.x

By:

Lewerenz, Jan;
Klein, Mathias;
Methner, Axel

Publication type:

Article

Activation of stimulatory heterotrimeric G proteins increases glutathione and protects neuronal cells against oxidative stress.

Published in:

Journal of Neurochemistry, 2003, v. 87, n. 2, p. 522, doi. 10.1046/j.1471-4159.2003.02019.x

By:

Lewerenz, Jan;
Letz, Julia;
Methner, Axel

Publication type:

Article

New Probucol Analogues Inhibit Ferroptosis, Improve Mitochondrial Parameters, and Induce Glutathione Peroxidase in HT22 Cells.

Published in:

Molecular Neurobiology, 2020, v. 57, n. 8, p. 3273, doi. 10.1007/s12035-020-01956-9

By:

Bueno, Diones Caeran;
Canto, Rômulo Faria Santos;
de Souza, Viviane;
Andreguetti, Rafaela Rafognatto;
Barbosa, Flávio Augusto Rocha;
Naime, Aline Aita;
Dey, Partha Narayan;
Wüllner, Verena;
Lopes, Mark William;
Braga, Antônio Luiz;
Methner, Axel;
Farina, Marcelo

Publication type:

Article

Presenilin-1 Delta E9 Mutant Induces STIM1-Driven Store-Operated Calcium Channel Hyperactivation in Hippocampal Neurons.

Published in:

Molecular Neurobiology, 2018, v. 55, n. 6, p. 4667, doi. 10.1007/s12035-017-0674-4

By:

Ryazantseva, Maria;
Goncharova, Anna;
Skobeleva, Kseniia;
Erokhin, Maksim;
Methner, Axel;
Georgiev, Pavel;
Kaznacheyeva, Elena

Publication type:

Article

Dimethyl fumarate treatment after traumatic brain injury prevents depletion of antioxidative brain glutathione and confers neuroprotection.

Published in:

Journal of Neurochemistry, 2017, v. 143, n. 5, p. 523, doi. 10.1111/jnc.14220

By:

Krämer, Tobias;
Grob, Theresa;
Menzel, Lutz;
Hirnet, Tobias;
Griemert, Eva;
Radyushkin, Konstantin;
Thal, Serge C.;
Methner, Axel;
Schaefer, Michael K. E.

Publication type:

Article

Induction of Nrf2 and xCT are involved in the action of the neuroprotective antibiotic ceftriaxone in vitro.

Published in:

Journal of Neurochemistry, 2009, v. 111, n. 2, p. 332, doi. 10.1111/j.1471-4159.2009.06347.x

By:

Lewerenz, Jan;
Albrecht, Philipp;
Tien, Mai-Ly Tran;
Henke, Nadine;
Karumbayaram, Saravanan;
Kornblum, Harley I.;
Wiedau-Pazos, Martina;
Schubert, Dave;
Maher, Pamela;
Methner, Axel

Publication type:

Article

An improved method for precise genome editing in zebrafish using CRISPR-Cas9 technique.

Published in:

Molecular Biology Reports, 2021, v. 48, n. 2, p. 1951, doi. 10.1007/s11033-020-06125-8

By:

Gasanov, Eugene V.;
Jędrychowska, Justyna;
Pastor, Michal;
Wiweger, Malgorzata;
Methner, Axel;
Korzh, Vladimir P.

Publication type:

Article

Oxytosis/Ferroptosis-(Re-) Emerging Roles for Oxidative Stress-Dependent Non-apoptotic Cell Death in Diseases of the Central Nervous System.

Published in:

Frontiers in Neuroscience, 2018, p. 1, doi. 10.3389/fnins.2018.00214

By:

Lewerenz, Jan;
Ates, Gamze;
Methner, Axel;
Conrad, Marcus;
Maher, Pamela

Publication type:

Article

Mechanismen und Bedeutung der oxidativen Glutamattoxizität.

Published in:

Neuroforum, 2006, v. 12, n. 3, p. 222, doi. 10.1515/nf-2006-0303

By:

Lewerenz, Jan;
Methner, Axel

Publication type:

Article

Effects of dimethyl fumarate on neuroprotection and immunomodulation.

Published in:

Journal of Neuroinflammation, 2012, v. 9, n. 1, p. 163, doi. 10.1186/1742-2094-9-163

By:

Albrecht, Philipp;
Bouchachia, Imane;
Goebels, Norbert;
Henke, Nadine;
Hofstetter, Harald H.;
Issberner, Andrea;
Kovacs, Zsuzsa;
Lewerenz, Jan;
Lisak, Dmitrij;
Maher, Pamela;
Mausberg, Anne-Kathrin;
Quasthoff, Kim;
Zimmermann, Corinna;
Hartung, Hans-Peter;
Methner, Axel

Publication type:

Article

Induction of Bcl-2 by functional regulation of G-protein coupled receptors protects from oxidative glutamate toxicity by increasing glutathione

Published in:

Free Radical Research, 2006, v. 40, n. 11, p. 1113, doi. 10.1080/10715760600838191

By:

Sahin, Mert;
Saxena, Ambrish;
Joost, Patrick;
Lewerenz, Jan;
Methner, Axel

Publication type:

Article

Transmembrane BAX Inhibitor-1 Motif Containing Protein 5 (TMBIM5) Sustains Mitochondrial Structure, Shape, and Function by Impacting the Mitochondrial Protein Synthesis Machinery.

Published in:

Cells (2073-4409), 2020, v. 9, n. 10, p. 2147, doi. 10.3390/cells9102147

By:

Seitaj, Bruno;
Maull, Felicia;
Zhang, Li;
Wüllner, Verena;
Wolf, Christina;
Schippers, Philipp;
La Rovere, Rita;
Distler, Ute;
Tenzer, Stefan;
Parys, Jan B.;
Bultynck, Geert;
Methner, Axel

Publication type:

Article

Protein kinase inhibitor ß enhances the constitutive activity of G-protein-coupled zinc receptor GPR39.

Published in:

Biochemical Journal, 2014, v. 462, n. 1, p. 125, doi. 10.1042/BJ20131198

By:

KOVACS, Zsuzsa;
SCHACHT, Teresa;
HERRMANN, Ann-Kathrin;
ALBRECHT, Philipp;
LEFKIMMIATIS, Konstantinos;
METHNER, Axel

Publication type:

Article

Iron-sulfur cluster loss in mitochondrial CISD1 mediates PINK1 loss-of-function phenotypes.

Published in:

eLife, 2024, p. 1, doi. 10.7554/eLife.97027

By:

Bitar, Sara;
Baumann, Timo;
Weber, Christopher;
Abusaada, Majd;
Rojas-Charry, Liliana;
Ziegler, Patrick;
Schettgen, Thomas;
Randerath, Isabella Eva;
Venkataramani, Vivek;
Michalke, Bernhard;
Hanschmann, Eva-Maria;
Arena, Giuseppe;
Krueger, Rejko;
Li Zhang;
Methner, Axel

Publication type:

Article

Absence of system xc- on immune cells invading the central nervous system alleviates experimental autoimmune encephalitis.

Published in:

2017

By:

Merckx, Ellen;
Albertini, Giulia;
Paterka, Magdalena;
Jensen, Cathy;
Albrecht, Philipp;
Dietrich, Michael;
Van Liefferinge, Joeri;
Bentea, Eduard;
Verbruggen, Lise;
Demuyser, Thomas;
Deneyer, Lauren;
Lewerenz, Jan;
van Loo, Geert;
De Keyser, Jacques;
Sato, Hideyo;
Maher, Pamela;
Methner, Axel;
Massie, Ann

Publication type:

journal article

Optical coherence tomography for the diagnosis and monitoring of idiopathic intracranial hypertension.

Published in:

Journal of Neurology, 2017, v. 264, n. 7, p. 1370, doi. 10.1007/s00415-017-8532-x

By:

Albrecht, Philipp;
Blasberg, Christine;
Ringelstein, Marius;
Müller, Ann-Kristin;
Finis, David;
Guthoff, Rainer;
Kadas, Ella-Maria;
Lagreze, Wolf;
Aktas, Orhan;
Hartung, Hans-Peter;
Paul, Friedemann;
Brandt, Alexander;
Methner, Axel

Publication type:

Article

Guillain-Barré syndrome variant with prominent facial diplegia, limb paresthesia, and brisk reflexes.

Published in:

2012

By:

Lehmann, Helmar;
Macht, Stephan;
Jander, Sebastian;
Hartung, Hans-Peter;
Methner, Axel

Publication type:

Letter

Free caspase activity in CSF of patients with dementia.

Published in:

2009

By:

Albrecht, P.;
Schmitz, M.;
Otto, M.;
Hemmer, B.;
Zerr, I.;
Hartung, H.-P.;
Methner, Axel

Publication type:

Letter

Optical coherence tomography measures axonal loss in multiple sclerosis independently of optic neuritis.

Published in:

Journal of Neurology, 2007, v. 254, n. 11, p. 1595, doi. 10.1007/s00415-007-0538-3

By:

Albrecht, Philipp;
Fröhlich, Ruth;
Hartung, Hans-Peter;
Kieseier, Bernd C.;
Methner, Axel

Publication type:

Article

Chronic social stress disrupts the intracellular redistribution of brain hexokinase 3 induced by shifts in peripheral glucose levels.

Published in:

Journal of Molecular Medicine, 2022, v. 100, n. 10, p. 1441, doi. 10.1007/s00109-022-02235-x

By:

van der Kooij, Michael A.;
Rojas-Charry, Liliana;
Givehchi, Maryam;
Wolf, Christina;
Bueno, Diones;
Arndt, Sabine;
Tenzer, Stefan;
Mattioni, Lorenzo;
Treccani, Giulia;
Hasch, Annika;
Schmeisser, Michael J.;
Vianello, Caterina;
Giacomello, Marta;
Methner, Axel

Publication type:

Article

Abnormalities of synaptic mitochondria in autism spectrum disorder and related neurodevelopmental disorders.

Published in:

Journal of Molecular Medicine, 2021, v. 99, n. 2, p. 161, doi. 10.1007/s00109-020-02018-2

By:

Rojas-Charry, Liliana;
Nardi, Leonardo;
Methner, Axel;
Schmeisser, Michael J.

Publication type:

Article

Bax inhibitor-1 deficiency leads to obesity by increasing Ca2+-dependent insulin secretion.

Published in:

Journal of Molecular Medicine, 2020, v. 98, n. 6, p. 849, doi. 10.1007/s00109-020-01914-x

By:

Philippaert, Koenraad;
Roden, Michael;
Lisak, Dmitrij;
Bueno, Diones;
Jelenik, Tomas;
Radyushkin, Konstantin;
Schacht, Teresa;
Mesuere, Margot;
Wüllner, Verena;
Herrmann, Ann-Kathrin;
Baumgart, Jan;
Vennekens, Rudi;
Methner, Axel

Publication type:

Article

Regulators of mitochondrial Ca homeostasis in cerebral ischemia.

Published in:

Cell & Tissue Research, 2014, v. 357, n. 2, p. 395, doi. 10.1007/s00441-014-1807-y

By:

Schäfer, Michael;
Pfeiffer, Annika;
Jaeckel, Martin;
Pouya, Alireza;
Dolga, Amalia;
Methner, Axel

Publication type:

Article