Works matching AU Messersmith, Wells

Results: 57
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    A Phase I Dose‐Escalation Study of Linsitinib (OSI‐906), a Small‐Molecule Dual Insulin‐Like Growth Factor‐1 Receptor/Insulin Receptor Kinase Inhibitor, in Combination with Irinotecan in Patients with Advanced Cancer.

    Published in:
    Oncologist, 2018, v. 23, n. 12, p. 1409, doi. 10.1634/theoncologist.2018-0315
    By:
    • Davis, S. Lindsey;
    • Eckhardt, S. Gail;
    • Diamond, Jennifer R.;
    • Messersmith, Wells A.;
    • Dasari, Arvind;
    • Weekes, Colin D.;
    • Lieu, Christopher H.;
    • Kane, Madeline;
    • Choon Tan, Aik;
    • Pitts, Todd M.;
    • Leong, Stephen
    Publication type:
    Article
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    Phase II Study of Olaparib (AZD-2281) After Standard Systemic Therapies for Disseminated Colorectal Cancer.

    Published in:
    Oncologist, 2016, v. 21, n. 2, p. 172, doi. 10.1634/theoncologist.2015-0319
    By:
    • Leichman, Lawrence;
    • Groshen, Susan;
    • O'Neil, Bert H.;
    • Messersmith, Wells;
    • Berlin, Jordan;
    • Chan, Emily;
    • Leichman, Cynthia G.;
    • Cohen, Steven J.;
    • Cohen, Deirdre;
    • Lenz, Heinz‐Josef;
    • Gold, Philip;
    • Boman, Bruce;
    • Fielding, Anitra;
    • Locker, Gershon;
    • Cason, Ronald C.;
    • Hamilton, Stan R.;
    • Hochster, Howard S.
    Publication type:
    Article
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    ALDH<sup>+</sup> tumor-initiating cells exhibiting gain in NOTCH1 gene copy number have enhanced regrowth sensitivity to a γ-secretase inhibitor and irinotecan in colorectal cancer

    Published in:
    Molecular Oncology, 2012, v. 6, n. 3, p. 370, doi. 10.1016/j.molonc.2012.03.004
    By:
    • Arcaroli, John J.;
    • Powell, Rebecca W.;
    • Varella-Garcia, Marileila;
    • McManus, Martine;
    • Tan, Aik Choon;
    • Quackenbush, Kevin S.;
    • Pitts, Todd M.;
    • Gao, Dexiang;
    • Spreafico, Anna;
    • Dasari, Arvind;
    • Touban, Basel M.;
    • Messersmith, Wells A.
    Publication type:
    Article
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    Impact of Radiation Dose on Postoperative Complications in Esophageal and Gastroesophageal Junction Cancers.

    Published in:
    Frontiers in Oncology, 2021, v. 11, p. N.PAG, doi. 10.3389/fonc.2021.614640
    By:
    • Kastelowitz, Noah;
    • Marsh, Megan D.;
    • McCarter, Martin;
    • Meguid, Robert A.;
    • Bhardwaj, Narine Wandrey;
    • Mitchell, John D.;
    • Weyant, Michael J.;
    • Scott, Christopher;
    • Schefter, Tracey;
    • Stumpf, Priscilla;
    • Leong, Stephen;
    • Messersmith, Wells;
    • Lieu, Christopher;
    • Leal, Alexis D.;
    • Davis, S. Lindsey;
    • Purcell, William T.;
    • Kane, Madeleine;
    • Wani, Sachin;
    • Shah, Raj;
    • Hammad, Hazem
    Publication type:
    Article
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    A Phase Ib study evaluating MNRP1685A, a fully human anti-NRP1 monoclonal antibody, in combination with bevacizumab and paclitaxel in patients with advanced solid tumors.

    Published in:
    Cancer Chemotherapy & Pharmacology, 2014, v. 73, n. 5, p. 951, doi. 10.1007/s00280-014-2426-8
    By:
    • Patnaik, Amita;
    • LoRusso, Patricia;
    • Messersmith, Wells;
    • Papadopoulos, Kyriakos;
    • Gore, Lia;
    • Beeram, Muralidhar;
    • Ramakrishnan, Vanitha;
    • Kim, Amy;
    • Beyer, Joseph;
    • Mason Shih, L.;
    • Darbonne, Walter;
    • Xin, Yan;
    • Yu, Ron;
    • Xiang, Hong;
    • Brachmann, Rainer;
    • Weekes, Colin
    Publication type:
    Article
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    A phase II study of antibody-drug conjugate, TAK-264 (MLN0264) in previously treated patients with advanced or metastatic pancreatic adenocarcinoma expressing guanylyl cyclase C.

    Published in:
    Investigational New Drugs, 2017, v. 35, n. 5, p. 634, doi. 10.1007/s10637-017-0473-9
    By:
    • Almhanna, Khaldoun;
    • Wright, David;
    • Mercade, Teresa;
    • Van Laethem, Jean-Luc;
    • Gracian, Antonio;
    • Guillen-Ponce, Carmen;
    • Faris, Jason;
    • Lopez, Carolina;
    • Hubner, Richard;
    • Bendell, Johanna;
    • Bols, Alain;
    • Feliu, Jaime;
    • Starling, Naureen;
    • Enzinger, Peter;
    • Mahalingham, Devalingham;
    • Messersmith, Wells;
    • Yang, Huyuan;
    • Fasanmade, Adedigbo;
    • Danaee, Hadi;
    • Kalebic, Thea
    Publication type:
    Article
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    Phase II study of the antibody-drug conjugate TAK-264 (MLN0264) in patients with metastatic or recurrent adenocarcinoma of the stomach or gastroesophageal junction expressing guanylyl cyclase C.

    Published in:
    Investigational New Drugs, 2017, v. 35, n. 2, p. 235, doi. 10.1007/s10637-017-0439-y
    By:
    • Almhanna, Khaldoun;
    • Miron, Maria;
    • Wright, David;
    • Gracian, Antonio;
    • Hubner, Richard;
    • Van Laethem, Jean-Luc;
    • López, Carolina;
    • Alsina, Maria;
    • Muñoz, Frederico;
    • Bendell, Johanna;
    • Firdaus, Irfan;
    • Messersmith, Wells;
    • Ye, Zhan;
    • Fasanmade, Adedigbo;
    • Danaee, Hadi;
    • Kalebic, Thea
    Publication type:
    Article
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    Phase I trial of vandetanib in combination with gemcitabine and capecitabine in patients with advanced solid tumors with an expanded cohort in pancreatic and biliary cancers.

    Published in:
    Investigational New Drugs, 2016, v. 34, n. 2, p. 176, doi. 10.1007/s10637-015-0316-5
    By:
    • Kessler, Elizabeth;
    • Eckhardt, S.;
    • Pitts, Todd;
    • Bradshaw-Pierce, Erica;
    • O'byrant, Cindy;
    • Messersmith, Wells;
    • Nallapreddy, Sujatha;
    • Weekes, Colin;
    • Spratlin, Jennifer;
    • Lieu, Christopher;
    • Kane, Madeleine;
    • Eppers, Sarah;
    • Freas, Elizabeth;
    • Leong, Stephen
    Publication type:
    Article
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    Response to radiotherapy in pancreatic ductal adenocarcinoma is enhanced by inhibition of myeloid-derived suppressor cells using STAT3 anti-sense oligonucleotide.

    Published in:
    Cancer Immunology, Immunotherapy, 2021, v. 70, n. 4, p. 989, doi. 10.1007/s00262-020-02701-w
    By:
    • Oweida, Ayman J.;
    • Mueller, Adam C.;
    • Piper, Miles;
    • Milner, Dallin;
    • Van Court, Benjamin;
    • Bhatia, Shilpa;
    • Phan, Andy;
    • Bickett, Thomas;
    • Jordan, Kimberly;
    • Proia, Theresa;
    • Schulick, Richard;
    • Messersmith, Wells A.;
    • Del Chiaro, Marco;
    • Clambey, Eric;
    • Gough, Michael J.;
    • Williams, Jason;
    • Hansen, Kirk;
    • Goodman, Karyn;
    • Karam, Sana D.
    Publication type:
    Article
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    Potent antitumor activity of cabozantinib, a c- MET and VEGFR2 inhibitor, in a colorectal cancer patient-derived tumor explant model.

    Published in:
    International Journal of Cancer, 2015, v. 136, n. 8, p. 1967, doi. 10.1002/ijc.29225
    By:
    • Song, Eun‐Kee;
    • Tai, WM;
    • Messersmith, Wells A.;
    • Bagby, Stacey;
    • Purkey, Alicia;
    • Quackenbush, Kevin S.;
    • Pitts, Todd M.;
    • Wang, Guoliang;
    • Blatchford, Patrick;
    • Yahn, Rachel;
    • Kaplan, Jeffrey;
    • Tan, Aik Choon;
    • Atreya, Chloe E.;
    • Eckhardt, Gail;
    • Kelley, Robin K.;
    • Venook, Alan;
    • Kwak, Eunice L.;
    • Ryan, David;
    • Arcaroli, John J.
    Publication type:
    Article
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    A Phase Ib Expansion Cohort Evaluating Aurora A Kinase Inhibitor Alisertib and Dual TORC1/2 Inhibitor Sapanisertib in Patients with Advanced Solid Tumors.

    Published in:
    Cancers, 2024, v. 16, n. 8, p. 1456, doi. 10.3390/cancers16081456
    By:
    • Davis, S. Lindsey;
    • Messersmith, Wells A.;
    • Purcell, W. Thomas;
    • Lam, Elaine T.;
    • Corr, Bradley R.;
    • Leal, Alexis D.;
    • Lieu, Christopher H.;
    • O'Bryant, Cindy L.;
    • Smoots, Stephen G.;
    • Dus, Evan D.;
    • Jordan, Kimberly R.;
    • Serkova, Natalie J.;
    • Pitts, Todd M.;
    • Diamond, Jennifer R.
    Publication type:
    Article
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    Examination of Wnt signaling as a therapeutic target for pancreatic ductal adenocarcinoma (PDAC) using a pancreatic tumor organoid library (PTOL).

    Published in:
    PLoS ONE, 2024, v. 19, n. 4, p. 1, doi. 10.1371/journal.pone.0298808
    By:
    • Hawkins, Hayley J.;
    • Yacob, Betelehem W.;
    • Brown, Monica E.;
    • Goldstein, Brandon R.;
    • Arcaroli, John J.;
    • Bagby, Stacey M.;
    • Hartman, Sarah J.;
    • Macbeth, Morgan;
    • Goodspeed, Andrew;
    • Danhorn, Thomas;
    • Lentz, Robert W.;
    • Lieu, Christopher H.;
    • Leal, Alexis D.;
    • Messersmith, Wells A.;
    • Dempsey, Peter J.;
    • Pitts, Todd M.
    Publication type:
    Article
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    HER2-Positive Metastatic Colorectal Cancer.

    Published in:
    Current Treatment Options in Oncology, 2024, v. 25, n. 5, p. 585, doi. 10.1007/s11864-024-01183-7
    By:
    • Robinson, Hannah R.;
    • Messersmith, Wells A.;
    • Lentz, Robert W.
    Publication type:
    Article
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    Combined inhibition of MEK and Aurora A kinase in KRAS/PIK3CA double-mutant colorectal cancer models.

    Published in:
    Frontiers in Pharmacology, 2015, p. 1, doi. 10.3389/fphar.2015.00120
    By:
    • Davis, S. Lindsey;
    • Robertson, Kelli M.;
    • Pitts, Todd M.;
    • Tentler, John J.;
    • Bradshaw-Pierce, Erica L.;
    • Klauck, Peter J.;
    • Bagby, Stacey M.;
    • Hyatt, Stephanie L.;
    • Selby, Heather M.;
    • Spreafico, Anna;
    • Ecsedy, Jeffrey A.;
    • Arcaroli, John J.;
    • Messersmith, Wells A.;
    • Aik Choon Tan;
    • Eckhardt, S. Gail;
    • Yongmei Song;
    • Smaglo, Brandon George;
    • Astsaturov, Igor
    Publication type:
    Article
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