Works matching AU Mergny, Jean-Louis

Results: 144

Ligand Binding to Dynamically Populated G‐Quadruplex DNA.

Published in:

ChemBioChem, 2021, v. 22, n. 10, p. 1811, doi. 10.1002/cbic.202000792

By:

Aznauryan, Mikayel;
Noer, Sofie Louise;
Pedersen, Camilla W.;
Mergny, Jean‐Louis;
Teulade‐Fichou, Marie‐Paule;
Birkedal, Victoria

Publication type:

Article

An Acyclic Oligoheteroaryle That Discriminates Strongly between Diverse G-Quadruplex Topologies.

Published in:

Angewandte Chemie, 2011, v. 123, n. 37, p. 8904, doi. 10.1002/ange.201103422

By:

Hamon, Florian;
Largy, Eric;
Guédin-Beaurepaire, Aurore;
Rouchon-Dagois, Myriam;
Sidibe, Assitan;
Monchaud, David;
Mergny, Jean-Louis;
Riou, Jean-Francois;
Nguyen, Chi-Hung;
Teulade-Fichou, Marie-Paule

Publication type:

Article

Portrait of a Family of Highly Stabilizing and Selective Guanine Quadruplex Platinum(II)‐Based Binders.

Published in:

Chemistry - A European Journal, 2022, v. 28, n. 7, p. 1, doi. 10.1002/chem.202103839

By:

Miron, Caitlin E.;
Chen, Mickey;
Mergny, Jean‐Louis;
Petitjean, Anne

Publication type:

Article

G‐Quadruplex Formation by DNA Sequences Deficient in Guanines: Two Tetrad Parallel Quadruplexes Do Not Fold Intramolecularly.

Published in:

Chemistry - A European Journal, 2021, v. 27, n. 47, p. 12115, doi. 10.1002/chem.202100895

By:

Kejnovská, Iva;
Stadlbauer, Petr;
Trantírek, Lukáš;
Renčiuk, Daniel;
Gajarský, Martin;
Krafčík, Daniel;
Palacký, Jan;
Bednářová, Klára;
Šponer, Jiří;
Mergny, Jean‐Louis;
Vorlíčková, Michaela

Publication type:

Article

DNA Quadruplex Structure with a Unique Cation Dependency.

Published in:

Angewandte Chemie, 2024, v. 136, n. 7, p. 1, doi. 10.1002/ange.202313226

By:

Gajarsky, Martin;
Stadlbauer, Petr;
Sponer, Jiri;
Cucchiarini, Anne;
Dobrovolna, Michaela;
Brazda, Vaclav;
Mergny, Jean‐Louis;
Trantirek, Lukas;
Lenarcic Zivkovic, Martina

Publication type:

Article

Effects of Sequence and Base Composition on the CD and TDS Profiles of i‐DNA.

Published in:

Angewandte Chemie, 2021, v. 133, n. 18, p. 10383, doi. 10.1002/ange.202016822

By:

Iaccarino, Nunzia;
Cheng, Mingpan;
Qiu, Dehui;
Pagano, Bruno;
Amato, Jussara;
Di Porzio, Anna;
Zhou, Jun;
Randazzo, Antonio;
Mergny, Jean‐Louis

Publication type:

Article

Thermal and pH Stabilities of i‐DNA: Confronting in vitro Experiments with Models and In‐Cell NMR Data.

Published in:

Angewandte Chemie, 2021, v. 133, n. 18, p. 10374, doi. 10.1002/ange.202016801

By:

Cheng, Mingpan;
Qiu, Dehui;
Tamon, Liezel;
Ištvánková, Eva;
Víšková, Pavlína;
Amrane, Samir;
Guédin, Aurore;
Chen, Jielin;
Lacroix, Laurent;
Ju, Huangxian;
Trantírek, Lukáš;
Sahakyan, Aleksandr B.;
Zhou, Jun;
Mergny, Jean‐Louis

Publication type:

Article

Going Platinum to the Tune of a Remarkable Guanine Quadruplex Binder: Solution‐ and Solid‐State Investigations.

Published in:

Angewandte Chemie, 2021, v. 133, n. 5, p. 2530, doi. 10.1002/ange.202012520

By:

Miron, Caitlin E.;
Staalduinen, Laura;
Rangaswamy, Alana M.;
Chen, Mickey;
Liang, Yushi;
Jia, Zongchao;
Mergny, Jean‐Louis;
Petitjean, Anne

Publication type:

Article

Design, Synthesis, and In Vitro Antimalarial Evaluation of New 1,3,5- Tris [(4-(Substituted-Aminomethyl)Phenoxy)Methyl]Benzenes.

Published in:

Drugs & Drug Candidates, 2024, v. 3, n. 3, p. 615, doi. 10.3390/ddc3030035

By:

Albenque-Rubio, Sandra;
Guillon, Jean;
Agnamey, Patrice;
Damiani, Céline;
Savrimoutou, Solène;
Mustière, Romain;
Pinaud, Noël;
Moreau, Stéphane;
Mergny, Jean-Louis;
Ronga, Luisa;
Kanavos, Ioannis;
Marchivie, Mathieu;
Moukha, Serge;
Dozolme, Pascale;
Sonnet, Pascal;
Cohen, Anita

Publication type:

Article

Synthesis and Antimalarial Evaluation of New 1,3,5- tris [(4-(Substituted-aminomethyl)phenyl)methyl]benzene Derivatives: A Novel Alternative Antiparasitic Scaffold.

Published in:

Drugs & Drug Candidates, 2023, v. 2, n. 3, p. 653, doi. 10.3390/ddc2030033

By:

Albenque-Rubio, Sandra;
Guillon, Jean;
Cohen, Anita;
Agnamey, Patrice;
Savrimoutou, Solène;
Moreau, Stéphane;
Mergny, Jean-Louis;
Ronga, Luisa;
Kanavos, Ioannis;
Moukha, Serge;
Dozolme, Pascale;
Sonnet, Pascal

Publication type:

Article

Asymmetric distribution of G-quadruplex forming sequences in genomes of retroviruses.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-024-82613-2

By:

Kledus, Filip;
Dobrovolná, Michaela;
Mergny, Jean-Louis;
Brázda, Václav

Publication type:

Article

Interaction of human telomeric DNA with N-methyl mesoporphyrin IX.

Published in:

Nucleic Acids Research, 2012, v. 40, n. 13, p. 5432, doi. 10.1093/nar/gks152

By:

Nicoludis, John M.;
Barrett, Steven P.;
Mergny, Jean-Louis;
Yatsunyk, Liliya A.

Publication type:

Article

Interaction of human telomeric DNA with N-methyl mesoporphyrin IX.

Published in:

Nucleic Acids Research, 2012, v. 40, n. 12, p. 5432, doi. 10.1093/nar/gks152

By:

Nicoludis, John M.;
Barrett, Steven P.;
Mergny, Jean-Louis;
Yatsunyk, Liliya A.

Publication type:

Article

Stability of telomeric G-quadruplexes.

Published in:

Nucleic Acids Research, 2011, v. 39, n. 8, p. 3282, doi. 10.1093/nar/gkq1292

By:

Tran, Phong Lan Thao;
Mergny, Jean-Louis;
Alberti, Patrizia

Publication type:

Article

Fluorescence-based duplex–quadruplex competition test to screen for telomerase RNA quadruplex ligands.

Published in:

Nucleic Acids Research, 2011, v. 39, n. 4, p. e21, doi. 10.1093/nar/gkq1199

By:

Lacroix, Laurent;
Séosse, Aurélie;
Mergny, Jean-Louis

Publication type:

Article

How long is too long? Effects of loop size on G-quadruplex stability.

Published in:

Nucleic Acids Research, 2010, v. 38, n. 21, p. 7858, doi. 10.1093/nar/gkq639

By:

Guédin, Aurore;
Gros, Julien;
Alberti, Patrizia;
Mergny, Jean-Louis

Publication type:

Article

A G-quadruplex structure within the 5′-UTR of TRF2 mRNA represses translation in human cells.

Published in:

Nucleic Acids Research, 2010, v. 38, n. 20, p. 7187, doi. 10.1093/nar/gkq563

By:

Gomez, Dennis;
Guédin, Aurore;
Mergny, Jean-Louis;
Salles, Bernard;
Riou, Jean-François;
Teulade-Fichou, Marie-Paule;
Calsou, Patrick

Publication type:

Article

Sequence variant (CTAGGG)n in the human telomere favors a G-quadruplex structure containing a G·C·G·C tetrad.

Published in:

Nucleic Acids Research, 2009, v. 37, n. 18, p. 6239, doi. 10.1093/nar/gkp630

By:

Lim, Kah Wai;
Alberti, Patrizia;
Guédin, Aurore;
Lacroix, Laurent;
Riou, Jean-François;
Royle, Nicola J.;
Mergny, Jean-Louis;
Phan, Anh Tuân

Publication type:

Article

Human telomeres that contain (CTAGGG)n repeats show replication dependent instability in somatic cells and the male germline.

Published in:

Nucleic Acids Research, 2009, v. 37, n. 18, p. 6225, doi. 10.1093/nar/gkp629

By:

Mendez-Bermudez, Aaron;
Hills, Mark;
Pickett, Hilda A.;
Phan, Anh Tuân;
Mergny, Jean-Louis;
Riou, Jean-François;
Royle, Nicola J.

Publication type:

Article

Stability of intramolecular quadruplexes: sequence effects in the central loop.

Published in:

Nucleic Acids Research, 2009, v. 37, n. 16, p. 5559, doi. 10.1093/nar/gkp563

By:

Guédin, Aurore;
Alberti, Patrizia;
Mergny, Jean-Louis

Publication type:

Article

Guanines are a quartet's best friend: impact of base substitutions on the kinetics and stability of tetramolecular quadruplexes.

Published in:

Nucleic Acids Research, 2007, v. 35, n. 9, p. 3064, doi. 10.1093/nar/gkm111

By:

Gros, Julien;
Rosu, Frédéric;
Amrane, Samir;
De Cian, Anne;
Gabelica, Valérie;
Lacroix, Laurent;
Mergny, Jean-Louis

Publication type:

Article

Quadruplex ligands may act as molecular chaperones for tetramolecular quadruplex formation.

Published in:

Nucleic Acids Research, 2007, v. 35, n. 8, p. 2483, doi. 10.1093/nar/gkm098

By:

Cian, Anne De;
Mergny, Jean-Louis

Publication type:

Article

Human replication protein A unfolds telomeric G-quadruplexes.

Published in:

Nucleic Acids Research, 2006, v. 34, n. 17, p. 4857, doi. 10.1093/nar/gkl564

By:

Salas, Tonatiuh Romero;
Petruseva, Irina;
Lavrik, Olga;
Bourdoncle, Anne;
Mergny, Jean-Louis;
Favre, Alain;
Saintomé, Carole

Publication type:

Article

Kinetics of double-chain reversals bridging contiguous quartets in tetramolecular quadruplexes.

Published in:

Nucleic Acids Research, 2006, v. 34, n. 8, p. 2386, doi. 10.1093/nar/gkl098

By:

Mergny, Jean-Louis;
De Cian, Anne;
Amrane, Samir;
da Silva, Mateus Webba

Publication type:

Article

Thermal difference spectra: a specific signature for nucleic acid structures.

Published in:

Nucleic Acids Research, 2005, v. 33, n. 16, p. e138, doi. 10.1093/nar/gni134

By:

Mergny, Jean-Louis;
Li, Jing;
Lacroix, Laurent;
Amrane, Samir;
Chaires, Jonathan B.

Publication type:

Article

Preferential binding of a G-quadruplex ligand to human chromosome ends.

Published in:

Nucleic Acids Research, 2005, v. 33, n. 13, p. 4182, doi. 10.1093/nar/gki722

By:

Granotier, Christine;
Pennarun, Gaëlle;
Riou, Lydia;
Hoffschir, Françoise;
Gauthier, Laurent R.;
De Cian, Anne;
Gomez, Dennis;
Mandine, Eliane;
Riou, Jean-François;
Mergny, Jean-Louis;
Mailliet, Patrick;
Dutrillaux, Bernard;
Boussin, François D.

Publication type:

Article

Length-dependent energetics of (CTG)<sub>n</sub> and (CAG)<sub>n</sub> trinucleotide repeats.

Published in:

Nucleic Acids Research, 2005, v. 33, n. 13, p. 4065, doi. 10.1093/nar/gki716

By:

Amrane, Samir;
Saccà, Barbara;
Mills, Martin;
Chauhan, Madhu;
Klump, Horst H.;
Mergny, Jean-Louis

Publication type:

Article

The effect of chemical modifications on the thermal stability of different G-quadruplex-forming oligonucleotides.

Published in:

Nucleic Acids Research, 2005, v. 33, n. 4, p. 1182, doi. 10.1093/nar/gki257

By:

Saccà, Barbara;
Lacroix, Laurent;
Mergny, Jean-Louis

Publication type:

Article

Kinetics of tetramolecular quadruplexes.

Published in:

Nucleic Acids Research, 2005, v. 33, n. 1, p. 81, doi. 10.1093/nar/gki148

By:

Mergny, Jean-Louis;
De Cian, Anne;
Ghelab, Amar;
Saccá, Barbara;
Lacroix, Laurent

Publication type:

Article

Telomerase downregulation induced by the G‐quadruplex ligand 12459 in A549 cells is mediated by hTERT RNA alternative splicing.

Published in:

Nucleic Acids Research, 2004, v. 32, n. 1, p. 371, doi. 10.1093/nar/gkh181

By:

Gomez, Dennis;
Lemarteleur, Thibault;
Lacroix, Laurent;
Mailliet, Patrick;
Mergny, Jean‐Louis;
Riou, Jean‐François

Publication type:

Article

G‐quartets direct assembly of HIV‐1 nucleocapsid protein along single‐stranded DNA.

Published in:

Nucleic Acids Research, 2003, v. 31, n. 19, p. 5754, doi. 10.1093/nar/gkg716

By:

Lyonnais, Sébastien;
Gorelick, Robert J.;
Mergny, Jean‐Louis;
Le Cam, Eric;
Mirambeau, Gilles

Publication type:

Article

A directional nucleation‐zipping mechanism for triple helix formation.

Published in:

Nucleic Acids Research, 2002, v. 30, n. 24, p. 5407, doi. 10.1093/nar/gkf675

By:

Alberti, Patrizia;
Arimondo, Paola B.;
Mergny, Jean‐Louis;
Garestier, Thérèse;
Hélène, Claude;
Sun, Jian‐Sheng

Publication type:

Article

Human telomeric DNA: G‐quadruplex, i‐motif and Watson–Crick double helix.

Published in:

Nucleic Acids Research, 2002, v. 30, n. 21, p. 4618, doi. 10.1093/nar/gkf597

By:

Phan, Anh Tuân;
Mergny, Jean‐Louis

Publication type:

Article

Natural and pharmacological regulation of telomerase.

Published in:

Nucleic Acids Research, 2002, v. 30, n. 4, p. 839, doi. 10.1093/nar/30.4.839

By:

Mergny, Jean-Louis;
Riou, Jean-François;
Mailliet, Patrick;
Teulade-Fichou, Marie-Paule;
Gilson, Eric

Publication type:

Article

New 2,4-bis[(substituted-aminomethyl)phenyl]phenylquinazoline and 2,4-bis[(substituted-aminomethyl)phenyl]phenylquinoline Derivatives: Synthesis and Biological Evaluation as Novel Anticancer Agents by Targeting G-Quadruplex.

Published in:

Pharmaceuticals (14248247), 2024, v. 17, n. 1, p. 30, doi. 10.3390/ph17010030

By:

Guillon, Jean;
Le Borgne, Marc;
Milano, Vittoria;
Guédin-Beaurepaire, Aurore;
Moreau, Stéphane;
Pinaud, Noël;
Ronga, Luisa;
Savrimoutou, Solène;
Albenque-Rubio, Sandra;
Marchivie, Mathieu;
Kalout, Haouraa;
Walker, Charley;
Chevallier, Louise;
Buré, Corinne;
Largy, Eric;
Gabelica, Valérie;
Mergny, Jean-Louis;
Baylot, Virginie;
Ferrer, Jacky;
Idrissi, Yamina

Publication type:

Article

TGF‐β‐induced fibrotic stress increases G‐quadruplex formation in human fibroblasts.

Published in:

FEBS Letters, 2019, v. 593, n. 22, p. 3149, doi. 10.1002/1873-3468.13658

By:

Toshniwal, Priyanka;
Nguyen, Michelle;
Guédin, Aurore;
Viola, Helena;
Ho, Diwei;
Kim, Yongeun;
Bhatt, Uditi;
Bond, Charles S.;
Hool, Livia;
Hurley, Laurence H.;
Mergny, Jean‐Louis;
Fear, Mark;
Wood, Fiona;
Iyer, Swaminathan K.;
Smith, Nicole M.

Publication type:

Article

The Yeast Pif1 Helicase Prevents Genomic Instability Caused by G-Quadruplex-Forming CEB1 Sequences In Vivo.

Published in:

PLoS Genetics, 2009, v. 5, n. 5, p. 1, doi. 10.1371/journal.pgen.1000475

By:

Ribeyre, Cyril;
Lopes, Judith;
Boulé, Jean-Baptiste;
Piazza, Aurèle;
Guédin, Aurore;
Zakian, Virginia A.;
Mergny, Jean-Louis;
Nicolas, Alain

Publication type:

Article

Design, synthesis and antimalarial activity of novel bis{ N -[(pyrrolo[1,2- a ]quinoxalin-4-yl)benzyl]-3-aminopropyl}amine derivatives.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2017, v. 32, n. 1, p. 547, doi. 10.1080/14756366.2016.1268608

By:

Guillon, Jean;
Cohen, Anita;
Gueddouda, Nassima Meriem;
Das, Rabindra Nath;
Moreau, Stéphane;
Ronga, Luisa;
Savrimoutou, Solène;
Basmaciyan, Louise;
Monnier, Alix;
Monget, Myriam;
Rubio, Sandra;
Garnerin, Timothée;
Azas, Nadine;
Mergny, Jean-Louis;
Mullié, Catherine;
Sonnet, Pascal

Publication type:

Article

Tri-G-Quadruplex: Controlled Assembly of a G-Quadruplex Structure from Three G-Rich Strands.

Published in:

Angewandte Chemie International Edition, 2012, v. 51, n. 44, p. 11002, doi. 10.1002/anie.201205390

By:

Zhou, Jun;
Bourdoncle, Anne;
Rosu, Frédéric;
Gabelica, Valérie;
Mergny, Jean-Louis

Publication type:

Article

An Acyclic Oligoheteroaryle That Discriminates Strongly between Diverse G-Quadruplex Topologies.

Published in:

Angewandte Chemie International Edition, 2011, v. 50, n. 37, p. 8745, doi. 10.1002/anie.201103422

By:

Hamon, Florian;
Largy, Eric;
Guédin-Beaurepaire, Aurore;
Rouchon-Dagois, Myriam;
Sidibe, Assitan;
Monchaud, David;
Mergny, Jean-Louis;
Riou, Jean-Francois;
Nguyen, Chi-Hung;
Teulade-Fichou, Marie-Paule

Publication type:

Article

Engineering Bisquinolinium/Thiazole Orange Conjugates for Fluorescent Sensing of G-Quadruplex DNA.

Published in:

Angewandte Chemie International Edition, 2009, v. 48, n. 12, p. 2188, doi. 10.1002/anie.200805613

By:

Yang, Peng;
De Cian, Anne;
Teulade-Fichou, Marie-Paule;
Mergny, Jean-Louis;
Monchaud, David

Publication type:

Article

A Metal-Mediated Conformational Switch Controls G-Quadruplex Binding Affinity.

Published in:

Angewandte Chemie International Edition, 2008, v. 47, n. 26, p. 4858, doi. 10.1002/anie.200800468

By:

Monchaud, David;
Yang, Peng;
Lacroix, Laurent;
Teulade-Fichou, Marie-Paule;
Mergny, Jean-Louis

Publication type:

Article

The Newly Sequenced Genome of Pisum sativum Is Replete with Potential G-Quadruplex-Forming Sequences—Implications for Evolution and Biological Regulation.

Published in:

International Journal of Molecular Sciences, 2022, v. 23, n. 15, p. 8482, doi. 10.3390/ijms23158482

By:

Dobrovolná, Michaela;
Bohálová, Natália;
Peška, Vratislav;
Wang, Jiawei;
Luo, Yu;
Bartas, Martin;
Volná, Adriana;
Mergny, Jean-Louis;
Brázda, Václav

Publication type:

Article

Quartets in G-major. The First International Meeting on Quadruplex DNA.

Published in:

EMBO Reports, 2007, v. 8, n. 11, p. 1003, doi. 10.1038/sj.embor.7401073

By:

Bates, Paula;
Mergny, Jean-Louis;
Yang, Danzhou

Publication type:

Article

Screening of Scaffolds for the Design of G-Quadruplex Ligands.

Published in:

Applied Sciences (2076-3417), 2022, v. 12, n. 4, p. 2170, doi. 10.3390/app12042170

By:

Figueiredo, Joana;
Peitinho, David;
Campello, Maria Paula Cabral;
Oliveira, Maria Cristina;
Paulo, António;
Mergny, Jean-Louis;
Cruz, Carla

Publication type:

Article

DNA Quadruplex Structure with a Unique Cation Dependency.

Published in:

Angewandte Chemie International Edition, 2024, v. 63, n. 7, p. 1, doi. 10.1002/anie.202313226

By:

Gajarsky, Martin;
Stadlbauer, Petr;
Sponer, Jiri;
Cucchiarini, Anne;
Dobrovolna, Michaela;
Brazda, Vaclav;
Mergny, Jean‐Louis;
Trantirek, Lukas;
Lenarcic Zivkovic, Martina

Publication type:

Article

Thermal and pH Stabilities of i‐DNA: Confronting in vitro Experiments with Models and In‐Cell NMR Data.

Published in:

Angewandte Chemie International Edition, 2021, v. 60, n. 18, p. 10286, doi. 10.1002/anie.202016801

By:

Cheng, Mingpan;
Qiu, Dehui;
Tamon, Liezel;
Ištvánková, Eva;
Víšková, Pavlína;
Amrane, Samir;
Guédin, Aurore;
Chen, Jielin;
Lacroix, Laurent;
Ju, Huangxian;
Trantírek, Lukáš;
Sahakyan, Aleksandr B.;
Zhou, Jun;
Mergny, Jean‐Louis

Publication type:

Article

Effects of Sequence and Base Composition on the CD and TDS Profiles of i‐DNA.

Published in:

Angewandte Chemie International Edition, 2021, v. 60, n. 18, p. 10295, doi. 10.1002/anie.202016822

By:

Iaccarino, Nunzia;
Cheng, Mingpan;
Qiu, Dehui;
Pagano, Bruno;
Amato, Jussara;
Di Porzio, Anna;
Zhou, Jun;
Randazzo, Antonio;
Mergny, Jean‐Louis

Publication type:

Article

Going Platinum to the Tune of a Remarkable Guanine Quadruplex Binder: Solution‐ and Solid‐State Investigations.

Published in:

Angewandte Chemie International Edition, 2021, v. 60, n. 5, p. 2500, doi. 10.1002/anie.202012520

By:

Miron, Caitlin E.;
Staalduinen, Laura;
Rangaswamy, Alana M.;
Chen, Mickey;
Liang, Yushi;
Jia, Zongchao;
Mergny, Jean‐Louis;
Petitjean, Anne

Publication type:

Article

G-quadruplex ligands as potent regulators of lysosomes.

Published in:

Autophagy, 2023, v. 19, n. 7, p. 1901, doi. 10.1080/15548627.2023.2170071

By:

Ferret, Lucille;
Alvarez-Valadez, Karla;
Rivière, Jennifer;
Muller, Alexandra;
Bohálová, Natalia;
Yu, Luo;
Guittat, Lionel;
Brázda, Vaclav;
Kroemer, Guido;
Mergny, Jean-Louis;
Djavaheri-Mergny, Mojgan

Publication type:

Article