Works matching AU Mengel-From, Jonas

Results: 45

Effects of the APOE {varepsilon}2 Allele on Mortality and Cognitive Function in the Oldest Old.

Published in:

2013

By:

Lindahl-Jacobsen, Rune;
Tan, Qihua;
Mengel-From, Jonas;
Christensen, Kaare;
Nebel, Almut;
Christiansen, Lene

Publication type:

Journal Article

Effects of the APOE ε2 Allele on Mortality and Cognitive Function in the Oldest Old.

Published in:

Journals of Gerontology Series A: Biological Sciences & Medical Sciences, 2013, v. 68, n. 4, p. 389, doi. 10.1093/gerona/gls192

By:

Lindahl-Jacobsen, Rune;
Tan, Qihua;
Mengel-From, Jonas;
Christensen, Kaare;
Nebel, Almut;
Christiansen, Lene

Publication type:

Article

Genetic and environmental influences on cardiovascular risk factors and cognitive function: A Chinese twin aging study.

Published in:

Geriatrics & Gerontology International, 2018, v. 18, n. 2, p. 352, doi. 10.1111/ggi.13161

By:

Xu, Chunsheng;
Tian, Xiaocao;
Sun, Jianping;
Wu, Yili;
Zhang, Dongfeng;
Pang, Zengchang;
Li, Shuxia;
Petersen, Inge;
Mengel‐From, Jonas;
Christiansen, Lene;
Christensen, Kaare;
Tan, Qihua

Publication type:

Article

Identifying the methyltransferases for m5U747 and m5U1939 in 23S rRNA using MALDI mass spectrometry.

Published in:

Nucleic Acids Research, 2003, v. 31, n. 16, p. 4738, doi. 10.1093/nar/gkg657

By:

Madsen, Christian Toft;
Mengel‐Jørgensen, Jonas;
Kirpekar, Finn;
Douthwaite, Stephen

Publication type:

Article

Detection of pseudouridine and other modifications in tRNA by cyanoethylation and MALDI mass spectrometry.

Published in:

Nucleic Acids Research, 2002, v. 30, n. 23, p. e135

By:

Mengel‐Jørgensen, Jonas;
Kirpekar, Finn

Publication type:

Article

Heritability and circulating concentrations of pregnancy-associated plasma protein-A and stanniocalcin-2 in elderly monozygotic and dizygotic twins.

Published in:

Frontiers in Endocrinology, 2023, p. 01, doi. 10.3389/fendo.2023.1193742

By:

Hjortebjerg, Rikke;
Pedersen, Dorthe Almind;
Mengel-From, Jonas;
Jørgensen, Louise Helskov;
Christensen, Kaare;
Frystyk, Jan

Publication type:

Article

Human longevity and variation in DNA damage response and repair: study of the contribution of sub-processes using competitive gene-set analysis.

Published in:

European Journal of Human Genetics, 2014, v. 22, n. 9, p. 1131, doi. 10.1038/ejhg.2013.299

By:

Debrabant, Birgit;
Soerensen, Mette;
Flachsbart, Friederike;
Dato, Serena;
Mengel-From, Jonas;
Stevnsner, Tinna;
Bohr, Vilhelm A;
Kruse, Torben A;
Schreiber, Stefan;
Nebel, Almut;
Christensen, Kaare;
Tan, Qihua;
Christiansen, Lene

Publication type:

Article

AKT1 fails to replicate as a longevity-associated gene in Danish and German nonagenarians and centenarians.

Published in:

European Journal of Human Genetics, 2013, v. 21, n. 5, p. 574, doi. 10.1038/ejhg.2012.196

By:

Nygaard, Marianne;
Soerensen, Mette;
Flachsbart, Friederike;
Mengel-From, Jonas;
Tan, Qihua;
Schreiber, Stefan;
Nebel, Almut;
Christensen, Kaare;
Christiansen, Lene

Publication type:

Article

Skewed X inactivation and survival: a 13-year follow-up study of elderly twins and singletons.

Published in:

European Journal of Human Genetics, 2012, v. 20, n. 3, p. 361, doi. 10.1038/ejhg.2011.215

By:

Mengel-From, Jonas;
Thinggaard, Mikael;
Christiansen, Lene;
Vaupel, James W;
Ørstavik, Karen Helene;
Christensen, Kaare

Publication type:

Article

Tattoo ink exposure is associated with lymphoma and skin cancers – a Danish study of twins.

Published in:

BMC Public Health, 2025, v. 25, n. 1, p. 1, doi. 10.1186/s12889-025-21413-3

By:

Clemmensen, Signe Bedsted;
Mengel-From, Jonas;
Kaprio, Jaakko;
Frederiksen, Henrik;
von Bornemann Hjelmborg, Jacob

Publication type:

Article

Cohort Differences in the Associations of Selected Candidate Genes With Risk of All-Cause Mortality at Advanced Ages.

Published in:

American Journal of Epidemiology, 2020, v. 189, n. 7, p. 708, doi. 10.1093/aje/kwaa007

By:

Tan, Qihua;
Jacobsen, Rune;
Nygaard, Marianne;
Soerensen, Mette;
Mengel-From, Jonas;
Christiansen, Lene;
Christensen, Kaare

Publication type:

Article

Genome-Wide Epistatic Network Analyses of Semantic Fluency in Older Adults.

Published in:

International Journal of Molecular Sciences, 2024, v. 25, n. 10, p. 5257, doi. 10.3390/ijms25105257

By:

Tan, Qihua;
Li, Weilong;
Nygaard, Marianne;
An, Ping;
Feitosa, Mary;
Wojczynski, Mary K.;
Zmuda, Joseph;
Arbeev, Konstantin;
Ukraintseva, Svetlana;
Yashin, Anatoliy;
Christensen, Kaare;
Mengel-From, Jonas

Publication type:

Article

A Mass Spectrometry-Based Proteome Study of Twin Pairs Discordant for Incident Acute Myocardial Infarction within Three Years after Blood Sampling Suggests Novel Biomarkers.

Published in:

International Journal of Molecular Sciences, 2024, v. 25, n. 5, p. 2638, doi. 10.3390/ijms25052638

By:

Beck, Hans Christian;
Skovgaard, Asmus Cosmos;
Mohammadnejad, Afsaneh;
Palstrøm, Nicolai Bjødstrup;
Nielsen, Palle Fruekilde;
Mengel-From, Jonas;
Hjelmborg, Jacob;
Rasmussen, Lars Melholt;
Soerensen, Mette

Publication type:

Article

A Genome-Wide Association Study of 2304 Extreme Longevity Cases Identifies Novel Longevity Variants.

Published in:

International Journal of Molecular Sciences, 2023, v. 24, n. 1, p. 116, doi. 10.3390/ijms24010116

By:

Bae, Harold;
Gurinovich, Anastasia;
Karagiannis, Tanya T.;
Song, Zeyuan;
Leshchyk, Anastasia;
Li, Mengze;
Andersen, Stacy L.;
Arbeev, Konstantin;
Yashin, Anatoliy;
Zmuda, Joseph;
An, Ping;
Feitosa, Mary;
Giuliani, Cristina;
Franceschi, Claudio;
Garagnani, Paolo;
Mengel-From, Jonas;
Atzmon, Gil;
Barzilai, Nir;
Puca, Annibale;
Schork, Nicholas J.

Publication type:

Article

Long-Lived Individuals Show a Lower Burden of Variants Predisposing to Age-Related Diseases and a Higher Polygenic Longevity Score.

Published in:

International Journal of Molecular Sciences, 2022, v. 23, n. 18, p. N.PAG, doi. 10.3390/ijms231810949

By:

Torres, Guillermo G.;
Dose, Janina;
Hasenbein, Tim P.;
Nygaard, Marianne;
Krause-Kyora, Ben;
Mengel-From, Jonas;
Christensen, Kaare;
Andersen-Ranberg, Karen;
Kolbe, Daniel;
Lieb, Wolfgang;
Laudes, Matthias;
Görg, Siegfried;
Schreiber, Stefan;
Franke, Andre;
Caliebe, Amke;
Kuhlenbäumer, Gregor;
Nebel, Almut

Publication type:

Article

Global Gene Expression Profiling and Transcription Factor Network Analysis of Cognitive Aging in Monozygotic Twins.

Published in:

Frontiers in Genetics, 2021, v. 11, p. 1, doi. 10.3389/fgene.2021.675587

By:

Mohammadnejad, Afsaneh;
Li, Weilong;
Lund, Jesper Beltoft;
Li, Shuxia;
Larsen, Martin J.;
Mengel-From, Jonas;
Michel, Tanja Maria;
Christiansen, Lene;
Christensen, Kaare;
Hjelmborg, Jacob;
Baumbach, Jan;
Tan, Qihua

Publication type:

Article

Age-Dependent DNA Methylation Variability on the X-Chromosome in Male and Female Twins.

Published in:

Epigenomes, 2024, v. 8, n. 4, p. 43, doi. 10.3390/epigenomes8040043

By:

Tan, Qihua;
Alo, Hikmat;
Nygaard, Marianne;
Sørensen, Mette;
Saleh, Alisa;
Mengel-From, Jonas;
Christensen, Kaare

Publication type:

Article

Sex and age specific reduction in stress resistance and mitochondrial DNA copy number in Drosophila melanogaster.

Published in:

Scientific Reports, 2019, v. 9, n. 1, p. N.PAG, doi. 10.1038/s41598-019-48752-7

By:

Kristensen, Torsten Nygaard;
Loeschcke, Volker;
Tan, Qihua;
Pertoldi, Cino;
Mengel-From, Jonas

Publication type:

Article

The Danish Twin Registry: An Updated Overview.

Published in:

2019

By:

Pedersen, Dorthe Almind;
Larsen, Lisbeth Aagaard;
Nygaard, Marianne;
Mengel-From, Jonas;
McGue, Matt;
Dalgård, Christine;
Hvidberg, Lars;
Hjelmborg, Jacob;
Skytthe, Axel;
Holm, Niels V.;
Kyvik, Kirsten Ohm;
Christensen, Kaare

Publication type:

journal article

Molecular markers of DNA repair and brain metabolism correlate with cognition in centenarians.

Published in:

GeroScience, 2022, v. 44, n. 1, p. 103, doi. 10.1007/s11357-021-00502-2

By:

Sanchez-Roman, Ines;
Ferrando, Beatriz;
Holst, Camilla Myrup;
Mengel-From, Jonas;
Rasmussen, Signe Høi;
Thinggaard, Mikael;
Bohr, Vilhelm A.;
Christensen, Kaare;
Stevnsner, Tinna

Publication type:

Article

Age patterns of intra‐pair DNA methylation discordance in twins: Sex difference in epigenomic instability and implication on survival.

Published in:

Aging Cell, 2021, v. 20, n. 9, p. 1, doi. 10.1111/acel.13460

By:

Tan, Qihua;
Li, Shuxia;
Sørensen, Mette;
Nygaard, Marianne;
Mengel‐From, Jonas;
Christensen, Kaare

Publication type:

Article

Novel DNA methylation marker discovery by assumption‐free genome‐wide association analysis of cognitive function in twins.

Published in:

Aging Cell, 2021, v. 20, n. 2, p. 1, doi. 10.1111/acel.13293

By:

Mohammadnejad, Afsaneh;
Soerensen, Mette;
Baumbach, Jan;
Mengel‐From, Jonas;
Li, Weilong;
Lund, Jesper;
Li, Shuxia;
Christiansen, Lene;
Christensen, Kaare;
Hjelmborg, Jacob V. B.;
Tan, Qihua

Publication type:

Article

Age‐dependent DNA methylation patterns on the Y chromosome in elderly males.

Published in:

Aging Cell, 2020, v. 19, n. 2, p. N.PAG, doi. 10.1111/acel.12907

By:

Lund, Jesper B.;
Li, Shuxia;
Christensen, Kaare;
Mengel‐From, Jonas;
Soerensen, Mette;
Marioni, Riccardo E.;
Starr, John;
Pattie, Alison;
Deary, Ian J.;
Baumbach, Jan;
Tan, Qihua

Publication type:

Article

Markers of Mitochondrial Function and DNA Repair Associated with Physical Function in Centenarians.

Published in:

Biomolecules (2218-273X), 2024, v. 14, n. 8, p. 909, doi. 10.3390/biom14080909

By:

Sanchez-Roman, Ines;
Ferrando, Beatriz;
Myrup Holst, Camilla;
Mengel-From, Jonas;
Hoei Rasmussen, Signe;
Thinggaard, Mikael;
Bohr, Vilhelm A.;
Christensen, Kaare;
Stevnsner, Tinna

Publication type:

Article

Exploratory analysis of age and sex dependent DNA methylation patterns on the X-chromosome in whole blood samples.

Published in:

Genome Medicine, 2020, v. 12, n. 1, p. 1, doi. 10.1186/s13073-020-00736-3

By:

Li, Shuxia;
Lund, Jesper B.;
Christensen, Kaare;
Baumbach, Jan;
Mengel-From, Jonas;
Kruse, Torben;
Li, Weilong;
Mohammadnejad, Afsaneh;
Pattie, Alison;
Marioni, Riccardo E.;
Deary, Ian J.;
Tan, Qihua

Publication type:

Article

Correction to: A nonsynonymous mutation in PLCG2 reduces the risk of Alzheimer's disease, dementia with Lewy bodies and frontotemporal dementia, and increases the likelihood of longevity.

Published in:

2020

By:

van der Lee, Sven J.;
Conway, Olivia J.;
Jansen, Iris;
Carrasquillo, Minerva M.;
Kleineidam, Luca;
van den Akker, Erik;
Hernández, Isabel;
van Eijk, Kristel R.;
Stringa, Najada;
Chen, Jason A.;
Zettergren, Anna;
Andlauer, Till F. M.;
Diez-Fairen, Monica;
Simon-Sanchez, Javier;
Lleó, Alberto;
Zetterberg, Henrik;
Nygaard, Marianne;
Blauwendraat, Cornelis;
Savage, Jeanne E.;
Mengel-From, Jonas

Publication type:

Correction Notice

A nonsynonymous mutation in PLCG2 reduces the risk of Alzheimer's disease, dementia with Lewy bodies and frontotemporal dementia, and increases the likelihood of longevity.

Published in:

Acta Neuropathologica, 2019, v. 138, n. 2, p. 237, doi. 10.1007/s00401-019-02026-8

By:

van der Lee, Sven J.;
Conway, Olivia J.;
Jansen, Iris;
Carrasquillo, Minerva M.;
Kleineidam, Luca;
van den Akker, Erik;
Hernández, Isabel;
van Eijk, Kristel R.;
Stringa, Najada;
Chen, Jason A.;
Zettergren, Anna;
Andlauer, Till F. M.;
Diez-Fairen, Monica;
Simon-Sanchez, Javier;
Lleó, Alberto;
Zetterberg, Henrik;
Nygaard, Marianne;
Blauwendraat, Cornelis;
Savage, Jeanne E.;
Mengel-From, Jonas

Publication type:

Article

Mitochondrial DNA copy number in peripheral blood cells declines with age and is associated with general health among elderly.

Published in:

Human Genetics, 2014, v. 133, n. 9, p. 1149, doi. 10.1007/s00439-014-1458-9

By:

Mengel-From, Jonas;
Thinggaard, Mikael;
Dalgård, Christine;
Kyvik, Kirsten;
Christensen, Kaare;
Christiansen, Lene

Publication type:

Article

Blue eye color in humans may be caused by a perfectly associated founder mutation in a regulatory element located within the HERC2 gene inhibiting OCA2 expression.

Published in:

Human Genetics, 2008, v. 123, n. 2, p. 177, doi. 10.1007/s00439-007-0460-x

By:

Eiberg, Hans;
Troelsen, Jesper;
Nielsen, Mette;
Mikkelsen, Annemette;
Mengel-From, Jonas;
Kjaer, Klaus W.;
Hansen, Lars

Publication type:

Article

Familial Risk and Heritability of Hematologic Malignancies in the Nordic Twin Study of Cancer.

Published in:

Cancers, 2021, v. 13, n. 12, p. 3023, doi. 10.3390/cancers13123023

By:

Clemmensen, Signe B.;
Harris, Jennifer R.;
Mengel-From, Jonas;
Bonat, Wagner H.;
Frederiksen, Henrik;
Kaprio, Jaakko;
Hjelmborg, Jacob v. B.

Publication type:

Article

Determination of cis/trans phase of variations in the MC1R gene with allele-specific PCR and single base extension.

Published in:

Electrophoresis, 2008, v. 29, n. 23, p. 4780, doi. 10.1002/elps.200800107

By:

Mengel-From, Jonas;
Børsting, Claus;
Sanchez, Juan J.;
Eiberg, Hans;
Morling, Niels

Publication type:

Article

Skewness of X-chromosome inactivation increases with age and varies across birth cohorts in elderly Danish women.

Published in:

Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-83702-2

By:

Mengel-From, Jonas;
Lindahl-Jacobsen, Rune;
Nygaard, Marianne;
Soerensen, Mette;
Ørstavik, Karen Helene;
Hertz, Jens Michael;
Andersen-Ranberg, Karen;
Tan, Qihua;
Christensen, Kaare

Publication type:

Article

CLU Genetic Variants and Cognitive Decline among Elderly and Oldest Old.

Published in:

PLoS ONE, 2013, v. 8, n. 11, p. 1, doi. 10.1371/journal.pone.0079105

By:

Mengel-From, Jonas;
Thinggaard, Mikael;
Lindahl-Jacobsen, Rune;
McGue, Matt;
Christensen, Kaare;
Christiansen, Lene

Publication type:

Article

Tattooing is Mainly Cultural: A Representative Twin Study of Tattooing Determinants.

Published in:

Behavior Genetics, 2025, v. 55, n. 2, p. 114, doi. 10.1007/s10519-025-10215-3

By:

Clemmensen, Signe B.;
Mengel-From, Jonas;
Kaprio, Jaakko;
Harris, Jennifer R.;
Frederiksen, Henrik;
von Bornemann Hjelmborg, Jacob

Publication type:

Article

Epigenome-wide exploratory study of monozygotic twins suggests differentially methylated regions to associate with hand grip strength.

Published in:

Biogerontology, 2019, v. 20, n. 5, p. 627, doi. 10.1007/s10522-019-09818-1

By:

Soerensen, Mette;
Li, Weilong;
Debrabant, Birgit;
Nygaard, Marianne;
Mengel-From, Jonas;
Frost, Morten;
Christensen, Kaare;
Christiansen, Lene;
Tan, Qihua

Publication type:

Article

A Review of Major Danish Biobanks: Advantages and Possibilities of Health Research in Denmark.

Published in:

Clinical Epidemiology, 2023, v. 15, p. 213, doi. 10.2147/CLEP.S392416

By:

Laugesen, Kristina;
Mengel-From, Jonas;
Christensen, Kaare;
Olsen, Jørn;
Hougaard, David M;
Boding, Lasse;
Olsen, Anja;
Erikstrup, Christian;
Hetland, Merete Lund;
Høgdall, Estrid;
Kjaergaard, Alisa D;
Sørensen, Erik;
Brügmann, Anja;
Petersen, Eva Rabing Brix;
Brandslund, Ivan;
Nordestgaard, Børge G;
Jensen, Gorm B;
Skajaa, Nils;
Troelsen, Frederikke Schønfeldt;
Fuglsang, Cecilia Hvitfeldt

Publication type:

Article

Identification and replication of gene‐by‐stress interaction associations with Alzheimer's disease and related dementias.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.075970

By:

Singh, Abanish;
Arbeev, Konstantin;
Yashkin, Arseniy Pavlovich;
Mengel‐From, Jonas;
Schupf, Nicole;
Akushevich, Igor;
Yashin, Anatoliy I

Publication type:

Article

Identification and replication of gene‐by‐stress interaction associations with Alzheimer's disease and related dementias.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.075970

By:

Singh, Abanish;
Arbeev, Konstantin;
Yashkin, Arseniy Pavlovich;
Mengel‐From, Jonas;
Schupf, Nicole;
Akushevich, Igor;
Yashin, Anatoliy I

Publication type:

Article

P4‐602: DIGITAL TECHNOLOGY IDENTIFIES DISTINCT PERFORMANCE PATTERNS ON THE DIGIT SYMBOL SUBSTITUTION TEST AMONG COGNITIVELY HEALTHY ADULTS.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P1555, doi. 10.1016/j.jalz.2019.08.150

By:

Andersen, Stacy L.;
Sweigart, Benjamin;
Cosentino, Stephanie;
Wojczynski, Mary K.;
Glynn, Nancy W.;
Thyagarajan, Bharat;
Mengel-From, Jonas;
Thielke, Stephen;
Perls, Thomas T.;
Sebastiani, Paola

Publication type:

Article

Relationship Between Serum IGF-1 and BMI Differs by Age.

Published in:

2021

By:

Sherlala, Rehab A;
Kammerer, Candace M;
Kuipers, Allison L;
Wojczynski, Mary K;
Ukraintseva, Svetlana V;
Feitosa, Mary F;
Mengel-From, Jonas;
Zmuda, Joseph M;
Minster, Ryan L;
Kuiper, Allison L

Publication type:

journal article

Advanced Parental Age at Conception and Sex Affects Mitochondrial DNA Copy Number in Human and Fruit Flies.

Published in:

2019

By:

Mengel-From, Jonas;
Svane, Anne Marie;
Pertoldi, Cino;
Kristensen, Torsten Nygaard;
Loeschcke, Volker;
Skytthe, Axel;
Christensen, Kaare;
Lindahl-Jacobsen, Rune;
Hjelmborg, Jacob;
Christiansen, Lene;
Nygaard Kristensen, Torsten

Publication type:

journal article

Genetic Variants in KLOTHO Associate With Cognitive Function in the Oldest Old Group.

Published in:

2016

By:

Mengel-From, Jonas;
Soerensen, Mette;
Nygaard, Marianne;
McGue, Matt;
Christensen, Kaare;
Christiansen, Lene

Publication type:

journal article

DNA methylation QTL analysis identifies new regulators of human longevity.

Published in:

Human Molecular Genetics, 2020, v. 29, n. 7, p. 1154, doi. 10.1093/hmg/ddaa033

By:

Szymczak, Silke;
Dose, Janina;
Torres, Guillermo G.;
Heinsen, Femke-Anouska;
Venkatesh, Geetha;
Datlinger, Paul;
Nygaard, Marianne;
Mengel-From, Jonas;
Flachsbart, Friederike;
Klapper, Wolfram;
Christensen, Kaare;
Lieb, Wolfgang;
Schreiber, Stefan;
Häsler, Robert;
Bock, Christoph;
Franke, Andre;
Nebel, Almut

Publication type:

Article

Novel epigenetic biomarkers for hematopoietic cancer found in twins.

Published in:

Acta Oncologica, 2024, v. 63, n. 1, p. 710, doi. 10.2340/1651-226X.2024.40700

By:

Clemmensen, Signe B.;
Frederiksen, Henrik;
Mengel-From, Jonas;
Heikkinen, Aino;
Kaprio, Jaakko;
Hjelmborg, Jacob vB.

Publication type:

Article

Genetic and environmental determinants of O6-methylguanine DNA-methyltransferase (MGMT) gene methylation: a 10-year longitudinal study of Danish twins.

Published in:

Clinical Epigenetics, 2021, v. 13, n. 1, p. 1, doi. 10.1186/s13148-021-01009-5

By:

Wang, Lijie;
Mohammadnejad, Afsaneh;
Li, Weilong;
Lund, Jesper;
Li, Shuxia;
Clemmensen, Signe;
Timofeeva, Maria;
Soerensen, Mette;
Mengel-From, Jonas;
Christensen, Kaare;
Hjelmborg, Jacob;
Tan, Qihua

Publication type:

Article