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Proapoptotic activity of JNK-sensitive BH3-only proteins underpins ovarian cancer response to replication checkpoint inhibitors.
Published in:
Molecular Cancer, 2024, v. 23, n. 1, p. 1, doi. 10.1186/s12943-024-02125-5
By:
- Venkatachalam, Annapoorna;
- Correia, Cristina;
- Peterson, Kevin L.;
- Hou, Xianon;
- Schneider, Paula A.;
- Strathman, Annabella R.;
- Flatten, Karen S.;
- Sine, Chance C.;
- Balczewski, Emily A.;
- McGehee, Cordelia D.;
- Larson, Melissa C.;
- Duffield, Laura N.;
- Meng, X. Wei;
- Vincelette, Nicole D.;
- Ding, Husheng;
- Oberg, Ann L.;
- Couch, Fergus J.;
- Swisher, Elizabeth M.;
- Li, Hu;
- Weroha, S. John
Publication type:
Article
Characterization of a RAD51C-silenced high-grade serous ovarian cancer model during development of PARP inhibitor resistance.
Published in:
NAR Cancer, 2021, v. 3, n. 3, p. 1, doi. 10.1093/narcan/zcab028
By:
- Hurley, Rachel M.;
- McGehee, Cordelia D.;
- Nesic, Ksenija;
- Correia, Cristina;
- Weiskittel, Taylor M.;
- Kelly, Rebecca L.;
- Venkatachalam, Annapoorna;
- Xiaonan Hou;
- Pathoulas, Nicholas M.;
- Meng, X. Wei;
- Kondrashova, Olga;
- Radke, Marc R.;
- Schneider, Paula A.;
- Flatten, Karen S.;
- Peterson, Kevin L.;
- Becker, Marc A.;
- Wong, Ee Ming;
- Southey, Melissa S.;
- Dobrovic, Alexander;
- Lin, Kevin K.
Publication type:
Article
Transient binding of an activator BH3 domain to the Bak BH3-binding groove initiates Bak oligomerization.
Published in:
Journal of Cell Biology, 2011, v. 194, n. 1, p. 39, doi. 10.1083/jcb.201102027
By:
- Haiming Dai;
- Smith, Alyson;
- X. Wei Meng;
- Schneider, Paula A.;
- Yuan-Ping Pang;
- Kaufmann, Scott H.
Publication type:
Article
Transient binding of an activator BH3 domain to the Bak BH3-binding groove initiates Bak oligomerization.
Published in:
Journal of Cell Biology, 2011, v. 193, n. 8, p. 39, doi. 10.1083/jcb.201102027
By:
- Haiming Dai;
- Smith, Alyson;
- Meng, X. Wei;
- Schneider, Paula A.;
- Yuan-Ping Pang;
- Kaufmann, Scott H.
Publication type:
Article
Fatty acid synthase (FASN) regulates the mitochondrial priming of cancer cells.
Published in:
Cell Death & Disease, 2021, v. 12, n. 11, p. 1, doi. 10.1038/s41419-021-04262-x
By:
- Schroeder, Barbara;
- Vander Steen, Travis;
- Espinoza, Ingrid;
- Venkatapoorna, Chandra M. Kurapaty;
- Hu, Zeng;
- Silva, Fernando Martín;
- Regan, Kevin;
- Cuyàs, Elisabet;
- Meng, X. Wei;
- Verdura, Sara;
- Arbusà, Aina;
- Schneider, Paula A.;
- Flatten, Karen S.;
- Kemble, George;
- Montero, Joan;
- Kaufmann, Scott H.;
- Menendez, Javier A.;
- Lupu, Ruth
Publication type:
Article
ZNF432 stimulates PARylation and inhibits DNA resection to balance PARPi sensitivity and resistance.
Published in:
Nucleic Acids Research, 2023, v. 51, n. 20, p. 11056, doi. 10.1093/nar/gkad791
By:
- O'Sullivan, Julia;
- Kothari, Charu;
- Caron, Marie-Christine;
- Gagné, Jean-Philippe;
- Jin, Zhigang;
- Nonfoux, Louis;
- Beneyton, Adèle;
- Coulombe, Yan;
- Thomas, Mélissa;
- Atalay, Nurgul;
- Meng, X Wei;
- Milano, Larissa;
- Jean, Dominique;
- Boisvert, François-Michel;
- Kaufmann, Scott H;
- Hendzel, Michael J;
- Masson, Jean-Yves;
- Poirier, Guy G
Publication type:
Article
Characterization of an alternative BAK-binding site for BH3 peptides.
Published in:
Nature Communications, 2020, v. 11, n. 1, p. 1, doi. 10.1038/s41467-020-17074-y
By:
- Ye, Kaiqin;
- Meng, Wei X.;
- Sun, Hongbin;
- Wu, Bo;
- Chen, Meng;
- Pang, Yuan-Ping;
- Gao, Jia;
- Wang, Hongzhi;
- Wang, Junfeng;
- Kaufmann, Scott H.;
- Dai, Haiming
Publication type:
Article

Found: 7

Proapoptotic activity of JNK-sensitive BH3-only proteins underpins ovarian cancer response to replication checkpoint inhibitors.

Characterization of a RAD51C-silenced high-grade serous ovarian cancer model during development of PARP inhibitor resistance.

Transient binding of an activator BH3 domain to the Bak BH3-binding groove initiates Bak oligomerization.

Transient binding of an activator BH3 domain to the Bak BH3-binding groove initiates Bak oligomerization.

Fatty acid synthase (FASN) regulates the mitochondrial priming of cancer cells.

ZNF432 stimulates PARylation and inhibits DNA resection to balance PARPi sensitivity and resistance.

Characterization of an alternative BAK-binding site for BH3 peptides.