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Study protocol for a phase 1/2, single-centre, double-blind, double-dummy, randomized, active-controlled, age de-escalation trial to assess the safety, tolerability and immunogenicity of a measles and rubella vaccine delivered by a microneedle patch in healthy adults (18 to 40 years), measles and rubella vaccine-primed toddlers (15 to 18 months) and measles and rubella vaccine-naïve infants (9 to 10 months) in The Gambia [Measles and Rubella Vaccine Microneedle Patch Phase 1/2 Age De-escalation Trial].
Published in:
2022
By:
Adigweme, Ikechukwu;
Akpalu, Edem;
Yisa, Mohammed;
Donkor, Simon;
Jarju, Lamin B.;
Danso, Baba;
Mendy, Anthony;
Jeffries, David;
Njie, Abdoulie;
Bruce, Andrew;
Royals, Michael;
Goodson, James L.;
Prausnitz, Mark R.;
McAllister, Devin;
Rota, Paul A.;
Henry, Sebastien;
Clarke, Ed
Publication type:
journal article