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Genetic and epigenetic landscape of IDH-wildtype glioblastomas with FGFR3-TACC3 fusions.
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- Acta Neuropathologica Communications, 2020, v. 8, n. 1, p. N.PAG, doi. 10.1186/s40478-020-01058-6
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- Article
Histone-Mutant Glioma: Molecular Mechanisms, Preclinical Models, and Implications for Therapy.
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- International Journal of Molecular Sciences, 2020, v. 21, n. 19, p. 7193, doi. 10.3390/ijms21197193
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- Article
Dual targeting of EGFR can overcome a major drug resistance mutation in mouse models of EGFR mutant lung cancer.
- Published in:
- 2009
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- Publication type:
- journal article
Signal transduction inhibitors and antiangiogenic therapies for malignant glioma.
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- Glia, 2011, v. 59, n. 8, p. 1205, doi. 10.1002/glia.21137
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- Article
Tracing cancer networks with phosphoproteomics.
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- Nature Biotechnology, 2010, v. 28, n. 10, p. 1028, doi. 10.1038/nbt1010-1028
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- Article
Bead-based profiling of tyrosine kinase phosphorylation identifies SRC as a potential target for glioblastoma therapy.
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- Nature Biotechnology, 2009, v. 27, n. 1, p. 77, doi. 10.1038/nbt.1513
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- Publication type:
- Article
A brain tumor molecular imaging strategy using a new triple-modality MRI-photoacoustic-Raman nanoparticle.
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- Nature Medicine, 2012, v. 18, n. 5, p. 829, doi. 10.1038/nm.2721
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- Publication type:
- Article
Hypoxia-inducible factor determines sensitivity to inhibitors of mTOR in kidney cancer.
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- Nature Medicine, 2006, v. 12, n. 1, p. 122, doi. 10.1038/nm1337
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- Article
TORward AKTually useful mouse models.
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- Nature Medicine, 2004, v. 10, n. 6, p. 579, doi. 10.1038/nm0604-579
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- Publication type:
- Article
Somatic mutations of the Parkinson's disease–associated gene PARK2 in glioblastoma and other human malignancies.
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- Nature Genetics, 2010, v. 42, n. 1, p. 77, doi. 10.1038/ng.491
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- Article
Clinical pharmacokinetics and pharmacodynamics of ivosidenib, an oral, targeted inhibitor of mutant IDH1, in patients with advanced solid tumors.
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- Investigational New Drugs, 2020, v. 38, n. 2, p. 433, doi. 10.1007/s10637-019-00771-x
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- Article
Incidence of brain metastases in patients with early HER2-positive breast cancer receiving neoadjuvant chemotherapy with trastuzumab and pertuzumab.
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- NPJ Breast Cancer, 2022, v. 8, n. 1, p. 1, doi. 10.1038/s41523-022-00380-7
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- Article
A Review of Glioblastoma and Other Primary Brain Malignancies—Reply.
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- JAMA: Journal of the American Medical Association, 2023, v. 330, n. 2, p. 189, doi. 10.1001/jama.2023.8590
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- Article
Glioblastoma and Other Primary Brain Malignancies in Adults: A Review.
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- JAMA: Journal of the American Medical Association, 2023, v. 329, n. 7, p. 574, doi. 10.1001/jama.2023.0023
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- Publication type:
- Article
Volumetric analysis of IDH-mutant lower-grade glioma: a natural history study of tumor growth rates before and after treatment.
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- Neuro-Oncology, 2020, v. 22, n. 12, p. 1822, doi. 10.1093/neuonc/noaa105
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- Publication type:
- Article
PI3K pathway inhibition in GBM--is there a signal?
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- Neuro-Oncology, 2015, v. 17, n. 9, p. 1183, doi. 10.1093/neuonc/nov124
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- Publication type:
- Article
Toward precision medicine in glioblastoma: the promise and the challenges.
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- Neuro-Oncology, 2015, v. 17, n. 8, p. 1051, doi. 10.1093/neuonc/nov031
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- Article
Targeted molecular therapies against epidermal growth factor receptor: Past experiences and challenges.
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- Neuro-Oncology, 2014, v. 16, n. suppl_8, p. viii7, doi. 10.1093/neuonc/nou232
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- Article
Brain Malignancy Steering Committee clinical trials planning workshop: Report from the Targeted Therapies Working Group.
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- Neuro-Oncology, 2015, v. 17, n. 2, p. 180, doi. 10.1093/neuonc/nou154
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- Publication type:
- Article
PHASE II TRIAL OF THE PHOSPHATIDYINOSITOL-3 KINASE (PI3K) INHIBITOR BUPARLISIB (BKM120) IN RECURRENT GLIOBLASTOMA CONDUCTED BY THE IVY FOUNDATION EARLY PHASE CLINICAL TRIALS CONSORTIUM.
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- Neuro-Oncology, 2014, v. 16, n. suppl_3, p. iii47, doi. 10.1093/neuonc/nou209.20
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- Publication type:
- Article
Routine use of low-dose glucarpidase following high-dose methotrexate in adult patients with CNS lymphoma: an open-label, multi-center phase I study.
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- 2022
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- Publication type:
- journal article
Glucose deprivation activates a metabolic and signaling amplification loop leading to cell death.
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- Molecular Systems Biology, 2012, v. 8, n. 1, p. 1, doi. 10.1038/msb.2012.20
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- Article
A Mathematical Methodology for Determining the Temporal Order of Pathway Alterations Arising during Gliomagenesis.
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- PLoS Computational Biology, 2012, v. 8, n. 1, p. 1, doi. 10.1371/journal.pcbi.1002337
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- Article
Inferring Loss-of-Heterozygosity from Unpaired Tumors Using High-Density Oligonucleotide SNP Arrays.
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- PLoS Computational Biology, 2006, v. 2, n. 5, p. e41, doi. 10.1371/journal.pcbi.0020041
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- Article
Phase I clinical trial of temsirolimus and perifosine for recurrent glioblastoma.
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- Annals of Clinical & Translational Neurology, 2020, v. 7, n. 4, p. 429, doi. 10.1002/acn3.51009
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- Article
Glutamine-based PET imaging facilitates enhanced metabolic evaluation of gliomas in vivo.
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- Science Translational Medicine, 2015, v. 7, n. 274, p. 1, doi. 10.1126/scitranslmed.aaa1009
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- Article
Prognostic and radiographic correlates of a prospectively collected molecularly profiled cohort of IDH1/2‐wildtype astrocytomas.
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- Brain Pathology, 2020, v. 30, n. 3, p. 653, doi. 10.1111/bpa.12826
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- Article
Pharmacokinetic assessment of <sup>18</sup>F-(2S,4R)-4-fluoroglutamine in patients with cancer.
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- Journal of Nuclear Medicine, 2019, v. 60, n. 12, p. 1, doi. 10.2967/jnumed.119.229740
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- Article
Imaging Tumor Burden in the Brain with <sup>89</sup>Zr-Transferrin.
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- Journal of Nuclear Medicine, 2013, v. 54, n. 1, p. 90, doi. 10.2967/jnumed.112.109777
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- Article
CDKN2A/B mutations and allele-specific alterations stratify survival outcomes in IDH-mutant astrocytomas.
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- Acta Neuropathologica, 2023, v. 146, n. 6, p. 845, doi. 10.1007/s00401-023-02639-0
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- Article
IDH1 mutation is sufficient to establish the glioma hypermethylator phenotype.
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- Nature, 2012, v. 483, n. 7390, p. 479, doi. 10.1038/nature10866
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- Article
IDH mutation impairs histone demethylation and results in a block to cell differentiation.
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- Nature, 2012, v. 483, n. 7390, p. 474, doi. 10.1038/nature10860
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- Article
EGFR feedback-inhibition by Ran-binding protein 6 is disrupted in cancer.
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- Nature Communications, 2017, v. 8, n. 1, p. 1, doi. 10.1038/s41467-017-02185-w
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- Article
Phase II trial of an AKT inhibitor (perifosine) for recurrent glioblastoma.
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- Journal of Neuro-Oncology, 2019, v. 144, n. 2, p. 403, doi. 10.1007/s11060-019-03243-7
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- Article
The biological significance of tumor grade, age, enhancement, and extent of resection in IDH-mutant gliomas: How should they inform treatment decisions in the era of IDH inhibitors?
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- Neuro-Oncology, 2024, v. 26, n. 10, p. 1805, doi. 10.1093/neuonc/noae107
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- Article
Isocitrate dehydrogenase (IDH) mutant gliomas: A Society for Neuro-Oncology (SNO) consensus review on diagnosis, management, and future directions.
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- Neuro-Oncology, 2023, v. 25, n. 1, p. 4, doi. 10.1093/neuonc/noac207
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- Publication type:
- Article
Phase III trial of chemoradiotherapy with temozolomide plus nivolumab or placebo for newly diagnosed glioblastoma with methylated MGMT promoter.
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- Neuro-Oncology, 2022, v. 24, n. 11, p. 1935, doi. 10.1093/neuonc/noac116
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- Publication type:
- Article
Hypothetical generalized framework for a new imaging endpoint of therapeutic activity in early phase clinical trials in brain tumors.
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- Neuro-Oncology, 2022, v. 24, n. 8, p. 1219, doi. 10.1093/neuonc/noac086
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- Publication type:
- Article
Liquid biopsy in gliomas: A RANO review and proposals for clinical applications.
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- Neuro-Oncology, 2022, v. 24, n. 6, p. 855, doi. 10.1093/neuonc/noac004
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- Publication type:
- Article
Volumetric measurements are preferred in the evaluation of mutant IDH inhibition in non-enhancing diffuse gliomas: Evidence from a phase I trial of ivosidenib.
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- Neuro-Oncology, 2022, v. 24, n. 5, p. 770, doi. 10.1093/neuonc/noab256
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- Article
Treatment of Scedosporium apiospermum Brain Abscesses with Posaconazole.
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- Clinical Infectious Diseases, 2002, v. 34, n. 12, p. 1648, doi. 10.1086/340522
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- Article
Prognostic value of [<sup>18</sup>F]FDG PET/CT in patients with CNS lymphoma receiving ibrutinib-based therapies.
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- European Journal of Nuclear Medicine & Molecular Imaging, 2021, v. 48, n. 12, p. 3940, doi. 10.1007/s00259-021-05386-0
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- Publication type:
- Article
Akt Phosphorylates the Transcriptional Repressor Bmi1 to Block Its Effects on the Tumor-Suppressing Ink4a-Arf Locus.
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- Science Signaling, 2012, v. 5, n. 247, p. 1, doi. 10.1126/scisignal.2003199
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- Article
Monitoring Antiproliferative Responses to Kinase Inhibitor Therapy in Mice with 3'-Deoxy-3'-<sup>18</sup>F-Fluorothymidine PET.
- Published in:
- Journal of Nuclear Medicine, 2005, v. 46, n. 1, p. 114
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- Publication type:
- Article