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Proteolysis Targeting Chimera (PROTAC) for Macrophage Migration Inhibitory Factor (MIF) Has Anti‐Proliferative Activity in Lung Cancer Cells.
Published in:
Angewandte Chemie, 2021, v. 133, n. 32, p. 17655, doi. 10.1002/ange.202101864
By:
- Xiao, Zhangping;
- Song, Shanshan;
- Chen, Deng;
- Merkerk, Ronald;
- Wouden, Petra E.;
- Cool, Robbert H.;
- Quax, Wim J.;
- Poelarends, Gerrit J.;
- Melgert, Barbro N.;
- Dekker, Frank J.
Publication type:
Article
Substrate stiffness engineered to replicate disease conditions influence senescence and fibrotic responses in primary lung fibroblasts.
Published in:
Frontiers in Pharmacology, 2022, v. 13, p. 1, doi. 10.3389/fphar.2022.989169
By:
- Blokland, Kaj E. C.;
- Nizamoglu, Mehmet;
- Habibie, Habibie;
- Borghuis, Theo;
- Schuliga, Michael;
- Melgert, Barbro N.;
- Knight, Darryl A.;
- Brandsma, Corry-Anke;
- Pouwels, Simon D.;
- Burgess, Janette K.
Publication type:
Article
Highway to heal: Influence of altered extracellular matrix on infiltrating immune cells during acute and chronic lung diseases.
Published in:
Frontiers in Pharmacology, 2022, v. 13, p. 1, doi. 10.3389/fphar.2022.995051
By:
- Joglekar, Mugdha M.;
- Nizamoglu, Mehmet;
- YiWen Fan;
- Priya Nemani, Sai Sneha;
- Weckmann, Markus;
- Pouwels, Simon D.;
- Heijink, Irene H.;
- Melgert, Barbro N.;
- Pillay, Janesh;
- Burgess, Janette K.
Publication type:
Article
Osteoprotegerin Is more than a Possible Serum Marker in Liver Fibrosis: A Study into Its Function in Human and Murine Liver.
Published in:
Pharmaceutics, 2020, v. 12, n. 5, p. 471, doi. 10.3390/pharmaceutics12050471
By:
- Adhyatmika, Adhyatmika;
- Beljaars, Leonie;
- Putri, Kurnia S. S.;
- Habibie, Habibie;
- Boorsma, Carian E.;
- Reker-Smit, Catharina;
- Luangmonkong, Theerut;
- Guney, Burak;
- Haak, Axel;
- Mangnus, Keri A.;
- Post, Eduard;
- Poelstra, Klaas;
- Ravnskjaer, Kim;
- Olinga, Peter;
- Melgert, Barbro N.
Publication type:
Article
Macrophage--stroma interactions in fibrosis: biochemical, biophysical, and cellular perspectives.
Published in:
Journal of Pathology, 2021, v. 254, n. 4, p. 344, doi. 10.1002/path.5632
By:
- Vasse, Gwenda F.;
- Nizamoglu, Mehmet;
- Heijink, Irene H.;
- Schlepütz, Marco;
- van Rijn, Patrick;
- Thomas, Matthew J.;
- Burgess, Janette K.;
- Melgert, Barbro N.
Publication type:
Article
Macrophage–stroma interactions in fibrosis: biochemical, biophysical, and cellular perspectives.
Published in:
Journal of Pathology, 2021, v. 254, n. 3, p. 344, doi. 10.1002/path.5632
By:
- Vasse, Gwenda F;
- Nizamoglu, Mehmet;
- Heijink, Irene H;
- Schlepütz, Marco;
- Rijn, Patrick;
- Thomas, Matthew J;
- Burgess, Janette K;
- Melgert, Barbro N
Publication type:
Article
Collagen type I alters the proteomic signature of macrophages in a collagen morphology-dependent manner.
Published in:
Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-32715-0
By:
- Vasse, Gwenda F.;
- Russo, Sara;
- Barcaru, Andrei;
- Oun, Asmaa A. A.;
- Dolga, Amalia M.;
- van Rijn, Patrick;
- Kwiatkowski, Marcel;
- Govorukhina, Natalia;
- Bischoff, Rainer;
- Melgert, Barbro N.
Publication type:
Article
Meta-Inflammation and Metabolic Reprogramming of Macrophages in Diabetes and Obesity: The Importance of Metabolites.
Published in:
Frontiers in Immunology, 2021, v. 12, p. 1, doi. 10.3389/fimmu.2021.746151
By:
- Russo, Sara;
- Kwiatkowski, Marcel;
- Govorukhina, Natalia;
- Bischoff, Rainer;
- Melgert, Barbro N.
Publication type:
Article
Adipose Stromal Cell-Secretome Counteracts Profibrotic Signals From IPF Lung Matrices.
Published in:
Frontiers in Pharmacology, 2021, v. 12, p. 1, doi. 10.3389/fphar.2021.669037
By:
- Vasse, Gwenda F.;
- Van Os, Lisette;
- De Jager, Marina;
- Jonker, Marnix R.;
- Borghuis, Theo;
- Van Den Toorn, L. Tim;
- Jellema, Pytrick;
- White, Eric S.;
- Van Rijn, Patrick;
- Harmsen, Martin C.;
- Heijink, Irene H.;
- Melgert, Barbro N.;
- Burgess, Janette K.
Publication type:
Article
Pregnancy and Preeclampsia Affect Monocyte Subsets in Humans and Rats.
Published in:
PLoS ONE, 2012, v. 7, n. 9, p. 1, doi. 10.1371/journal.pone.0045229
By:
- Melgert, Barbro N.;
- Spaans, Floor;
- Borghuis, Theo;
- Klok, Pieter A.;
- Groen, Bart;
- Bolt, Annemarie;
- de Vos, Paul;
- van Pampus, Maria G.;
- Wong, Tsz Y.;
- van Goor, Harry;
- Bakker, Winston W.;
- Faas, Marijke M.;
- Zenclussen, Ana Claudia
Publication type:
Article
Short-Term Smoke Exposure Attenuates Ovalbumin-Induced Airway Inflammation in Allergic Mice.
Published in:
American Journal of Respiratory Cell & Molecular Biology, 2004, v. 30, n. 6, p. 880, doi. 10.1165/rcmb.2003-0178OC
By:
- Melgert, Barbro N.;
- Postma, Dirkje S.;
- Geerlings, Marie;
- Luinge, Marjan A.;
- Klok, Pieter A.;
- van der Strate, Barry W. A.;
- Kerstjens, Huib A. M.;
- Timens, Wim;
- Hylkema, Machteld N.
Publication type:
Article
Osteoprotegerin is an Early Marker of the Fibrotic Process and of Antifibrotic Treatment Responses in Ex Vivo Lung Fibrosis.
Published in:
Lung, 2024, n. 3, p. 331, doi. 10.1007/s00408-024-00691-5
By:
- Putri, Kurnia S. S.;
- Adhyatmika, Adhyatmika;
- Boorsma, Carian E.;
- Habibie, Habibie;
- Ruigrok, Mitchel J. R.;
- Heukels, Peter;
- Timens, Wim;
- de Jager, Marina H.;
- Hinrichs, Wouter L. J.;
- Olinga, Peter;
- Melgert, Barbro N.
Publication type:
Article
Osteoprotegerin is an Early Marker of the Fibrotic Process and of Antifibrotic Treatment Responses in Ex Vivo Lung Fibrosis.
Published in:
Lung, 2024, v. 202, n. 3, p. 331, doi. 10.1007/s00408-024-00691-5
By:
- Putri, Kurnia S. S.;
- Adhyatmika, Adhyatmika;
- Boorsma, Carian E.;
- Habibie, Habibie;
- Ruigrok, Mitchel J. R.;
- Heukels, Peter;
- Timens, Wim;
- de Jager, Marina H.;
- Hinrichs, Wouter L. J.;
- Olinga, Peter;
- Melgert, Barbro N.
Publication type:
Article
CX Chemokine Receptor 7 Contributes to Survival of KRAS-Mutant Non-Small Cell Lung Cancer upon Loss of Epidermal Growth Factor Receptor.
Published in:
Cancers, 2019, v. 11, n. 4, p. 455, doi. 10.3390/cancers11040455
By:
- Liu, Bin;
- Song, Shanshan;
- Setroikromo, Rita;
- Chen, Siwei;
- Hu, Wenteng;
- Chen, Deng;
- van der Wekken, Anthonie J.;
- Melgert, Barbro N.;
- Timens, Wim;
- van den Berg, Anke;
- Saber, Ali;
- Haisma, Hidde J.
Publication type:
Article
Macrophages: Regulators of Sex Differences in Asthma?
Published in:
American Journal of Respiratory Cell & Molecular Biology, 2010, v. 42, n. 5, p. 595, doi. 10.1165/rcmb.2009-0016OC
By:
- Melgert, Barbro N.;
- Oriss, Timothy B.;
- Zengbiao Qi;
- Dixon-McCarthy, Barbara;
- Geerlings, Marie;
- Hylkema, Machteld N.;
- Ray, Anuradha
Publication type:
Article
The effects of oxygen concentration on cell death, anti-oxidant transcription, acute inflammation, and cell proliferation in precision-cut lung slices.
Published in:
Scientific Reports, 2019, v. 9, n. 1, p. N.PAG, doi. 10.1038/s41598-019-52813-2
By:
- Ruigrok, Mitchel J. R.;
- Tomar, Jasmine;
- Frijlink, Henderik W.;
- Melgert, Barbro N.;
- Hinrichs, Wouter L. J.;
- Olinga, Peter
Publication type:
Article
Time‐Resolved Quantification of Nanoparticle Uptake, Distribution, and Impact in Precision‐Cut Liver Slices.
Published in:
Small, 2020, v. 16, n. 21, p. 1, doi. 10.1002/smll.201906523
By:
- Bartucci, Roberta;
- Åberg, Christoffer;
- Melgert, Barbro N.;
- Boersma, Ykelien L.;
- Olinga, Peter;
- Salvati, Anna
Publication type:
Article
Macrophage migration inhibitory factor family proteins are multitasking cytokines in tissue injury.
Published in:
Cellular & Molecular Life Sciences, 2022, v. 79, n. 2, p. 1, doi. 10.1007/s00018-021-04038-8
By:
- Song, Shanshan;
- Xiao, Zhangping;
- Dekker, Frank J.;
- Poelarends, Gerrit J.;
- Melgert, Barbro N.
Publication type:
Article
Microplastics: A threat for developing and repairing organs?
Published in:
Cambridge Prisms: Plastics, 2023, v. 1, p. 1, doi. 10.1017/plc.2023.19
By:
- Hofstede, Lars T.;
- Vasse, Gwenda F.;
- Melgert, Barbro N.
Publication type:
Article
Modelling Acid-Induced Lung Damage in Precision-Cut Lung Slices: An Ex Vivo Animal Model.
Published in:
Transplantology, 2023, v. 4, n. 4, p. 185, doi. 10.3390/transplantology4040018
By:
- Moes, Carmen A.;
- Gan, C. Tji;
- Venema, Leonie H.;
- Hoffmann, Roland F.;
- Melgert, Barbro N.;
- Kerstjens, Huib A. M.;
- Olinga, Peter;
- Ruigrok, Mitchel J. R.
Publication type:
Article
PvdQ Quorum Quenching Acylase Attenuates Pseudomonas aeruginosa Virulence in a Mouse Model of Pulmonary Infection.
Published in:
Frontiers in Cellular & Infection Microbiology, 2018, v. 8, p. 1, doi. 10.3389/fcimb.2018.00119
By:
- Utari, Putri D.;
- Setroikromo, Rita;
- Melgert, Barbro N.;
- Quax, Wim J.
Publication type:
Article
Proteolysis Targeting Chimera (PROTAC) for Macrophage Migration Inhibitory Factor (MIF) Has Anti‐Proliferative Activity in Lung Cancer Cells.
Published in:
Angewandte Chemie International Edition, 2021, v. 60, n. 32, p. 17514, doi. 10.1002/anie.202101864
By:
- Xiao, Zhangping;
- Song, Shanshan;
- Chen, Deng;
- Merkerk, Ronald;
- Wouden, Petra E.;
- Cool, Robbert H.;
- Quax, Wim J.;
- Poelarends, Gerrit J.;
- Melgert, Barbro N.;
- Dekker, Frank J.
Publication type:
Article
Cigarette Smoke-induced Emphysema.
Published in:
American Journal of Respiratory & Critical Care Medicine, 2006, v. 173, n. 7, p. 751, doi. 10.1164/rccm.200504-594OC
By:
- van der Strate, Barry W. A.;
- Postma, Dirkje S.;
- Brandsma, Corry-Anke;
- Melgert, Barbro N.;
- Luinge, Marjan A.;
- Geerlings, Marie;
- Hylkema, Machteld N.;
- van den Berg, Anke;
- Timens, Wim;
- Kerstjens, Huib A. M.
Publication type:
Article
Single Cell Reactomics: Real‐Time Single‐Cell Activation Kinetics of Optically Trapped Macrophages.
Published in:
Small Methods, 2021, v. 5, n. 4, p. 1, doi. 10.1002/smtd.202000849
By:
- Vasse, Gwenda F.;
- Buzón, Pedro;
- Melgert, Barbro N.;
- Roos, Wouter H.;
- Rijn, Patrick
Publication type:
Article
Genetic regulation of gene expression of MIF family members in lung tissue.
Published in:
Scientific Reports, 2020, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41598-020-74121-w
By:
- Florez-Sampedro, Laura;
- Brandsma, Corry-Anke;
- de Vries, Maaike;
- Timens, Wim;
- Bults, Rene;
- Vermeulen, Cornelis J.;
- van den Berge, Maarten;
- Obeidat, Ma'en;
- Joubert, Philippe;
- Nickle, David C.;
- Poelarends, Gerrit J.;
- Faiz, Alen;
- Melgert, Barbro N.
Publication type:
Article
Effects of lysine deacetylase inhibitor treatment on LPS responses of alveolar-like macrophages.
Published in:
Journal of Leukocyte Biology, 2024, v. 115, n. 3, p. 435, doi. 10.1093/jleuko/qiad121
By:
- Russo, Sara;
- Kwiatkowski, Marcel;
- Wolters, Justina C;
- Gerding, Albert;
- Hermans, Jos;
- Govorukhina, Natalia;
- Bischoff, Rainer;
- Melgert, Barbro N
Publication type:
Article
Macrophage Heterogeneity in Respiratory Diseases.
Published in:
Mediators of Inflammation, 2013, v. 2013, p. 1, doi. 10.1155/2013/769214
By:
- Boorsma, Carian E.;
- Draijer, Christina;
- Melgert, Barbro N.
Publication type:
Article
Characterization of Macrophage Phenotypes in Three Murine Models of House-Dust-Mite-Induced Asthma.
Published in:
Mediators of Inflammation, 2013, v. 2013, p. 1, doi. 10.1155/2013/632049
By:
- Draijer, Christina;
- Robbe, Patricia;
- Boorsma, Carian E.;
- Hylkema, Machteld N.;
- Melgert, Barbro N.
Publication type:
Article
Osteoprotegerin Expression in Liver is Induced by IL13 through TGFβ.
Published in:
Cellular Physiology & Biochemistry (Cell Physiol Biochem Press GmbH & Co. KG), 2022, v. 56, n. 1, p. 28, doi. 10.33594/000000492
By:
- Adhyatmika, Adhyatmika;
- Putri, Kurnia S. S.;
- Gore, Emilia;
- Mangnus, Keri A.;
- Reker-Smit, Catharina;
- Schuppan, Detlef;
- Beljaars, Leonie;
- Olinga, Peter;
- Melgert, Barbro N.
Publication type:
Article
Regulation of Cellular Senescence Is Independent from Profibrotic Fibroblast-Deposited ECM.
Published in:
Cells (2073-4409), 2021, v. 10, n. 7, p. 1628, doi. 10.3390/cells10071628
By:
- Blokland, Kaj E. C.;
- Habibie, Habibie;
- Borghuis, Theo;
- Teitsma, Greta J.;
- Schuliga, Michael;
- Melgert, Barbro N.;
- Knight, Darryl A.;
- Brandsma, Corry-Anke;
- Pouwels, Simon D.;
- Burgess, Janette K.
Publication type:
Article
Enhanced Bruton's tyrosine kinase in B-cells and autoreactive IgA in patients with idiopathic pulmonary fibrosis.
Published in:
2019
By:
- Heukels, Peter;
- van Hulst, Jennifer A. C.;
- van Nimwegen, Menno;
- Boorsma, Carian E.;
- Melgert, Barbro N.;
- von der Thusen, Jan H.;
- van den Blink, Bernt;
- Hoek, Rogier A. S.;
- Miedema, Jelle R.;
- Neys, Stefan F. H.;
- Corneth, Odilia B. J.;
- Hendriks, Rudi W.;
- Wijsenbeek, Marlies S.;
- Kool, Mirjam
Publication type:
journal article
4‐Iodopyrimidine Labeling Reveals Nuclear Translocation and Nuclease Activity for Both MIF and MIF2**.
Published in:
Chemistry - A European Journal, 2022, v. 28, n. 1, p. 1, doi. 10.1002/chem.202103030
By:
- Xiao, Zhangping;
- Chen, Deng;
- Mulder, Fabian;
- Song, Shanshan;
- van der Wouden, Petra E.;
- Cool, Robbert H.;
- Melgert, Barbro N.;
- Poelarends, Gerrit J.;
- Dekker, Frank J.
Publication type:
Article
Extracellular Adenosine Triphosphate Affects Systemic and Kidney Immune Cell Populations in Pregnant Rats.
Published in:
American Journal of Reproductive Immunology, 2014, v. 72, n. 3, p. 305, doi. 10.1111/aji.12267
By:
- Spaans, Floor;
- Melgert, Barbro N.;
- Borghuis, Theo;
- Klok, Pieter A.;
- Vos, Paul;
- Bakker, Winston W.;
- Goor, Harry;
- Faas, Marijke M.
Publication type:
Article
Collagen type XIV is proportionally lower in the lung tissue of patients with IPF.
Published in:
Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-46733-5
By:
- Nizamoglu, Mehmet;
- Koloko Ngassie, Maunick Lefin;
- Meuleman, Rhode A.;
- Banchero, Martin;
- Borghuis, Theo;
- Timens, Wim;
- Nawijn, Martijn C.;
- Melgert, Barbro N.;
- Heijink, Irene H.;
- Brandsma, Corry-Anke;
- Burgess, Janette K.
Publication type:
Article
Hepatic localization of macrophage phenotypes during fibrogenesis and resolution of fibrosis in mice and humans.
Published in:
Frontiers in Immunology, 2014, v. 5, p. 1, doi. 10.3389/fimmu.2014.00430
By:
- Beljaars, Leonie;
- Schippers, Marlies;
- Reker-Smit, Catharina;
- Martinez, Fernando O.;
- Helming, Laura;
- Poelstra, Klaas;
- Melgert, Barbro N.
Publication type:
Article

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