Works by Mele, Luigi

Results: 45

ER stress and/or ER-phagy in drug resistance? Three coincidences are proof.

Published in:

Cell Communication & Signaling, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12964-025-02232-w

By:

Panda, Sameer Kumar;
Sanchez-Pajares, Ibone Rubio;
Rehman, Ayesha;
Del Vecchio, Vitale;
Mele, Luigi;
Chipurupalli, Sandhya;
Robinson, Nirmal;
Desiderio, Vincenzo

Publication type:

Article

Synchrotron Phase Tomography: An Emerging Imaging Method for Microvessel Detection in Engineered Bone of Craniofacial Districts.

Published in:

Frontiers in Physiology, 2017, p. 1, doi. 10.3389/fphys.2017.00769

By:

Giuliani, Alessandra;
Mazzoni, Serena;
Mele, Luigi;
Liccardo, Davide;
Tromba, Giuliana;
Langer, Max

Publication type:

Article

MiR-148a-3p Promotes Colorectal Cancer Cell Ferroptosis by Targeting SLC7A11.

Published in:

Cancers, 2023, v. 15, n. 17, p. 4342, doi. 10.3390/cancers15174342

By:

Martino, Elisa;
Balestrieri, Anna;
Aragona, Francesca;
Bifulco, Giovanna;
Mele, Luigi;
Campanile, Giuseppe;
Balestrieri, Maria Luisa;
D'Onofrio, Nunzia

Publication type:

Article

SIRT3 and Metabolic Reprogramming Mediate the Antiproliferative Effects of Whey in Human Colon Cancer Cells.

Published in:

Cancers, 2021, v. 13, n. 20, p. 5196, doi. 10.3390/cancers13205196

By:

D'Onofrio, Nunzia;
Martino, Elisa;
Balestrieri, Anna;
Mele, Luigi;
Neglia, Gianluca;
Balestrieri, Maria Luisa;
Campanile, Giuseppe

Publication type:

Article

Mi-RNA-888-5p Is Involved in S-Adenosylmethionine Antitumor Effects in Laryngeal Squamous Cancer Cells.

Published in:

Cancers, 2020, v. 12, n. 12, p. 3665, doi. 10.3390/cancers12123665

By:

Pagano, Martina;
Mosca, Laura;
Vitiello, Francesca;
Ilisso, Concetta Paola;
Coppola, Alessandra;
Borzacchiello, Luigi;
Mele, Luigi;
Caruso, Francesca Pia;
Ceccarelli, Michele;
Caraglia, Michele;
Cacciapuoti, Giovanna;
Porcelli, Marina

Publication type:

Article

Synergistic Effect of Dietary Betaines on SIRT1-Mediated Apoptosis in Human Oral Squamous Cell Carcinoma Cal 27.

Published in:

Cancers, 2020, v. 12, n. 9, p. 2468, doi. 10.3390/cancers12092468

By:

D'Onofrio, Nunzia;
Mele, Luigi;
Martino, Elisa;
Salzano, Angela;
Restucci, Brunella;
Cautela, Domenico;
Tatullo, Marco;
Balestrieri, Maria Luisa;
Campanile, Giuseppe

Publication type:

Article

A MEMS-based heating holder for the direct imaging of simultaneous in-situ heating and biasing experiments in scanning/transmission electron microscopes.

Published in:

Microscopy Research & Technique, 2016, v. 79, n. 4, p. 239, doi. 10.1002/jemt.22623

By:

Mele, Luigi;
Konings, Stan;
Dona, Pleun;
Evertz, Francis;
Mitterbauer, Christoph;
Faber, Pybe;
Schampers, Ruud;
Jinschek, Joerg R.

Publication type:

Article

β<sub>2</sub>-AR inhibition enhances EGFR antibody efficacy hampering the oxidative stress response machinery.

Published in:

Cell Death & Disease, 2023, v. 14, n. 9, p. 1, doi. 10.1038/s41419-023-06129-9

By:

Del Vecchio, Vitale;
Mele, Luigi;
Panda, Sameer Kumar;
Sanchez-Pajares, Ibone Rubio;
Mosca, Laura;
Tirino, Virginia;
Barbieri, Massimiliano;
Bruzzese, Francesca;
Luciano, Antonio;
Marino, Federica Zito;
Accardo, Marina;
Nicoletti, Giovanni Francesco;
Papaccio, Gianpaolo;
Barbieri, Antonio;
Desiderio, Vincenzo

Publication type:

Article

A new inhibitor of glucose-6-phosphate dehydrogenase blocks pentose phosphate pathway and suppresses malignant proliferation and metastasis in vivo.

Published in:

Cell Death & Disease, 2018, v. 9, n. 5, p. 1, doi. 10.1038/s41419-018-0635-5

By:

Mele, Luigi;
Paino, Francesca;
Papaccio, Federica;
Regad, Tarik;
Boocock, David;
Stiuso, Paola;
Lombardi, Angela;
Liccardo, Davide;
Aquino, Gabriella;
Barbieri, Antonio;
Arra, Claudio;
Coveney, Clare;
La Noce, Marcella;
Papaccio, Gianpaolo;
Caraglia, Michele;
Tirino, Virginia;
Desiderio, Vincenzo

Publication type:

Article

S-Adenosylmethionine-mediated apoptosis is potentiated by autophagy inhibition induced by chloroquine in human breast cancer cells.

Published in:

Journal of Cellular Physiology, 2018, v. 233, n. 2, p. 1370, doi. 10.1002/jcp.26015

By:

Cave, Donatella Delle;
Desiderio, Vincenzo;
Mosca, Laura;
Ilisso, Concetta P.;
Mele, Luigi;
Caraglia, Michele;
Cacciapuoti, Giovanna;
Porcelli, Marina

Publication type:

Article

Levofolene modulates apoptosis induced by 5-fluorouracil through autophagy inhibition: Clinical and occupational implications.

Published in:

International Journal of Oncology, 2015, v. 46, n. 5, p. 1893, doi. 10.3892/ijo.2015.2904

By:

LAMBERTI, MONICA;
PORTO, STEFANIA;
ZAPPAVIGNA, SILVIA;
STIUSO, PAOLA;
TIRINO, VIRGINIA;
DESIDERIO, VINCENZO;
MELE, LUIGI;
CARAGLIA, MICHELE

Publication type:

Article

The Use of Ground Source Heat Pump to Achieve a Net Zero Energy Building.

Published in:

Energies (19961073), 2020, v. 13, n. 13, p. 3450, doi. 10.3390/en13133450

By:

D'Agostino, Diana;
Mele, Luigi;
Minichiello, Francesco;
Renno, Carlo

Publication type:

Article

Whey Improves In Vitro Endothelial Mitochondrial Function and Metabolic Redox Status in Diabetic State.

Published in:

Antioxidants, 2023, v. 12, n. 6, p. 1311, doi. 10.3390/antiox12061311

By:

Martino, Elisa;
Luce, Amalia;
Balestrieri, Anna;
Mele, Luigi;
Anastasio, Camilla;
D'Onofrio, Nunzia;
Balestrieri, Maria Luisa;
Campanile, Giuseppe

Publication type:

Article

SIRT3 Modulates Endothelial Mitochondrial Redox State during Insulin Resistance.

Published in:

Antioxidants, 2022, v. 11, n. 8, p. N.PAG, doi. 10.3390/antiox11081611

By:

Martino, Elisa;
Balestrieri, Anna;
Anastasio, Camilla;
Maione, Martina;
Mele, Luigi;
Cautela, Domenico;
Campanile, Giuseppe;
Balestrieri, Maria Luisa;
D'Onofrio, Nunzia

Publication type:

Article

Xanthohumol modulate autophagy and ER stress to counteract stemness and enhance cisplatin efficacy in head and neck squamous cell carcinoma.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-98003-1

By:

Del Vecchio, Vitale;
Sanchez-Pajares, Ibone Rubio;
Panda, Sameer Kumar;
Rehman, Ayesha;
De Falco, Vincenzo;
Nigam, Aditya;
Mosca, Laura;
Russo, Diana;
Arena, Claudia;
Nicoletti, Maria Maddalena;
Desiderio, Vincenzo;
Papaccio, Gianpaolo;
Mele, Luigi;
Laino, Luigi

Publication type:

Article

Milk Exosomal miR-27b Worsen Endoplasmic Reticulum Stress Mediated Colorectal Cancer Cell Death.

Published in:

Nutrients, 2022, v. 14, n. 23, p. 5081, doi. 10.3390/nu14235081

By:

Martino, Elisa;
Balestrieri, Anna;
Mele, Luigi;
Sardu, Celestino;
Marfella, Raffaele;
D'Onofrio, Nunzia;
Campanile, Giuseppe;
Balestrieri, Maria Luisa

Publication type:

Article

S-Adenosylmethionine regulates apoptosis and autophagy in MCF-7 breast cancer cells through the modulation of specific microRNAs.

Published in:

Cancer Cell International, 2018, v. 18, n. 1, p. N.PAG, doi. 10.1186/s12935-018-0697-6

By:

Ilisso, Concetta Paola;
Delle Cave, Donatella;
Mosca, Laura;
Pagano, Martina;
Coppola, Alessandra;
Caraglia, Michele;
Cacciapuoti, Giovanna;
Porcelli, Marina;
Mele, Luigi

Publication type:

Article

Annurca apple polyphenol extract selectively kills MDA-MB-231 cells through ROS generation, sustained JNK activation and cell growth and survival inhibition.

Published in:

Scientific Reports, 2019, v. 9, n. 1, p. N.PAG, doi. 10.1038/s41598-019-49631-x

By:

Martino, Elisa;
Vuoso, Daniela Cristina;
D'Angelo, Stefania;
Mele, Luigi;
D'Onofrio, Nunzia;
Porcelli, Marina;
Cacciapuoti, Giovanna

Publication type:

Article

Vulnerability to low-dose combination of irinotecan and niraparib in ATM-mutated colorectal cancer.

Published in:

Journal of Experimental & Clinical Cancer Research (17569966), 2021, v. 40, n. 1, p. 1, doi. 10.1186/s13046-020-01811-8

By:

Vitiello, Pietro Paolo;
Martini, Giulia;
Mele, Luigi;
Giunta, Emilio Francesco;
De Falco, Vincenzo;
Ciardiello, Davide;
Belli, Valentina;
Cardone, Claudia;
Matrone, Nunzia;
Poliero, Luca;
Tirino, Virginia;
Napolitano, Stefania;
Della Corte, Carminia;
Selvaggi, Francesco;
Papaccio, Gianpaolo;
Troiani, Teresa;
Morgillo, Floriana;
Desiderio, Vincenzo;
Ciardiello, Fortunato;
Martinelli, Erika

Publication type:

Article

Olive Oil Phenols Prevent Mercury-Induced Phosphatidylserine Exposure and Morphological Changes in Human Erythrocytes Regardless of Their Different Scavenging Activity.

Published in:

International Journal of Molecular Sciences, 2022, v. 23, n. 10, p. 5693, doi. 10.3390/ijms23105693

By:

Notariale, Rosaria;
Perrone, Pasquale;
Mele, Luigi;
Lettieri, Gennaro;
Piscopo, Marina;
Manna, Caterina

Publication type:

Article

S-Adenosylmethionine Increases the Sensitivity of Human Colorectal Cancer Cells to 5-Fluorouracil by Inhibiting P-Glycoprotein Expression and NF-κB Activation.

Published in:

International Journal of Molecular Sciences, 2021, v. 22, n. 17, p. 9286, doi. 10.3390/ijms22179286

By:

Mosca, Laura;
Pagano, Martina;
Borzacchiello, Luigi;
Mele, Luigi;
Russo, Annapina;
Russo, Giulia;
Cacciapuoti, Giovanna;
Porcelli, Marina

Publication type:

Article

Colorectal Cancer Apoptosis Induced by Dietary δ-Valerobetaine Involves PINK1/Parkin Dependent-Mitophagy and SIRT3.

Published in:

International Journal of Molecular Sciences, 2021, v. 22, n. 15, p. 8117, doi. 10.3390/ijms22158117

By:

D'Onofrio, Nunzia;
Martino, Elisa;
Mele, Luigi;
Colloca, Antonino;
Maione, Martina;
Cautela, Domenico;
Castaldo, Domenico;
Balestrieri, Maria Luisa

Publication type:

Article

S-Adenosyl-l-Methionine Overcomes uL3-Mediated Drug Resistance in p53 Deleted Colon Cancer Cells.

Published in:

International Journal of Molecular Sciences, 2021, v. 22, n. 1, p. 103, doi. 10.3390/ijms22010103

By:

Mosca, Laura;
Pagano, Martina;
Pecoraro, Annalisa;
Borzacchiello, Luigi;
Mele, Luigi;
Cacciapuoti, Giovanna;
Porcelli, Marina;
Russo, Giulia;
Russo, Annapina

Publication type:

Article

Uremic Toxin Lanthionine Interferes with the Transsulfuration Pathway, Angiogenetic Signaling and Increases Intracellular Calcium.

Published in:

International Journal of Molecular Sciences, 2019, v. 20, n. 9, p. 2269, doi. 10.3390/ijms20092269

By:

Vigorito, Carmela;
Anishchenko, Evgeniya;
Mele, Luigi;
Capolongo, Giovanna;
Trepiccione, Francesco;
Zacchia, Miriam;
Lombari, Patrizia;
Capasso, Rosanna;
Ingrosso, Diego;
Perna, Alessandra F.

Publication type:

Article

Morphological and Functional Evaluation of Oral Citicoline Therapy in Chronic Open-Angle Glaucoma Patients: A Pilot Study With a 2-Year Follow-Up.

Published in:

Frontiers in Pharmacology, 2019, p. 1, doi. 10.3389/fphar.2019.01117

By:

Lanza, Michele;
Gironi Carnevale, Ugo Antonello;
Mele, Luigi;
Bifani Sconocchia, Mario;
Bartollino, Silvia;
Costagliola, Ciro

Publication type:

Article

Diet-derived ergothioneine induces necroptosis in colorectal cancer cells by activating the SIRT3/MLKL pathway.

Published in:

FEBS Letters, 2022, v. 596, n. 10, p. 1313, doi. 10.1002/1873-3468.14310

By:

D’Onofrio, Nunzia;
Martino, Elisa;
Balestrieri, Anna;
Mele, Luigi;
Cautela, Domenico;
Castaldo, Domenico;
Luisa Balestrieri, Maria

Publication type:

Article

SGLT2 inhibitor promotes mitochondrial dysfunction and ER-phagy in colorectal cancer cells.

Published in:

Cellular & Molecular Biology Letters, 2024, v. 29, n. 1, p. 1, doi. 10.1186/s11658-024-00599-1

By:

Anastasio, Camilla;
Donisi, Isabella;
Del Vecchio, Vitale;
Colloca, Antonino;
Mele, Luigi;
Sardu, Celestino;
Marfella, Raffaele;
Balestrieri, Maria Luisa;
D'Onofrio, Nunzia

Publication type:

Article

MiR-15b-5p and PCSK9 inhibition reduces lipopolysaccharide-induced endothelial dysfunction by targeting SIRT4.

Published in:

Cellular & Molecular Biology Letters, 2023, v. 28, n. 1, p. 1, doi. 10.1186/s11658-023-00482-5

By:

Martino, Elisa;
D'Onofrio, Nunzia;
Balestrieri, Anna;
Mele, Luigi;
Sardu, Celestino;
Marfella, Raffaele;
Campanile, Giuseppe;
Balestrieri, Maria Luisa

Publication type:

Article

AdoMet triggers apoptosis in head and neck squamous cancer by inducing ER stress and potentiates cell sensitivity to cisplatin.

Published in:

Journal of Cellular Physiology, 2019, v. 234, n. 8, p. 13277, doi. 10.1002/jcp.28000

By:

Mosca, Laura;
Pagano, Martina;
Ilisso, Concetta Paola;
Cave, Donatella Delle;
Desiderio, Vincenzo;
Mele, Luigi;
Caraglia, Michele;
Cacciapuoti, Giovanna;
Porcelli, Marina

Publication type:

Article

Very-High Dynamic Range, 10,000 Frames/Second Pixel Array Detector for Electron Microscopy.

Published in:

Microscopy & Microanalysis, 2022, v. 28, n. 2, p. 425, doi. 10.1017/S1431927622000174

By:

Philipp, Hugh T.;
Tate, Mark W.;
Shanks, Katherine S.;
Mele, Luigi;
Peemen, Maurice;
Dona, Pleun;
Hartong, Reinout;
van Veen, Gerard;
Shao, Yu-Tsun;
Chen, Zhen;
Thom-Levy, Julia;
Muller, David A.;
Gruner, Sol M.

Publication type:

Article

Dose-efficient strain mapping with high precision and throughput using cepstral transforms on 4D-STEM data.

Published in:

2021

By:

Harikrishnan, K. P.;
Yoon, Dasol;
Shao, Yu-Tsun;
Mele, Luigi;
Mitterbauer, Christoph;
Muller, David

Publication type:

Abstract

Wide Dynamic Range, 10 kHz Framing Detector for 4D-STEM.

Published in:

2021

By:

Philipp, Hugh;
Tate, Mark;
Shanks, Katherine;
Mele, Luigi;
Peemen, Maurice;
Dona, Pleun;
Hartong, Reinout;
van Veen, Gerard;
Shao, Yu-Tsun;
Gruner, Sol;
Thom-Levy, Julia;
Muller, David

Publication type:

Abstract

Dose-efficient strain mapping with high precision and throughput using cepstral transforms on 4D-STEM data.

Published in:

2021

By:

Harikrishnan, K. P.;
Yoon, Dasol;
Shao, Yu-Tsun;
Mele, Luigi;
Mitterbauer, Christoph;
Muller, David

Publication type:

Abstract

Wide Dynamic Range, 10 kHz Framing Detector for 4D-STEM.

Published in:

2021

By:

Philipp, Hugh;
Tate, Mark;
Shanks, Katherine;
Mele, Luigi;
Peemen, Maurice;
Dona, Pleun;
Hartong, Reinout;
van Veen, Gerard;
Shao, Yu-Tsun;
Gruner, Sol;
Thom-Levy, Julia;
Muller, David

Publication type:

Abstract

Live Imaging of Reversible Domain Evolution in BaTiO3 on the Nanometer Scale Using in-situ STEM and TEM.

Published in:

Microscopy & Microanalysis, 2014, v. 20, n. S3, p. 1560, doi. 10.1017/S1431927614009532

By:

Schilling, Alina;
Barton, Bastian;
Jinschek, Joerg R.;
Mele, Luigi;
Dona, Pleun;
Ringnalda, Jan;
Arredondo, Miryam;
Einsle, Joshua F.;
Gregg, Marty

Publication type:

Article

Cytoplasmic Interactions between the Glucocorticoid Receptor and HDAC2 Regulate Osteocalcin Expression in VPA-Treated MSCs.

Published in:

Cells (2073-4409), 2019, v. 8, n. 3, p. 217, doi. 10.3390/cells8030217

By:

La Noce, Marcella;
Mele, Luigi;
Laino, Luigi;
Iolascon, Giovanni;
Pieretti, Gorizio;
Papaccio, Gianpaolo;
Desiderio, Vincenzo;
Tirino, Virginia;
Paino, Francesca

Publication type:

Article

Changing Paradigms in Cranio-Facial Regeneration: Current and New Strategies for the Activation of Endogenous Stem Cells.

Published in:

Frontiers in Physiology, 2016, p. 1, doi. 10.3389/fphys.2016.00062

By:

Mele, Luigi;
Vitiello, Pietro Paolo;
Tirino, Virginia;
Paino, Francesca;
De Rosa, Alfredo;
Liccardo, Davide;
Papaccio, Gianpaolo;
Desiderio, Vincenzo

Publication type:

Article

HDAC2 depletion promotes osteosarcoma's stemness both in vitro and in vivo: a study on a putative new target for CSCs directed therapy.

Published in:

Journal of Experimental & Clinical Cancer Research (17569966), 2018, v. 37, n. 1, p. N.PAG, doi. 10.1186/s13046-018-0978-x

By:

La Noce, Marcella;
Mele, Luigi;
Papaccio, Gianpaolo;
Desiderio, Vincenzo;
Tirino, Virginia;
Paino, Francesca;
Regad, Tarik;
Lombardi, Angela;
Papaccio, Federica

Publication type:

Article

Antitumoral Activity of the Universal Methyl Donor S -Adenosylmethionine in Glioblastoma Cells.

Published in:

Molecules, 2024, v. 29, n. 8, p. 1708, doi. 10.3390/molecules29081708

By:

Mosca, Laura;
Pagano, Cristina;
Tranchese, Roberta Veglia;
Grillo, Roberta;
Cadoni, Francesca;
Navarra, Giovanna;
Coppola, Laura;
Pagano, Martina;
Mele, Luigi;
Cacciapuoti, Giovanna;
Laezza, Chiara;
Porcelli, Marina

Publication type:

Article

The Role of 3 Tesla Diffusion-Weighted Imaging in the Differential Diagnosis of Benign versus Malignant Cervical Lymph Nodes in Patients with Head and Neck Squamous Cell Carcinoma.

Published in:

2014

By:

Barchetti, Flavio;
Pranno, Nicola;
Giraldi, Guglielmo;
Sartori, Alessandro;
Gigli, Silvia;
Barchetti, Giovanni;
Lo Mele, Luigi;
Marsella, Luigi Tonino

Publication type:

Journal Article

The Role of 3 Tesla Diffusion-Weighted Imaging in the Differential Diagnosis of Benign versus Malignant Cervical Lymph Nodes in Patients with Head and Neck Squamous Cell Carcinoma.

Published in:

BioMed Research International, 2014, v. 2014, p. 1, doi. 10.1155/2014/532095

By:

Barchetti, Flavio;
Pranno, Nicola;
Giraldi, Guglielmo;
Sartori, Alessandro;
Gigli, Silvia;
Barchetti, Giovanni;
Mele, Luigi Lo;
Marsella, Luigi Tonino

Publication type:

Article

Mitochondrial trafficking in the tumour microenvironment: impact on breast cancer progression and drug resistance.

Published in:

Italian Journal of Anatomy & Embryology / Archivio Italiano di Anatomia Ed Embriologia, 2022, v. 126, p. 135

By:

Tirino, Virginia;
Vecchio, Vitale Del;
Mele, Luigi;
La Noce, Marcella;
Prisco, Claudia;
Panda, Sameer Kumar;
Sanchez Parajes, Ibone Rubio;
De Falco, Vincenzo;
Desiderio, Vincenzo;
Papaccio, Gianpaolo

Publication type:

Article

Midkine is responsible of drug resistance in melanoma patients after treatment with MEK and ERK inhibitors.

Published in:

Italian Journal of Anatomy & Embryology / Archivio Italiano di Anatomia Ed Embriologia, 2021, v. 125, p. 152

By:

Desiderio, Vincenzo;
Sanchez-Rubio, Ibone;
Liccardo, Davide;
Del Vecchio, Vitale;
Prisco, Claudia;
Mele, Luigi;
Panda, Sameer Kumar;
La Noce, Marcella;
Tirino, Virginia;
Papaccio, Gianpaolo

Publication type:

Article

Epigenetic control of gene expression in human mesenchymal stem cells during osteogenic differentiation.

Published in:

2018

By:

La Noce, Marcella;
Mele, Luigi;
Desiderio, Vincenzo;
Tirino, Virginia;
Papaccio, Gianpaolo;
Paino, Francesca

Publication type:

Abstract

Pentose phosphate pathway inhibition induce Endoplasmic Reticulum stress and autophagy.

Published in:

2017

By:

Mele, Luigi;
Paino, Francesca;
Regad, Tarik;
Stiuso, Paola;
Lombardi, Angela;
Liccardo, Davide;
Papaccio, Gianpaolo;
Caraglia, Michele;
Tirino, Virginia;
Desiderio, Vincenzo

Publication type:

Abstract