Works matching AU Melaiu, Ombretta

Results: 33

A genome-wide shRNA screen uncovers a novel potential ligand for NK cell activating receptors.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1537876

By:

Romania, Paolo;
Cifaldi, Loredana;
Gragera, Paula;
D'Alicandro, Valerio;
Caforio, Matteo;
Folgiero, Valentina;
Lucarini, Valeria;
Melaiu, Ombretta;
Bei, Roberto;
Locatelli, Franco;
Fruci, Doriana

Publication type:

Article

Two bullets in the gun: combining immunotherapy with chemotherapy to defeat neuroblastoma by targeting adrenergicmesenchymal plasticity.

Published in:

Frontiers in Immunology, 2023, p. 1, doi. 10.3389/fimmu.2023.1268645

By:

D’Amico, Silvia;
Tempora, Patrizia;
Gragera, Paula;
Król, Kamila;
Melaiu, Ombretta;
De Ioris, Maria Antonietta;
Locatelli, Franco;
Fruci, Doriana

Publication type:

Article

Editorial: Cell network in antitumor immunity of pediatric and adult solid tumors.

Published in:

Frontiers in Immunology, 2023, p. 1, doi. 10.3389/fimmu.2023.1246695

By:

Pesce, Silvia;
Melaiu, Ombretta

Publication type:

Article

DNAM-1 chimeric receptor-engineered NK cells: a new frontier for CAR-NK cell-based immunotherapy.

Published in:

Frontiers in Immunology, 2023, p. 1, doi. 10.3389/fimmu.2023.1197053

By:

Cifaldi, Loredana;
Melaiu, Ombretta;
Giovannoni, Roberto;
Benvenuto, Monica;
Focaccetti, Chiara;
Nardozi, Daniela;
Barillari, Giovanni;
Bei, Roberto

Publication type:

Article

Effects of Angiogenic Factors on the Epithelial-to-Mesenchymal Transition and Their Impact on the Onset and Progression of Oral Squamous Cell Carcinoma: An Overview.

Published in:

Cells (2073-4409), 2024, v. 13, n. 15, p. 1294, doi. 10.3390/cells13151294

By:

Pomella, Silvia;
Melaiu, Ombretta;
Dri, Maria;
Martelli, Mirko;
Gargari, Marco;
Barillari, Giovanni

Publication type:

Article

A methodological reappraisal of total and high molecular weight adiponectin determination in human peripheral circulation: comparison of four immunometric assays.

Published in:

Clinical Chemistry & Laboratory Medicine, 2010, v. 48, n. 4, p. 561, doi. 10.1515/CCLM.2010.104

By:

Caselli, Chiara;
Melaiu, Ombretta;
Maltinti, Maristella;
Del Ry, Silvia;
Cabiati, Manuela;
Prescimone, Tommaso;
Neglia, Danilo;
Giannessi, Daniela

Publication type:

Article

Combined mitoxantrone and anti-TGFβ treatment with PD-1 blockade enhances antitumor immunity by remodelling the tumor immune landscape in neuroblastoma.

Published in:

Journal of Experimental & Clinical Cancer Research (17569966), 2022, v. 41, n. 1, p. 1, doi. 10.1186/s13046-022-02525-9

By:

Lucarini, Valeria;
Melaiu, Ombretta;
D'Amico, Silvia;
Pastorino, Fabio;
Tempora, Patrizia;
Scarsella, Marco;
Pezzullo, Marco;
De Ninno, Adele;
D'Oria, Valentina;
Cilli, Michele;
Emionite, Laura;
Infante, Paola;
Di Marcotullio, Lucia;
De Ioris, Maria Antonietta;
Barillari, Giovanni;
Alaggio, Rita;
Businaro, Luca;
Ponzoni, Mirco;
Locatelli, Franco;
Fruci, Doriana

Publication type:

Article

Biomarkers Identification in the Microenvironment of Oral Squamous Cell Carcinoma: A Systematic Review of Proteomic Studies.

Published in:

International Journal of Molecular Sciences, 2024, v. 25, n. 16, p. 8929, doi. 10.3390/ijms25168929

By:

Pomella, Silvia;
Melaiu, Ombretta;
Cifaldi, Loredana;
Bei, Roberto;
Gargari, Marco;
Campanella, Vincenzo;
Barillari, Giovanni

Publication type:

Article

The Combination of Bioavailable Concentrations of Curcumin and Resveratrol Shapes Immune Responses While Retaining the Ability to Reduce Cancer Cell Survival.

Published in:

International Journal of Molecular Sciences, 2024, v. 25, n. 1, p. 232, doi. 10.3390/ijms25010232

By:

Focaccetti, Chiara;
Palumbo, Camilla;
Benvenuto, Monica;
Carrano, Raffaele;
Melaiu, Ombretta;
Nardozi, Daniela;
Angiolini, Valentina;
Lucarini, Valeria;
Kërpi, Bora;
Masuelli, Laura;
Cifaldi, Loredana;
Bei, Roberto

Publication type:

Article

The Combination of Immune Checkpoint Blockade with Tumor Vessel Normalization as a Promising Therapeutic Strategy for Breast Cancer: An Overview of Preclinical and Clinical Studies.

Published in:

2023

By:

Melaiu, Ombretta;
Vanni, Gianluca;
Portarena, Ilaria;
Pistolese, Chiara Adriana;
Anemona, Lucia;
Pomella, Silvia;
Bei, Roberto;
Buonomo, Oreste Claudio;
Roselli, Mario;
Mauriello, Alessandro;
Barillari, Giovanni

Publication type:

Literature Review

DNA Damage Response Gene Signature as Potential Treatment Markers for Oral Squamous Cell Carcinoma.

Published in:

International Journal of Molecular Sciences, 2023, v. 24, n. 3, p. 2673, doi. 10.3390/ijms24032673

By:

Pomella, Silvia;
Cassandri, Matteo;
Melaiu, Ombretta;
Marampon, Francesco;
Gargari, Marco;
Campanella, Vincenzo;
Rota, Rossella;
Barillari, Giovanni

Publication type:

Article

The Multiple Roles of CD147 in the Development and Progression of Oral Squamous Cell Carcinoma: An Overview.

Published in:

International Journal of Molecular Sciences, 2022, v. 23, n. 15, p. 8336, doi. 10.3390/ijms23158336

By:

Barillari, Giovanni;
Melaiu, Ombretta;
Gargari, Marco;
Pomella, Silvia;
Bei, Roberto;
Campanella, Vincenzo

Publication type:

Article

Quantification of the Immune Content in Neuroblastoma: Deep Learning and Topological Data Analysis in Digital Pathology.

Published in:

International Journal of Molecular Sciences, 2021, v. 22, n. 16, p. 8804, doi. 10.3390/ijms22168804

By:

Bussola, Nicole;
Papa, Bruno;
Melaiu, Ombretta;
Castellano, Aurora;
Fruci, Doriana;
Jurman, Giuseppe

Publication type:

Article

Identification of Overexpressed Genes in Malignant Pleural Mesothelioma.

Published in:

International Journal of Molecular Sciences, 2021, v. 22, n. 5, p. 2738, doi. 10.3390/ijms22052738

By:

Morani, Federica;
Bisceglia, Luisa;
Rosini, Giulia;
Mutti, Luciano;
Melaiu, Ombretta;
Landi, Stefano;
Gemignani, Federica;
Piaggio, Giulia

Publication type:

Article

ERAP1 and ERAP2 Enzymes: A Protective Shield for RAS against COVID-19?

Published in:

International Journal of Molecular Sciences, 2021, v. 22, n. 4, p. 1705, doi. 10.3390/ijms22041705

By:

D'Amico, Silvia;
Tempora, Patrizia;
Lucarini, Valeria;
Melaiu, Ombretta;
Gaspari, Stefania;
Algeri, Mattia;
Fruci, Doriana;
Filipeanu, Catalin

Publication type:

Article

Impact of Natural Occurring ERAP1 Single Nucleotide Polymorphisms within miRNA-Binding Sites on HCMV Infection.

Published in:

International Journal of Molecular Sciences, 2020, v. 21, n. 16, p. 5861, doi. 10.3390/ijms21165861

By:

Melaiu, Ombretta;
D'Amico, Silvia;
Tempora, Patrizia;
Lucarini, Valeria;
Fruci, Doriana

Publication type:

Article

EIF4G1 and RAN as Possible Drivers for Malignant Pleural Mesothelioma.

Published in:

International Journal of Molecular Sciences, 2020, v. 21, n. 14, p. 4856, doi. 10.3390/ijms21144856

By:

Dell'Anno, Irene;
Barbarino, Marcella;
Barone, Elisa;
Giordano, Antonio;
Luzzi, Luca;
Bottaro, Maria;
Migliore, Loredana;
Agostini, Silvia;
Melani, Alessandra;
Melaiu, Ombretta;
Catalano, Calogerina;
Cipollini, Monica;
Silvestri, Roberto;
Corrado, Alda;
Gemignani, Federica;
Landi, Stefano

Publication type:

Article

Tumor-infiltrating T cells and PD-L1 expression in childhood malignant extracranial germ-cell tumors.

Published in:

OncoImmunology, 2019, v. 8, n. 2, p. 1, doi. 10.1080/2162402X.2018.1542245

By:

Boldrini, Renata;
De Pasquale, Maria Debora;
Melaiu, Ombretta;
Chierici, Marco;
Jurman, Giuseppe;
Benedetti, Maria Chiara;
Salfi, Nunzio C.;
Castellano, Aurora;
Collini, Paola;
Furlanello, Cesare;
Pistoia, Vito;
Cifaldi, Loredana;
Terenziani, Monica;
Fruci, Doriana

Publication type:

Article

MYCN is an immunosuppressive oncogene dampening the expression of ligands for NK-cell-activating receptors in human high-risk neuroblastoma.

Published in:

OncoImmunology, 2017, v. 6, n. 6, p. N.PAG, doi. 10.1080/2162402X.2017.1316439

By:

Brandetti, Elisa;
Veneziani, Irene;
Melaiu, Ombretta;
Pezzolo, Annalisa;
Castellano, Aurora;
Boldrini, Renata;
Ferretti, Elisa;
Fruci, Doriana;
Moretta, Lorenzo;
Pistoia, Vito;
Locatelli, Franco;
Cifaldi, Loredana

Publication type:

Article

Correction: MSLN gene silencing has an anti-malignant effect on cell lines overexpressing mesothelin deriving from malignant pleural mesothelioma.

Published in:

2017

By:

Melaiu, Ombretta;
Stebbing, Justin;
Lombardo, Ylenia;
Bracci, Elisa;
Uehara, Norihisa;
Bonotti, Alessandra;
Cristaudo, Alfonso;
Foddis, Rudy;
Mutti, Luciano;
Barale, Roberto;
Gemignani, Federica;
Giamas, Georgios;
Landi, Stefano

Publication type:

Correction Notice

Dendritic Cells: Behind the Scenes of T-Cell Infiltration into the Tumor Microenvironment.

Published in:

Cancers, 2021, v. 13, n. 3, p. 433, doi. 10.3390/cancers13030433

By:

Lucarini, Valeria;
Melaiu, Ombretta;
Tempora, Patrizia;
D'Amico, Silvia;
Locatelli, Franco;
Fruci, Doriana

Publication type:

Article

Combining ERAP1 silencing and entinostat therapy to overcome resistance to cancer immunotherapy in neuroblastoma.

Published in:

Journal of Experimental & Clinical Cancer Research (17569966), 2024, v. 43, n. 1, p. 1, doi. 10.1186/s13046-024-03180-y

By:

Tempora, Patrizia;
D'Amico, Silvia;
Gragera, Paula;
Damiani, Verena;
Krol, Kamila;
Scaldaferri, Valentina;
Pandey, Kirti;
Chung, Shanzou;
Lucarini, Valeria;
Giorda, Ezio;
Scarsella, Marco;
Volpe, Gabriele;
Pezzullo, Marco;
De Stefanis, Cristiano;
D'Oria, Valentina;
De Angelis, Lorenzo;
Giovannoni, Roberto;
De Ioris, Maria Antonietta;
Melaiu, Ombretta;
Purcell, Anthony W.

Publication type:

Article

Drug-repositioning screening identified fludarabine and risedronic acid as potential therapeutic compounds for malignant pleural mesothelioma.

Published in:

Investigational New Drugs, 2021, v. 39, n. 3, p. 644, doi. 10.1007/s10637-020-01040-y

By:

Dell'Anno, Irene;
Martin, Sarah A.;
Barbarino, Marcella;
Melani, Alessandra;
Silvestri, Roberto;
Bottaro, Maria;
Paolicchi, Elisa;
Corrado, Alda;
Cipollini, Monica;
Melaiu, Ombretta;
Giordano, Antonio;
Luzzi, Luca;
Gemignani, Federica;
Landi, Stefano

Publication type:

Article

Association between CYP2E1 polymorphisms and risk of differentiated thyroid carcinoma.

Published in:

Archives of Toxicology, 2016, v. 90, n. 12, p. 3099, doi. 10.1007/s00204-016-1660-8

By:

Pellé, Lucia;
Cipollini, Monica;
Tremmel, Roman;
Romei, Cristina;
Figlioli, Gisella;
Gemignani, Federica;
Melaiu, Ombretta;
Santi, Chiara;
Barone, Elisa;
Elisei, Rossella;
Seiser, Eric;
Innocenti, Federico;
Zanger, Ulrich;
Landi, Stefano

Publication type:

Article

Polymorphisms Within the RET Proto-Oncogene and Risk of Sporadic Medullary Thyroid Carcinoma.

Published in:

Thyroid, 2020, v. 30, n. 11, p. 1579, doi. 10.1089/thy.2019.0352

By:

Gemignani, Federica;
Romei, Cristina;
Ciampi, Raffaele;
Corrado, Alda;
Melaiu, Ombretta;
Figlioli, Gisella;
Bonotti, Alessandra;
Foddis, Rudy;
Cristaudo, Alfonso;
Pellegrini, Giovanni;
Vivaldi, Agnese;
Cipollini, Monica;
Landi, Stefano;
Elisei, Rossella

Publication type:

Article

Common gene variants within 3′‐untranslated regions as modulators of multiple myeloma risk and survival.

Published in:

International Journal of Cancer, 2021, v. 148, n. 8, p. 1887, doi. 10.1002/ijc.33377

By:

Melaiu, Ombretta;
Macauda, Angelica;
Sainz, Juan;
Calvetti, Diego;
Facioni, Maria Sole;
Maccari, Giuseppe;
Horst, Rob;
Netea, Mihai G.;
Li, Yang;
Grząśko, Norbert;
Moreno, Victor;
Jurczyszyn, Artur;
Jerez, Andrés;
Watek, Marzena;
Varkonyi, Judit;
Garcia‐Sanz, Ramon;
Kruszewski, Marcin;
Dudziński, Marek;
Kadar, Katalin;
Jacobsen, Svend Erik Hove

Publication type:

Article

Genetically driven CD39 expression shapes human tumor‐infiltrating CD8<sup>+</sup> T‐cell functions.

Published in:

International Journal of Cancer, 2020, v. 147, n. 9, p. 2597, doi. 10.1002/ijc.33131

By:

Gallerano, Daniela;
Ciminati, Selina;
Grimaldi, Alessio;
Piconese, Silvia;
Cammarata, Ilenia;
Focaccetti, Chiara;
Pacella, Ilenia;
Accapezzato, Daniele;
Lancellotti, Francesco;
Sacco, Luca;
Caronna, Roberto;
Melaiu, Ombretta;
Fruci, Doriana;
D'Oria, Valentina;
Manzi, Emy;
Sagnotta, Andrea;
Parrino, Chiara;
Coletta, Diego;
Peruzzi, Giovanna;
Terenzi, Valentina

Publication type:

Article

Cellular and gene signatures of tumor-infiltrating dendritic cells and natural-killer cells predict prognosis of neuroblastoma.

Published in:

Nature Communications, 2020, v. 11, n. 1, p. N.PAG, doi. 10.1038/s41467-020-19781-y

By:

Melaiu, Ombretta;
Chierici, Marco;
Lucarini, Valeria;
Jurman, Giuseppe;
Conti, Libenzio Adrian;
De Vito, Rita;
Boldrini, Renata;
Cifaldi, Loredana;
Castellano, Aurora;
Furlanello, Cesare;
Barnaba, Vincenzo;
Locatelli, Franco;
Fruci, Doriana

Publication type:

Article

<i>MSLN</i> Gene Silencing Has an Anti-Malignant Effect on Cell Lines Overexpressing Mesothelin Deriving from Malignant Pleural Mesothelioma.

Published in:

PLoS ONE, 2014, v. 9, n. 1, p. 1, doi. 10.1371/journal.pone.0085935

By:

Melaiu, Ombretta;
Stebbing, Justin;
Lombardo, Ylenia;
Bracci, Elisa;
Uehara, Norihisa;
Bonotti, Alessandra;
Cristaudo, Alfonso;
Foddis, Rudy;
Mutti, Luciano;
Barale, Roberto;
Gemignani, Federica;
Giamas, Georgios;
Landi, Stefano

Publication type:

Article

Immunogenic Cell Death Inducers in Cancer Immunotherapy to Turn Cold Tumors into Hot Tumors.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 4, p. 1613, doi. 10.3390/ijms26041613

By:

Lucarini, Valeria;
Melaiu, Ombretta;
Gragera, Paula;
Król, Kamila;
Scaldaferri, Valentina;
Damiani, Verena;
De Ninno, Adele;
Nardozi, Daniela;
Businaro, Luca;
Masuelli, Laura;
Bei, Roberto;
Cifaldi, Loredana;
Fruci, Doriana

Publication type:

Article

Targeting the antigen processing and presentation pathway to overcome resistance to immune checkpoint therapy.

Published in:

Frontiers in Immunology, 2022, v. 13, p. 1, doi. 10.3389/fimmu.2022.948297

By:

D'Amico, Silvia;
Tempora, Patrizia;
Melaiu, Ombretta;
Lucarini, Valeria;
Cifaldi, Loredana;
Locatelli, Franco;
Fruci, Doriana

Publication type:

Article

ERAP1 Controls the Interaction of the Inhibitory Receptor KIR3DL1 With HLA-B51:01 by Affecting Natural Killer Cell Function.

Published in:

Frontiers in Immunology, 2021, v. 12, p. 1, doi. 10.3389/fimmu.2021.778103

By:

D'Amico, Silvia;
D'Alicandro, Valerio;
Compagnone, Mirco;
Tempora, Patrizia;
Guida, Giusy;
Romania, Paolo;
Lucarini, Valeria;
Melaiu, Ombretta;
Falco, Michela;
Algeri, Mattia;
Pende, Daniela;
Cifaldi, Loredana;
Fruci, Doriana

Publication type:

Article

ERAP1 promotes Hedgehog-dependent tumorigenesis by controlling USP47-mediated degradation of βTrCP.

Published in:

Nature Communications, 2019, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41467-019-11093-0

By:

Bufalieri, Francesca;
Infante, Paola;
Bernardi, Flavia;
Caimano, Miriam;
Romania, Paolo;
Moretti, Marta;
Lospinoso Severini, Ludovica;
Talbot, Julie;
Melaiu, Ombretta;
Tanori, Mirella;
Di Magno, Laura;
Bellavia, Diana;
Capalbo, Carlo;
Puget, Stéphanie;
De Smaele, Enrico;
Canettieri, Gianluca;
Guardavaccaro, Daniele;
Busino, Luca;
Peschiaroli, Angelo;
Pazzaglia, Simonetta

Publication type:

Article