Found: 19
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Widespread brain distribution and activity following i.c.v. infusion of anti-β-secretase (BACE1) in nonhuman primates.
- Published in:
- 2017
- By:
- Publication type:
- journal article
Polarized microtubule remodeling transforms the morphology of reactive microglia and drives cytokine release.
- Published in:
- Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-41891-6
- By:
- Publication type:
- Article
Neprilysin Overexpression Inhibits Plaque Formation But Fails to Reduce Pathogenic Aβ Oligomers and Associated Cognitive Deficits in Human Amyloid Precursor Protein Transgenic Mice.
- Published in:
- Journal of Neuroscience, 2009, v. 29, n. 7, p. 1977, doi. 10.1523/JNEUROSCI.2984-08.2009
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- Publication type:
- Article
Enkephalin Elevations Contribute to Neuronal and Behavioral Impairments in a Transgenic Mouse Model of Alzheimer's Disease.
- Published in:
- Journal of Neuroscience, 2008, v. 28, n. 19, p. 5007, doi. 10.1523/JNEUROSCI.0590-08.2008
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- Publication type:
- Article
Loss of dual leucine zipper kinase signaling is protective in animal models of neurodegenerative disease.
- Published in:
- Science Translational Medicine, 2017, v. 9, n. 403, p. 1, doi. 10.1126/scitranslmed.aag0394
- By:
- Publication type:
- Article
GluN2B Antagonism Affects Interneurons and Leads to Immediate and Persistent Changes in Synaptic Plasticity, Oscillations, and Behavior.
- Published in:
- Neuropsychopharmacology, 2013, v. 38, n. 7, p. 1221, doi. 10.1038/npp.2013.19
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- Publication type:
- Article
Chronic GluN2B Antagonism Disrupts Behavior in Wild- Type Mice Without Protecting Against Synapse Loss or Memory Impairment in Alzheimer's Disease Mouse Models.
- Published in:
- Journal of Neuroscience, 2014, v. 34, n. 24, p. 8277, doi. 10.1523/JNEUROSCI.5106-13.2014
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- Publication type:
- Article
A Death Receptor 6-Amyloid Precursor Protein Pathway Regulates Synapse Density in the Mature CNS But Does Not Contribute to Alzheimer's Disease-Related Pathophysiology in Murine Models.
- Published in:
- Journal of Neuroscience, 2014, v. 34, n. 19, p. 6425, doi. 10.1523/JNEUROSCI.4963-13.2014
- By:
- Publication type:
- Article
P1-062: Tau reduction prevents epileptiform activity in a mouse model of Alzheimer's disease: Gene expression microarray analysis
- Published in:
- 2008
- By:
- Publication type:
- Abstract
P4-314: Overexpression of neprilysin decreases neuronal and behavioral impairments in human amyloid precursor protein transgenic mice
- Published in:
- 2006
- By:
- Publication type:
- Abstract
P4-314: Overexpression of neprilysin decreases neuronal and behavioral impairments in human amyloid precursor protein transgenic mice
- Published in:
- 2006
- By:
- Publication type:
- Abstract
BACE1 across species: a comparison of the in vivo consequences of BACE1 deletion in mice and rats.
- Published in:
- Scientific Reports, 2017, p. 44249, doi. 10.1038/srep44249
- By:
- Publication type:
- Article
Therapeutic bispecific antibodies cross the blood-brain barrier in nonhuman primates.
- Published in:
- Science Translational Medicine, 2014, v. 6, n. 261, p. 1, doi. 10.1126/scitranslmed.3009835
- By:
- Publication type:
- Article
Addressing Safety Liabilities of TfR Bispecific Antibodies That Cross the Blood-Brain Barrier.
- Published in:
- Science Translational Medicine, 2013, v. 5, n. 183, p. 1, doi. 10.1126/scitranslmed.3005338
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- Publication type:
- Article
A Therapeutic Antibody Targeting BACE1 Inhibits Amyloid-β Production in Vivo.
- Published in:
- Science Translational Medicine, 2011, v. 3, n. 84, p. 1, doi. 10.1126/scitranslmed.3002254
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- Publication type:
- Article
Trem2 Deletion Reduces Late-Stage Amyloid Plaque Accumulation, Elevates the Aβ42:Aβ40 Ratio, and Exacerbates Axonal Dystrophy and Dendritic Spine Loss in the PS2APP Alzheimer's Mouse Model.
- Published in:
- Journal of Neuroscience, 2020, v. 40, n. 9, p. 1956, doi. 10.1523/jneurosci.1871-19.2019
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- Publication type:
- Article
Inducible EphA4 knockout causes motor deficits in young mice and is not protective in the SOD1<sup>G93A</sup> mouse model of ALS.
- Published in:
- Scientific Reports, 2020, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41598-020-72723-y
- By:
- Publication type:
- Article
Role of Hippocampal CA3 µ-Opioid Receptors in Spatial Learning and Memory.
- Published in:
- Journal of Neuroscience, 2004, v. 24, n. 12, p. 2953, doi. 10.1523/JNEUROSCI.5569-03.2004
- By:
- Publication type:
- Article
Translational Approaches for Brain Delivery of Biologics via Cerebrospinal Fluid.
- Published in:
- Clinical Pharmacology & Therapeutics, 2022, v. 111, n. 4, p. 826, doi. 10.1002/cpt.2531
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- Publication type:
- Article