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Alzheimer's disease as a synaptopathy: Evidence for dysfunction of synapses during disease progression.
Published in:
Frontiers in Synaptic Neuroscience, 2023, v. 15, p. 1, doi. 10.3389/fnsyn.2023.1129036
By:
- Meftah, Soraya;
- Jian Gan
Publication type:
Article
Impaired glymphatic function and clearance of tau in an Alzheimer's disease model.
Published in:
2020
By:
- Harrison, Ian F;
- Ismail, Ozama;
- Machhada, Asif;
- Colgan, Niall;
- Ohene, Yolanda;
- Nahavandi, Payam;
- Ahmed, Zeshan;
- Fisher, Alice;
- Meftah, Soraya;
- Murray, Tracey K;
- Ottersen, Ole P;
- Nagelhus, Erlend A;
- O'Neill, Michael J;
- Wells, Jack A;
- Lythgoe, Mark F
Publication type:
journal article
Identifying early markers of synaptic dysfunction in a mouse model of tauopathy: Molecular and cell biology/synaptic disruption.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.040342
By:
- Meftah, Soraya;
- Witton, Jonathan;
- Cavallini, Annalisa;
- Murray, Tracey K.;
- Jankowski, Lukasz;
- Bose, Suchira;
- Ashby, Michael;
- Brown, Jonathan T.
Publication type:
Article
Tracking progressive pathological and functional decline in the rTg4510 mouse model of tauopathy.
Published in:
Alzheimer's Research & Therapy, 2017, v. 9, p. 1, doi. 10.1186/s13195-017-0306-2
By:
- Blackmore, Thomas;
- Meftah, Soraya;
- Murray, Tracey Karen;
- Craig, Peter James;
- Blockeel, Anthony;
- Phillips, Keith;
- Eastwood, Brian;
- O'Neill, Michael J.;
- Hugh Marston;
- Ahmed, Zeshan;
- Gilmour, Gary;
- Gastambide, Francois
Publication type:
Article
IN VIVO TWO-PHOTON IMAGING OF THE EFFECTS OF TAUOPATHY AND AMYLOIDOPATHY ON SYNAPSES.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2017, v. 13, p. P1002, doi. 10.1016/j.jalz.2017.06.1390
By:
- Jackson, Johanna;
- Tamagnini, Francesco;
- Johnson, James;
- Stephen, Terri-Leigh;
- Ahmed, Zeshan;
- Oliver-Evans, Alice;
- Meftah, Soraya;
- Hutton, Michael L.;
- Isaac, John;
- Randall, Andrew;
- Ashby, Michael;
- O'Neill, Michael J.
Publication type:
Article
DEVELOPING IN VIVO MODELS OF TAU PROPAGATION WHICH ARE RELEVANT TO HUMAN DISEASE PATHOGENESIS AND APPLICABLE TO PRE-CLINICAL DRUG DISCOVERY.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2017, v. 13, p. P906, doi. 10.1016/j.jalz.2017.07.321
By:
- Ahmed, Zeshan;
- Cooper, Jane;
- Kerridge, Caroline;
- Vargova, Tereza;
- Fisher, Alice;
- Murray, Tracey K.;
- Ward, Mark;
- Meftah, Soraya;
- Cavallini, Annalisa;
- Goedert, Michel;
- Hutton, Michael L.;
- Bose, Suchira;
- O'Neill, Michael J.
Publication type:
Article
IN VIVO TWO-PHOTON IMAGING OF THE EFFECTS OF TAUOPATHY AND AMYLOIDOPATHY ON SYNAPSE DYNAMICS IN THE RTG4510 AND J20 TRANSGENIC MODELS, RESPECTIVELY.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2016, v. 12, p. P1043, doi. 10.1016/j.jalz.2016.06.2168
By:
- Jackson, Johanna;
- Tamagnini, Francesco;
- Johnson, James;
- Ahmed, Zeshan;
- Oliver-Evans, Alice;
- Meftah, Soraya;
- Hutton, Michael;
- Isaac, John;
- Randall, Andrew;
- Ashby, Michael;
- O'Neill, Michael J.
Publication type:
Article
Synaptic alterations associated with disrupted sensory encoding in a mouse model of tauopathy.
Published in:
Brain Communications, 2024, v. 6, n. 3, p. 1, doi. 10.1093/braincomms/fcae134
By:
- Meftah, Soraya;
- Cavallini, Annalisa;
- Murray, Tracey K;
- Jankowski, Lukasz;
- Bose, Suchira;
- Ashby, Michael C;
- Brown, Jonathan T;
- Witton, Jonathan
Publication type:
Article
Transmembrane protein 97 is a potential synaptic amyloid beta receptor in human Alzheimer’s disease.
Published in:
Acta Neuropathologica, 2024, v. 147, n. 1, p. 1, doi. 10.1007/s00401-023-02679-6
By:
- Colom-Cadena, Martí;
- Toombs, Jamie;
- Simzer, Elizabeth;
- Holt, Kristjan;
- McGeachan, Robert;
- Tulloch, Jane;
- Jackson, Rosemary J.;
- Catterson, James H.;
- Spires-Jones, Maxwell P.;
- Rose, Jamie;
- Waybright, Lora;
- Caggiano, Anthony O.;
- King, Declan;
- Gobbo, Francesco;
- Davies, Caitlin;
- Hooley, Monique;
- Dunnett, Sophie;
- Tempelaar, Robert;
- Meftah, Soraya;
- Tzioras, Makis
Publication type:
Article
p-tau Ser356 is associated with Alzheimer’s disease pathology and is lowered in brain slice cultures using the NUAK inhibitor WZ4003.
Published in:
Acta Neuropathologica, 2024, v. 147, n. 1, p. 1, doi. 10.1007/s00401-023-02667-w
By:
- Taylor, Lewis W.;
- Simzer, Elizabeth M.;
- Pimblett, Claire;
- Lacey-Solymar, Oscar T. T.;
- McGeachan, Robert I.;
- Meftah, Soraya;
- Rose, Jamie L.;
- Spires-Jones, Maxwell P.;
- Holt, Kristján;
- Catterson, James H.;
- Koch, Henner;
- Liaquat, Imran;
- Clarke, Jonathan H.;
- Skidmore, John;
- Smith, Colin;
- Booker, Sam A.;
- Brennan, Paul M.;
- Spires-Jones, Tara L.;
- Durrant, Claire S.
Publication type:
Article
A nose for tau.
Published in:
Science Translational Medicine, 2024, v. 16, n. 754, p. 1, doi. 10.1126/scitranslmed.adq6489
By:
- Meftah, Soraya;
- Durrant, Claire S.;
- Spires-Jones, Tara L.
Publication type:
Article

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