Works matching AU Meeker, Alan K.

Results: 44

ATRX loss induces multiple hallmarks of the alternative lengthening of telomeres (ALT) phenotype in human glioma cell lines in a cell line-specific manner.

Published in:

PLoS ONE, 2018, v. 13, n. 9, p. 1, doi. 10.1371/journal.pone.0204159

By:

Brosnan-Cashman, Jacqueline A.;
Yuan, Ming;
Graham, Mindy K.;
Rizzo, Anthony J.;
Myers, Kaylar M.;
Davis, Christine;
Zhang, Rebecca;
Esopi, David M.;
Raabe, Eric H.;
Eberhart, Charles G.;
Heaphy, Christopher M.;
Meeker, Alan K.

Publication type:

Article

A unique telomere DNA expansion phenotype in human retinal rod photoreceptors associated with aging and disease.

Published in:

Brain Pathology, 2019, v. 29, n. 1, p. 45, doi. 10.1111/bpa.12618

By:

Bell, W. Robert;
Meeker, Alan K.;
Rizzo, Anthony;
Rajpara, Sumit;
Rosenthal, Ian M.;
Flores Bellver, Miguel;
Aparicio Domingo, Silvia;
Zhong, Xiufeng;
Barber, John R.;
Joshu, Corinne E.;
Canto‐Soler, M. Valeria;
Eberhart, Charles G.;
Heaphy, Christopher M.

Publication type:

Article

Molecular and Morphologic Correlates of the Alternative Lengthening of Telomeres Phenotype in High-Grade Astrocytomas.

Published in:

Brain Pathology, 2013, v. 23, n. 3, p. 237, doi. 10.1111/j.1750-3639.2012.00630.x

By:

Nguyen, Doreen N.;
Heaphy, Christopher M.;
Wilde, Roeland F.;
Orr, Brent A.;
Odia, Yazmin;
Eberhart, Charles G.;
Meeker, Alan K.;
Rodriguez, Fausto J.

Publication type:

Article

Androgen-induced TOP2B-mediated double-strand breaks and prostate cancer gene rearrangements.

Published in:

Nature Genetics, 2010, v. 42, n. 8, p. 668, doi. 10.1038/ng.613

By:

Haffner, Michael C.;
Aryee, Martin J.;
Toubaji, Antoun;
Esopi, David M.;
Albadine, Roula;
Gurel, Bora;
Isaacs, William B.;
Bova, G. Steven;
Wennuan Liu;
Jianfeng Xu;
Meeker, Alan K.;
Netto, George;
De Marzo, Angelo M.;
Nelson, William G.;
Yegnasubramanian, Srinivasan

Publication type:

Article

Telomere length variation in biliary tract metaplasia, dysplasia, and carcinoma.

Published in:

Modern Pathology, 2006, v. 19, n. 6, p. 772, doi. 10.1038/modpathol.3800591

By:

Hansel, Donna E.;
Meeker, Alan K.;
Hicks, Jessica;
De Marzo, Angelo M.;
Lillemoe, Keith D.;
Schulick, Richard;
Hruban, Ralph H.;
Maitra, Anirban;
Argani, Pedram

Publication type:

Article

Telomere length variation in normal epithelial cells adjacent to tumor: potential biomarker for breast cancer local recurrence.

Published in:

Carcinogenesis, 2012, v. 33, n. 1, p. 113, doi. 10.1093/carcin/bgr248

By:

Zhou, Xin;
Meeker, Alan K.;
Makambi, Kepher H.;
Kosti, Ourania;
Kallakury, Bhaskar V.S.;
Sidawy, Mary K.;
Loffredo, Christopher A.;
Zheng, Yun-Ling

Publication type:

Article

Differentiating Alternative Splice Variant Patterns of Human Telomerase Reverse Transcriptase in Thyroid Neoplasms.

Published in:

Thyroid, 2008, v. 18, n. 10, p. 1055, doi. 10.1089/thy.2008.0101

By:

Yongchun Wang;
Jeanne Kowalski;
Hua-Ling Tsai;
Radharani Marik;
Nijaguna Prasad;
Helina Somervell;
Pang-Kuo Lo;
Lauren E. Sangenario;
Lars Dyrskjot;
Torben F. Orntoft;
William H. Westra;
Alan K. Meeker;
James R. Eshleman;
Christopher B. Umbricht;
Martha A. Zeiger

Publication type:

Article

Telomerase Variant A279T Induces Telomere Dysfunction and Inhibits Non-Canonical Telomerase Activity in Esophageal Carcinomas.

Published in:

PLoS ONE, 2014, v. 9, n. 7, p. 1, doi. 10.1371/journal.pone.0101010

By:

Zhang, Yuwei;
Calado, Rodrigo;
Rao, Mahadev;
Hong, Julie A.;
Meeker, Alan K.;
Dumitriu, Bogdan;
Atay, Scott;
McCormick, Peter J.;
Garfield, Susan H.;
Wangsa, Danny;
Padilla-Nash, Hesed M.;
Burkett, Sandra;
Zhang, Mary;
Kunst, Tricia F.;
Peterson, Nathan R.;
Xi, Sichuan;
Inchauste, Suzanne;
Altorki, Nasser K.;
Casson, Alan G.;
Beer, David G.

Publication type:

Article

Differential long-term stability of microRNAs and RNU6B snRNA in 12-20 year old archived formalin-fixed paraffin-embedded specimens.

Published in:

2017

By:

Peskoe, Sarah B.;
Barber, John R.;
Qizhi Zheng;
Meeker, Alan K.;
De Marzo, Angelo M.;
Platz, Elizabeth A.;
Lupold, Shawn E.;
Zheng, Qizhi

Publication type:

journal article

Leukocyte telomere length and its association with mammographic density and proliferative diagnosis among women undergoing diagnostic image-guided breast biopsy.

Published in:

2015

By:

Bodelon, Clara;
Heaphy, Christopher M.;
Meeker, Alan K.;
Geller, Berta;
Vacek, Pamela M.;
Weaver, Donald L.;
Chicoine, Rachael E.;
Shepherd, John A.;
Mahmoudzadeh, Amir Pasha;
Patel, Deesha A.;
Brinton, Louise A.;
Sherman, Mark E.;
Gierach, Gretchen L.

Publication type:

journal article

Pervasive promoter hypermethylation of silenced TERT alleles in human cancers.

Published in:

Cellular Oncology (2211-3428), 2020, v. 43, n. 5, p. 847, doi. 10.1007/s13402-020-00531-7

By:

Esopi, David;
Graham, Mindy Kim;
Brosnan-Cashman, Jacqueline A.;
Meyers, Jennifer;
Vaghasia, Ajay;
Gupta, Anuj;
Kumar, Balasubramanian;
Haffner, Michael C.;
Heaphy, Christopher M.;
De Marzo, Angelo M.;
Meeker, Alan K.;
Nelson, William G.;
Wheelan, Sarah J.;
Yegnasubramanian, Srinivasan

Publication type:

Article

The Axl receptor tyrosine kinase is an adverse prognostic factor and a therapeutic target in esophageal adenocarcinoma.

Published in:

Cancer Biology & Therapy, 2010, v. 10, n. 10, p. 1009, doi. 10.4161/cbt.10.10.13248

By:

Alvarez, Hector;
Montgomery, Elizabeth A.;
Karikari, Collins;
Canto, Marcia;
Dunbar, Kerry B.;
Wang, Jean S.;
Feldmann, Georg;
Seung-Mo Hong;
Haffner, Michael C.;
Meeker, Alan K.;
Holland, Sacha J.;
Jiaxin Yu;
Heckrodt, Thilo J.;
Jing Zhang;
Pingyu Ding;
Goff, Dane;
Singh, Rajinder;
Roa, Juan Carlos;
Marimuthu, Arivusudar;
Eshleman, James R.

Publication type:

Article

Tracking the clonal origin of lethal prostate cancer.

Published in:

Journal of Clinical Investigation, 2013, v. 123, n. 11, p. 4918, doi. 10.1172/JCI70354

By:

Haffner, Michael C.;
Mosbruger, Timothy;
Esopi, David M.;
Fedor, Helen;
Heaphy, Christopher M.;
Walker, David A.;
Adejola, Nkosi;
Gürel, Meltem;
Hicks, Jessica;
Meeker, Alan K.;
Halushka, Marc K.;
Simons, Jonathan W.;
Isaacs, William B.;
De Marzo, Angelo M.;
Nelson, William G.;
Yegnasubramanian, Srinivasan

Publication type:

Article

Pathological and molecular mechanisms of prostate carcinogenesis: Implications for diagnosis, detection, prevention, and treatment.

Published in:

Journal of Cellular Biochemistry, 2004, v. 91, n. 3, p. 459, doi. 10.1002/jcb.10747

By:

Angelo M. De Marzo;
Theodore L. DeWeese;
Elizabeth A. Platz;
Alan K. Meeker;
Masashi Nakayama;
Jonathan I. Epstein;
William B. Isaacs;
William G. Nelson

Publication type:

Article

Genomic analysis identifies frequent deletions of Dystrophin in olfactory neuroblastoma.

Published in:

Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-07578-z

By:

Gallia, Gary L.;
Zhang, Ming;
Ning, Yi;
Haffner, Michael C.;
Batista, Denise;
Binder, Zev A.;
Bishop, Justin A.;
Hann, Christine L.;
Hruban, Ralph H.;
Ishii, Masaru;
Klein, Alison P.;
Reh, Douglas D.;
Rooper, Lisa M.;
Salmasi, Vafi;
Tamargo, Rafael J.;
Wang, Qing;
Williamson, Tara;
Zhao, Tianna;
Zou, Ying;
Meeker, Alan K.

Publication type:

Article

The potential utility of telomere-related markers for cancer diagnosis.

Published in:

Journal of Cellular & Molecular Medicine, 2011, v. 15, n. 6, p. 1227, doi. 10.1111/j.1582-4934.2011.01284.x

By:

Heaphy, Christopher M.;
Meeker, Alan K.

Publication type:

Article

A fusion protein between serum amyloid A and staphylococcal nuclease-synthesis, purification, and structural studies.

Published in:

Proteins, 1998, v. 30, n. 4, p. 381, doi. 10.1002/(SICI)1097-0134(19980301)30:4<381::AID-PROT5>3.0.CO;2-M

By:

Meeker, Alan K.;
Sack, George H.

Publication type:

Article

Therapeutic Vulnerability to ATR Inhibition in Concurrent NF1 and ATRX -Deficient/ALT-Positive High-Grade Solid Tumors.

Published in:

Cancers, 2022, v. 14, n. 12, p. 3015, doi. 10.3390/cancers14123015

By:

Yuan, Ming;
Eberhart, Charles G.;
Pratilas, Christine A.;
Blakeley, Jaishri O.;
Davis, Christine;
Stojanova, Marija;
Reilly, Karlyne;
Meeker, Alan K.;
Heaphy, Christopher M.;
Rodriguez, Fausto J.

Publication type:

Article

ATRX-Deficient High-Grade Glioma Cells Exhibit Increased Sensitivity to RTK and PDGFR Inhibitors.

Published in:

Cancers, 2022, v. 14, n. 7, p. 1790, doi. 10.3390/cancers14071790

By:

Pladevall-Morera, David;
Castejón-Griñán, María;
Aguilera, Paula;
Gaardahl, Karina;
Ingham, Andreas;
Brosnan-Cashman, Jacqueline A.;
Meeker, Alan K.;
Lopez-Contreras, Andres J.

Publication type:

Article

Longer prostate stromal cell telomere length is associated with increased risk of death from other cancers.

Published in:

Frontiers in Medicine, 2024, p. 1, doi. 10.3389/fmed.2024.1390769

By:

Mori, Joakin O.;
Platz, Elizabeth A.;
Lu, Jiayun;
Brame, Alexandria;
Han, Misop;
Joshu, Corinne E.;
De Marzo, Angelo M.;
Meeker, Alan K.;
Heaphy, Christopher M.

Publication type:

Article

Influence of In Utero Maternal and Neonate Factors on Cord Blood Leukocyte Telomere Length: Clues to the Racial Disparity in Prostate Cancer?

Published in:

Prostate Cancer (20903111), 2016, p. 1, doi. 10.1155/2016/3691650

By:

Weber, Kari A.;
Heaphy, Christopher M.;
Rohrmann, Sabine;
Gonzalez, Beverly;
Bienstock, Jessica L.;
Agurs-Collins, Tanya;
Platz, Elizabeth A.;
Meeker, Alan K.

Publication type:

Article

Mutant forms of staphylococcal nuclease with altered patterns of guanidine hydrochloride and urea denaturation.

Published in:

Proteins, 1986, v. 1, n. 1, p. 81, doi. 10.1002/prot.340010113

By:

Shortle, David;
Meeker, Alan K.

Publication type:

Article

Frontiers in prostate cancer. Telomeres and chaos.

Published in:

Cancer (0008543X), 1995, v. 75, n. S7, p. 2027, doi. 10.1002/1097-0142(19950401)75:7+<2027::AID-CNCR2820751645>3.0.CO;2-6

By:

Sommerfeld, Hans J.;
Meeker, Alan K.;
Posadas, Edwin M.;
Coffey, Donald S.

Publication type:

Article

Global Analysis of BRAFV600E Target Genes in Human Melanocytes Identifies Matrix Metalloproteinase-1 as a Critical Mediator of Melanoma Growth.

Published in:

2011

By:

Ryu, Byungwoo;
Moriarty, Whei F.;
Stine, Megan J.;
DeLuca, Amena;
Kim, Dave S.;
Meeker, Alan K.;
Grills, Landon D.;
Switzer, Rebecca A.;
Eller, Mark S.;
Alani, Rhoda M.

Publication type:

Letter

Adding the Team into T1 Translational Research: A Case Study of Multidisciplinary Team Science in the Evaluation of Biomarkers of Prostate Cancer Risk and Prognosis.

Published in:

Clinical Chemistry, 2019, v. 65, n. 1, p. 189, doi. 10.1373/clinchem.2018.293365

By:

Marrone, Michael T.;
Joshu, Corinne E.;
Peskoe, Sarah B.;
De Marzo, Angelo M.;
Heaphy, Christopher M.;
Lupold, Shawn E.;
Meeker, Alan K.;
Platz, Elizabeth A.

Publication type:

Article

DAXX promotes centromeric stability independently of ATRX by preventing the accumulation of R-loop-induced DNA double-stranded breaks.

Published in:

Nucleic Acids Research, 2024, v. 52, n. 3, p. 1136, doi. 10.1093/nar/gkad1141

By:

Pinto, Lia M;
Pailas, Alexandros;
Bondarchenko, Max;
Sharma, Abhishek Bharadwaj;
Neumann, Katrin;
Rizzo, Anthony J;
Jeanty, Céline;
Nicot, Nathalie;
Racca, Carine;
Graham, Mindy K;
Naughton, Catherine;
Liu, Yaqun;
Chen, Chun-Long;
Meakin, Paul J;
Gilbert, Nick;
Britton, Sébastien;
Meeker, Alan K;
Heaphy, Christopher M;
Larminat, Florence;
Van Dyck, Eric

Publication type:

Article

Downregulation of 5‐hydroxymethylcytosine is an early event in pancreatic tumorigenesis.

Published in:

Journal of Pathology, 2021, v. 254, n. 3, p. 279, doi. 10.1002/path.5682

By:

Fujikura, Kohei;
Alruwaii, Zainab I;
Haffner, Michael C;
Trujillo, Maria A;
Roberts, Nicholas J;
Hong, Seung‐Mo;
Macgregor‐Das, Anne;
Goggins, Michael G;
Roy, Sujayita;
Meeker, Alan K;
Ding, Ding;
Wright, Michael;
He, Jin;
Hruban, Ralph H;
Wood, Laura D

Publication type:

Article

MYC drives overexpression of telomerase RNA ( hTR/ TERC) in prostate cancer.

Published in:

Journal of Pathology, 2018, v. 244, n. 1, p. 11, doi. 10.1002/path.4980

By:

Baena‐Del Valle, Javier A.;
Zheng, Qizhi;
Esopi, David M.;
Rubenstein, Michael;
Hubbard, Gretchen K.;
Moncaliano, Maria C.;
Hruszkewycz, Andrew;
Vaghasia, Ajay;
Yegnasubramanian, Srinivasan;
Wheelan, Sarah J.;
Meeker, Alan K.;
Heaphy, Christopher M.;
Graham, Mindy K.;
De Marzo, Angelo M.

Publication type:

Article

Racial differences in maternal and umbilical cord blood leukocyte telomere length and their correlations.

Published in:

2018

By:

Weber, Kari A.;
Heaphy, Christopher M.;
Joshu, Corinne E.;
Lu, Jiayun;
Rohrmann, Sabine;
Bienstock, Jessica L.;
Agurs-Collins, Tanya;
Meeker, Alan K.;
Platz, Elizabeth A.

Publication type:

journal article

The prostate tissue‐based telomere biomarker as a prognostic tool for metastasis and death from prostate cancer after prostatectomy.

Published in:

Journal of Pathology: Clinical Research, 2022, v. 8, n. 5, p. 481, doi. 10.1002/cjp2.288

By:

Heaphy, Christopher M;
Joshu, Corinne E;
Barber, John R;
Davis, Christine;
Lu, Jiayun;
Zarinshenas, Reza;
Giovannucci, Edward;
Mucci, Lorelei A;
Stampfer, Meir J;
Han, Misop;
De Marzo, Angelo M;
Lotan, Tamara L;
Platz, Elizabeth A;
Meeker, Alan K

Publication type:

Article

Chromogenic detection of telomere lengths in situ aids the identification of precancerous lesions in the prostate.

Published in:

Prostate, 2024, v. 84, n. 2, p. 148, doi. 10.1002/pros.24633

By:

Ertunc, Onur;
Smearman, Erica;
Zheng, Qizhi;
Hicks, Jessica L.;
Brosnan‐Cashman, Jacqueline A.;
Jones, Tracy;
Gomes‐Alexandre, Carolina;
Trabzonlu, Levent;
Meeker, Alan K.;
De Marzo, Angelo M.;
Heaphy, Christopher M.

Publication type:

Article

Tumor‐infiltrating mesenchymal stem cells: Drivers of the immunosuppressive tumor microenvironment in prostate cancer?

Published in:

Prostate, 2019, v. 79, n. 3, p. 320, doi. 10.1002/pros.23738

By:

Krueger, Timothy E.;
Thorek, Daniel L. J.;
Meeker, Alan K.;
Isaacs, John T.;
Brennen, W. Nathaniel

Publication type:

Article

Current or recent smoking is associated with more variable telomere length in prostate stromal cells and prostate cancer cells.

Published in:

Prostate, 2018, v. 78, n. 3, p. 233, doi. 10.1002/pros.23462

By:

Joshu, Corinne E.;
Peskoe, Sarah B.;
Heaphy, Christopher M.;
Kenfield, Stacey A.;
Mucci, Lorelei A.;
Giovannucci, Edward L.;
Stampfer, Meir J.;
Yoon, Ghilsuk;
Lee, Thomas K.;
Hicks, Jessica L.;
De Marzo, Angelo M.;
Meeker, Alan K.;
Platz, Elizabeth A.

Publication type:

Article

Low p16INK4a Expression in Early Passage Human Prostate Basal Epithelial Cells Enables Immortalization by Telomerase Expression Alone.

Published in:

Prostate, 2017, v. 77, n. 4, p. 374, doi. 10.1002/pros.23276

By:

Graham, Mindy Kim;
Principessa, Lorenzo;
Antony, Lizamma;
Meeker, Alan K.;
Isaacs, John T.

Publication type:

Article

Prostate stromal cell telomere shortening is associated with risk of prostate cancer in the placebo arm of the Prostate Cancer Prevention Trial.

Published in:

Prostate, 2015, v. 75, n. 11, p. 1160, doi. 10.1002/pros.22997

By:

Heaphy, Christopher M.;
Gaonkar, Gaurav;
Peskoe, Sarah B.;
Joshu, Corinne E.;
De Marzo, Angelo M.;
Lucia, M. Scott;
Goodman, Phyllis J.;
Lippman, Scott M.;
Thompson, Ian M.;
Platz, Elizabeth A.;
Meeker, Alan K.

Publication type:

Article

Investigation of miR-21, miR-141, and miR-221 expression levels in prostate adenocarcinoma for associated risk of recurrence after radical prostatectomy.

Published in:

Prostate, 2014, v. 74, n. 16, p. 1655, doi. 10.1002/pros.22883

By:

Zheng, Qizhi;
Peskoe, Sarah B.;
Ribas, Judit;
Rafiqi, Fatema;
Kudrolli, Tarana;
Meeker, Alan K.;
De Marzo, Angelo M.;
Platz, Elizabeth A.;
Lupold, Shawn E.

Publication type:

Article

Telomere length as a risk factor for hereditary prostate cancer.

Published in:

Prostate, 2014, v. 74, n. 4, p. 359, doi. 10.1002/pros.22755

By:

Hurwitz, Lauren M.;
Heaphy, Christopher M.;
Joshu, Corinne E.;
Isaacs, William B.;
Konishi, Yuko;
De Marzo, Angelo M.;
Isaacs, Sally D.;
Wiley, Kathy E.;
Platz, Elizabeth A.;
Meeker, Alan K.

Publication type:

Article

Human prostate-infiltrating CD8+ T lymphocytes are oligoclonal and PD-1+.

Published in:

Prostate, 2009, v. 69, n. 15, p. 1694, doi. 10.1002/pros.21020

By:

Sfanos, Karen S.;
Bruno, Tullia C.;
Meeker, Alan K.;
De Marzo, Angelo M.;
Isaacs, William B.;
Drake, Charles G.

Publication type:

Article

Dual-label centromere and telomere FISH identifies human, rat, and mouse cell contribution to Multispecies recombinant urogenital sinus xenografts.

Published in:

Prostate, 2009, v. 69, n. 14, p. 1557, doi. 10.1002/pros.21001

By:

Vander Griend, Donald J.;
Konishi, Yuko;
De Marzo, Angelo M.;
Isaacs, John T.;
Meeker, Alan K.

Publication type:

Article

Id1 delays senescence of primary human melanocytes.

Published in:

Molecular Carcinogenesis, 2008, v. 47, n. 9, p. 653, doi. 10.1002/mc.20422

By:

Cummings, Staci D.;
Ryu, Byungwoo;
Samuels, Michael A.;
Yu, Xiaobing;
Meeker, Alan K.;
Healey, Megan A.;
Alani, Rhoda M.

Publication type:

Article

Evaluation of telomere length in human cardiac tissues using cardiac quantitative FISH.

Published in:

Nature Protocols, 2017, v. 12, n. 9, p. 1855, doi. 10.1038/nprot.2017.082

By:

Sharifi-Sanjani, Maryam;
Meeker, Alan K;
Mourkioti, Foteini

Publication type:

Article

Brief Report: A Bioassay to Identify Primary Human Prostate Cancer Repopulating Cells.

Published in:

Stem Cells, 2011, v. 29, n. 8, p. 1310, doi. 10.1002/stem.668

By:

Toivanen, Roxanne;
Berman, David M.;
Wang, Hong;
Pedersen, John;
Frydenberg, Mark;
Meeker, Alan K.;
Ellem, Stuart J.;
Risbridger, Gail P.;
Taylor, Renea A.

Publication type:

Article

Telomere length shortening in Langerhans cell histiocytosis.

Published in:

British Journal of Haematology, 2008, v. 140, n. 4, p. 420, doi. 10.1111/j.1365-2141.2007.06904.x

By:

Bechan, Gitanjali I.;
Meeker, Alan K.;
De Marzo, Angelo M.;
Racke, Frederick;
Jaffe, Ronald;
Sugar, Elizabeth;
Arceci, Robert J.

Publication type:

Article

Role of telomere dysfunction in cardiac failure in Duchenne muscular dystrophy.

Published in:

Nature Cell Biology, 2013, v. 15, n. 8, p. 895, doi. 10.1038/ncb2790

By:

Mourkioti, Foteini;
Kustan, Jackie;
Kraft, Peggy;
Day, John W.;
Zhao, Ming-Ming;
Kost-Alimova, Maria;
Protopopov, Alexei;
DePinho, Ronald A.;
Bernstein, Daniel;
Meeker, Alan K.;
Blau, Helen M.

Publication type:

Article