Works by Medema, Jan Paul

Results: 72

NanoCMSer: a consensus molecular subtype stratification tool for fresh‐frozen and paraffin‐embedded colorectal cancer samples.

Published in:

Molecular Oncology, 2025, v. 19, n. 5, p. 1332, doi. 10.1002/1878-0261.13781

By:

Torang, Arezo;
van de Weerd, Simone;
Lammers, Veerle;
van Hooff, Sander;
van den Berg, Inge;
van den Bergh, Saskia;
Koopman, Miriam;
IJzermans, Jan N.;
Roodhart, Jeanine M. L.;
Koster, Jan;
Medema, Jan Paul

Publication type:

Article

Specific TLR ligands regulate APRIL secretion by dendritic cells in a PKR-dependent manner.

Published in:

European Journal of Immunology, 2007, v. 37, n. 10, p. 2900, doi. 10.1002/eji.200737210

By:

Hardenberg, Gijs;
Planelles, Lourdes;
Schwarte, Carla M.;
van Bostelen, Liesbeth;
Le Huong, Tran;
Hahne, Michael;
Medema, Jan Paul

Publication type:

Article

Cleavage of FLICE (caspase-8) by granzyme B during cytotoxic T lymphocyte-induced apoptosis.

Published in:

European Journal of Immunology, 1997, v. 27, n. 12, p. 3492, doi. 10.1002/eji.1830271250

By:

Medema, Jan Paul;
Toes, René E. M.;
Scaffidi, Carsten;
Zheng, Timothy S.;
Flavell, Richard A.;
Melief, Cornelius J. M.;
Peter, Marcus E.;
Offringa, Rienk;
Krammer, Peter H.

Publication type:

Article

Resistance of cultured peripheral T cells towards activation-induced cell death involves a lack of recruitment of FLICE (MACH/caspase 8) to the CD95 death-inducing signaling complex.

Published in:

European Journal of Immunology, 1997, v. 27, n. 5, p. 1207, doi. 10.1002/eji.1830270523

By:

Peter, Marcus E.;
Kischkel, Frank C.;
Scheuerpflug, Christian G.;
Medema, Jan Paul;
Debatin, Klaus-Michael;
Krammer, Peter H.

Publication type:

Article

Patched-2 functions to limit Patched-1 deficient skin cancer growth.

Published in:

Cellular Oncology (2211-3428), 2018, v. 41, n. 4, p. 427, doi. 10.1007/s13402-018-0381-9

By:

Veenstra, Veronique L.;
Dingjan, Ilse;
Waasdorp, Cynthia;
Damhofer, Helene;
van der Wal, Allard C.;
van Laarhoven, Hanneke W.;
Medema, Jan Paul;
Bijlsma, Maarten F.

Publication type:

Article

The Role of Cancer-Associated Fibroblasts in Cancer Invasion and Metastasis.

Published in:

Cancers, 2021, v. 13, n. 18, p. 4720, doi. 10.3390/cancers13184720

By:

Asif, Paris Jabeen;
Longobardi, Ciro;
Hahne, Michael;
Medema, Jan Paul

Publication type:

Article

Pre-Operative Decitabine in Colon Cancer Patients: Analyses on WNT Target Methylation and Expression.

Published in:

Cancers, 2021, v. 13, n. 10, p. 2357, doi. 10.3390/cancers13102357

By:

Linnekamp, Janneke F.;
Kandimalla, Raju;
Fessler, Evelyn;
de Jong, Joan H.;
Rodermond, Hans M.;
van Bochove, Gregor G. W.;
The, Frans O.;
Punt, Cornelis J. A.;
Bemelman, Willem A.;
van de Ven, Anthony W. H.;
Tanis, Pieter J.;
Kemper, Elles M.;
Koens, Lianne;
Dekker, Evelien;
Vermeulen, Louis;
van Laarhoven, Hanneke W. M.;
Medema, Jan Paul;
Baiocchi, Marta;
Zeuner, Ann;
Seuningen, Isabelle Van

Publication type:

Article

AKT3 Expression in Mesenchymal Colorectal Cancer Cells Drives Growth and Is Associated with Epithelial-Mesenchymal Transition.

Published in:

Cancers, 2021, v. 13, n. 4, p. 801, doi. 10.3390/cancers13040801

By:

Buikhuisen, Joyce Y.;
Gomez Barila, Patricia M.;
Torang, Arezo;
Dekker, Daniëlle;
de Jong, Joan H.;
Cameron, Kate;
Vitale, Sara;
Stassi, Giorgio;
van Hooff, Sander R.;
Castro, Mauro A. A.;
Vermeulen, Louis;
Medema, Jan Paul;
Louvard, Daniel

Publication type:

Article

Subtype-specific kinase dependency regulates growth and metastasis of poor-prognosis mesenchymal colorectal cancer.

Published in:

Journal of Experimental & Clinical Cancer Research (17569966), 2023, v. 42, n. 1, p. 1, doi. 10.1186/s13046-023-02600-9

By:

Buikhuisen, Joyce Y.;
Gomez Barila, Patricia M.;
Cameron, Kate;
Suijkerbuijk, Saskia J. E.;
Lieftink, Cor;
di Franco, Simone;
Krotenberg Garcia, Ana;
Uceda Castro, Rebeca;
Lenos, Kristiaan J.;
Nijman, Lisanne E.;
Torang, Arezo;
Longobardi, Ciro;
de Jong, Joan H.;
Dekker, Daniëlle;
Stassi, Giorgio;
Vermeulen, Louis;
Beijersbergen, Roderick L.;
van Rheenen, Jacco;
Huveneers, Stephan;
Medema, Jan Paul

Publication type:

Article

Rapid stromal remodeling by short‐term VEGFR2 inhibition increases chemotherapy delivery in esophagogastric adenocarcinoma.

Published in:

Molecular Oncology, 2020, v. 14, n. 4, p. 704, doi. 10.1002/1878-0261.12599

By:

Steins, Anne;
Klaassen, Remy;
Jacobs, Igor;
Schabel, Matthias C.;
Lier, Monique G. J. T. B.;
Ebbing, Eva A.;
Hectors, Stefanie J.;
Tas, Sander W.;
Maracle, Chrissta X.;
Punt, Cornelis J. A.;
Siebes, Maria;
Bergman, Jacques J. G. H. M.;
Medema, Jan Paul;
Wilmink, Johanna W.;
Mathot, Ron A. A.;
Strijkers, Gustav J.;
Bijlsma, Maarten F.;
Laarhoven, Hanneke W. M.

Publication type:

Article

Assessment of the stromal contribution to Sonic Hedgehog-dependent pancreatic adenocarcinoma.

Published in:

Molecular Oncology, 2013, v. 7, n. 6, p. 1031, doi. 10.1016/j.molonc.2013.08.004

By:

Damhofer, Helene;
Medema, Jan Paul;
Veenstra, Veronique L.;
Badea, Liviu;
Popescu, Irinel;
Roelink, Henk;
Bijlsma, Maarten F.

Publication type:

Article

Identification of C/EBPδ‐Modifying Compounds as Potential Anticancer Agents Using a High‐Throughput Drug Screen.

Published in:

Journal of Cellular & Molecular Medicine, 2025, v. 29, n. 3, p. 1, doi. 10.1111/jcmm.70287

By:

Hartl, Leonie;
Duitman, JanWillem;
Aberson, Hella L.;
Medema, Jan Paul;
Bijlsma, Maarten F.;
Spek, C. Arnold

Publication type:

Article

Consensus molecular subtype transition during progression of colorectal cancer.

Published in:

Journal of Pathology, 2023, v. 261, n. 3, p. 298, doi. 10.1002/path.6176

By:

van de Weerd, Simone;
Torang, Arezo;
Zwager, Liselotte W;
Koelink, Pim J;
Koster, Jan;
Bastiaansen, Barbara AJ;
Lammers, Veerle;
Longobardi, Ciro;
Roodhart, Jeanine ML;
van Krieken, J Han;
Farina Sarasqueta, Arantza;
Dekker, Evelien;
Medema, Jan Paul

Publication type:

Article

Tubulin glycylases are required for primary cilia, control of cell proliferation and tumor development in colon.

Published in:

EMBO Journal, 2014, v. 33, n. 22, p. 2735, doi. 10.15252/embj.201490279

By:

Rocha, Cecilia;
Papon, Laura;
Cacheux, Wulfran;
Marques Sousa, Patricia;
Lascano, Valeria;
Tort, Olivia;
Giordano, Tiziana;
Vacher, Sophie;
Lemmers, Benedicte;
Mariani, Pascale;
Meseure, Didier;
Medema, Jan Paul;
Bièche, Ivan;
Hahne, Michael;
Janke, Carsten

Publication type:

Article

Tubulin glycylases are required for primary cilia, control of cell proliferation and tumor development in colon.

Published in:

EMBO Journal, 2014, v. 33, n. 19, p. 2247, doi. 10.15252/embj.201488466

By:

Rocha, Cecilia;
Papon, Laura;
Cacheux, Wulfran;
Marques Sousa, Patricia;
Lascano, Valeria;
Tort, Olivia;
Giordano, Tiziana;
Vacher, Sophie;
Lemmers, Benedicte;
Mariani, Pascale;
Meseure, Didier;
Medema, Jan Paul;
Bièche, Ivan;
Hahne, Michael;
Janke, Carsten

Publication type:

Article

Axing Wnt signals.

Published in:

Cell Research, 2012, v. 22, n. 1, p. 9, doi. 10.1038/cr.2011.141

By:

De Sousa E Melo, Felipe;
Medema, Jan Paul

Publication type:

Article

Serum-based measurements of stromal activation through ADAM12 associate with poor prognosis in colorectal cancer.

Published in:

2022

By:

Ten Hoorn, Sanne;
Waasdorp, Cynthia;
van Oijen, Martijn G H;
Damhofer, Helene;
Trinh, Anne;
Zhao, Lan;
Smits, Lisanne J H;
Bootsma, Sanne;
van Pelt, Gabi W;
Mesker, Wilma E;
Mol, Linda;
Goey, Kaitlyn K H;
Koopman, Miriam;
Medema, Jan Paul;
Tuynman, Jurriaan B;
Zlobec, Inti;
Punt, Cornelis J A;
Vermeulen, Louis;
Bijlsma, Maarten F

Publication type:

journal article

A Method to Study Migration and Invasion of Mouse Intestinal Organoids.

Published in:

Organoids, 2024, v. 3, n. 3, p. 194, doi. 10.3390/organoids3030013

By:

Wouters, Valérie M.;
Longobardi, Ciro;
Medema, Jan Paul

Publication type:

Article

Cancer stem cells: The challenges ahead.

Published in:

Nature Cell Biology, 2013, v. 15, n. 4, p. 338, doi. 10.1038/ncb2717

By:

Medema, Jan Paul

Publication type:

Article

Wnt activity defines colon cancer stem cells and is regulated by the microenvironment.

Published in:

Nature Cell Biology, 2010, v. 12, n. 5, p. 468, doi. 10.1038/ncb2048

By:

Vermeulen, Louis;
De Sousa E Melo, Felipe;
van der Heijden, Maartje;
Cameron, Kate;
de Jong, Joan H.;
Borovski, Tijana;
Tuynman, Jurriaan B.;
Todaro, Matilde;
Merz, Christian;
Rodermond, Hans;
Sprick, Martin R.;
Kemper, Kristel;
Richel, Dick J.;
Stassi, Giorgio;
Medema, Jan Paul

Publication type:

Article

Chromosome instability: lessons from HIV.

Published in:

Nature Cell Biology, 2002, v. 4, n. 8, p. E191, doi. 10.1038/ncb0802-e191b

By:

Medema, Jan Paul;
Medema, René H.

Publication type:

Article

TGFβ signaling directs serrated adenomas to the mesenchymal colorectal cancer subtype.

Published in:

EMBO Molecular Medicine, 2016, v. 8, n. 7, p. 745, doi. 10.15252/emmm.201606184

By:

Fessler, Evelyn;
Drost, Jarno;
Hooff, Sander R;
Linnekamp, Janneke F;
Wang, Xin;
Jansen, Marnix;
De Sousa E Melo, Felipe;
Prasetyanti, Pramudita R;
IJspeert, Joep EG;
Franitza, Marek;
Nürnberg, Peter;
Noesel, Carel JM;
Dekker, Evelien;
Vermeulen, Louis;
Clevers, Hans;
Medema, Jan Paul

Publication type:

Article

Loss of KCNQ1 expression in stage II and stage III colon cancer is a strong prognostic factor for disease recurrence.

Published in:

2016

By:

den Uil, Sjoerd H;
Coupé, Veerle M H;
Linnekamp, Janneke F;
van den Broek, Evert;
Goos, Jeroen A C M;
Delis-van Diemen, Pien M;
Belt, Eric J Th;
van Grieken, Nicole C T;
Scott, Patricia M;
Vermeulen, Louis;
Medema, Jan Paul;
Bril, Herman;
Stockmann, Hein B A C;
Cormier, Robert T;
Meijer, Gerrit A;
Fijneman, Remond J A;
Coupé, Veerle M H

Publication type:

journal article

RNF43 truncations trap CK1 to drive niche‐independent self‐renewal in cancer.

Published in:

EMBO Journal, 2020, v. 39, n. 18, p. 1, doi. 10.15252/embj.2019103932

By:

Spit, Maureen;
Fenderico, Nicola;
Jordens, Ingrid;
Radaszkiewicz, Tomasz;
Lindeboom, Rik GH;
Bugter, Jeroen M;
Cristobal, Alba;
Ootes, Lars;
van Osch, Max;
Janssen, Eline;
Boonekamp, Kim E;
Hanakova, Katerina;
Potesil, David;
Zdrahal, Zbynek;
Boj, Sylvia F;
Medema, Jan Paul;
Bryja, Vitezslav;
Koo, Bon‐Kyoung;
Vermeulen, Michiel;
Maurice, Madelon M

Publication type:

Article

The proteoglycan (heparan sulfate proteoglycan) binding domain of APRIL serves as a platform for ligand multimerization and cross-linking.

Published in:

FASEB Journal, 2009, v. 23, n. 5, p. 1584, doi. 10.1096/fj.08-124669

By:

Kimberley, Fiona C.;
van Bostelen, Liesbeth;
Cameron, Katherine;
Hardenberg, Gijs;
Marquart, J. Arnoud;
Hahne, Michael;
Medema, Jan Paul

Publication type:

Article

Establishment of patient-derived xenograft models and cell lines for malignancies of the upper gastrointestinal tract.

Published in:

Journal of Translational Medicine, 2015, v. 13, n. 1, p. 1, doi. 10.1186/s12967-015-0469-1

By:

Damhofer, Helene;
Ebbing, Eva A.;
Steins, Anne;
Welling, Lieke;
Tol, Johanna A.;
Krishnadath, Kausilia K.;
van Leusden, Tom;
van de Vijver, Marc J.;
Besselink, Marc G.;
Busch, Olivier R.;
van Berge Henegouwen, Mark I.;
van Delden, Otto;
Meijer, Sybren L.;
Dijk, Frederike;
Medema, Jan Paul;
van Laarhoven, Hanneke W.;
Bijlsma, Maarten F.

Publication type:

Article

Endothelial cells induce cancer stem cell features in differentiated glioblastoma cells via bFGF.

Published in:

Molecular Cancer, 2015, v. 14, n. 1, p. 1, doi. 10.1186/s12943-015-0420-3

By:

Fessler, Evelyn;
Borovski, Tijana;
Medema, Jan Paul

Publication type:

Article

Endothelial cells induce cancer stem cell features in differentiated glioblastoma cells via bFGF.

Published in:

Molecular Cancer, 2015, v. 14, n. 1, p. 157, doi. 10.1186/s12943-015-0420-3

By:

Fessler, Evelyn;
Borovski, Tijana;
Medema, Jan Paul

Publication type:

Article

Regulation of stem cell self-renewal and differentiation by Wnt and Notch are conserved throughout the adenoma-carcinoma sequence in the colon.

Published in:

Molecular Cancer, 2013, v. 12, n. 1, p. 1, doi. 10.1186/1476-4598-12-126

By:

Prasetyanti, Pramudita Ramadhina;
Zimberlin, Cheryl Doreen;
Bots, Michael;
Vermeulen, Louis;
De Sousa E. Melo, Felipe;
Medema, Jan Paul

Publication type:

Article

“APRIL hath put a spring of youth in everything”: Relevance of APRIL for survival.

Published in:

Journal of Cellular Physiology, 2009, v. 218, n. 1, p. 1, doi. 10.1002/jcp.21561

By:

Kimberley, Fiona C.;
Hahne, Michael;
Medema, Jan Paul

Publication type:

Article

Microenvironmental regulation of stem cells in intestinal homeostasis and cancer.

Published in:

Nature, 2011, v. 474, n. 7351, p. 318, doi. 10.1038/nature10212

By:

Medema, Jan Paul;
Vermeulen, Louis

Publication type:

Article

High‐grade mesenchymal pancreatic ductal adenocarcinoma drives stromal deactivation through CSF‐1.

Published in:

EMBO Reports, 2020, v. 21, n. 5, p. 1, doi. 10.15252/embr.201948780

By:

Steins, Anne;
van Mackelenbergh, Madelaine G;
van der Zalm, Amber P;
Klaassen, Remy;
Serrels, Bryan;
Goris, Sandrine G;
Kocher, Hemant M;
Waasdorp, Cynthia;
de Jong, Joan H;
Tekin, Cansu;
Besselink, Marc G;
Busch, Olivier R;
van de Vijver, Marc J;
Verheij, Joanne;
Dijk, Frederike;
van Tienhoven, Geertjan;
Wilmink, Johanna W;
Medema, Jan Paul;
van Laarhoven, Hanneke WM;
Bijlsma, Maarten F

Publication type:

Article

Cancer heterogeneity-a multifaceted view.

Published in:

EMBO Reports, 2013, v. 14, n. 8, p. 686, doi. 10.1038/embor.2013.92

By:

Melo, Felipe De Sousa E;
Vermeulen, Louis;
Fessler, Evelyn;
Medema, Jan Paul

Publication type:

Article

Enterocyte-like differentiation defines metabolic gene signatures of CMS3 colorectal cancers and provides therapeutic vulnerability.

Published in:

Nature Communications, 2025, v. 16, p. 1, doi. 10.1038/s41467-024-55574-3

By:

Torang, Arezo;
Kirov, Aleksandar B.;
Lammers, Veerle;
Cameron, Kate;
Wouters, Valérie M.;
Jackstadt, Rene F.;
Lannagan, Tamsin R. M.;
de Jong, Joan H.;
Koster, Jan;
Sansom, Owen;
Medema, Jan Paul

Publication type:

Article

Benefit of adjuvant chemotherapy on recurrence free survival per consensus molecular subtype in stage III colon cancer.

Published in:

International Journal of Cancer, 2025, v. 156, n. 2, p. 456, doi. 10.1002/ijc.35120

By:

van de Weerd, Simone;
Torang, Arezo;
van den Berg, Inge;
Lammers, Veerle;
van den Bergh, Saskia;
Brouwer, Nelleke;
Nagtegaal, Iris D.;
Koopman, Miriam;
Vink, Geraldine R.;
van der Baan, Frederieke H.;
van Krieken, Han;
Koster, Jan;
Ijzermans, Jan N.;
Roodhart, Jeanine M. L.;
Medema, Jan Paul

Publication type:

Article

Serum levels of iCAF‐derived osteoglycin predict favorable outcome in pancreatic cancer.

Published in:

International Journal of Cancer, 2023, v. 152, n. 3, p. 511, doi. 10.1002/ijc.34276

By:

Dings, Mark P. G.;
Manoukian, Paul;
Waasdorp, Cynthia;
Quik, Judith S. E.;
Strijker, Marin;
Lodestijn, Sophie C.;
van Neerven, Sanne M.;
Moreno, Leandro F.;
de Oliveira, Rodrigo Leite;
Bonsing, Bert A.;
Bruno, Marco J.;
Busch, Olivier R.;
Doukas, Michael;
van Eijck, Casper H.;
Mohammad, Nadia Haj;
de Hingh, Ignace H.;
Molenaar, Quintus I.;
Besselink, Marc G.;
Vermeulen, Louis;
Medema, Jan Paul

Publication type:

Article

Systemic effects of angiogenesis inhibition alter pharmacokinetics and intratumoral delivery of nab -paclitaxel.

Published in:

Drug Delivery, 2017, v. 24, n. 1, p. 1801, doi. 10.1080/10717544.2017.1406559

By:

Steins, Anne;
Ebbing, Eva A.;
Pistorius, Marcel C. M.;
Waasdorp, Cynthia;
Krishnadath, Kausilia K.;
Medema, Jan Paul;
Wilmink, Johanna W.;
Mathôt, Ron A. A.;
Bijlsma, Maarten F.;
van Laarhoven, Hanneke W. M.

Publication type:

Article

Poor-prognosis colon cancer is defined by a molecularly distinct subtype and develops from serrated precursor lesions.

Published in:

Nature Medicine, 2013, v. 19, n. 5, p. 614, doi. 10.1038/nm.3174

By:

De Sousa E Melo, Felipe;
Wang, Xin;
Jansen, Marnix;
Fessler, Evelyn;
Trinh, Anne;
de Rooij, Laura P M H;
de Jong, Joan H;
de Boer, Onno J;
van Leersum, Ronald;
Bijlsma, Maarten F;
Rodermond, Hans;
van der Heijden, Maartje;
van Noesel, Carel J M;
Tuynman, Jurriaan B;
Dekker, Evelien;
Markowetz, Florian;
Medema, Jan Paul;
Vermeulen, Louis

Publication type:

Article

Sequential cancer mutations in cultured human intestinal stem cells.

Published in:

Nature, 2015, v. 521, n. 7550, p. 43, doi. 10.1038/nature14415

By:

Drost, Jarno;
van Jaarsveld, Richard H.;
Ponsioen, Bas;
Zimberlin, Cheryl;
van Boxtel, Ruben;
Buijs, Arjan;
Sachs, Norman;
Overmeer, René M.;
Offerhaus, G. Johan;
Begthel, Harry;
Korving, Jeroen;
van de Wetering, Marc;
Schwank, Gerald;
Logtenberg, Meike;
Cuppen, Edwin;
Snippert, Hugo J.;
Medema, Jan Paul;
Kops, Geert J. P. L.;
Clevers, Hans

Publication type:

Article

Unsupervised class discovery in pancreatic ductal adenocarcinoma reveals cell-intrinsic mesenchymal features and high concordance between existing classification systems.

Published in:

Scientific Reports, 2020, v. 10, n. 1, p. 1, doi. 10.1038/s41598-019-56826-9

By:

Dijk, Frederike;
Veenstra, Veronique L.;
Soer, Eline C.;
Dings, Mark P. G.;
Zhao, Lan;
Halfwerk, Johannes B.;
Hooijer, Gerrit K.;
Damhofer, Helene;
Marzano, Marco;
Steins, Anne;
Waasdorp, Cynthia;
Busch, Olivier R.;
Besselink, Marc G.;
Tol, Johanna A.;
Welling, Lieke;
van Rijssen, Lennart B.;
Klompmaker, Sjors;
Wilmink, Hanneke W.;
van Laarhoven, Hanneke W.;
Medema, Jan Paul

Publication type:

Article

Expression and Function of Granzymes A and B in Escherichia coli Peritonitis and Sepsis.

Published in:

Mediators of Inflammation, 2017, p. 1, doi. 10.1155/2017/4137563

By:

García-Laorden, M. Isabel;
Stroo, Ingrid;
Terpstra, Sanne;
Florquin, Sandrine;
Medema, Jan Paul;
van´t Veer, Cornelis;
de Vos, Alex F.;
van der Poll, Tom

Publication type:

Article

Thymus-independent class switch recombination is affected by APRIL.

Published in:

Immunology & Cell Biology, 2008, v. 86, n. 6, p. 530, doi. 10.1038/icb.2008.17

By:

Hardenberg, Gijs;
van Bostelen, Liesbeth;
Hahne, Michael;
Medema, Jan Paul

Publication type:

Article

Serpins prevent granzyme-induced death in a species-specific manner.

Published in:

Immunology & Cell Biology, 2006, v. 84, n. 1, p. 79, doi. 10.1111/j.1440-1711.2005.01417.x

By:

BOTS, MICHAEL;
VAN BOSTELEN, LIESBETH;
RADEMAKER, MIRJAM TGA;
OFFRINGA, RIENK;
MEDEMA, JAN PAUL

Publication type:

Article

Granzymes A and B Regulate the Local Inflammatory Response during Klebsiella pneumoniae Pneumonia.

Published in:

Journal of Innate Immunity, 2016, v. 8, n. 3, p. 258, doi. 10.1159/000443401

By:

García-Laorden, M. Isabel;
Stroo, Ingrid;
Blok, Dana C.;
Florquin, Sandrine;
Medema, Jan Paul;
de Vos, alex F.;
van der Poll, Tom

Publication type:

Article

Relationship Between Ultraviolet Radiation--Induced Immunosuppression and Carcinogenesis.

Published in:

Journal of Investigative Dermatology, 1994, v. 103, p. 107S, doi. 10.1038/jid.1994.19

By:

Streilein, J. Wayne;
Taylor, J. Richard;
Vincek, Vladimir;
Kurimoto, Iwao;
Richardson, Jeff;
Tie, Cynthia;
Medema, Jan-Paul;
Golomb, Cindy

Publication type:

Article

FLICE is activated by association with the CD95 death-inducing signaling complex (DISC).

Published in:

EMBO Journal, 1997, v. 16, n. 10, p. 2794, doi. 10.1093/emboj/16.10.2794

By:

Medema, Jan Paul;
Scaffidi, Carsten;
Kischkel, Frank C.;
Shevchenko, Andrej;
Mann, Matthias;
Krammer, Peter H.;
Peter, Marcus E.

Publication type:

Article

Correlation of Immunological and Histopathological Features with Gene Expression-Based Classifiers in Colon Cancer Patients.

Published in:

International Journal of Molecular Sciences, 2022, v. 23, n. 20, p. 12707, doi. 10.3390/ijms232012707

By:

van de Weerd, Simone;
Smit, Marloes A.;
Roelands, Jessica;
Mesker, Wilma E.;
Bedognetti, Davide;
Kuppen, Peter J. K.;
Putter, Hein;
Tollenaar, Rob A. E. M.;
Roodhart, Jeanine M. L.;
Hendrickx, Wouter;
Medema, Jan Paul;
van Krieken, J. Han J. M.

Publication type:

Article

BH3 Mimetic Sensitivity of Colorectal Cancer Cell Lines in Correlation with Molecular Features Identifies Predictors of Response.

Published in:

International Journal of Molecular Sciences, 2021, v. 22, n. 8, p. 3811, doi. 10.3390/ijms22083811

By:

Zhang, Le;
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Publication type:

Article

Life and death in a flash.

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Nature, 1999, v. 398, n. 6730, p. 756, doi. 10.1038/19638

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Nature Communications, 2016, v. 7, n. 3, p. 10916, doi. 10.1038/ncomms10916

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van der Heijden, Maartje;
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Kemp, Richard;
Meijer, Sybren L.;
Medema, Jan Paul;
Greten, Florian R.;
Jansen, Marnix;
Winton, Douglas J.;
Vermeulen, Louis

Publication type:

Article