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Safe drugs with high potential to block malaria transmission revealed by a spleen-mimetic screening.
- Published in:
- Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-37359-2
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- Article
A high-throughput phenotypic screen identifies clofazimine as a potential treatment for cryptosporidiosis.
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- PLoS Neglected Tropical Diseases, 2017, v. 11, n. 2, p. 1, doi. 10.1371/journal.pntd.0005373
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- Article
Determining the Relationship Between Clofazimine Gastrointestinal Levels and anti‐CryptosporidiumEfficacy in Mice.
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- FASEB Journal, 2022, v. 36, p. N.PAG, doi. 10.1096/fasebj.2022.36.S1.R4981
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- Article
Bicyclic azetidines kill the diarrheal pathogen Cryptosporidium in mice by inhibiting parasite phenylalanyl-tRNA synthetase.
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- Science Translational Medicine, 2020, v. 12, n. 563, p. 1, doi. 10.1126/scitranslmed.aba8412
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- Article
Protein target similarity is positive predictor of in vitro antipathogenic activity: a drug repurposing strategy for Plasmodium falciparum.
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- Journal of Cheminformatics, 2024, v. 16, n. 1, p. 1, doi. 10.1186/s13321-024-00856-7
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- Article
Identification of pathogen genomic variants through an integrated pipeline.
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- BMC Bioinformatics, 2014, v. 15, n. 1, p. 1, doi. 10.1186/1471-2105-15-63
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- Article
Utilizing Chemical Genomics to Identify Cytochrome b as a Novel Drug Target for Chagas Disease.
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- PLoS Pathogens, 2015, v. 11, n. 7, p. 1, doi. 10.1371/journal.ppat.1005058
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- Article
Mitotic Evolution of Plasmodium falciparum Shows a Stable Core Genome but Recombination in Antigen Families.
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- PLoS Genetics, 2013, v. 9, n. 2, p. 1, doi. 10.1371/journal.pgen.1003293
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- Article
A suite of phenotypic assays to ensure pipeline diversity when prioritizing drug-like Cryptosporidium growth inhibitors.
- Published in:
- Nature Communications, 2019, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41467-019-09880-w
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- Article
A comprehensive model for assessment of liverstage therapies targetingPlasmodium vivaxandPlasmodium falciparum.
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- Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-04221-9
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- Article
Targeting Plasmodium PI(4)K to eliminate malaria.
- Published in:
- Nature, 2013, v. 504, n. 7479, p. 248, doi. 10.1038/nature12782
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- Article
An Integrated Approach to Identify New Anti-Filarial Leads to Treat River Blindness, a Neglected Tropical Disease.
- Published in:
- Pathogens, 2021, v. 10, n. 1, p. 71, doi. 10.3390/pathogens10010071
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- Article
Drug Discovery for Cutaneous Leishmaniasis: A Review of Developments in the Past 15 Years.
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- Microorganisms, 2023, v. 11, n. 12, p. 2845, doi. 10.3390/microorganisms11122845
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- Article
High-Throughput Screening of the ReFRAME Library Identifies Potential Drug Repurposing Candidates for Trypanosoma cruzi.
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- Microorganisms, 2020, v. 8, n. 4, p. 472, doi. 10.3390/microorganisms8040472
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- Article
Comparative chemical genomics reveal that the spiroindolone antimalarial KAE609 (Cipargamin) is a P-type ATPase inhibitor.
- Published in:
- Scientific Reports, 2016, p. 27806, doi. 10.1038/srep27806
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- Article
Comparative chemical genomics reveal that the spiroindolone antimalarial KAE609 (Cipargamin) is a P-type ATPase inhibitor.
- Published in:
- Scientific Reports, 2016, v. 6, n. 1, p. 1, doi. 10.1038/srep27806
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- Article
M1 Protein Allows Group A Streptococcal Survival in Phagocyte Extracellular Traps through Cathelicidin Inhibition.
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- Journal of Innate Immunity, 2009, v. 1, n. 3, p. 202, doi. 10.1159/000203645
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- Article
Cryptosporidium life cycle small molecule probing implicates translational repression and an Apetala 2 transcription factor in macrogamont differentiation.
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- PLoS Pathogens, 2024, v. 20, n. 4, p. 1, doi. 10.1371/journal.ppat.1011906
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- Article
Identification of a potent benzoxaborole drug candidate for treating cryptosporidiosis.
- Published in:
- Nature Communications, 2019, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41467-019-10687-y
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- Article
Pharmacological and genetic activation of cAMP synthesis disrupts cholesterol utilization in Mycobacterium tuberculosis.
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- PLoS Pathogens, 2022, v. 18, n. 2, p. 1, doi. 10.1371/journal.ppat.1009862
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- Article
The Deconstructed Granuloma: A Complex High-Throughput Drug Screening Platform for the Discovery of Host-Directed Therapeutics Against Tuberculosis.
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- Frontiers in Cellular & Infection Microbiology, 2018, v. 8, p. N.PAG, doi. 10.3389/fcimb.2018.00275
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- Article
Antimalarial Peptide and Polyketide Natural Products from the Fijian Marine Cyanobacterium Moorea producens.
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- Marine Drugs, 2020, v. 18, n. 3, p. 167, doi. 10.3390/md18030167
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- Article