Preclinical and Phase 1 Assessment of Antisense Oligonucleotide Bepirovirsen in Hepatitis B Virus–Transgenic Mice and Healthy Human Volunteers: Support for Clinical Dose Selection and Evaluation of Safety, Tolerability, and Pharmacokinetics of Single and Multiple Doses

Published in:

Clinical Pharmacology in Drug Development, 2022, v. 11, n. 10, p. 1191, doi. 10.1002/cpdd.1154

By:

• Han, Kelong;
• Theodore, Dickens;
• McMullen, Gina;
• Swayze, Eric;
• McCaleb, Michael;
• Billioud, Gaetan;
• Wieland, Stefan;
• Hood, Steve;
• Paff, Melanie;
• Bennett, C. Frank;
• Kwoh, T. Jesse

Publication type:

Article