Works by McLean, Pamela J.

Results: 51

Tyrosine and serine phosphorylation of alpha-synuclein have opposing effects on neurotoxicity and soluble oligomer formation.

Published in:

2009

By:

Li Chen;
Periquet, Magali;
Xu Wang;
Alessandro Negro;
Pamela J. McLean;
Bradley T. Hyman;
Mel B. Feany;
Chen, Li;
Wang, Xu;
Negro, Alessandro;
McLean, Pamela J;
Hyman, Bradley T;
Feany, Mel B

Publication type:

journal article

Widespread distribution of α-synuclein oligomers in LRRK2-related Parkinson's disease.

Published in:

Acta Neuropathologica, 2025, v. 149, n. 1, p. 1, doi. 10.1007/s00401-025-02872-9

By:

Sekiya, Hiroaki;
Franke, Lukas;
Hashimoto, Yuki;
Takata, Mariko;
Nishida, Katsuya;
Futamura, Naonobu;
Hasegawa, Kazuko;
Kowa, Hisatomo;
Ross, Owen A.;
McLean, Pamela J.;
Toda, Tatsushi;
Wszolek, Zbigniew K.;
Dickson, Dennis W.

Publication type:

Article

Neonatal AAV delivery of alpha-synuclein induces pathology in the adult mouse brain.

Published in:

Acta Neuropathologica Communications, 2017, v. 5, p. 1, doi. 10.1186/s40478-017-0455-3

By:

Delenclos, Marion;
Faroqi, Ayman H.;
Mei Yue;
Kurti, Aishe;
Castanedes-Casey, Monica;
Rousseau, Linda;
Phillips, Virginia;
Dickson, Dennis W.;
Fryer, John D.;
McLean, Pamela J.

Publication type:

Article

Optimizing SH-SY5Y cell culture: exploring the beneficial effects of an alternative media supplement on cell proliferation and viability.

Published in:

Scientific Reports, 2024, v. 14, n. 1, p. 1, doi. 10.1038/s41598-024-55516-5

By:

Kaya, Zeynep Bengisu;
Santiago-Padilla, Valeria;
Lim, Melina;
Boschen, Suelen L.;
Atilla, Pergin;
McLean, Pamela J.

Publication type:

Article

Alpha‐synuclein‐associated changes in PINK1‐PRKN‐mediated mitophagy are disease context dependent.

Published in:

Brain Pathology, 2023, v. 33, n. 5, p. 1, doi. 10.1111/bpa.13175

By:

Hou, Xu;
Chen, Taylor Hsuan‐Yu;
Koga, Shunsuke;
Bredenberg, Jenny M.;
Faroqi, Ayman H.;
Delenclos, Marion;
Bu, Guojun;
Wszolek, Zbigniew K.;
Carr, Jonathan A.;
Ross, Owen A.;
McLean, Pamela J.;
Murray, Melissa E.;
Dickson, Dennis W.;
Fiesel, Fabienne C.;
Springer, Wolfdieter

Publication type:

Article

Increased Immune Activation by Pathologic α-Synuclein in Parkinson's Disease.

Published in:

2019

By:

Grozdanov, Veselin;
Bousset, Luc;
Hoffmeister, Meike;
Bliederhaeuser, Corinna;
Meier, Christoph;
Madiona, Karine;
Pieri, Laura;
Kiechle, Martin;
McLean, Pamela J.;
Kassubek, Jan;
Behrends, Christian;
Ludolph, Albert C.;
Weishaupt, Jochen H.;
Melki, Ronald;
Danzer, Karin M.

Publication type:

journal article

Mutual exacerbation of peroxisome proliferator-activated receptor γ coactivator 1α deregulation and α-synuclein oligomerization.

Published in:

2015

By:

Eschbach, Judith;
von Einem, Björn;
Müller, Kathrin;
Bayer, Hanna;
Scheffold, Annika;
Morrison, Bradley E;
Rudolph, K Lenhard;
Thal, Dietmar R;
Witting, Anke;
Weydt, Patrick;
Otto, Markus;
Fauler, Michael;
Liss, Birgit;
McLean, Pamela J;
Spada, Albert R La;
Ludolph, Albert C;
Weishaupt, Jochen H;
Danzer, Karin M

Publication type:

journal article

Mutual exacerbation of peroxisome proliferator-activated receptor γ coactivator 1α deregulation and α-synuclein oligomerization.

Published in:

Annals of Neurology, 2015, v. 77, n. 1, p. 15, doi. 10.1002/ana.24294

By:

Eschbach, Judith;
von Einem, Björn;
Müller, Kathrin;
Bayer, Hanna;
Scheffold, Annika;
Morrison, Bradley E.;
Rudolph, K. Lenhard;
Thal, Dietmar R.;
Witting, Anke;
Weydt, Patrick;
Otto, Markus;
Fauler, Michael;
Liss, Birgit;
McLean, Pamela J.;
Spada, Albert R. La;
Ludolph, Albert C.;
Weishaupt, Jochen H.;
Danzer, Karin M.

Publication type:

Article

α-Synuclein oligomers and clinical implications for Parkinson disease.

Published in:

2013

By:

Kalia, Lorraine V;
Kalia, Suneil K;
McLean, Pamela J;
Lozano, Andres M;
Lang, Anthony E

Publication type:

journal article

α-Synuclein oligomers and clinical implications for Parkinson disease.

Published in:

Annals of Neurology, 2013, v. 73, n. 2, p. 155, doi. 10.1002/ana.23746

By:

Kalia, Lorraine V.;
Kalia, Suneil K.;
McLean, Pamela J.;
Lozano, Andres M.;
Lang, Anthony E.

Publication type:

Article

Transcriptional mutagenesis of α-synuclein caused by DNA oxidation in Parkinson's disease pathogenesis.

Published in:

Acta Neuropathologica, 2023, v. 146, n. 5, p. 685, doi. 10.1007/s00401-023-02632-7

By:

Basu, Sambuddha;
Song, Minkyung;
Adams, Levi;
Jeong, Inhye;
Je, Goun;
Guhathakurta, Subhrangshu;
Jiang, Jennifer;
Boparai, Nikpreet;
Dai, Wei;
Cardozo-Pelaez, Fernando;
Tatulian, Suren A.;
Han, Kyu Young;
Elliott, Jordan;
Baum, Jean;
McLean, Pamela J.;
Dickson, Dennis W.;
Kim, Yoon-Seong

Publication type:

Article

APOE4 exacerbates α-synuclein seeding activity and contributes to neurotoxicity in Alzheimer's disease with Lewy body pathology.

Published in:

Acta Neuropathologica, 2022, v. 143, n. 6, p. 641, doi. 10.1007/s00401-022-02421-8

By:

Jin, Yunjung;
Li, Fuyao;
Sonoustoun, Berkiye;
Kondru, Naveen Chandra;
Martens, Yuka A.;
Qiao, Wenhui;
Heckman, Michael G.;
Ikezu, Tadafumi C.;
Li, Zonghua;
Burgess, Jeremy D.;
Amerna, Danilyn;
O'Leary, Justin;
DeTure, Michael A.;
Zhao, Jing;
McLean, Pamela J.;
Dickson, Dennis W.;
Ross, Owen A.;
Bu, Guojun;
Zhao, Na

Publication type:

Article

Investigating the Pathogenic Interplay of Alpha-Synuclein, Tau, and Amyloid Beta in Lewy Body Dementia: Insights from Viral-Mediated Overexpression in Transgenic Mouse Models.

Published in:

Biomedicines, 2023, v. 11, n. 10, p. 2863, doi. 10.3390/biomedicines11102863

By:

Lim, Melina J.;
Boschen, Suelen L.;
Kurti, Aishe;
Castanedes Casey, Monica;
Phillips, Virginia R.;
Fryer, John D.;
Dickson, Dennis;
Jansen-West, Karen R.;
Petrucelli, Leonard;
Delenclos, Marion;
McLean, Pamela J.

Publication type:

Article

Honokiol decreases alpha-synuclein mRNA levels and reveals novel targets for modulating alpha-synuclein expression.

Published in:

Frontiers in Aging Neuroscience, 2023, p. 01, doi. 10.3389/fnagi.2023.1179086

By:

Fagen, Sara J.;
Burgess, Jeremy D.;
Lim, Melina J.;
Amerna, Danilyn;
Kaya, Zeynep B.;
Faroqi, Ayman H.;
Perisetla, Priyanka;
DeMeo, Natasha N.;
Stojkovska, Iva;
Quiriconi, Drew J.;
Mazzull, Joseph R.;
Delenclos, Marion;
Boschen, Suelen L.;
McLean, Pamela J.

Publication type:

Article

Dendritic Spine Abnormalities in Amyloid Precursor Protein Transgenic Mice Demonstrated by Gene Transfer and Intravital Multiphoton Microscopy.

Published in:

Journal of Neuroscience, 2005, v. 25, n. 31, p. 7278, doi. 10.1523/JNEUROSCI.1879-05.2005

By:

Spires, Tara L.;
Meyer-Luehmann, Melanie;
Stern, Edward A.;
McLean, Pamela J.;
Skoch, Jesse;
Nguyen, Paul T.;
Bacskai, Brian J.;
Hyman, Bradley T.

Publication type:

Article

Heat-shock protein 70 modulates toxic extracellular α-synuclein oligomers and rescues trans-synaptic toxicity.

Published in:

FASEB Journal, 2011, v. 25, n. 1, p. 326, doi. 10.1096/fj.10-164624

By:

Danzer, Karin M.;
Ruf, Wolfgang P.;
Putcha, Preeti;
Joyner, Daniel;
Hashimoto, Tadafumi;
Glabe, Charles;
Hyman, Bradley T.;
McLean, Pamela J.

Publication type:

Article

Detection of novel intracellular α-synuclein oligomeric species by fluorescence lifetime imaging.

Published in:

FASEB Journal, 2006, v. 20, n. 12, p. 2050, doi. 10.1096/fj.05-5422com

By:

Klucken, Jochen;
Outeiro, Tiago F.;
Nguyen, Paul;
McLean, Pamela J.;
Hyman, Bradley T.

Publication type:

Article

14-3-3 Proteins Reduce Cell-to-Cell Transfer and Propagation of Pathogenic α-Synuclein.

Published in:

Journal of Neuroscience, 2018, v. 38, n. 38, p. 8211, doi. 10.1523/JNEUROSCI.1134-18.2018

By:

Bing Wang;
Underwood, Rachel;
Kamath, Anjali;
Britain, Colleen;
McFerrin, Michael B.;
Volpicelli-Daley, Laura A.;
Yacoubian, Talene A.;
McLean, Pamela J.;
Whitaker, Robert H.;
Placzek, William J.;
Becker, Katelyn;
Jiyan Ma

Publication type:

Article

Chaperones in Neurodegeneration.

Published in:

Journal of Neuroscience, 2015, v. 35, n. 41, p. 13853, doi. 10.1523/JNEUROSCI.2600-15.2015

By:

Lindberg, Iris;
Shorter, James;
Luke Wiseman, R.;
Chiti, Fabrizio;
Dickey, Chad A.;
McLean, Pamela J.

Publication type:

Article

CRISPR/Cas9 editing of APP C-terminus attenuates β-cleavage and promotes α-cleavage.

Published in:

Nature Communications, 2019, v. 10, n. 1, p. 1, doi. 10.1038/s41467-018-07971-8

By:

Sun, Jichao;
Carlson-Stevermer, Jared;
Das, Utpal;
Shen, Minjie;
Delenclos, Marion;
Snead, Amanda M.;
Koo, So Yeon;
Wang, Lina;
Qiao, Dianhua;
Loi, Jonathan;
Petersen, Andrew J.;
Stockton, Michael;
Bhattacharyya, Anita;
Jones, Mathew V.;
Zhao, Xinyu;
McLean, Pamela J.;
Sproul, Andrew A.;
Saha, Krishanu;
Roy, Subhojit

Publication type:

Article

Convergence of pathology in dementia with Lewy bodies and Alzheimer's disease: a role for the novel interaction of alpha-synuclein and presenilin 1 in disease.

Published in:

2014

By:

Winslow, Ashley R;
Moussaud, Simon;
Zhu, Liya;
Post, Katherine L;
Dickson, Dennis W;
Berezovska, Oksana;
McLean, Pamela J;
Post, Kathryn L

Publication type:

journal article

Convergence of pathology in dementia with Lewy bodies and Alzheimer’s disease: a role for the novel interaction of alpha-synuclein and presenilin 1 in disease.

Published in:

Brain: A Journal of Neurology, 2014, v. 137, n. 7, p. 1958, doi. 10.1093/brain/awu119

By:

Winslow, Ashley R.;
Moussaud, Simon;
Zhu, Liya;
Post, Katherine L.;
Dickson, Dennis W.;
Berezovska, Oksana;
McLean, Pamela J.

Publication type:

Article

Molecular Chaperones and Co-Chaperones in Parkinson Disease.

Published in:

Neuroscientist, 2012, v. 18, n. 6, p. 589, doi. 10.1177/1073858412441372

By:

Dimant, Hemi;
Ebrahimi-Fakhari, Darius;
McLean, Pamela J.

Publication type:

Article

Role of gut microbiota in regulating gastrointestinal dysfunction and motor symptoms in a mouse model of Parkinson’s disease.

Published in:

Gut Microbes, 2021, v. 13, n. 1, p. 1, doi. 10.1080/19490976.2020.1866974

By:

Bhattarai, Yogesh;
Si, Jie;
Pu, Meng;
Ross, Owen A.;
McLean, Pamela J.;
Till, Lisa;
Moor, William;
Grover, Madhusudan;
Kandimalla, Karunya K.;
Margolis, Kara G.;
Farrugia, Gianrico;
Kashyap, Purna C.

Publication type:

Article

Alpha-synuclein has an altered conformation and shows a tight intermolecular interaction with ubiquitin in Lewy bodies.

Published in:

Acta Neuropathologica, 2001, v. 102, n. 4, p. 329, doi. 10.1007/s004010100369

By:

Sharma, Nutan;
McLean, Pamela J.;
Kawamata, Hibiki;
Irizarry, Michael C.;
Hyman, Bradley T.

Publication type:

Article

Secretome from iPSC-derived MSCs exerts proangiogenic and immunosuppressive effects to alleviate radiation-induced vascular endothelial cell damage.

Published in:

Stem Cell Research & Therapy, 2024, v. 15, n. 1, p. 1, doi. 10.1186/s13287-024-03847-5

By:

Gupta, Kshama;
Perkerson III, Ralph B.;
Parsons, Tammee M.;
Angom, Ramacharan;
Amerna, Danilyn;
Burgess, Jeremy D.;
Ren, Yingxue;
McLean, Pamela J.;
Mukhopadhyay, Debabrata;
Vibhute, Prasanna;
Wszolek, Zbigniew K.;
Zubair, Abba C.;
Quiñones-Hinojosa, Alfredo;
Kanekiyo, Takahisa

Publication type:

Article

A mutant methionyl-tRNA synthetase-based toolkit to assess induced-mesenchymal stromal cell secretome in mixed-culture disease models.

Published in:

Stem Cell Research & Therapy, 2023, v. 14, n. 1, p. 1, doi. 10.1186/s13287-023-03515-0

By:

Burgess, Jeremy D.;
Amerna, Danilyn;
Norton, Emily S.;
Parsons, Tammee M.;
Perkerson III, Ralph B.;
Faroqi, Ayman H.;
Wszolek, Zbigniew K.;
Guerrero Cazares, Hugo;
Kanekiyo, Takahisa;
Delenclos, Marion;
McLean, Pamela J.

Publication type:

Article

Exosomal cell-to-cell transmission of alpha synuclein oligomers.

Published in:

Molecular Neurodegeneration, 2012, v. 7, n. 1, p. 42, doi. 10.1186/1750-1326-7-42

By:

Danzer, Karin M.;
Kranich, Lisa R.;
Ruf, Wolfgang P.;
Cagsal-Getkin, Ozge;
Winslow, Ashley R.;
Zhu, Liya;
Vanderburg, Charles R.;
McLean, Pamela J.

Publication type:

Article

Cellular models of alpha‐synuclein toxicity and aggregation.

Published in:

Journal of Neurochemistry, 2019, v. 150, n. 5, p. 566, doi. 10.1111/jnc.14806

By:

Delenclos, Marion;
Burgess, Jeremy D.;
Lamprokostopoulou, Agaristi;
Outeiro, Tiago F.;
Vekrellis, Kostas;
McLean, Pamela J.

Publication type:

Article

Direct Visualization of CHIP-Mediated Degradation of Alpha-Synuclein <i>In Vivo</i>: Implications for PD Therapeutics.

Published in:

PLoS ONE, 2014, v. 9, n. 3, p. 1, doi. 10.1371/journal.pone.0092098

By:

Dimant, Hemi;
Zhu, Liya;
Kibuuka, Laura N.;
Fan, Zhanyun;
Hyman, Bradley T.;
McLean, Pamela J.

Publication type:

Article

Chronic Treatment with Novel Small Molecule Hsp90 Inhibitors Rescues Striatal Dopamine Levels but Not α-Synuclein-Induced Neuronal Cell Loss.

Published in:

PLoS ONE, 2014, v. 9, n. 1, p. 1, doi. 10.1371/journal.pone.0086048

By:

McFarland, Nikolaus R.;
Dimant, Hemi;
Kibuuka, Laura;
Ebrahimi-Fakhari, Darius;
Desjardins, Cody A.;
Danzer, Karin M.;
Danzer, Michael;
Fan, Zhanyun;
Schwarzschild, Michael A.;
Hirst, Warren;
McLean, Pamela J.

Publication type:

Article

Ubiquitinylation of α-Synuclein by Carboxyl Terminus Hsp70-Interacting Protein (CHIP) Is Regulated by Bcl-2-Associated Athanogene 5 (BAG5).

Published in:

PLoS ONE, 2011, v. 6, n. 2, p. 1, doi. 10.1371/journal.pone.0014695

By:

Kalia, Lorraine V.;
Kalia, Suneil K.;
Chau, Hien;
Lozano, Andres M.;
Hyman, Bradley T.;
McLean, Pamela J.

Publication type:

Article

In Vivo Imaging of α-Synuclein in Mouse Cortex Demonstrates Stable Expression and Differential Subcellular Compartment Mobility.

Published in:

PLoS ONE, 2010, v. 5, n. 5, p. 1, doi. 10.1371/journal.pone.0010589

By:

Unni, Vivek K.;
Weissman, Tamily A.;
Rockenstein, Edward;
Masliah, Eliezer;
McLean, Pamela J.;
Hyman, Bradley T.

Publication type:

Article

Dopamine-Induced Conformational Changes in Alpha-Synuclein.

Published in:

PLoS ONE, 2009, v. 4, n. 9, p. 1, doi. 10.1371/journal.pone.0006906

By:

Outeiro, Tiago F.;
Klucken, Jochen;
Bercury, Kathryn;
Tetzlaff, Julie;
Putcha, Preeti;
Oliveira, Luis M. A.;
Quintas, Alexandre;
McLean, Pamela J.;
Hyman, Bradley T.

Publication type:

Article

Formation of Toxic Oligomeric α-Synuclein Species in Living Cells.

Published in:

PLoS ONE, 2008, v. 3, n. 4, p. 1, doi. 10.1371/journal.pone.0001867

By:

Outeiro, Tiago Fleming;
Putcha, Preeti;
Tetzlaff, Julie E.;
Spoelgen, Robert;
Koker, Mirjam;
Carvalho, Filipe;
Hyman, Bradley T.;
McLean, Pamela J.

Publication type:

Article

Investigation of Endocytic Pathways for the Internalization of Exosome-Associated Oligomeric Alpha-Synuclein.

Published in:

Frontiers in Neuroscience, 2017, v. 11, p. 1, doi. 10.3389/fnins.2017.00172

By:

Delenclos, Marion;
Trendafilova, Teodora;
Mahesh, Divya;
Baine, Ann M.;
Moussaud, Simon;
Yan, Irene K.;
Patel, Tushar;
McLean, Pamela J.

Publication type:

Article

SIRT1 Protects against α-Synuclein Aggregation by Activating Molecular Chaperones.

Published in:

Journal of Neuroscience, 2012, v. 32, n. 1, p. 124, doi. 10.1523/JNEUROSCI.3442-11.2012

By:

Donmez, Gizem;
Arun, Anirudh;
Chee-Yeun Chung;
McLean, Pamela J.;
Lindquist, Susan;
Guarente, Leonard

Publication type:

Article

Distinct Roles In Vivo for the Ubiquitin-Proteasome System and the Autophagy-Lysosomal Pathway in the Degradation of α-Synuclein.

Published in:

Journal of Neuroscience, 2011, v. 31, n. 41, p. 14508, doi. 10.1523/JNEUROSCI.1560-11.2011

By:

Ebrahimi-Fakhari, Darius;
Cantuti-Castelvetri, Ippolita;
Fan, Zhanyun;
Rockenstein, Edward;
Masliah, Eliezer;
Hyman, Bradley T.;
McLean, Pamela J.;
Unni, Vivek K.

Publication type:

Article

Lewy body dementia: Overcoming barriers and identifying solutions.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2024, v. 20, n. 3, p. 2298, doi. 10.1002/alz.13674

By:

Agarwal, Kanishka;
Backler, Wendi;
Bayram, Ece;
Bloom, Leah;
Boeve, Bradley F.;
Cha, Jang‐Ho;
Denslow, Maria;
Ferman, Tanis J.;
Galasko, Douglas;
Galvin, James E.;
Gomperts, Stephen N.;
Irizarry, Michael C.;
Kantarci, Kejal;
Kaushik, Harsh;
Kietlinski, Matt;
Koenig, Aaron;
Leverenz, James B.;
McKeith, Ian;
McLean, Pamela J.;
Montine, Thomas J.

Publication type:

Article

Post‐inflammatory administration of N‐acetylcysteine reduces inflammation and alters receptor levels in a cellular model of Parkinson's disease.

Published in:

FASEB Bioadvances, 2023, v. 5, n. 7, p. 263, doi. 10.1096/fba.2022-00145

By:

Kaya, Zeynep Bengisu;
Karakoc, Elif;
McLean, Pamela J.;
Saka, Esen;
Atilla, Pergin

Publication type:

Article

A Rapid, Semi-Quantitative Assay to Screen for Modulators of Alpha-Synuclein Oligomerization Ex vivo.

Published in:

Frontiers in Neuroscience, 2016, p. 1, doi. 10.3389/fnins.2015.00511

By:

Delenclos, Marion;
Trendafilova, Teodora;
Jones, Daryl R.;
Moussaud, Simon;
Baine, Ann-Marie;
Mei Yue;
Hirst, Warren D.;
McLean, Pamela J.

Publication type:

Article

A rapid, semi-quantitative assay to screen for modulators of alpha-synuclein oligomerization ex vivo.

Published in:

Frontiers in Neuroscience, 2015, p. 1, doi. 10.3389/fnins.2015.00511

By:

Delenclos, Marion;
Trendafilova, Teodora;
Jones, Daryl R.;
Moussaud, Simon;
Baine, Ann Marie;
Mei Yue;
Hirst, Warren D.;
McLean, Pamela J.

Publication type:

Article

Alpha-synuclein aggregation involves a bafilomycin A<sub>1</sub>-sensitive autophagy pathway.

Published in:

Autophagy, 2012, v. 8, n. 5, p. 754, doi. 10.4161/auto.19371

By:

Klucken, Jochen;
Poehler, Anne-Maria;
Ebrahimi-Fakhari, Darius;
Schneider, Jacqueline;
Nuber, Silke;
Rockenstein, Edward;
Schlötzer-Schrehardt, Ursula;
Hyman, Bradley T.;
McLean, Pamela J.;
Masliah, Eliezer;
Winkler, Juergen

Publication type:

Article

Alpha-synuclein's degradation in vivo.

Published in:

Autophagy, 2012, v. 8, n. 2, p. 281, doi. 10.4161/auto.8.2.18938

By:

Ebrahimi-Fakhari, Darius;
McLean, Pamela J.;
Unni, Vivek K.

Publication type:

Article

Alpha-synuclein-induced mitochondrial dysfunction is mediated via a sirtuin 3-dependent pathway.

Published in:

Molecular Neurodegeneration, 2020, v. 15, n. 1, p. 1, doi. 10.1186/s13024-019-0349-x

By:

Park, Jae-Hyeon;
Burgess, Jeremy D.;
Faroqi, Ayman H.;
DeMeo, Natasha N.;
Fiesel, Fabienne C.;
Springer, Wolfdieter;
Delenclos, Marion;
McLean, Pamela J.

Publication type:

Article

α-synuclein interacts with SOD1 and promotes its oligomerization.

Published in:

Molecular Neurodegeneration, 2015, v. 10, p. 1, doi. 10.1186/s13024-015-0062-3

By:

Helferich, Anika M.;
Ruf, Wolfgang P.;
Grozdanov, Veselin;
Freischmidt, Axel;
Feiler, Marisa S.;
Zondler, Lisa;
Ludolph, Albert C.;
McLean, Pamela J.;
Weishaupt, Jochen H.;
Danzer, Karin M.

Publication type:

Article

Distinct transcriptional alterations distinguish Lewy body disease from Alzheimer's disease.

Published in:

Brain: A Journal of Neurology, 2025, v. 148, n. 1, p. 69, doi. 10.1093/brain/awae202

By:

Olney, Kimberly C;
Rabichow, Benjamin E;
Wojtas, Aleksandra M;
DeTure, Michael;
McLean, Pamela J;
Dickson, Dennis W;
Chang, Rui;
Ross, Owen A;
Fryer, John D

Publication type:

Article

Comparison of transduction efficiency of recombinant AAV serotypes 1, 2, 5, and 8 in the rat nigrostriatal system.

Published in:

Journal of Neurochemistry, 2009, v. 109, n. 3, p. 838, doi. 10.1111/j.1471-4159.2009.06010.x

By:

McFarland, Nikolaus R.;
Jeng-Shin Lee;
Hyman, Bradley T.;
McLean, Pamela J.

Publication type:

Article

Dopaminergic neuron loss and up-regulation of chaperone protein mRNA induced by targeted over-expression of alpha-synuclein in mouse substantia nigra.

Published in:

Journal of Neurochemistry, 2007, v. 100, n. 6, p. 1449, doi. 10.1111/j.1471-4159.2006.04310.x

By:

St Martin, Jessie L.;
Klucken, Jochen;
Outeiro, Tiago F.;
Nguyen, Paul;
Keller-McGandy, Christine;
Cantuti-Castelvetri, Ippolita;
Grammatopoulos, Tom N.;
Standaert, David G.;
Hyman, Bradley T.;
McLean, Pamela J.

Publication type:

Article

Interaction of α-synuclein and synphilin-1: effect of Parkinson's disease-associated mutations.

Published in:

Journal of Neurochemistry, 2001, v. 77, n. 3, p. 929, doi. 10.1046/j.1471-4159.2001.00301.x

By:

Kawamata, Hibiki;
McLean, Pamela J.;
Sharma, Nutan;
Hyman, Bradley T.

Publication type:

Article