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Novel histone modifications in microglia derived from a mouse model of chronic pain.
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- Proteomics, 2022, v. 22, n. 9, p. 1, doi. 10.1002/pmic.202100137
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- Publication type:
- Article
In vivo proton magnetic resonance spectroscopy detection of metabolite abnormalities in aged Tat-transgenic mouse brain.
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- GeroScience, 2021, v. 43, n. 4, p. 1851, doi. 10.1007/s11357-021-00354-w
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- Article
Sleep Disorder and Cocaine Abuse Impact Purine and Pyrimidine Nucleotide Metabolic Signatures.
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- Metabolites (2218-1989), 2022, v. 12, n. 9, p. 869, doi. 10.3390/metabo12090869
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- Article
Epigenetic signature of N-terminal acetyltransferases: a probable mediator of immune and neuropathogenesis in HIV infection.
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- Molecular Brain, 2022, v. 15, n. 1, p. 1, doi. 10.1186/s13041-022-00946-3
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- Article
Endogenous κ Opioid Activation Mediates Stress-Induced Deficits in Learning and Memory.
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- Journal of Neuroscience, 2009, v. 29, n. 13, p. 4293, doi. 10.1523/JNEUROSCI.6146-08.2009
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- Article
Neuropathic Pain Activates the Endogenous κ Opioid System in Mouse Spinal Cord and Induces Opioid Receptor Tolerance.
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- Journal of Neuroscience, 2004, v. 24, n. 19, p. 4576, doi. 10.1523/JNEUROSCI.5552-03.2004
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- Article
Discovery of a Highly Selective Sigma-2 Receptor Ligand, 1-(4-(6,7-Dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)butyl)-3-methyl-1H-benzo[d]imidazol-2(3H)-one (CM398), with Drug-Like Properties and Antinociceptive Effects In Vivo.
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- AAPS Journal, 2020, v. 22, n. 5, p. N.PAG, doi. 10.1208/s12248-020-00472-x
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- Article
Peptides derived from the prohormone proNPQ/spexin are potent central modulators of cardiovascular and renal function and nociception.
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- FASEB Journal, 2012, v. 26, n. 2, p. 947, doi. 10.1096/fj.11-192831
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- Article
Identification and Pharmacological Characterization of a Low-Liability Antinociceptive Bifunctional MOR/DOR Cyclic Peptide.
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- Molecules, 2023, v. 28, n. 22, p. 7548, doi. 10.3390/molecules28227548
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- Article
Solid-Phase Synthesis of the Bicyclic Peptide OL-CTOP Containing Two Disulfide Bridges, and an Assessment of Its In Vivo μ-Opioid Receptor Antagonism after Nasal Administration.
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- Molecules, 2023, v. 28, n. 4, p. 1822, doi. 10.3390/molecules28041822
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- Publication type:
- Article
Characterization of CM-398, a Novel Selective Sigma-2 Receptor Ligand, as a Potential Therapeutic for Neuropathic Pain.
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- Molecules, 2022, v. 27, n. 11, p. 3617, doi. 10.3390/molecules27113617
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- Publication type:
- Article
Phenylalanine Stereoisomers of CJ-15,208 and [d-Trp]CJ-15,208 Exhibit Distinctly Different Opioid Activity Profiles.
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- Molecules, 2020, v. 25, n. 17, p. 3999, doi. 10.3390/molecules25173999
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- Article
Proteomics Profiling with SWATH-MS Quantitative Analysis of Changes in the Human Brain with HIV Infection Reveals a Differential Impact on the Frontal and Temporal Lobes.
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- Brain Sciences (2076-3425), 2021, v. 11, n. 11, p. 1438, doi. 10.3390/brainsci11111438
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- Article
Expression of Human Immunodeficiency Virus Transactivator of Transcription (HIV-Tat<sub>1-86</sub>) Protein Alters Nociceptive Processing that is Sensitive to Anti-Oxidant and Anti-Inflammatory Interventions.
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- Journal of NeuroImmune Pharmacology, 2022, v. 17, n. 1/2, p. 152, doi. 10.1007/s11481-021-09985-4
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- Article
Effects of Conditional Central Expression of HIV-1 Tat Protein to Potentiate Cocaine-Mediated Psychostimulation and Reward Among Male Mice.
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- Neuropsychopharmacology, 2014, v. 39, n. 2, p. 380, doi. 10.1038/npp.2013.201
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- Article
Partial Opioids: Medications for the Treatment of Pain and Drug Abuse.
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- Annals of the New York Academy of Sciences, 2000, v. 909, n. 1, p. 1, doi. 10.1111/j.1749-6632.2000.tb06672.x
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- Article
Controlling opioid receptor functional selectivity by targeting distinct subpockets of the orthosteric site.
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- eLife, 2021, p. 1, doi. 10.7554/eLife.56519
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- Article
Endogenous kappa-opioid mediation of stress-induced potentiation of ethanol-conditioned place preference and self-administration.
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- Psychopharmacology, 2010, v. 210, n. 2, p. 199, doi. 10.1007/s00213-010-1844-5
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- Article
Multifunctional opioid receptor agonism and antagonism by a novel macrocyclic tetrapeptide prevents reinstatement of morphine-seeking behaviour.
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- 2020
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- Publication type:
- journal article
Characterization of Sigma 1 Receptor Antagonist CM-304 and Its Analog, AZ-66: Novel Therapeutics Against Allodynia and Induced Pain.
- Published in:
- Frontiers in Pharmacology, 2019, p. N.PAG, doi. 10.3389/fphar.2019.00678
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- Article
HIV‐1 Tat regulation of dopamine transmission and microglial reactivity is brain region specific.
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- Glia, 2018, v. 66, n. 9, p. 1915, doi. 10.1002/glia.23447
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- Article
Something to talk about; crosstalk disruption at the neurovascular unit during HIV infection of the CNS.
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- NeuroImmune Pharmacology & Therapeutics, 2024, v. 3, n. 2, p. 97, doi. 10.1515/nipt-2024-0003
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- Publication type:
- Article
SRI-30827, a novel allosteric modulator of the dopamine transporter, alleviates HIV-1 Tat-induced potentiation of cocaine conditioned place preference in mice.
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- NeuroImmune Pharmacology & Therapeutics, 2024, v. 3, n. 1, p. 1, doi. 10.1515/nipt-2023-0022
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- Article
Clathrin-nanoparticles deliver BDNF to hippocampus and enhance neurogenesis, synaptogenesis and cognition in HIV/neuroAIDS mouse model.
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- Communications Biology, 2022, v. 5, n. 1, p. 1, doi. 10.1038/s42003-022-03177-3
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- Article
The cross-talk of HIV-1 Tat and methamphetamine in HIV-associated neurocognitive disorders.
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- Frontiers in Microbiology, 2015, v. 6, p. 1, doi. 10.3389/fmicb.2015.01164
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- Article
Unexpected Opioid Activity Profiles of Analogues of the Novel Peptide Kappa Opioid Receptor Ligand CJ-15,208.
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- ChemMedChem, 2011, v. 6, n. 9, p. 1739, doi. 10.1002/cmdc.201100113
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- Article
Social Defeat Stress-Induced Behavioral Responses are Mediated by the Endogenous Kappa Opioid System.
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- Neuropsychopharmacology, 2006, v. 31, n. 6, p. 1241, doi. 10.1038/sj.npp.1300872
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- Article
Prior Activation of Kappa Opioid Receptors by U50,488 Mimics Repeated Forced Swim Stress to Potentiate Cocaine Place Preference Conditioning.
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- Neuropsychopharmacology, 2006, v. 31, n. 4, p. 787, doi. 10.1038/sj.npp.1300860
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- Article
κ Opioid Receptor Antagonism and Prodynorphin Gene Disruption Block Stress-Induced Behavioral Responses.
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- Journal of Neuroscience, 2003, v. 23, n. 13, p. 5674, doi. 10.1523/JNEUROSCI.23-13-05674.2003
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- Publication type:
- Article
HIV-Tat and Cocaine Impact Brain Energy Metabolism: Redox Modification and Mitochondrial Biogenesis Influence NRF Transcription-Mediated Neurodegeneration.
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- Molecular Neurobiology, 2021, v. 58, n. 2, p. 490, doi. 10.1007/s12035-020-02131-w
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- Article
Selective κ receptor partial agonist HS666 produces potent antinociception without inducing aversion after i.c.v. administration in mice.
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- 2017
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- Publication type:
- journal article
The macrocyclic tetrapeptide [D-Trp]CJ-15,208 produces short-acting κ opioid receptor antagonism in the CNS after oral administration.
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- 2013
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- Publication type:
- journal article
The macrocyclic tetrapeptide [ D- Trp] CJ-15,208 produces short-acting κ opioid receptor antagonism in the CNS after oral administration.
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- British Journal of Pharmacology, 2013, v. 169, n. 2, p. 426, doi. 10.1111/bph.12132
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- Publication type:
- Article
Novel opioid cyclic tetrapeptides: Trp isomers of CJ-15,208 exhibit distinct opioid receptor agonism and short-acting κ opioid receptor antagonism.
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- British Journal of Pharmacology, 2012, v. 165, n. 4b, p. 1097, doi. 10.1111/j.1476-5381.2011.01544.x
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- Publication type:
- Article
Novel opioid cyclic tetrapeptides: Trp isomers of CJ-15,208 exhibit distinct opioid receptor agonism and short-acting κ opioid receptor antagonism.
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- 2012
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- Publication type:
- journal article
Tryptophan Substitution in CJ-15,208 (cyclo [Phe-D-Pro-Phe-Trp]) Introduces δ-Opioid Receptor Antagonism, Preventing Antinociceptive Tolerance and Stress-Induced Reinstatement of Extinguished Cocaine-Conditioned Place Preference.
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- Pharmaceuticals (14248247), 2023, v. 16, n. 9, p. 1218, doi. 10.3390/ph16091218
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- Article
Kratom Alkaloids, Natural and Semi-Synthetic, Show Less Physical Dependence and Ameliorate Opioid Withdrawal.
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- Cellular & Molecular Neurobiology, 2021, v. 41, n. 5, p. 1131, doi. 10.1007/s10571-020-01034-7
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- Publication type:
- Article
Bis-Cyclic Guanidine Heterocyclic Peptidomimetics as Opioid Ligands with Mixed μ-, κ- and δ-Opioid Receptor Interactions: A Potential Approach to Novel Analgesics.
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- International Journal of Molecular Sciences, 2022, v. 23, n. 17, p. 9623, doi. 10.3390/ijms23179623
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- Article
Examination of the Novel Sigma-1 Receptor Antagonist, SI 1/28, for Antinociceptive and Anti-allodynic Efficacy against Multiple Types of Nociception with Fewer Liabilities of Use.
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- International Journal of Molecular Sciences, 2022, v. 23, n. 2, p. 615, doi. 10.3390/ijms23020615
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- Article