Works matching AU McKnight, Amy Jayne

Results: 64

Polygenic risk scores for eGFR are associated with age at kidney failure.

Published in:

Journal of Nephrology (JNonline), 2025, v. 38, n. 3, p. 969, doi. 10.1007/s40620-025-02207-7

By:

Collins, Kane E.;
Gilbert, Edmund;
Mauduit, Vincent;
Gaheer, Pukhraj;
Elhassan, Elhussein A. E.;
Benson, Katherine A.;
Osman, Shohdan Mohamad;
Hill, Claire;
McKnight, Amy Jayne;
Maxwell, Alexander Peter;
van der Most, Peter J.;
de Borst, Martin H.;
Guan, Weihua;
Jacobson, Pamala A.;
Israni, Ajay K.;
Keating, Brendan J.;
Lord, Graham M.;
Markkinen, Salla;
Helanterä, Ilkka;
Hyvärinen, Kati

Publication type:

Article

Research recommendations from the 2024 Breakthrough T1D, Diabetes UK and Kidney Research UK, diabetes and kidney disease expert workshop.

Published in:

Diabetic Medicine, 2025, v. 42, n. 7, p. 1, doi. 10.1111/dme.70013

By:

Markham‐Lee, Zoe;
Bhagat‐Jones, Swati;
Carlton, Jill;
Frankel, Andrew;
Fraser, Simon;
Habte‐Asres, Hellena H.;
Hill, Claire;
Kanumilli, Naresh;
Karalliedde, Janaka;
Maskell, Annelie;
McKnight, Amy Jayne;
Morris, Anna;
Nitsch, Dorothea;
Otake John, Nia;
Parks, Steven;
Robinson, Sarah Jane;
Rosenthal, Miranda;
Rutter, Martin K.;
Schmutz, Caroline;
Scullion, Shawna

Publication type:

Article

When should we offer antenatal sequencing for urinary tract malformations? A systematic review, cohort study and meta‐analysis.

Published in:

Prenatal Diagnosis, 2024, v. 44, n. 2, p. 187, doi. 10.1002/pd.6479

By:

Sonner, Sarah;
Reilly, Kelly;
Woolf, Adrian S.;
Chandler, Natalie;
Kilby, Mark D.;
Maher, Eamonn R.;
Flanagan, Cheryl;
McKnight, Amy Jayne;
Mone, Fionnuala

Publication type:

Article

Annotated chromosome maps for renal disease.

Published in:

2009

By:

McKnight, Amy Jayne;
O'Donoghue, Donal;
Peter Maxwell, A.

Publication type:

Other

Integrated multiomic analyses: An approach to improve understanding of diabetic kidney disease.

Published in:

Diabetic Medicine, 2025, v. 42, n. 2, p. 1, doi. 10.1111/dme.15447

By:

Hill, Claire;
McKnight, Amy Jayne;
Smyth, Laura J.

Publication type:

Article

Genetic and Epigenetic Associations with Post-Transplant Diabetes Mellitus.

Published in:

Genes, 2024, v. 15, n. 4, p. 503, doi. 10.3390/genes15040503

By:

Abdelrahman, Zeinab;
Maxwell, Alexander Peter;
McKnight, Amy Jayne

Publication type:

Article

Differential Methylation of Telomere-Related Genes Is Associated with Kidney Disease in Individuals with Type 1 Diabetes.

Published in:

Genes, 2023, v. 14, n. 5, p. 1029, doi. 10.3390/genes14051029

By:

Hill, Claire;
Duffy, Seamus;
Kettyle, Laura M.;
McGlynn, Liane;
Sandholm, Niina;
Salem, Rany M.;
Thompson, Alex;
Swan, Elizabeth J.;
Kilner, Jill;
Rossing, Peter;
Shiels, Paul G.;
Lajer, Maria;
Groop, Per-Henrik;
Maxwell, Alexander Peter;
McKnight, Amy Jayne

Publication type:

Article

Harnessing Genomic Analysis to Explore the Role of Telomeres in the Pathogenesis and Progression of Diabetic Kidney Disease.

Published in:

Genes, 2023, v. 14, n. 3, p. 609, doi. 10.3390/genes14030609

By:

Hill, Claire;
Duffy, Seamus;
Coulter, Tiernan;
Maxwell, Alexander Peter;
McKnight, Amy Jayne

Publication type:

Article

A Formative Study of the Implementation of Whole Genome Sequencing in Northern Ireland.

Published in:

Genes, 2022, v. 13, n. 7, p. 1104, doi. 10.3390/genes13071104

By:

Kerr, Katie;
McKenna, Caoimhe;
Heggarty, Shirley;
Bailie, Caitlin;
McMullan, Julie;
Crowe, Ashleen;
Kilner, Jill;
Donnelly, Michael;
Boyle, Saralynne;
Rea, Gillian;
Flanagan, Cheryl;
McKee, Shane;
McKnight, Amy Jayne

Publication type:

Article

Validation of differentially methylated microRNAs identified from an epigenome‑wide association study; Sanger and next generation sequencing approaches.

Published in:

BMC Research Notes, 2018, v. 11, n. 1, p. 1, doi. 10.1186/s13104-018-3872-x

By:

Smyth, Laura J.;
Maxwell, Alexander P.;
Benson, Katherine A.;
Kilner, Jill;
McKay, Gareth J.;
McKnight, Amy Jayne

Publication type:

Article

Caveolin-1 Single Nucleotide Polymorphism in Antineutrophil Cytoplasmic Antibody Associated Vasculitis.

Published in:

PLoS ONE, 2013, v. 8, n. 7, p. 1, doi. 10.1371/journal.pone.0069022

By:

Chand, Sourabh;
Holle, Julia U.;
Hilhorst, Marc;
Simmonds, Matthew J.;
Smith, Stuart;
Kamesh, Lavanya;
Hewins, Peter;
McKnight, Amy Jayne;
Maxwell, Alexander P.;
Cohen Tervaert, Jan Willem;
Wieczorek, Stefan;
Harper, Lorraine;
Borrows, Richard

Publication type:

Article

Comprehensive Investigation of the Caveolin 2 Gene: Resequencing and Association for Kidney Transplant Outcomes

Published in:

PLoS ONE, 2013, v. 8, n. 5, p. 1, doi. 10.1371/journal.pone.0063358

By:

McCaughan, Jennifer A.;
Duffy, Seamus;
O'Hagan, Thomas;
Courtney, Aisling E.;
Borrows, Richard;
Conlon, Peter J.;
Maxwell, Alexander P.;
McKnight, Amy Jayne

Publication type:

Article

Association Analysis of Dyslipidemia-Related Genes in Diabetic Nephropathy.

Published in:

PLoS ONE, 2013, v. 8, n. 3, p. 1, doi. 10.1371/journal.pone.0058472

By:

McKay, Gareth J.;
Savage, David A.;
Patterson, Christopher C.;
Lewis, Gareth;
McKnight, Amy Jayne;
Maxwell, Alexander P.

Publication type:

Article

Association Analysis of Canonical Wnt Signalling Genes in Diabetic Nephropathy.

Published in:

PLoS ONE, 2011, v. 6, n. 8, p. 1, doi. 10.1371/journal.pone.0023904

By:

Kavanagh, David H.;
Savage, David A.;
Patterson, Christopher C.;
McKnight, Amy Jayne;
Crean, John K.;
Maxwell, Alexander P.;
McKay, Gareth J.

Publication type:

Article

Genome-wide association meta-analysis for early age-related macular degeneration highlights novel loci and insights for advanced disease.

Published in:

BMC Medical Genomics, 2020, v. 13, n. 1, p. N.PAG, doi. 10.1186/s12920-020-00760-7

By:

Winkler, Thomas W.;
Grassmann, Felix;
Brandl, Caroline;
Kiel, Christina;
Günther, Felix;
Strunz, Tobias;
Weidner, Lorraine;
Zimmermann, Martina E.;
Korb, Christina A.;
Poplawski, Alicia;
Schuster, Alexander K.;
Müller-Nurasyid, Martina;
Peters, Annette;
Rauscher, Franziska G.;
Elze, Tobias;
Horn, Katrin;
Scholz, Markus;
Cañadas-Garre, Marisa;
McKnight, Amy Jayne;
Quinn, Nicola

Publication type:

Article

A quick reference guide for rare disease: supporting rare disease management in general practice.

Published in:

2020

By:

Crowe, Ashleen;
McAneney, Helen;
Morrison, Patrick J;
Cupples, Margaret E;
McKnight, Amy Jayne

Publication type:

journal article

Donor and Recipient Polygenic Risk Scores Influence Kidney Transplant Function.

Published in:

Transplant International, 2025, p. 1, doi. 10.3389/ti.2025.14171

By:

Collins, Kane E.;
Gilbert, Edmund;
Mauduit, Vincent;
Benson, Katherine A.;
Elhassan, Elhussein A. E.;
O'Seaghdha, Conall;
Hill, Claire;
McKnight, Amy Jayne;
Maxwell, Alexander P.;
van der Most, Peter J.;
de Borst, Martin H.;
Guan, Weihua;
Jacobson, Pamala A.;
Israni, Ajay K.;
Keating, Brendan J.;
Lord, Graham M.;
Markkinen, Salla;
Helanterä, Ilkka;
Hyvärinen, Kati;
Partanen, Jukka

Publication type:

Article

Stakeholder Perceptions of Complementary and Integrative Medicines from People Living with Rare Diseases in Northern Ireland: A Mixed Methods Study.

Published in:

Complementary Medicine Research, 2024, v. 31, n. 2, p. 107, doi. 10.1159/000535480

By:

Crowe, Ashleen Laura;
Kerr, Katie;
McAneney, Helen;
McMullan, Julie;
Duffy, Gavin;
McKnight, Amy Jayne

Publication type:

Article

Resequencing of the CCL5 and CCR5 genes and investigation of variants for association with diabetic nephropathy.

Published in:

Journal of Human Genetics, 2010, v. 55, n. 4, p. 248, doi. 10.1038/jhg.2010.15

By:

Pettigrew, Kerry A.;
McKnight, Amy Jayne;
Patterson, Christopher C.;
Kilner, Jill;
Sadlier, Denise M.;
Maxwell, Alexander P.

Publication type:

Article

Association of microsatellite markers on chromosomes 6q27 region and 10p15 region with end-stage renal disease in a UK renal transplant population.

Published in:

Journal of Human Genetics, 2009, v. 54, n. 8, p. 497, doi. 10.1038/jhg.2009.53

By:

Currie, Diane;
McKnight, Amy Jayne;
Patterson, Christopher C.;
Martin, Rosalind J. L.;
Middleton, Derek;
Courtney, Aisling E.;
Maxwell, Alexander P.

Publication type:

Article

Resequencing of the characterised CTGF gene to identify novel or known variants, and analysis of their association with diabetic nephropathy.

Published in:

Journal of Human Genetics, 2006, v. 51, n. 4, p. 383, doi. 10.1007/s10038-006-0368-7

By:

McKnight, Amy Jayne;
Savage, David A.;
Patterson, Chris C.;
Brady, Hugh R.;
Maxwell, A. Peter

Publication type:

Article

Evaluating the impact of COVID-19 on rare disease support groups.

Published in:

BMC Research Notes, 2021, v. 14, n. 1, p. 1, doi. 10.1186/s13104-021-05579-8

By:

McMullan, Julie;
Crowe, Ashleen L.;
Bailie, Caitlin;
McKnight, Amy Jayne

Publication type:

Article

Contribution of cystatin C- and creatinine-based definitions of chronic kidney disease to cardiovascular risk assessment in 20 population-based and 3 disease cohorts: the BiomarCaRE project.

Published in:

2020

By:

Rothenbacher, Dietrich;
Rehm, Martin;
Iacoviello, Licia;
Costanzo, Simona;
Tunstall-Pedoe, Hugh;
Belch, Jill J. F.;
Söderberg, Stefan;
Hultdin, Johan;
Salomaa, Veikko;
Jousilahti, Pekka;
Linneberg, Allan;
Sans, Susana;
Padró, Teresa;
Thorand, Barbara;
Meisinger, Christa;
Kee, Frank;
McKnight, Amy Jayne;
Palosaari, Tarja;
Kuulasmaa, Kari;
Waldeyer, Christoph

Publication type:

journal article

Exploring the epigenome to identify biological links between the urban environment and neurodegenerative disease: an evidence review.

Published in:

Cities & Health, 2024, v. 8, n. 6, p. 1153, doi. 10.1080/23748834.2024.2335707

By:

Glover, Sophie;
Hill, Claire;
McGuinness, Bernadette;
McKnight, Amy Jayne;
Hunter, Ruth F.

Publication type:

Article

Next-generation sequencing of the mitochondrial genome and association with IgA nephropathy in a renal transplant population.

Published in:

Scientific Reports, 2014, p. 1, doi. 10.1038/srep07379

By:

Douglas, Adam P.;
Vance, Dwaine R.;
Kenny, Elaine M.;
Morris, Derek W.;
Maxwell, Alexander P.;
McKnight, Amy Jayne

Publication type:

Article

Development of next generation sequencing panel for UMOD and association with kidney disease.

Published in:

PLoS ONE, 2017, v. 12, n. 6, p. 1, doi. 10.1371/journal.pone.0178321

By:

Bailie, Caitlin;
Kilner, Jill;
Maxwell, Alexander P.;
McKnight, Amy Jayne

Publication type:

Article

<i>CD2AP</i> is associated with end-stage renal disease in patients with type 1 diabetes.

Published in:

Acta Diabetologica, 2013, v. 50, n. 6, p. 887, doi. 10.1007/s00592-013-0475-9

By:

Hyvönen, Mervi E.;
Ihalmo, Pekka;
Sandholm, Niina;
Stavarachi, Monica;
Forsblom, Carol;
McKnight, Amy Jayne;
Lajer, Maria;
Maestroni, Anna;
Lewis, Gareth;
Tarnow, Lise;
Maestroni, Silvia;
Zerbini, Gianpaolo;
Parving, Hans-Henrik;
Maxwell, Alexander P.;
Groop, Per-Henrik;
Lehtonen, Sanna

Publication type:

Article

Harnessing the Full Potential of Multi-Omic Analyses to Advance the Study and Treatment of Chronic Kidney Disease.

Published in:

Frontiers in Nephrology, 2022, v. 2, p. 1, doi. 10.3389/fneph.2022.923068

By:

Hill, Claire;
Avila-Palencia, Ione;
Maxwell, Alexander Peter;
Hunter, Ruth F.;
McKnight, Amy Jayne

Publication type:

Article

Donor genetic burden for cerebrovascular risk and kidney transplant outcome.

Published in:

Journal of Nephrology (JNonline), 2024, v. 37, n. 6, p. 1643, doi. 10.1007/s40620-024-01973-0

By:

Collins, Kane E.;
Gilbert, Edmund;
Mauduit, Vincent;
Benson, Katherine A.;
Elhassan, Elhussein A. E.;
O'Seaghdha, Conall;
Hill, Claire;
McKnight, Amy Jayne;
Maxwell, Alexander P.;
van der Most, Peter J.;
de Borst, Martin H.;
Guan, Weihua;
Jacobson, Pamala A.;
Israni, Ajay K.;
Keating, Brendan J.;
Lord, Graham M.;
Markkinen, Salla;
Helanterä, Ilkka;
Hyvärinen, Kati;
Partanen, Jukka

Publication type:

Article

Association of MYH9/APOL1 with chronic kidney disease in a UK population*.

Published in:

Nephrology Dialysis Transplantation, 2012, v. 27, n. 9, p. 3660, doi. 10.1093/ndt/gfs181

By:

McKnight, Amy Jayne;
Duffy, Seamus;
Fogarty, Damian G.;
Maxwell, Alexander P.

Publication type:

Article

The coronary artery disease SNP, rs4420638, is associated with diabetic nephropathy rather than end-stage renal disease.

Published in:

2009

By:

Buckham, Theresa;
Maxwell, Alexander P.;
Courtney, Aisling E.;
McKnight, Amy Jayne

Publication type:

Letter

Genetic analysis of coronary artery disease single-nucleotide polymorphisms in diabetic nephropathy.

Published in:

Nephrology Dialysis Transplantation, 2009, v. 24, n. 8, p. 2473

By:

McKnight, Amy Jayne;
Maxwell, Alexander P.;
Fogarty, Damian G.;
Sadlier, Denise;
Savage, David A.

Publication type:

Article

Role of α-adducin DNA polymorphisms in the genetic predisposition to diabetic nephropathy.

Published in:

Nephrology Dialysis Transplantation, 2004, v. 19, n. 8, p. 2019, doi. 10.1093/ndt/gfh342

By:

Bryan R. Conway;
Rosalind Martin;
Amy-Jayne McKnight;
David A. Savage;
Hugh R. Brady;
Alexander P. Maxwell

Publication type:

Article

Genetic investigation of major histocompatibility complex class-I related RAET1 genes for association in a glomerulonephritis population.

Published in:

Nephrology Reviews, 2012, v. 4, n. 2, p. 48, doi. 10.4081/nr.2012.e11

By:

Vance, Dwaine R.;
Bennett, Theresa A.;
Maxwell, Alexander P.;
McKnight, Amy Jayne

Publication type:

Article

Review of genetic association in the SOD2 gene with chronic kidney disease: case-control studies and meta-analysis confirm association with diabetic nephropathy.

Published in:

Nephrology Reviews, 2012, v. 4, n. 2, p. 51, doi. 10.4081/nr.2012.e12

By:

McKnight, Amy Jayne;
Patterson, Christopher C.;
Möllsten, Anna;
Vance, Dwaine R.;
Tarnow, Lise;
Maxwell, Alexander P.

Publication type:

Article

A blood DNA methylation biomarker for predicting short-term risk of cardiovascular events.

Published in:

Clinical Epigenetics, 2022, v. 14, n. 1, p. 1, doi. 10.1186/s13148-022-01341-4

By:

Cappozzo, Andrea;
McCrory, Cathal;
Robinson, Oliver;
Freni Sterrantino, Anna;
Sacerdote, Carlotta;
Krogh, Vittorio;
Panico, Salvatore;
Tumino, Rosario;
Iacoviello, Licia;
Ricceri, Fulvio;
Sieri, Sabina;
Chiodini, Paolo;
McKay, Gareth J.;
McKnight, Amy Jayne;
Kee, Frank;
Young, Ian S.;
McGuinness, Bernadette;
Crimmins, Eileen M.;
Arpawong, Thalida Em;
Kenny, Rose Anne

Publication type:

Article

Haplotype association analysis of genes within the WNT signalling pathways in diabetic nephropathy.

Published in:

BMC Nephrology, 2013, v. 14, n. 1, p. 1, doi. 10.1186/1471-2369-14-126

By:

Kavanagh, David H.;
Savage, David A.;
Patterson, Christopher C.;
McKnight, Amy Jayne;
Crean, John K.;
Maxwell, Alexander P.;
McKay, Gareth J.

Publication type:

Article

Haplotype association analysis of genes within the WNT signalling pathways in diabetic nephropathy.

Published in:

2013

By:

Kavanagh, David H;
Savage, David A;
Patterson, Christopher C;
McKnight, Amy Jayne;
Crean, John K;
Maxwell, Alexander P;
McKay, Gareth J;
Warren 3/UK GoKinD Study Group

Publication type:

journal article

Genetic variants affecting mitochondrial function provide further insights for kidney disease.

Published in:

BMC Genomics, 2024, v. 25, n. 1, p. 1, doi. 10.1186/s12864-024-10449-1

By:

Cañadas-Garre, Marisa;
Baños-Jaime, Blanca;
Maqueda, Joaquín J.;
Smyth, Laura J.;
Cappa, Ruaidhri;
Skelly, Ryan;
Hill, Claire;
Brennan, Eoin P.;
Doyle, Ross;
Godson, Catherine;
Maxwell, Alexander P.;
McKnight, Amy Jayne

Publication type:

Article

Insights into the length and breadth of methodologies harnessed to study human telomeres.

Published in:

2024

By:

Coulter, Tiernan;
Hill, Claire;
McKnight, Amy Jayne

Publication type:

Editorial

Carer reported experiences: Supporting someone with a rare disease.

Published in:

Health & Social Care in the Community, 2022, v. 30, n. 3, p. 1097, doi. 10.1111/hsc.13336

By:

McMullan, Julie;
Crowe, Ashleen L.;
Downes, Kirsten;
McAneney, Helen;
McKnight, Amy Jayne

Publication type:

Article

Evaluation of Five Interleukin Genes for Association with End-Stage Renal Disease in White Europeans.

Published in:

American Journal of Nephrology, 2010, v. 32, n. 2, p. 103, doi. 10.1159/000314943

By:

Buckham, Theresa A.;
McKnight, Amy Jayne;
Benevente, David;
Courtney, Aisling E.;
Patterson, Christopher C.;
Simmonds, Matt;
Gough, Steven;
Middleton, Derek;
Borrows, Richard;
Maxwell, Alexander P.

Publication type:

Article

A HuGE Review and Meta-Analyses of Genetic Associations in New Onset Diabetes after Kidney Transplantation.

Published in:

PLoS ONE, 2016, v. 11, n. 1, p. 1, doi. 10.1371/journal.pone.0147323

By:

Benson, Katherine Angela;
Maxwell, Alexander Peter;
McKnight, Amy Jayne

Publication type:

Article

Genome-wide association study on coronary artery disease in type 1 diabetes suggests beta-defensin 127 as a risk locus.

Published in:

Cardiovascular Research, 2021, v. 117, n. 2, p. 600, doi. 10.1093/cvr/cvaa045

By:

Antikainen, Anni A V;
Sandholm, Niina;
Trégouët, David-Alexandre;
Charmet, Romain;
McKnight, Amy Jayne;
Ahluwalia, Tarunveer S;
Syreeni, Anna;
Valo, Erkka;
Forsblom, Carol;
Gordin, Daniel;
Harjutsalo, Valma;
Hadjadj, Samy;
Maxwell, Alexander P;
Rossing, Peter;
Groop, Per-Henrik

Publication type:

Article

Improvements needed to support people living and working with a rare disease in Northern Ireland: current rare disease support perceived as inadequate.

Published in:

2020

By:

McMullan, Julie;
Crowe, Ashleen L.;
Bailie, Caitlin;
Moore, Kerry;
McMullan, Lauren S.;
Shamandi, Nahid;
McAneney, Helen;
McKnight, Amy Jayne

Publication type:

journal article

A scoping review and proposed workflow for multi-omic rare disease research.

Published in:

2020

By:

Kerr, Katie;
McAneney, Helen;
Smyth, Laura J.;
Bailie, Caitlin;
McKee, Shane;
McKnight, Amy Jayne

Publication type:

journal article

Differential methylation as a diagnostic biomarker of rare renal diseases: a systematic review.

Published in:

2019

By:

Kerr, Katie;
McAneney, Helen;
Flanagan, Cheryl;
Maxwell, Alexander P.;
McKnight, Amy Jayne

Publication type:

journal article

Towards a sustainable rare disease and orphan drug ecosystem in Saudi Arabia: policy insights from a multi-stakeholder workshop.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1583477

By:

Abozaid, Ghada Mohammed;
Al-Omar, Hussain Abdulrahman;
Alrabiah, Abdulaziz;
AlMuaither, Asma;
McKnight, Amy Jayne

Publication type:

Article

Association of Caveolin-1 Gene Polymorphism With Kidney Transplant Fibrosis and Allograft Failure.

Published in:

JAMA: Journal of the American Medical Association, 2010, v. 303, n. 13, p. 1282, doi. 10.1001/jama.2010.356

By:

Moore, Jason;
McKnight, Amy Jayne;
Simmonds, Matthew J.;
Courtney, Aisling E.;
Hanvesakul, Rajesh;
Brand, Oliver J.;
Brigss, David;
Ball, Simon;
Cockwell, Paul;
Patterson, Christopher C.;
Maxwell, Alexander P.;
Gough, Stephen C. L.;
Borrows, Richard

Publication type:

Article

Association Testing of Previously Reported Variants in a Large Case-Control Meta-analysis of Diabetic Nephropathy.

Published in:

Diabetes, 2012, v. 61, n. 8, p. 2187, doi. 10.2337/db11-0751

By:

Williams, Winfred W.;
Salem, Rany M.;
Mcknight, Amy Jayne;
Sandholm, Niina;
Forsblom, Carol;
Taylor, Andrew;
Guiducci, Candace;
McAteer, Jarred B.;
McKay, Gareth J.;
Isakova, Tamara;
Brennan, Eoin P.;
Sadlier, Denise M.;
Palmer, Cameron;
Söderlund, Jenny;
Fagerholm, Emma;
Harjutsalo, Valma;
Lithovius, Raija;
Gordin, Daniel;
Hietala, Kustaa;
Kytö, Janne

Publication type:

Article