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CYP51 is an essential drug target for the treatment of primary amoebic meningoencephalitis (PAM).
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- PLoS Neglected Tropical Diseases, 2017, v. 11, n. 12, p. 1, doi. 10.1371/journal.pntd.0006104
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- Article
4-aminopyridyl-based lead compounds targeting CYP51 prevent spontaneous parasite relapse in a chronic model and improve cardiac pathology in an acute model of Trypanosoma cruzi infection.
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- PLoS Neglected Tropical Diseases, 2017, v. 11, n. 12, p. 1, doi. 10.1371/journal.pntd.0006132
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- Article
Phenotypic, chemical and functional characterization of cyclic nucleotide phosphodiesterase 4 (PDE4) as a potential anthelmintic drug target.
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- PLoS Neglected Tropical Diseases, 2017, v. 11, n. 7, p. 1, doi. 10.1371/journal.pntd.0005680
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- Publication type:
- Article
Naloxonazine, an Amastigote-Specific Compound, Affects Leishmania Parasites through Modulation of Host-Encoded Functions.
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- PLoS Neglected Tropical Diseases, 2016, v. 10, n. 12, p. 1, doi. 10.1371/journal.pntd.0005234
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- Article
Two key cathepsins, TgCPB and TgCPL, are targeted by the vinyl sulfone inhibitor K11777 in in vitro and in vivo models of toxoplasmosis.
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- PLoS ONE, 2018, v. 13, n. 3, p. 1, doi. 10.1371/journal.pone.0193982
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- Article
Why Funding for Neglected Tropical Diseases Should Be a Global Priority.
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- Clinical Infectious Diseases, 2018, v. 67, n. 3, p. 323, doi. 10.1093/cid/ciy349
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- Article
High-Throughput Analysis of an RNAi Library Identifies Novel Kinase Targets in Trypanosoma brucei.
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- Chemical Biology & Drug Design, 2011, v. 78, n. 3, p. 454, doi. 10.1111/j.1747-0285.2011.01156.x
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- Article
Herbal melanin inhibits colorectal cancer cell proliferation by altering redox balance, inducing apoptosis, and modulating MAPK signaling.
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- Cancer Cell International, 2020, v. 20, n. 1, p. 1, doi. 10.1186/s12935-020-01206-x
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- Article
Predictions of novel Schistosoma mansoni - human protein interactions consistent with experimental data.
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- Scientific Reports, 2018, v. 8, n. 1, p. 1, doi. 10.1038/s41598-018-31272-1
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- Article
Heat shock protein 90 inhibitors repurposed against Entamoeba histolytica.
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- Frontiers in Microbiology, 2015, p. 1, doi. 10.3389/fmicb.2015.00368
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- Article
World Class Parasites: Vol. X, Schistosomiasis.
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- 2006
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- Book Review
Location, Location, Location: Five Facts about Tissue Tropism and Pathogenesis.
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- PLoS Pathogens, 2016, v. 12, n. 5, p. 1, doi. 10.1371/journal.ppat.1005519
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- Article
Utilizing Chemical Genomics to Identify Cytochrome b as a Novel Drug Target for Chagas Disease.
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- PLoS Pathogens, 2015, v. 11, n. 7, p. 1, doi. 10.1371/journal.ppat.1005058
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- Publication type:
- Article
Upregulation of Retinal Dehydrogenase 2 in Alternatively Activated Macrophages during Retinoid-dependent Type-2 Immunity to Helminth Infection in Mice.
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- PLoS Pathogens, 2012, v. 8, n. 8, p. 1, doi. 10.1371/journal.ppat.1002883
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- Article
The Trypanosoma cruzi Protease Cruzain Mediates Immune Evasion.
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- PLoS Pathogens, 2011, v. 7, n. 9, p. 1, doi. 10.1371/journal.ppat.1002139
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- Article
Murine embryonal carcinoma hybrids: Decreased ability to spontaneously differentiate as a dominant trait.
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- Journal of Cellular Physiology, 1981, v. 109, n. 2, p. 195, doi. 10.1002/jcp.1041090202
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- Publication type:
- Article
Long term follow-up of Trypanosoma cruzi infection and Chagas disease manifestations in mice treated with benznidazole or posaconazole.
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- PLoS Neglected Tropical Diseases, 2020, v. 14, n. 9, p. 1, doi. 10.1371/journal.pntd.0008726
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- Article
Molecular dissection of chagas induced cardiomyopathy reveals central disease associated and druggable signaling pathways.
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- PLoS Neglected Tropical Diseases, 2020, v. 14, n. 5, p. 1, doi. 10.1371/journal.pntd.0007980
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- Publication type:
- Article
Investigation of the Proteolytic Functions of an Expanded Cercarial Elastase Gene Family in Schistosoma mansoni.
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- PLoS Neglected Tropical Diseases, 2012, v. 6, n. 4, p. 1, doi. 10.1371/journal.pntd.0001589
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- Publication type:
- Article
WormAssay: A Novel Computer Application for Whole-Plate Motion-based Screening of Macroscopic Parasites.
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- PLoS Neglected Tropical Diseases, 2012, v. 6, n. 1, p. 1, doi. 10.1371/journal.pntd.0001494
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- Publication type:
- Article
WormAssay: A Novel Computer Application for Whole-Plate Motion-based Screening of Macroscopic Parasites.
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- PLoS Neglected Tropical Diseases, 2012, v. 6, n. 1, p. 1, doi. 10.1371/journal.pntd.0001494
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- Publication type:
- Article
Proteomic Identification of IPSE/alpha-1 as a Major Hepatotoxin Secreted by Schistosoma mansoni Eggs.
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- PLoS Neglected Tropical Diseases, 2011, v. 5, n. 10, p. 1, doi. 10.1371/journal.pntd.0001368
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- Publication type:
- Article
Proteomic Identification of IPSE/alpha-1 as a Major Hepatotoxin Secreted by Schistosoma mansoni Eggs.
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- PLoS Neglected Tropical Diseases, 2011, v. 5, n. 10, p. 1, doi. 10.1371/journal.pntd.0001368
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- Publication type:
- Article
Proteomic Analysis of Human Skin Treated with Larval Schistosome Peptidases Reveals Distinct Invasion Strategies among Species of Blood Flukes.
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- PLoS Neglected Tropical Diseases, 2011, v. 5, n. 9, p. 1, doi. 10.1371/journal.pntd.0001337
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- Article
Proteomic Analysis of Human Skin Treated with Larval Schistosome Peptidases Reveals Distinct Invasion Strategies among Species of Blood Flukes.
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- PLoS Neglected Tropical Diseases, 2011, v. 5, n. 9, p. 1, doi. 10.1371/journal.pntd.0001337
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- Article
A Screen against Leishmania Intracellular Amastigotes: Comparison to a Promastigote Screen and Identification of a Host Cell-Specific Hit.
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- PLoS Neglected Tropical Diseases, 2011, v. 5, n. 7, p. 1, doi. 10.1371/journal.pntd.0001253
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- Publication type:
- Article
A Screen against Leishmania Intracellular Amastigotes: Comparison to a Promastigote Screen and Identification of a Host Cell-Specific Hit.
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- PLoS Neglected Tropical Diseases, 2011, v. 5, n. 7, p. 1, doi. 10.1371/journal.pntd.0001253
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- Publication type:
- Article
Mining a Cathepsin Inhibitor Library for New Antiparasitic Drug Leads.
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- PLoS Neglected Tropical Diseases, 2011, v. 5, n. 5, p. 1, doi. 10.1371/journal.pntd.0001023
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- Article
Mining a Cathepsin Inhibitor Library for New Antiparasitic Drug Leads.
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- PLoS Neglected Tropical Diseases, 2011, v. 5, n. 5, p. 1, doi. 10.1371/journal.pntd.0001023
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- Article
RNA Interference in Schistosoma mansoni Schistosomula: Selectivity, Sensitivity and Operation for Larger-Scale Screening.
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- PLoS Neglected Tropical Diseases, 2010, v. 4, n. 10, p. 1, doi. 10.1371/journal.pntd.0000850
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- Article
RNA Interference in Schistosoma mansoni Schistosomula: Selectivity, Sensitivity and Operation for Larger-Scale Screening.
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- PLoS Neglected Tropical Diseases, 2010, v. 4, n. 10, p. 1, doi. 10.1371/journal.pntd.0000850
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- Article
In Vitro and In Vivo Studies of the Trypanocidal Properties of WRR-483 against Trypanosoma cruzi.
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- PLoS Neglected Tropical Diseases, 2010, v. 4, n. 9, p. 1, doi. 10.1371/journal.pntd.0000825
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- Article
In Vitro and In Vivo Studies of the Trypanocidal Properties of WRR-483 against Trypanosoma cruzi.
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- PLoS Neglected Tropical Diseases, 2010, v. 4, n. 9, p. 1, doi. 10.1371/journal.pntd.0000825
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- Article
Structural Characterization of CYP51 from Trypanosoma cruzi and Trypanosoma brucei Bound to the Antifungal Drugs Posaconazole and Fluconazole.
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- PLoS Neglected Tropical Diseases, 2010, v. 4, n. 4, p. 1, doi. 10.1371/journal.pntd.0000651
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- Publication type:
- Article
Structural Characterization of CYP51 from Trypanosoma cruzi and Trypanosoma brucei Bound to the Antifungal Drugs Posaconazole and Fluconazole.
- Published in:
- PLoS Neglected Tropical Diseases, 2010, v. 4, n. 4, p. 1, doi. 10.1371/journal.pntd.0000651
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- Publication type:
- Article
Delineation of Diverse Macrophage Activation Programs in Response to Intracellular Parasites and Cytokines.
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- PLoS Neglected Tropical Diseases, 2010, v. 4, n. 3, p. 1, doi. 10.1371/journal.pntd.0000648
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- Publication type:
- Article
Delineation of Diverse Macrophage Activation Programs in Response to Intracellular Parasites and Cytokines.
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- PLoS Neglected Tropical Diseases, 2010, v. 4, n. 3, p. 1, doi. 10.1371/journal.pntd.0000648
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- Publication type:
- Article
Drug Discovery for Schistosomiasis: Hit and Lead Compounds Identified in a Library of Known Drugs by Medium-Throughput Phenotypic Screening.
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- PLoS Neglected Tropical Diseases, 2009, v. 3, n. 7, p. 1, doi. 10.1371/journal.pntd.0000478
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- Article
Drug Discovery for Schistosomiasis: Hit and Lead Compounds Identified in a Library of Known Drugs by Medium-Throughput Phenotypic Screening.
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- PLoS Neglected Tropical Diseases, 2009, v. 3, n. 7, p. 1, doi. 10.1371/journal.pntd.0000478
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- Publication type:
- Article
SmCL3, a Gastrodermal Cysteine Protease of the Human Blood Fluke Schistosoma mansoni.
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- PLoS Neglected Tropical Diseases, 2009, v. 3, n. 6, p. 1, doi. 10.1371/journal.pntd.0000449
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- Publication type:
- Article
SmCL3, a Gastrodermal Cysteine Protease of the Human Blood Fluke Schistosoma mansoni.
- Published in:
- PLoS Neglected Tropical Diseases, 2009, v. 3, n. 6, p. 1
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- Publication type:
- Article
Host-pathogen protein interactions predicted by comparative modeling.
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- Protein Science: A Publication of the Protein Society, 2007, v. 16, n. 12, p. 2585, doi. 10.1110/ps.073228407
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- Article
Hormone receptors in hepatoblastoma: a demonstration of both estrogen and progesterone receptors.
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- 1982
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- Publication type:
- journal article
Editorial: Drug Development for Parasite-Induced Diarrheal Diseases.
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- 2017
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- Publication type:
- Editorial
Molecular Design, Synthesis and Trypanocidal Activity of Dipeptidyl Nitriles as Cruzain Inhibitors.
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- PLoS Neglected Tropical Diseases, 2015, v. 9, n. 7, p. 1, doi. 10.1371/journal.pntd.0003916
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- Publication type:
- Article
Machine Learning Models and Pathway Genome Data Base for Trypanosoma cruzi Drug Discovery.
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- PLoS Neglected Tropical Diseases, 2015, v. 9, n. 6, p. 1, doi. 10.1371/journal.pntd.0003878
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- Publication type:
- Article
Prolyl Oligopeptidase from the Blood Fluke Schistosoma mansoni: From Functional Analysis to Anti-schistosomal Inhibitors.
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- PLoS Neglected Tropical Diseases, 2015, v. 9, n. 6, p. 1, doi. 10.1371/journal.pntd.0003827
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- Publication type:
- Article
Prolyl Oligopeptidase from the Blood Fluke Schistosoma mansoni: From Functional Analysis to Anti-schistosomal Inhibitors.
- Published in:
- PLoS Neglected Tropical Diseases, 2015, v. 9, n. 6, p. 1, doi. 10.1371/journal.pntd.0003827
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- Publication type:
- Article
Machine Learning Models and Pathway Genome Data Base for Trypanosoma cruzi Drug Discovery.
- Published in:
- PLoS Neglected Tropical Diseases, 2015, v. 9, n. 6, p. 1, doi. 10.1371/journal.pntd.0003878
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- Publication type:
- Article
Targeting Ergosterol Biosynthesis in Leishmania donovani: Essentiality of Sterol 14alpha-demethylase.
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- PLoS Neglected Tropical Diseases, 2015, v. 9, n. 3, p. 1, doi. 10.1371/journal.pntd.0003588
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- Article