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The impact of physiological state and environmental stress on bacterial load estimation methodologies for Mycobacterium tuberculosis.
Published in:
Scientific Reports, 2024, v. 14, n. 1, p. 1, doi. 10.1038/s41598-024-74318-3
By:
- Maitra, Arundhati;
- Wijk, Marie;
- Margaryan, Hasmik;
- Denti, Paolo;
- McHugh, Timothy D.;
- Kloprogge, Frank
Publication type:
Article
Enhanced heterogeneity of rpoB in Mycobacterium tuberculosis found at low pH.
Published in:
Journal of Antimicrobial Chemotherapy (JAC), 2009, v. 63, n. 6, p. 1118, doi. 10.1093/jac/dkp125
By:
- Jenkins, Claire;
- Bacon, Joanna;
- Allnutt, Jon;
- Hatch, Kim A.;
- Bose, Alpana;
- OSullivan, Denise M.;
- Arnold, Catherine;
- Gillespie, Stephen H.;
- McHugh, Timothy D.
Publication type:
Article
Early bactericidal activity of a moxifloxacin and isoniazid combination in smear-positive pulmonary tuberculosis.
Published in:
Journal of Antimicrobial Chemotherapy (JAC), 2005, v. 56, n. 6, p. 1169, doi. 10.1093/jac/dki376
By:
- Stephen H. Gillespie;
- Roly D. Gosling;
- Leonard Uiso;
- Noel E. Sam;
- Esther G. Kanduma;
- Timothy D. McHugh
Publication type:
Article
Effect of subinhibitory concentrations of ciprofloxacin on <it>Mycobacterium fortuitum</it> mutation rates.
Published in:
Journal of Antimicrobial Chemotherapy (JAC), 2005, v. 56, n. 2, p. 344, doi. 10.1093/jac/dki191
By:
- Stephen H. Gillespie;
- Shreya Basu;
- Anne L. Dickens;
- Denise M. O'Sullivan;
- Timothy D. McHugh
Publication type:
Article
Analysis of rpoB and pncA mutations in the published literature: an insight into the role of oxidative stress in Mycobacterium tuberculosis evolution?
Published in:
Journal of Antimicrobial Chemotherapy (JAC), 2005, v. 55, n. 5, p. 674, doi. 10.1093/jac/dki069
By:
- Denise M. O'Sullivan;
- Timothy D. McHugh;
- Stephen H. Gillespie
Publication type:
Article
Improving the Tuberculosis Drug Development Pipeline.
Published in:
2015
By:
- Evangelopoulos, Dimitrios;
- McHugh, Timothy D.
Publication type:
Editorial
Mathematical models of drug-resistant tuberculosis lack bacterial heterogeneity: A systematic review.
Published in:
PLoS Pathogens, 2024, v. 20, n. 4, p. 1, doi. 10.1371/journal.ppat.1011574
By:
- Fuller, Naomi M.;
- McQuaid, Christopher F.;
- Harker, Martin J.;
- Weerasuriya, Chathika K.;
- McHugh, Timothy D.;
- Knight, Gwenan M.
Publication type:
Article
Improving the Drug Development Pipeline for Mycobacteria: Modelling Antibiotic Exposure in the Hollow Fibre Infection Model.
Published in:
Antibiotics (2079-6382), 2021, v. 10, n. 12, p. 1515, doi. 10.3390/antibiotics10121515
By:
- Maitra, Arundhati;
- Solanki, Priya;
- Sadouki, Zahra;
- McHugh, Timothy D.;
- Kloprogge, Frank
Publication type:
Article
Emergence of phenotypic and genotypic antimicrobial resistance in Mycobacterium tuberculosis.
Published in:
Scientific Reports, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41598-022-25827-6
By:
- Kloprogge, Frank;
- Ortiz Canseco, Julio;
- Phee, Lynette;
- Sadouki, Zahra;
- Kipper, Karin;
- Witney, Adam A.;
- Stoker, Neil;
- McHugh, Timothy D.
Publication type:
Article
Rifampicin Resistance in Tuberculosis Outbreak, London, England.
Published in:
Emerging Infectious Diseases, 2005, v. 11, n. 6, p. 931, doi. 10.3201/eid1106.050118
By:
- Jenkins, Claire;
- Claxton, Alleyna P.;
- Shorten, Robert J.;
- McHugh, Timothy D.;
- Gillespie, Stephen H.
Publication type:
Article
Cell-wall synthesis and ribosome maturation are co-regulated by an RNA switch in Mycobacterium tuberculosis.
Published in:
Nucleic Acids Research, 2018, v. 46, n. 11, p. 5837, doi. 10.1093/nar/gky226
By:
- Schwenk, Stefan;
- Moores, Alexandra;
- Nobeli, Irene;
- McHugh, Timothy D;
- Arnvig, Kristine B
Publication type:
Article
Role of pharmacogenetics in rifampicin pharmacokinetics and the potential effect on TB–rifampicin sensitivity among Ugandan patients.
Published in:
Transactions of the Royal Society of Tropical Medicine & Hygiene, 2020, v. 114, n. 2, p. 107, doi. 10.1093/trstmh/trz108
By:
- Mukonzo, Jackson K;
- Kengo, Allan;
- Kutesa, Bisaso;
- Nanzigu, Sarah;
- Pohanka, Anton;
- McHugh, Timothy D;
- Zumla, Alimuddin;
- Aklillu, Eleni
Publication type:
Article
World TB Day 2014: Reach the three million: a TB test, treatment and cure for all.
Published in:
Transactions of the Royal Society of Tropical Medicine & Hygiene, 2014, v. 108, n. 3, p. 119, doi. 10.1093/trstmh/tru006
By:
- McHugh, Timothy D.
Publication type:
Article
Antimicrobial resistance profiles of bacteria associated with lower respiratory tract infections in cats and dogs in England.
Published in:
Veterinary Record: Journal of the British Veterinary Association, 2022, v. 190, n. 4, p. no, doi. 10.1002/vetr.779
By:
- Mavrides, Daphne E.;
- Morgan, Alice L.;
- Na, Jea G.;
- Graham, Peter A.;
- McHugh, Timothy D.
Publication type:
Article
Toxicity associated with tuberculosis chemotherapy in the REMoxTB study.
Published in:
2018
By:
- Tweed, Conor D.;
- Crook, Angela M.;
- Amukoye, Evans I.;
- Dawson, Rodney;
- Diacon, Andreas H.;
- Hanekom, Madeline;
- McHugh, Timothy D.;
- Mendel, Carl M.;
- Meredith, Sarah K.;
- Murphy, Michael E.;
- Murthy, Saraswathi E.;
- Nunn, Andrew J.;
- Phillips, Patrick P. J.;
- Singh, Kasha P.;
- Spigelman, Melvin;
- Wills, Genevieve H.;
- Gillespie, Stephen H.
Publication type:
journal article
Target product profiles: tests for tuberculosis treatment monitoring and optimization.
Published in:
Bulletin of the World Health Organization, 2023, v. 101, n. 11, p. 730, doi. 10.2471/BLT.23.290901
By:
- Gupta-Wright, Ankur;
- den Boon, Saskia;
- MacLean, Emily L.;
- Cirillo, Daniela;
- Cobelens, Frank;
- Gillespie, Stephen H.;
- Mikashmi Kohli;
- Ruhwald, Morten;
- Savic, Rada;
- Brigden, Grania;
- Gidado, Mustapha;
- Goletti, Delia;
- Hanna, Debra;
- Hasan, Rumina;
- Hewison, Cathy;
- Koura, Kobto G.;
- Lienhard, Christian;
- Lungu, Patrick;
- McHugh, Timothy D.;
- McKenna, Lindsay
Publication type:
Article
Pediatric tuberculosis-human immunodeficiency virus co-infection in the United Kingdom highlights the need for better therapy monitoring tools: a case report.
Published in:
2017
By:
- Evangelopoulos, Dimitrios;
- Whittaker, Elizabeth;
- Honeyborne, Isobella;
- McHugh, Timothy D.;
- Klein, Nigel;
- Shingadia, Delane
Publication type:
journal article
Mycobacterium tuberculosis Is Resistant to Isoniazid at a Slow Growth Rate by Single Nucleotide Polymorphisms in katG Codon Ser315.
Published in:
PLoS ONE, 2015, v. 10, n. 9, p. 1, doi. 10.1371/journal.pone.0138253
By:
- Jeeves, Rose E.;
- Marriott, Alice A. N.;
- Pullan, Steven T.;
- Hatch, Kim A.;
- Allnutt, Jon C.;
- Freire-Martin, Irene;
- Hendon-Dunn, Charlotte L.;
- Watson, Robert;
- Witney, Adam A.;
- Tyler, Richard H.;
- Arnold, Catherine;
- Marsh, Philip D.;
- McHugh, Timothy D.;
- Bacon, Joanna
Publication type:
Article
Identification of 2-Aminothiazole-4-Carboxylate Derivatives Active against Mycobacterium tuberculosis H37Rv and the β-Ketoacyl-ACP Synthase mtFabH.
Published in:
PLoS ONE, 2009, v. 4, n. 5, p. 1, doi. 10.1371/journal.pone.0005617
By:
- Al-Balas, Qosay;
- Anthony, Nahoum G.;
- Al-Jaidi, Bilal;
- Alnimr, Amani;
- Abbott, Grainne;
- Brown, Alistair K.;
- Taylor, Rebecca C.;
- Besra, Gurdyal S.;
- McHugh, Timothy D.;
- Gillespie, Stephen H.;
- Johnston, Blair F.;
- Mackay, Simon P.;
- Coxon, Geoffrey D.
Publication type:
Article
Strategies and Challenges Involved in the Discovery of New Chemical Entities During Early-Stage Tuberculosis Drug Discovery.
Published in:
Journal of Infectious Diseases, 2012, v. 205, n. suppl_2, p. S258, doi. 10.1093/infdis/jis191
By:
- Coxon, Geoffrey D.;
- Cooper, Christopher B.;
- Gillespie, Stephen H.;
- McHugh, Timothy D.
Publication type:
Article
Tuberculosis Diagnostics and Biomarkers: Needs, Challenges, Recent Advances, and Opportunities.
Published in:
Journal of Infectious Diseases, 2012, v. 205, n. suppl_2, p. S147, doi. 10.1093/infdis/jir860
By:
- McNerney, Ruth;
- Maeurer, Markus;
- Abubakar, Ibrahim;
- Marais, Ben;
- Mchugh, Timothy D.;
- Ford, Nathan;
- Weyer, Karin;
- Lawn, Steve;
- Grobusch, Martin P.;
- Memish, Ziad;
- Squire, S. Bertel;
- Pantaleo, Giuseppe;
- Chakaya, Jeremiah;
- Casenghi, Martina;
- Migliori, Giovanni-Batista;
- Mwaba, Peter;
- Zijenah, Lynn;
- Hoelscher, Michael;
- Cox, Helen;
- Swaminathan, Soumya
Publication type:
Article
Drug-Resistant Tuberculosis—Current Dilemmas, Unanswered Questions, Challenges, and Priority Needs.
Published in:
Journal of Infectious Diseases, 2012, v. 205, n. suppl_2, p. S228, doi. 10.1093/infdis/jir858
By:
- Zumla, Alimuddin;
- Abubakar, Ibrahim;
- Raviglione, Mario;
- Hoelscher, Michael;
- Ditiu, Lucica;
- Mchugh, Timothy D.;
- Squire, S. Bertel;
- Cox, Helen;
- Ford, Nathan;
- McNerney, Ruth;
- Marais, Ben;
- Grobusch, Martin;
- Lawn, Stephen D.;
- Migliori, Giovanni-Battista;
- Mwaba, Peter;
- O'Grady, Justin;
- Pletschette, Michel;
- Ramsay, Andrew;
- Chakaya, Jeremiah;
- Schito, Marco
Publication type:
Article
A Step toward an Optimized Rifampin Dose Completed.
Published in:
2015
By:
- Boeree, Martin J;
- Diacon, Andreas H;
- Dawson, Rodney;
- Narunsky, Kim;
- du Bois, Jeannine;
- Venter, Amour;
- Phillips, Patrick P J;
- Gillespie, Stephen H;
- McHugh, Timothy D;
- Hoelscher, Michael;
- Heinrich, Norbert;
- Rehal, Sunita;
- van Soolingen, Dick;
- van Ingen, Jakko;
- Magis-Escurra, Cecile;
- Burger, David;
- Plemper van Balen, Georgette;
- Aarnoutse, Rob E
Publication type:
Letter
A Step toward an Optimized Rifampin Dose Completed.
Published in:
American Journal of Respiratory & Critical Care Medicine, 2015, v. 192, n. 4, p. 525, doi. 10.1164/rccm.201506-1061le
By:
- Boeree, Martin J.;
- Diacon, Andreas H.;
- Dawson, Rodney;
- Narunsky, Kim;
- du Bois, Jeannine;
- Venter, Amour;
- Phillips, Patrick P. J.;
- Gillespie, Stephen H.;
- McHugh, Timothy D.;
- Hoelscher, Michael;
- Heinrich, Norbert;
- Rehal, Sunita;
- van Soolingen, Dick;
- van Ingen, Jakko;
- Magis-Escurra, Cecile;
- Burger, David;
- van Balen, Georgette Plemper;
- Aarnoutse, Rob E.
Publication type:
Article
A Dose-Ranging Trial to Optimize the Dose of Rifampin in the Treatment of Tuberculosis.
Published in:
American Journal of Respiratory & Critical Care Medicine, 2015, v. 191, n. 9, p. 1058, doi. 10.1164/rccm.201407-1264OC
By:
- Boeree, Martin J.;
- Diacon, Andreas H.;
- Dawson, Rodney;
- Narunsky, Kim;
- du Bois, Jeannine;
- Venter, Amour;
- Phillips, Patrick P. J.;
- Gillespie, Stephen H.;
- McHugh, Timothy D.;
- Hoelscher, Michael;
- Heinrich, Norbert;
- Rehal, Sunita;
- van Soolingen, Dick;
- van Ingen, Jakko;
- Magis-Escurra, Cecile;
- Burger, David;
- van Balen, Georgette Plemper;
- Aarnoutse, Rob E.
Publication type:
Article
Detection and characterization of carbapenem resistant Gram‐negative bacilli isolates recovered from hospitalized patients at Soba University Hospital, Sudan.
Published in:
BMC Microbiology, 2021, v. 21, n. 1, p. 1, doi. 10.1186/s12866-021-02133-1
By:
- Elbadawi, Hana S.;
- Elhag, Kamal M.;
- Mahgoub, Elsheikh;
- Altayb, Hisham N.;
- Ntoumi, Francine;
- Elton, Linzy;
- McHugh, Timothy D.;
- Tembo, John;
- Ippolito, Giuseppe;
- Osman, Abdinasir Yusuf;
- Zumla, Alimuddin;
- Hamid, Muzamil M. Abdel
Publication type:
Article
Ertapenem and Faropenem against Mycobacterium tuberculosis: in vitro testing and comparison by macro and microdilution.
Published in:
BMC Microbiology, 2020, v. 20, n. 1, p. N.PAG, doi. 10.1186/s12866-020-01954-w
By:
- Gonzalo, Ximena;
- Satta, Giovanni;
- Ortiz Canseco, Julio;
- McHugh, Timothy D.;
- Drobniewski, Francis
Publication type:
Article
Liver toxicity associated with tuberculosis chemotherapy in the REMoxTB study.
Published in:
2018
By:
- Tweed, Conor Duncan;
- Wills, Genevieve Helen;
- Crook, Angela M.;
- Dawson, Rodney;
- Diacon, Andreas H.;
- Louw, Cheryl E.;
- McHugh, Timothy D.;
- Mendel, Carl;
- Meredith, Sarah;
- Mohapi, Lerato;
- Murphy, Michael E.;
- Murray, Stephen;
- Murthy, Sara;
- Nunn, Andrew J.;
- Phillips, Patrick P. J.;
- Singh, Kasha;
- Spigelman, M.;
- Gillespie, S. H.
Publication type:
journal article
A comparison of liquid and solid culture for determining relapse and durable cure in phase III TB trials for new regimens.
Published in:
2017
By:
- Phillips, Patrick P. J.;
- Mendel, Carl M.;
- Nunn, Andrew J.;
- McHugh, Timothy D.;
- Crook, Angela M.;
- Hunt, Robert;
- Bateson, Anna;
- Gillespie, Stephen H.
Publication type:
journal article
Spot sputum samples are at least as good as early morning samples for identifying Mycobacterium tuberculosis.
Published in:
2017
By:
- Murphy, Michael E.;
- Phillips, Patrick P. J.;
- Mendel, Carl M.;
- Bongard, Emily;
- Bateson, Anna L. C.;
- Hunt, Robert;
- Murthy, Saraswathi;
- Singh, Kasha P.;
- Brown, Michael;
- Crook, Angela M.;
- Nunn, Andrew J.;
- Meredith, Sarah K.;
- Lipman, Marc;
- McHugh, Timothy D.;
- Gillespie, Stephen H.;
- REMoxTB Consortium
Publication type:
journal article
Use of whole-genome sequencing to distinguish relapse from reinfection in a completed tuberculosis clinical trial.
Published in:
2017
By:
- Witney, Adam A.;
- Bateson, Anna L. E.;
- Jindani, Amina;
- Phillips, Patrick P. J.;
- Coleman, David;
- Stoker, Neil G.;
- Butcher, Philip D.;
- McHugh, Timothy D.;
- RIFAQUIN Study Team
Publication type:
journal article
Blood and sputum eosinophils in COPD; relationship with bacterial load.
Published in:
2017
By:
- Kolsum, Umme;
- Donaldson, Gavin C.;
- Singh, Richa;
- Barker, Bethan L.;
- Gupta, Vandana;
- George, Leena;
- Webb, Adam J.;
- Thurston, Sarah;
- Brookes, Anthony J.;
- McHugh, Timothy D.;
- Wedzicha, Jadwiga A.;
- Brightling, Christopher E.;
- Singh, Dave
Publication type:
journal article
Clinical application of whole-genome sequencing in the management of extensively drug-resistant tuberculosis: a case report.
Published in:
2024
By:
- Katale, Bugwesa Z.;
- Rofael, Sylvia;
- Elton, Linzy;
- Mbugi, Erasto V.;
- Mpagama, Stella G.;
- Mtunga, Daphne;
- Mafie, Maryjesca G.;
- Mbelele, Peter M.;
- Williams, Charlotte;
- Mvungi, Happiness C.;
- Williams, Rachel;
- Saku, Gulinja A.;
- Ruta, Joanitha A.;
- McHugh, Timothy D.;
- Matee, Mecky I.
Publication type:
Case Study
Pre-Clinical Tools for Predicting Drug Efficacy in Treatment of Tuberculosis.
Published in:
Microorganisms, 2022, v. 10, n. 3, p. 514, doi. 10.3390/microorganisms10030514
By:
- Margaryan, Hasmik;
- Evangelopoulos, Dimitrios D.;
- Muraro Wildner, Leticia;
- McHugh, Timothy D.
Publication type:
Article
Culture-Free Enumeration of Mycobacterium tuberculosis in Mouse Tissues Using the Molecular Bacterial Load Assay for Preclinical Drug Development.
Published in:
Microorganisms, 2022, v. 10, n. 2, p. N.PAG, doi. 10.3390/microorganisms10020460
By:
- Evangelopoulos, Dimitrios;
- Shoen, Carolyn M.;
- Honeyborne, Isobella;
- Clark, Simon;
- Williams, Ann;
- Mukamolova, Galina V.;
- Cynamon, Michael H.;
- McHugh, Timothy D.
Publication type:
Article
Application of Bacteriophages for Mycobacterial Infections, from Diagnosis to Treatment.
Published in:
Microorganisms, 2021, v. 9, n. 11, p. 2366, doi. 10.3390/microorganisms9112366
By:
- Shield, Christopher G.;
- Swift, Benjamin M. C.;
- McHugh, Timothy D.;
- Dedrick, Rebekah M.;
- Hatfull, Graham F.;
- Satta, Giovanni
Publication type:
Article
The effect of HIV status on the frequency and severity of acute respiratory illness.
Published in:
PLoS ONE, 2020, v. 15, n. 5, p. 1, doi. 10.1371/journal.pone.0232977
By:
- Brown, James;
- Pickett, Elisha;
- Smith, Colette;
- Sachikonye, Memory;
- Brooks, Lucy;
- Mahungu, Tabitha;
- Lowe, David M.;
- Madge, Sara;
- Youle, Mike;
- Johnson, Margaret;
- Hurst, John R.;
- McHugh, Timothy D.;
- Abubakar, Ibrahim;
- Lipman, Marc
Publication type:
Article
TB-PRACTECAL: study protocol for a randomised, controlled, open-label, phase II-III trial to evaluate the safety and efficacy of regimens containing bedaquiline and pretomanid for the treatment of adult patients with pulmonary multidrug-resistant tuberculosis.
Published in:
2022
By:
- Berry, Catherine;
- du Cros, Philipp;
- Fielding, Katherine;
- Gajewski, Suzanne;
- Kazounis, Emil;
- McHugh, Timothy D.;
- Merle, Corinne;
- Motta, Ilaria;
- Moore, David A. J.;
- Nyang'wa, Bern-Thomas
Publication type:
journal article
Drug-induced hepatotoxicity and association with slow acetylation variants NAT2*5 and NAT2*6 in Cameroonian patients with tuberculosis and HIV co-infection.
Published in:
BMC Infectious Diseases, 2024, v. 24, n. 1, p. 1, doi. 10.1186/s12879-024-09638-w
By:
- Cho, Frederick Nchang;
- Achidi, Eric A.;
- Enoh, Jude Eteneneng;
- Pallerla, Srinivas Reddy;
- Linh, Le Thi Kieu;
- Tong, Hoang Van;
- Kamgno, Joseph;
- Penlap, Véronique Beng;
- Adegnika, Ayola Akim;
- Lekana-Douki, Jean-Bernard;
- Bouyou-Akotet, Marielle Karine;
- Kahunu, Gauthier Mesia;
- Lutete, Gaston Tona;
- Bates, Mathew;
- Tembo, John;
- Elton, Linzy;
- McHugh, Timothy D;
- Grobusch, Martin P;
- Zumla, Alimuddin;
- Ntoumi, Francine
Publication type:
Article
Acetic Acid Enables Molecular Enumeration of Mycobacterium tuberculosis from Sputum and Eliminates the Need for a Biosafety Level 3 Laboratory.
Published in:
Clinical Chemistry, 2024, v. 70, n. 4, p. 642, doi. 10.1093/clinchem/hvae013
By:
- Palekyte, Ana;
- Morkowska, Anna;
- Billington, Owen;
- Morris-Jones, Stephen;
- Millard, James;
- Marakalala, Mohlopheni J;
- Owolabi, Olumuyiwa;
- Sambou, Basil;
- Zumla, Alimuddin;
- Sutherland, Jayne S;
- McHugh, Timothy D;
- Honeyborne, Isobella
Publication type:
Article
Cautionary Note on Contamination of Reagents Used for Molecular Detection of SARS-CoV-2.
Published in:
Clinical Chemistry, 2020, v. 66, n. 11, p. 1369, doi. 10.1093/clinchem/hvaa214
By:
- Huggett, Jim F.;
- Benes, Vladimir;
- Bustin, Stephen A.;
- Garson, Jeremy A.;
- Harris, Karthyn;
- Kammel, Martin;
- Kubista, Mikael;
- McHugh, Timothy D.;
- Moran-Gilad, Jacob;
- Nolan, Tania;
- Pfaffl, Michael W.;
- Salit, Marc;
- Shipley, Greg;
- Vallone, Peter M.;
- Vandesompele, Jo;
- Wittwer, Carl;
- Zeichhardt, Heinz
Publication type:
Article
Validation of Differentially Expressed Immune Biomarkers in Latent and Active Tuberculosis by Real-Time PCR.
Published in:
Frontiers in Immunology, 2021, v. 11, p. N.PAG, doi. 10.3389/fimmu.2020.612564
By:
- Perumal, Prem;
- Abdullatif, Mohamed Bilal;
- Garlant, Harriet N.;
- Honeyborne, Isobella;
- Lipman, Marc;
- McHugh, Timothy D.;
- Southern, Jo;
- Breen, Ronan;
- Santis, George;
- Ellappan, Kalaiarasan;
- Kumar, Saka Vinod;
- Belgode, Harish;
- Abubakar, Ibrahim;
- Sinha, Sanjeev;
- Vasan, Seshadri S.;
- Joseph, Noyal;
- Kempsell, Karen E.
Publication type:
Article
Bacteremia in a human caused by an XDR strain of Pseudomonas fulva.
Published in:
Journal of Infection in Developing Countries, 2018, v. 12, n. 7, p. 597, doi. 10.3855/jidc.10326
By:
- Uddin, Fakhur;
- Roulston, Kerry;
- McHugh, Timothy D.;
- Khan, Taseer Ahmed;
- Sohail, Muhammad
Publication type:
Article
Genomic Investigations Unmask Mycoplasma amphoriforme, a New Respiratory Pathogen.
Published in:
Clinical Infectious Diseases, 2015, v. 60, n. 3, p. 381, doi. 10.1093/cid/ciu820
By:
- Gillespie, Stephen H.;
- Clare L. Ling;
- Oravcova, Katarina;
- Pinheiro, Miguel;
- Wells, Louise;
- Bryant, Josephine M.;
- McHugh, Timothy D.;
- Bébéar, Cecile;
- Webster, David;
- Harris, Simon R.;
- Seth-Smith, Helena M. B.;
- Thomson, Nicholas R.
Publication type:
Article
Toxicity related to standard TB therapy for pulmonary tuberculosis and treatment outcomes in the REMoxTB study according to HIV status.
Published in:
2019
By:
- Tweed, Conor D.;
- Crook, Angela M.;
- Dawson, Rodney;
- Diacon, Andreas H.;
- McHugh, Timothy D.;
- Mendel, Carl M.;
- Meredith, Sarah K.;
- Mohapi, Lerato;
- Murphy, Michael E.;
- Nunn, Andrew J.;
- Phillips, Patrick P. J.;
- Singh, Kasha P.;
- Spigelman, Melvin;
- Gillespie, Stephen H.
Publication type:
journal article
DNA sequence-selective C8-linked pyrrolobenzodiazepine-heterocyclic polyamide conjugates show anti-tubercular-specific activities.
Published in:
Journal of Antibiotics, 2016, v. 69, n. 12, p. 843, doi. 10.1038/ja.2016.43
By:
- Brucoli, Federico;
- Guzman, Juan D;
- Basher, Mohammad A;
- Evangelopoulos, Dimitrios;
- McMahon, Eleanor;
- Munshi, Tulika;
- McHugh, Timothy D;
- Fox, Keith R;
- Bhakta, Sanjib
Publication type:
Article
A comparison of phenotypic and WGS drug susceptibility testing in Mycobacterium tuberculosis isolates from the Republic of Korea.
Published in:
JAC-Antimicrobial Resistance, 2023, v. 5, n. 3, p. 1, doi. 10.1093/jacamr/dlad056
By:
- Seung Heon Lee;
- Ferran, Elena;
- Witney, Adam A.;
- Sungweon Ryu;
- Hyungseok Kang;
- Storey, Nathaniel;
- McHugh, Timothy D.;
- Satta, Giovanni
Publication type:
Article
Alcaloides aporfínicos con actividad antituberculosa aislados de Ocotea discolor Kunth (Lauraceae).
Published in:
Revista Colombiana de Química, 2017, v. 46, n. 3, p. 22, doi. 10.15446/rev.colomb.quim.v46n3.62963
By:
- Albarracín, Lady T.;
- Patiño, Oscar J.;
- Guzman, Juan D.;
- Begum, Neelu;
- McHugh, Timothy D.;
- Cuca, Luis E.;
- Ávila, Mónica C.
Publication type:
Article
Investigation of the mycobacterial enzyme HsaD as a potential novel target for anti-tubercular agents using a fragment-based drug design approach.
Published in:
2017
By:
- Ryan, Ali;
- Polycarpou, Elena;
- Lack, Nathan A;
- Evangelopoulos, Dimitrios;
- Sieg, Christian;
- Halman, Alice;
- Bhakta, Sanjib;
- Eleftheriadou, Olga;
- McHugh, Timothy D;
- Keany, Sebastian;
- Lowe, Edward D;
- Ballet, Romain;
- Abuhammad, Areej;
- Jacobs, William R;
- Ciulli, Alessio;
- Sim, Edith;
- Jacobs, William R Jr
Publication type:
journal article
Repurposing drugs for treatment of tuberculosis: a role for non-steroidal anti-inflammatory drugs.
Published in:
British Medical Bulletin, 2016, v. 118, n. 1, p. 145, doi. 10.1093/bmb/ldw019
By:
- Maitra, Arundhati;
- Bates, Sadé;
- Shaik, Monisha;
- Evangelopoulos, Dimitrios;
- Abubakar, Ibrahim;
- McHugh, Timothy D.;
- Lipman, Marc;
- Bhakta, Sanjib
Publication type:
Article

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