Works matching AU McHugh, Simon

Results: 13

Identification of BDNF Sensitive Electrophysiological Markers of Synaptic Activity and Their Structural Correlates in Healthy Subjects Using a Genetic Approach Utilizing the Functional BDNF Val66Met Polymorphism.

Published in:

PLoS ONE, 2014, v. 9, n. 4, p. 1, doi. 10.1371/journal.pone.0095558

By:

Soltész, Fruzsina;
Suckling, John;
Lawrence, Phil;
Tait, Roger;
Ooi, Cinly;
Bentley, Graham;
Dodds, Chris M.;
Miller, Sam R.;
Wille, David R.;
Byrne, Misha;
McHugh, Simon M.;
Bellgrove, Mark A.;
Croft, Rodney J.;
Lu, Bai;
Bullmore, Edward T.;
Nathan, Pradeep J.

Publication type:

Article

Effects of the BDNF Val66Met Polymorphism and Met Allele Load on Declarative Memory Related Neural Networks.

Published in:

PLoS ONE, 2013, v. 8, n. 11, p. 1, doi. 10.1371/journal.pone.0074133

By:

Dodds, Chris M.;
Henson, Richard N.;
Suckling, John;
Miskowiak, Kamilla W.;
Ooi, Cinly;
Tait, Roger;
Soltesz, Fruzsina;
Lawrence, Phil;
Bentley, Graham;
Maltby, Kay;
Skeggs, Andrew;
Miller, Sam R.;
McHugh, Simon;
Bullmore, Edward T.;
Nathan, Pradeep J.

Publication type:

Article

Safety, tolerability, pharmacokinetics, and pharmacodynamics of single-dose anti-interleukin-18 mAb GSK1070806 in healthy and obese subjects.

Published in:

International Journal of Clinical Pharmacology & Therapeutics, 2014, v. 52, n. 10, p. 867, doi. 10.5414/CP202087

By:

Mistry, Prafull;
Reid, Juliet;
Pouliquen, Isabelle;
McHugh, Simon;
Abberley, Lee;
DeWall, Stephen;
Taylor, Adam;
Xin Tong;
Rocha del Cura, Marian;
McKie, Elizabeth

Publication type:

Article

Late cortical plasticity in motor and auditory cortex: role of met-allele in BDNF Val66Met polymorphism.

Published in:

International Journal of Neuropsychopharmacology, 2014, v. 17, n. 5, p. 705, doi. 10.1017/S1461145713001636

By:

Teo, James T. H.;
Bentley, Graham;
Lawrence, Philip;
Soltesz, Fruzsina;
Miller, Sam;
Willé, David;
McHugh, Simon;
Dodds, Chris;
Lu, Bai;
Croft, Rodney J.;
Bullmore, Edward T.;
Nathan, Pradeep J.

Publication type:

Article

Anti‐IL‐7 receptor α monoclonal antibody (GSK2618960) in healthy subjects – a randomized, double‐blind, placebo‐controlled study.

Published in:

British Journal of Clinical Pharmacology, 2019, v. 85, n. 2, p. 304, doi. 10.1111/bcp.13748

By:

Ellis, Joanne;
Maurik, Andre;
Fortunato, Lea;
Brown, Kim;
Brett, Sara;
Craigen, Jenny L.;
Gray, Frank;
Thompson, Paul W.;
Gisbert, Sophie;
Chen, Keguan;
Schwartz, Ann;
McHugh, Simon;
Want, Andrew;
Santos Franco, Sara;
Oliveira, Joao‐Joaquim;
Price, Jeffrey;
Davis, Bill;
Fernando, Disala;
Cheriyan, Joseph;
Kousin‐Ezewu, Onajite

Publication type:

Article

Pharmacokinetic and pharmacodynamic profiling of a P2X7 receptor allosteric modulator GSK1482160 in healthy human subjects.

Published in:

British Journal of Clinical Pharmacology, 2013, v. 75, n. 1, p. 197, doi. 10.1111/j.1365-2125.2012.04320.x

By:

Ali, Zahid;
Laurijssens, Bart;
Ostenfeld, Thor;
McHugh, Simon;
Stylianou, Anastasia;
Scott‐Stevens, Paul;
Hosking, Louise;
Dewit, Odile;
Richardson, Jill C.;
Chen, Chao

Publication type:

Article

Effects of genetic variation in the P2RX7 gene on pharmacodynamics of a P2X7 receptor antagonist: a prospective genotyping approach.

Published in:

British Journal of Clinical Pharmacology, 2012, v. 74, n. 2, p. 376, doi. 10.1111/j.1365-2125.2012.04200.x

By:

McHugh, Simon M.;
Roman, Shilina;
Davis, Bill;
Koch, Annelize;
Pickett, Alison M.;
Richardson, Jill C.;
Miller, Sam R.;
Wetten, Sally;
Cox, Charles J.;
Karpe, Fredrik;
Todd, John A.;
Bullmore, Edward T.

Publication type:

Article

Use of Entero-Test, a simple approach for non-invasive clinical evaluation of the biliary disposition of drugs.

Published in:

British Journal of Clinical Pharmacology, 2011, v. 72, n. 1, p. 133, doi. 10.1111/j.1365-2125.2011.03956.x

By:

Guiney, William J.;
Beaumont, Claire;
Thomas, Steve R.;
Robertson, Darren C.;
McHugh, Simon M.;
Koch, Annelize;
Richards, Duncan

Publication type:

Article

Characterisation of the clinical and activated T cell response to repeat delayed-type hypersensitivity skin challenges in human subjects, with KLH and PPD, as a potential model to test T cell-targeted therapies.

Published in:

Inflammation Research, 2016, v. 65, n. 5, p. 389, doi. 10.1007/s00011-016-0923-4

By:

Belson, Alexandra;
Schmidt, Tim;
Fernando, Disala;
Hardes, Kelly;
Scott, Nicola;
Brett, Sara;
Clark, Deborah;
Oliveira, João;
Davis, Bill;
McHugh, Simon;
Stone, John

Publication type:

Article

Kinetics and functional implications of Th1 and Th2 cytokine production following activation of peripheral blood mononuclear cells in primary culture.

Published in:

European Journal of Immunology, 1996, v. 26, n. 6, p. 1260, doi. 10.1002/eji.1830260612

By:

McHugh, Simon;
Deighton, John;
Rifkin, Ian;
Ewan, Pamela

Publication type:

Article

To bee or not to be? T-cell responses to bee venom PLA2 in relation to anaphylaxis and immunotherapy.

Published in:

1997

By:

McHugh, Simon M.

Publication type:

Editorial

Immunological responses to immunotherapy.

Published in:

1996

By:

McHugh, Simon

Publication type:

Editorial

Transcriptomic effects of rs4845604, an IBD and allergy-associated RORC variant, in stimulated ex vivo CD4+ T cells.

Published in:

PLoS ONE, 2021, v. 16, n. 10, p. 1, doi. 10.1371/journal.pone.0258316

By:

Wilson, Paul A.;
Santos Franco, Sara;
He, Liu;
Galwey, Nicholas W.;
Meakin, Jackie;
McIntyre, Rebecca;
McHugh, Simon M.;
Nolan, Michael A.;
Spain, Sarah L.;
Carlson, Thaddeus;
Lobera, Mercedes;
Rubio, Justin P.;
Davis, Bill;
McCarthy, Linda C.

Publication type:

Article

Works matching AU McHugh, Simon

Identification of BDNF Sensitive Electrophysiological Markers of Synaptic Activity and Their Structural Correlates in Healthy Subjects Using a Genetic Approach Utilizing the Functional BDNF Val66Met Polymorphism.

Effects of the <i>BDNF</i> Val66Met Polymorphism and Met Allele Load on Declarative Memory Related Neural Networks.

Safety, tolerability, pharmacokinetics, and pharmacodynamics of single-dose anti-interleukin-18 mAb GSK1070806 in healthy and obese subjects.

Late cortical plasticity in motor and auditory cortex: role of met-allele in BDNF Val66Met polymorphism.

Anti‐IL‐7 receptor α monoclonal antibody (GSK2618960) in healthy subjects – a randomized, double‐blind, placebo‐controlled study.

Pharmacokinetic and pharmacodynamic profiling of a P2X7 receptor allosteric modulator GSK1482160 in healthy human subjects.

Effects of genetic variation in the P2RX7 gene on pharmacodynamics of a P2X<sub>7</sub> receptor antagonist: a prospective genotyping approach.

Use of Entero-Test, a simple approach for non-invasive clinical evaluation of the biliary disposition of drugs.

Characterisation of the clinical and activated T cell response to repeat delayed-type hypersensitivity skin challenges in human subjects, with KLH and PPD, as a potential model to test T cell-targeted therapies.

Kinetics and functional implications of Th1 and Th2 cytokine production following activation of peripheral blood mononuclear cells in primary culture.

To bee or not to be? T-cell responses to bee venom PLA<sub>2</sub> in relation to anaphylaxis and immunotherapy.

Immunological responses to immunotherapy.

Transcriptomic effects of rs4845604, an IBD and allergy-associated RORC variant, in stimulated ex vivo CD4+ T cells.