Works matching AU McCrea, Jacqueline B.

Results: 31

Pharmacokinetics, Safety, and Tolerability of Letermovir Following Single‐ and Multiple‐Dose Administration in Healthy Japanese Subjects.

Published in:

Clinical Pharmacology in Drug Development, 2022, v. 11, n. 8, p. 938, doi. 10.1002/cpdd.1081

By:

Asari, Kazuhiko;
Ishii, Mikio;
Yoshitsugu, Hiroyuki;
Wakana, Akira;
Fancourt, Craig;
Yoon, Esther;
Furihata, Kenichi;
McCrea, Jacqueline B.;
Stoch, S. Aubrey;
Iwamoto, Marian

Publication type:

Article

Drug‐Drug Interaction of Letermovir and Atorvastatin in Healthy Participants.

Published in:

Clinical Pharmacology in Drug Development, 2022, v. 11, n. 4, p. 420, doi. 10.1002/cpdd.1071

By:

McCrea, Jacqueline B.;
Menzel, Karsten;
Adedoyin, Adedayo;
Cho, Carolyn R.;
Fox‐Bosetti, Sabrina;
Macha, Sreeraj;
Zhao, Tian;
Liu, Fang;
Panebianco, Deborah;
Stoch, S. Aubrey;
Iwamoto, Marian

Publication type:

Article

Assessment of Pharmacokinetic Interaction Between Gefapixant (MK‐7264), a P2X3 Receptor Antagonist, and the OATP1B1 Drug Transporter Substrate Pitavastatin.

Published in:

Clinical Pharmacology in Drug Development, 2022, v. 11, n. 3, p. 406, doi. 10.1002/cpdd.1047

By:

McCrea, Jacqueline B.;
Hussain, Azher;
Ma, Bennett;
Garrett, Graigory C.;
Evers, Raymond;
Laabs, John E.;
Stoch, S. Aubrey;
Iwamoto, Marian

Publication type:

Article

Assessment of Pharmacokinetic Interaction Between Letermovir and Fluconazole in Healthy Participants.

Published in:

Clinical Pharmacology in Drug Development, 2021, v. 10, n. 2, p. 198, doi. 10.1002/cpdd.852

By:

Adedoyin, Adedayo;
Fancourt, Craig;
Menzel, Karsten;
Zhao, Tian;
Tomek, Charles;
Panebianco, Deborah;
McCrea, Jacqueline B.;
Stoch, S. Aubrey;
Iwamoto, Marian

Publication type:

Article

Acute and Chronic Effects of Rifampin on Letermovir Suggest Transporter Inhibition and Induction Contribute to Letermovir Pharmacokinetics.

Published in:

Clinical Pharmacology & Therapeutics, 2022, v. 111, n. 3, p. 664, doi. 10.1002/cpt.2510

By:

Robbins, Jonathan A.;
Menzel, Karsten;
Lassman, Michael;
Zhao, Tian;
Fancourt, Craig;
Chu, Xiaoyan;
Mostoller, Kate;
Witter, Rose;
Marceau West, Rachel;
Stoch, S. Aubrey;
McCrea, Jacqueline B.;
Iwamoto, Marian

Publication type:

Article

A phase 1 pooled PK/PD analysis of bone resorption biomarkers for odanacatib, a Cathepsin K inhibitor.

Published in:

Journal of Pharmacokinetics & Pharmacodynamics, 2020, v. 47, n. 5, p. 473, doi. 10.1007/s10928-020-09699-9

By:

Zajic, Stefan;
Stoch, S. Aubrey;
McCrea, Jacqueline B.;
Witter, Rose;
Fayad, Ghassan N.;
Martinho, Monika;
Stone, Julie A.

Publication type:

Article

Evaluation of the inhibitory effects of itraconazole on letermovir.

Published in:

British Journal of Clinical Pharmacology, 2023, v. 89, n. 7, p. 2122, doi. 10.1111/bcp.15677

By:

McCrea, Jacqueline B.;
Menzel, Karsten;
Fancourt, Craig;
Witter, Rose;
Zhao, Tian;
Robbins, Jonathan A.;
Stoch, S. Aubrey;
Iwamoto, Marian

Publication type:

Article

A drug–drug interaction study with letermovir and acyclovir in healthy participants.

Published in:

British Journal of Clinical Pharmacology, 2023, v. 89, n. 5, p. 1690, doi. 10.1111/bcp.15648

By:

Menzel, Karsten;
McCrea, Jacqueline B.;
Fancourt, Craig;
Witter, Rose;
Zhao, Tian;
Stoch, S. Aubrey;
Iwamoto, Marian

Publication type:

Article

Clinical and translational pharmacology of the cathepsin K inhibitor odanacatib studied for osteoporosis.

Published in:

British Journal of Clinical Pharmacology, 2019, v. 85, n. 6, p. 1072, doi. 10.1111/bcp.13869

By:

Stone, Julie A.;
McCrea, Jacqueline B.;
Witter, Rose;
Zajic, Stefan;
Stoch, S. Aubrey

Publication type:

Article

A Single- and Multiple-Dose Study to Evaluate the Pharmacokinetics of Fixed-Dose Grazoprevir/Elbasvir in Healthy Chinese Participants.

Published in:

Clinical Pharmacology, 2020, v. 12, p. 1, doi. 10.2147/CPAA.S224662

By:

Li, Haiyan;
Yang, Zhenhua;
Zhang, Shuang;
Xu, Lin;
Wei, Yudong;
Jiang, Jun;
Caro, Luzelena;
Feng, Hwa-Ping;
McCrea, Jacqueline B;
Li, Meng;
Xie, Shuang;
Wang, Jiangdian;
Zhao, Xu Min;
Mu, Shengmei

Publication type:

Article

Developing a mechanistic understanding of the nonlinear pharmacokinetics of letermovir and prospective drug interaction with everolimus using physiological‐based pharmacokinetic modeling.

Published in:

CTS: Clinical & Translational Science, 2023, v. 16, n. 6, p. 1039, doi. 10.1111/cts.13509

By:

Menzel, Karsten;
Kuo, Yuhsin;
Chen, Dapeng;
Hartmann, Georgy;
Wang, Ying‐Hong;
Cho, Carolyn R.;
McCrea, Jacqueline B.;
Asari, Kazuhiko

Publication type:

Article

Tolerability, pharmacokinetics and night-time effects on postural sway and critical flicker fusion of gaboxadol and zolpidem in elderly subjects.

Published in:

British Journal of Clinical Pharmacology, 2009, v. 67, n. 2, p. 180, doi. 10.1111/j.1365-2125.2008.03331.x

By:

Boyle, Julia;
Danjou, Philippe;
Alexander, Robert;
Calder, Nicole;
Gargano, Cynthia;
Agrawal, Nancy;
Fu, Irong;
McCrea, Jacqueline B.;
Murphy, M. Gail

Publication type:

Article

Repeatability of local forearm vasoconstriction to endothelin-1 measured by venous occlusion plethysmography.

Published in:

British Journal of Clinical Pharmacology, 2002, v. 54, n. 4, p. 386, doi. 10.1046/j.1365-2125.2002.01653.x

By:

Strachan, Fiona E.;
Newby, David E.;
Sciberras, David G.;
McCrea, Jacqueline B.;
Goldberg, Michael R.;
Webb, David J.

Publication type:

Article

Correction to: Effect of CYP3A Inhibition and Induction on the Pharmacokinetics of Suvorexant: Two Phase I, Open-Label, Fixed-Sequence Trials in Healthy Subjects.

Published in:

2019

By:

Wrishko, Rebecca E.;
McCrea, Jacqueline B.;
Yee, Ka Lai;
Liu, Wen;
Panebianco, Deborah;
Mangin, Eric;
Chakravarthy, Manu;
Martinez-Cantarin, Maria P.;
Kraft, Walter K.

Publication type:

Correction Notice

Effect of CYP3A Inhibition and Induction on the Pharmacokinetics of Suvorexant: Two Phase I, Open-Label, Fixed-Sequence Trials in Healthy Subjects.

Published in:

Clinical Drug Investigation, 2019, v. 39, n. 5, p. 441, doi. 10.1007/s40261-019-00764-x

By:

Wrishko, Rebecca E.;
McCrea, Jacqueline B.;
Yee, Ka Lai;
Liu, Wen;
Panebianco, Deborah;
Mangin, Eric;
Chakravarthy, Manu;
Martinez-Cantarin, Maria P.;
Kraft, Walter K.

Publication type:

Article

Indinavir and Rifabutin Drug Interactions in Healthy Volunteers.

Published in:

Journal of Clinical Pharmacology, 2004, v. 44, n. 3, p. 305

By:

Walter K. Kraft;
Jacqueline B. McCrea;
Gregory A. Winchell;
Alexandra Carides;
Richard Lowry;
Eric J. Woolf;
Sandra E. Kusma;
Paul J. Deutsch;
Howard E. Greenberg;
Scott A. Waldman

Publication type:

Article

Single- and Multiple-Dose Pharmacokinetics of Etoricoxib, a Selective Inhibitor of Cyclooxygenase-2, in Man.

Published in:

Journal of Clinical Pharmacology, 2003, v. 43, n. 3, p. 268, doi. 10.1177/0091270003251122

By:

Agrawal, Nancy G.B.;
Porras, Arturo G.;
Matthews, Catherine Z.;
Rose, Mark J.;
Woolf, Eric J.;
Musser, Bret J.;
Dynder, Andrea L.;
Mazina, Katherine E.;
Lasseter, Kenneth C.;
Hunt, Thomas L.;
Schwartz, Jules I.;
McCrea, Jacqueline B.;
Gottesdiener, Keith M.

Publication type:

Article

Absence of a Pharmacokinetic Interaction between Losartan and Hydrochlorothiazide.

Published in:

1995

By:

McCrea, Jacqueline B.;
Lo, Man-Wai;
Tomasko, Lisa;
Lin, Charles C.;
Hsieh, John Y.-K.;
Capra, Nancy L.;
Goldberg, Michael R.

Publication type:

Other

Lovastatin Does Not Affect Oral Glucose Tolerance in Hypercholesterolemic Patients.

Published in:

1993

By:

McCrea, Jacqueline B.;
Fruncillo, Richard J.;
Holland, Sherry D.;
Conwy, Joyce A.;
Shingo, Sumiko;
Spector, Reynold;
Bjornsson, Thorir D.

Publication type:

Other

Effects of aprepitant on cytochrome P450 3A4 activity using midazolam as a probe*.

Published in:

Clinical Pharmacology & Therapeutics, 2003, v. 74, n. 2, p. 150, doi. 10.1016/S0009-9236(03)00123-1

By:

Majumdar, Anup K.;
McCrea, Jacqueline B.;
Panebianco, Deborah L.;
Hesney, Michael;
Dru, James;
Constanzer, Marvin;
Goldberg, Michael R.;
Murphy, Gail;
Gottesdiener, Keith M.;
Lines, Christopher R.;
Petty, Kevin J.;
Blum, Robert A.

Publication type:

Article

Effects of the neurokinin1 receptor antagonist aprepitant on the pharmacokinetics of dexamethasone and methylprednisolone*.

Published in:

Clinical Pharmacology & Therapeutics, 2003, v. 74, n. 1, p. 17, doi. 10.1016/S0009-9236(03)00066-3

By:

McCrea, Jacqueline B.;
Majumdar, Anup K.;
Goldberg, Michael R.;
Iwamoto, Marian;
Gargano, Cynthia;
Panebianco, Deborah L.;
Hesney, Michael;
Lines, Christopher R.;
Petty, Kevin J.;
Deutsch, Paul J.;
Murphy, M. Gail;
Gottesdiener, Keith M.;
Goldwater, D. Ronald;
Blum, Robert A.

Publication type:

Article

Phenotypic and genotypic investigations of a healthy volunteer deficient in the conversion of losartan to its active metabolite E-3174*.

Published in:

Clinical Pharmacology & Therapeutics, 1999, v. 65, n. 3, p. 348, doi. 10.1016/S0009-9236(99)70114-1

By:

McCrea, Jacqueline B.;
Cribb, Alastair;
Rushmore, Tom;
Osborne, Barbara;
Gillen, Lisa;
Lo, Man-Wai;
Waldman, Scott;
Bjornsson, Thorir;
Spielberg, Stephen;
Goldberg, Michael R.

Publication type:

Article

Pharmacokinetics of Atorvastatin and Metformin after Coadministration with Islatravir in Healthy Adults.

Published in:

Journal of Clinical Pharmacology, 2025, v. 65, n. 5, p. 628, doi. 10.1002/jcph.6169

By:

McCrea, Jacqueline B.;
Patel, Munjal;
Liu, Yang;
Vargo, Ryan;
Witter, Rose;
Litovsky, Andrew;
Stoch, S. Aubrey;
Iwamoto, Marian;
Matthews, Randolph P.

Publication type:

Article

Population Pharmacokinetic Analysis of the Cathepsin K Inhibitor Odanacatib: Insights Into Intrinsic and Extrinsic Factor Effects on Exposure in Postmenopausal and Elderly Women.

Published in:

Journal of Clinical Pharmacology, 2020, v. 60, n. 8, p. 1107, doi. 10.1002/jcph.1606

By:

Jaworowicz, David;
Bihorel, Sébastien;
Zajic, Stefan;
Stoch, S. Aubrey;
Humphrey, Rebecca;
McCrea, Jacqueline B.;
Stone, Julie A.

Publication type:

Article

Pharmacokinetic Drug‐Drug Interactions Between Letermovir and the Immunosuppressants Cyclosporine, Tacrolimus, Sirolimus, and Mycophenolate Mofetil.

Published in:

Journal of Clinical Pharmacology, 2019, v. 59, n. 10, p. 1331, doi. 10.1002/jcph.1423

By:

McCrea, Jacqueline B.;
Macha, Sreeraj;
Adedoyin, Adedayo;
Marshall, William;
Menzel, Karsten;
Cho, Carolyn R.;
Liu, Fang;
Zhao, Tian;
Levine, Vanessa;
Kraft, Walter K.;
Yoon, Esther;
Panebianco, Deborah;
Stoch, S. Aubrey;
Iwamoto, Marian

Publication type:

Article

Pharmacogenetic Analysis of OATP1B1, UGT1A1, and BCRP Variants in Relation to the Pharmacokinetics of Letermovir in Previously Conducted Clinical Studies.

Published in:

Journal of Clinical Pharmacology, 2019, v. 59, n. 9, p. 1236, doi. 10.1002/jcph.1420

By:

Kobie, Julie;
Guo, Zifang;
Cho, Carolyn R.;
Menzel, Karsten;
McCrea, Jacqueline B.;
Blanchard, Rebecca;
Shaw, Peter M.

Publication type:

Article

Pharmacokinetics and Tolerability of Letermovir Coadministered With Azole Antifungals (Posaconazole or Voriconazole) in Healthy Subjects.

Published in:

Journal of Clinical Pharmacology, 2018, v. 58, n. 7, p. 897, doi. 10.1002/jcph.1094

By:

Marshall, William L.;
McCrea, Jacqueline B.;
Macha, Sreeraj;
Menzel, Karsten;
Liu, Fang;
van Schanke, Arne;
de Haes, Joanna I. Udo;
Hussaini, Azra;
Jordan, Heather R.;
Drexel, Melissa;
Kantesaria, Bhavna S.;
Tsai, Christine;
Cho, Carolyn R.;
Hulskotte, Ellen G. J.;
Butterton, Joan R.;
Iwamoto, Marian

Publication type:

Article

Single- and Multiple-Dose Pharmacokinetics and Tolerability of Telcagepant, an Oral Calcitonin Gene-Related Peptide Receptor Antagonist, in Adults.

Published in:

Journal of Clinical Pharmacology, 2010, v. 50, n. 12, p. 1367, doi. 10.1177/0091270010361741

By:

Han, Tae H.;
Blanchard, Rebecca L.;
Palcza, John;
McCrea, Jacqueline B.;
Laethem, Tine;
Willson, Kenneth;
Yang Xu;
Ermlich, Susan;
Boyle, Janet;
Lines, Christopher;
Gutierrez, Maria;
Van Bortel, Luc;
Xiao, Alan J.;
Sinclair, Simon;
Hickey, Lisa;
Panebianco, Deborah;
Murphy, M. Gail

Publication type:

Article

In vitro and in vivo characterisation of the metabolism and disposition of suvorexant in humans.

Published in:

Xenobiotica, 2016, v. 46, n. 10, p. 882, doi. 10.3109/00498254.2015.1129565

By:

Cui, Donghui;
Cabalu, Tamara;
Yee, Ka Lai;
Small, James;
Li, Xiaodong;
Liu, Bo;
Maciolek, Cheri;
Smith, Sheri;
Liu, Wen;
McCrea, Jacqueline B.;
Prueksaritanont, Thomayant

Publication type:

Article

Phenobarbital minimally alters plasma concentrations of losartan and its active metabolite E-3174*.

Published in:

Clinical Pharmacology & Therapeutics, 1996, v. 59, n. 3, p. 268, doi. 10.1016/S0009-9236(96)80004-X

By:

Goldberg, Michael R.;
Lo, Man Wai;
Deutsch, Paul J.;
Wilson, Susan E.;
McWilliams, Edward J.;
McCrea, Jacqueline B.

Publication type:

Article

Pharmacokinetics of losartan, an angiotensin II receptor antagonist, and its active metabolite EXP3174 in humans.

Published in:

Clinical Pharmacology & Therapeutics, 1995, v. 58, n. 6, p. 641, doi. 10.1016/0009-9236(95)90020-9

By:

Lo, Man-Wai;
Goldberg, Michael R.;
McCrea, Jacqueline B.;
Lu, Hannah;
Furtek, Christine I.;
Bjornsson, Thorir D.

Publication type:

Article

Works matching AU McCrea, Jacqueline B.

Pharmacokinetics, Safety, and Tolerability of Letermovir Following Single‐ and Multiple‐Dose Administration in Healthy Japanese Subjects.

Drug‐Drug Interaction of Letermovir and Atorvastatin in Healthy Participants.

Assessment of Pharmacokinetic Interaction Between Gefapixant (MK‐7264), a P2X3 Receptor Antagonist, and the OATP1B1 Drug Transporter Substrate Pitavastatin.

Assessment of Pharmacokinetic Interaction Between Letermovir and Fluconazole in Healthy Participants.

Acute and Chronic Effects of Rifampin on Letermovir Suggest Transporter Inhibition and Induction Contribute to Letermovir Pharmacokinetics.

A phase 1 pooled PK/PD analysis of bone resorption biomarkers for odanacatib, a Cathepsin K inhibitor.

Evaluation of the inhibitory effects of itraconazole on letermovir.

A drug–drug interaction study with letermovir and acyclovir in healthy participants.

Clinical and translational pharmacology of the cathepsin K inhibitor odanacatib studied for osteoporosis.

A Single- and Multiple-Dose Study to Evaluate the Pharmacokinetics of Fixed-Dose Grazoprevir/Elbasvir in Healthy Chinese Participants.

Developing a mechanistic understanding of the nonlinear pharmacokinetics of letermovir and prospective drug interaction with everolimus using physiological‐based pharmacokinetic modeling.

Tolerability, pharmacokinetics and night-time effects on postural sway and critical flicker fusion of gaboxadol and zolpidem in elderly subjects.

Repeatability of local forearm vasoconstriction to endothelin-1 measured by venous occlusion plethysmography.

Correction to: Effect of CYP3A Inhibition and Induction on the Pharmacokinetics of Suvorexant: Two Phase I, Open-Label, Fixed-Sequence Trials in Healthy Subjects.

Effect of CYP3A Inhibition and Induction on the Pharmacokinetics of Suvorexant: Two Phase I, Open-Label, Fixed-Sequence Trials in Healthy Subjects.

Indinavir and Rifabutin Drug Interactions in Healthy Volunteers.

Single- and Multiple-Dose Pharmacokinetics of Etoricoxib, a Selective Inhibitor of Cyclooxygenase-2, in Man.

Absence of a Pharmacokinetic Interaction between Losartan and Hydrochlorothiazide.

Lovastatin Does Not Affect Oral Glucose Tolerance in Hypercholesterolemic Patients.

Effects of aprepitant on cytochrome P450 3A4 activity using midazolam as a probe<sup>*</sup>.

Effects of the neurokinin<sub>1</sub> receptor antagonist aprepitant on the pharmacokinetics of dexamethasone and methylprednisolone<sup>*</sup>.

Phenotypic and genotypic investigations of a healthy volunteer deficient in the conversion of losartan to its active metabolite E-3174<sup>*</sup>.

Pharmacokinetics of Atorvastatin and Metformin after Coadministration with Islatravir in Healthy Adults.

Population Pharmacokinetic Analysis of the Cathepsin K Inhibitor Odanacatib: Insights Into Intrinsic and Extrinsic Factor Effects on Exposure in Postmenopausal and Elderly Women.

Pharmacokinetic Drug‐Drug Interactions Between Letermovir and the Immunosuppressants Cyclosporine, Tacrolimus, Sirolimus, and Mycophenolate Mofetil.

Pharmacogenetic Analysis of OATP1B1, UGT1A1, and BCRP Variants in Relation to the Pharmacokinetics of Letermovir in Previously Conducted Clinical Studies.

Pharmacokinetics and Tolerability of Letermovir Coadministered With Azole Antifungals (Posaconazole or Voriconazole) in Healthy Subjects.

Single- and Multiple-Dose Pharmacokinetics and Tolerability of Telcagepant, an Oral Calcitonin Gene-Related Peptide Receptor Antagonist, in Adults.

In vitro and in vivo characterisation of the metabolism and disposition of suvorexant in humans.

Phenobarbital minimally alters plasma concentrations of losartan and its active metabolite E-3174<sup>*</sup>.

Pharmacokinetics of losartan, an angiotensin II receptor antagonist, and its active metabolite EXP3174 in humans.