Works matching AU McClintock, Kevin

Results: 10

Confirming the RNAi-mediated mechanism of action of siRNA-based cancer therapeutics in mice.

Published in:

2009

By:

Judge, Adam D.;
Robbins, Marjorie;
Tavakoli, Iran;
Levi, Jasna;
Hu, Lina;
Fronda, Anna;
Ambegia, Ellen;
McClintock, Kevin;
MacLachian, Ian;
MacLachlan, Ian

Publication type:

journal article

Sequence-dependent stimulation of the mammalian innate immune response by synthetic siRNA.

Published in:

Nature Biotechnology, 2005, v. 23, n. 4, p. 457, doi. 10.1038/nbt1081

By:

Judge, Adam D.;
Sood, Vandana;
Shaw, Janet R.;
Fang, Dianne;
McClintock, Kevin;
MacLachlan, Ian

Publication type:

Article

2′-O-methyl-modified RNAs Act as TLR7 Antagonists.

Published in:

Molecular Therapy, 2007, v. 15, n. 9, p. 1663, doi. 10.1038/sj.mt.6300240

By:

Robbins, Marjorie;
Judge, Adam;
Liang, Lisa;
McClintock, Kevin;
Yaworski, Ed;
MacLachlan, Ian

Publication type:

Article

798. Anti-Influenza-Viral Efficacy Attributed to siRNA Formulated as Simple Lipoplex or PEI Polyplexes Is a Result of Their Immunostimulatory Properties.

Published in:

Molecular Therapy, 2006, v. 13, p. S309, doi. 10.1016/j.ymthe.2006.08.887

By:

Robbins, Marjorie;
Ambegia, Ellen;
Fedoruk, Matthew;
Palmer, Lorne;
McClintock, Kevin;
Judge, Adam;
MacLachlan, Ian

Publication type:

Article

Hypersensitivity and Loss of Disease Site Targeting Caused by Antibody Responses to PEGylated Liposomes.

Published in:

Molecular Therapy, 2006, v. 13, n. 2, p. 328, doi. 10.1016/j.ymthe.2005.09.014

By:

Judge, Adam;
McClintock, Kevin;
Phelps, Janet R.;
MacLachlan, Ian

Publication type:

Article

582. Synthetic siRNA Can Activate the Mammalian Innate Immune Response in a Sequence Dependent Manner

Published in:

2005

By:

Judge, Adam D.;
Shaw, Janet R.;
Sood, Vandana;
McClintock, Kevin;
MacLachlan, Ian

Publication type:

Abstract

ASL mRNA-LNP Therapeutic for the Treatment of Argininosuccinic Aciduria Enables Survival Benefit in a Mouse Model.

Published in:

Biomedicines, 2023, v. 11, n. 6, p. 1735, doi. 10.3390/biomedicines11061735

By:

Daly, Owen;
Mahiny, Azita Josefine;
Majeski, Sara;
McClintock, Kevin;
Reichert, Julia;
Boros, Gábor;
Szabó, Gábor Tamás;
Reinholz, Jonas;
Schreiner, Petra;
Reid, Steve;
Lam, Kieu;
Lepper, Marlen;
Adler, Melanie;
Meffen, Tracy;
Heyes, James;
Karikó, Katalin;
Lutwyche, Pete;
Vlatkovic, Irena

Publication type:

Article

Postexposure Protection of Guinea Pigs against a Lethal Ebola Virus Challenge Is Conferred by RNA Interference.

Published in:

Journal of Infectious Diseases, 2006, v. 193, n. 12, p. 1650, doi. 10.1086/504267

By:

Geisbert, Thomas W.;
Hensley, Lisa E.;
Kagan, Elliott;
Zhaoying Yu, Erik;
Geisbert, Joan B.;
Daddario-DiCaprio, Kathleen;
Fritz, Elizabeth A.;
Jahrling, Peter B.;
McClintock, Kevin;
Phelps, Janet R.;
Lee, Amy C. H.;
Judge, Adam;
Jeffs, Lloyd B.;
MacLachlan, Ian

Publication type:

Article

Unsaturated, Trialkyl Ionizable Lipids are Versatile Lipid‐Nanoparticle Components for Therapeutic and Vaccine Applications.

Published in:

Advanced Materials, 2023, v. 35, n. 15, p. 1, doi. 10.1002/adma.202209624

By:

Lam, Kieu;
Leung, Ada;
Martin, Alan;
Wood, Mark;
Schreiner, Petra;
Palmer, Lorne;
Daly, Owen;
Zhao, Wenchen;
McClintock, Kevin;
Heyes, James

Publication type:

Article

RNAi-mediated gene silencing in non-human primates.

Published in:

2006

By:

Zimmermann, Tracy S.;
Lee, Amy C. H.;
Akinc, Akin;
Bramlage, Birgit;
Bumcrot, David;
Fedoruk, Matthew N.;
Harborth, Jens;
Heyes, James A.;
Jeffs, Lloyd B.;
John, Matthias;
Judge, Adam D.;
Kieu Lam;
McClintock, Kevin;
Nechev, Lubomir V.;
Palmer, Lorne R.;
Racie, Timothy;
Röhl, Ingo;
Seiffert, Stephan;
Shanmugam, Sumi;
Sood, Vandana

Publication type:

Letter