Works matching AU McCaw, Zachary R

Results: 29

DeepNull models non-linear covariate effects to improve phenotypic prediction and association power.

Published in:

Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-021-27930-0

By:

McCaw, Zachary R.;
Colthurst, Thomas;
Yun, Taedong;
Furlotte, Nicholas A.;
Carroll, Andrew;
Alipanahi, Babak;
McLean, Cory Y.;
Hormozdiari, Farhad

Publication type:

Article

Survival Analysis of Treatment Efficacy in Comparative Coronavirus Disease 2019 Studies.

Published in:

Clinical Infectious Diseases, 2021, v. 72, n. 11, p. e887, doi. 10.1093/cid/ciaa1563

By:

McCaw, Zachary R;
Tian, Lu;
Kim, Dae Hyun;
Localio, A Russell;
Wei, Lee-Jen

Publication type:

Article

Fitting Gaussian mixture models on incomplete data.

Published in:

BMC Bioinformatics, 2022, v. 23, n. 1, p. 1, doi. 10.1186/s12859-022-04740-9

By:

McCaw, Zachary R.;
Aschard, Hugues;
Julienne, Hanna

Publication type:

Article

Correction: Fitting Gaussian mixture models on incomplete data.

Published in:

2022

By:

McCaw, Zachary R.;
Aschard, Hugues;
Julienne, Hanna

Publication type:

Correction Notice

Fitting Gaussian mixture models on incomplete data.

Published in:

BMC Bioinformatics, 2022, v. 23, n. 1, p. 1, doi. 10.1186/s12859-022-04740-9

By:

McCaw, Zachary R.;
Aschard, Hugues;
Julienne, Hanna

Publication type:

Article

Fitting Gaussian mixture models on incomplete data.

Published in:

BMC Bioinformatics, 2022, v. 23, n. 1, p. 1, doi. 10.1186/s12859-022-04740-9

By:

McCaw, Zachary R.;
Aschard, Hugues;
Julienne, Hanna

Publication type:

Article

Fitting Gaussian mixture models on incomplete data.

Published in:

BMC Bioinformatics, 2022, v. 23, n. 1, p. 1, doi. 10.1186/s12859-022-04740-9

By:

McCaw, Zachary R.;
Aschard, Hugues;
Julienne, Hanna

Publication type:

Article

Pitfall in the Design and Analysis of Comparative Oncology Trials With a Time-to-Event Endpoint and Recommendations.

Published in:

JNCI Cancer Spectrum, 2022, v. 6, n. 1, p. 1, doi. 10.1093/jncics/pkac007

By:

McCaw, Zachary R;
Kim, Dae Hyun;
Wei, Lee-Jen

Publication type:

Article

Exact Inference for Random Effects Meta-Analyses for Small, Sparse Data.

Published in:

Stats, 2025, v. 8, n. 1, p. 5, doi. 10.3390/stats8010005

By:

Gronsbell, Jessica;
McCaw, Zachary R.;
Regis, Timothy;
Tian, Lu

Publication type:

Article

Justification, margin values, and analysis populations for oncologic noninferiority and equivalence trials: a meta-epidemiological study.

Published in:

JNCI: Journal of the National Cancer Institute, 2025, v. 117, n. 5, p. 898, doi. 10.1093/jnci/djae318

By:

Kleber, Troy J;
Sherry, Alexander D;
Arifin, Andrew J;
Kupferman, Gabrielle S;
Kouzy, Ramez;
Jaoude, Joseph Abi;
Lin, Timothy A;
Beck, Esther J;
Miller, Avital M;
Passy, Adina H;
McCaw, Zachary R;
Msaouel, Pavlos;
Ludmir, Ethan B

Publication type:

Article

How to Quantify and Interpret Treatment Effects in Comparative Clinical Studies of COVID-19.

Published in:

2020

By:

McCaw, Zachary R.;
Tian, Lu;
Vassy, Jason L.;
Ritchie, Christine Seel;
Lee, Chien-Chang;
Kim, Dae Hyun;
Wei, Lee-Jen

Publication type:

journal article

Analysis of Response Data for Assessing Treatment Effects in Comparative Clinical Studies.

Published in:

2020

By:

Huang, Bo;
Tian, Lu;
McCaw, Zachary R.;
Luo, Xiaodong;
Talukder, Enayet;
Rothenberg, Mace;
Xie, Wanling;
Choueiri, Toni K.;
Kim, Dae Hyun;
Wei, Lee-Jen;
Women’s Preventive Services Initiative

Publication type:

journal article

EmbedGEM: a framework to evaluate the utility of embeddings for genetic discovery.

Published in:

Bioinformatics Advances, 2024, v. 4, n. 1, p. 1, doi. 10.1093/bioadv/vbae135

By:

Mukherjee, Sumit;
McCaw, Zachary R;
Pei, Jingwen;
Merkoulovitch, Anna;
Soare, Tom;
Tandon, Raghav;
Amar, David;
Somineni, Hari;
Klein, Christoph;
Satapati, Santhosh;
Lloyd, David;
Probert, Christopher;
Team, Insitro Research;
Koller, Daphne;
O'Dushlaine, Colm;
Karaletsos, Theofanis

Publication type:

Article

Questions About a Risk Prediction Model of Mortality After Esophagectomy for Cancer.

Published in:

2022

By:

McCaw, Zachary R.;
Wei, Lee-Jen

Publication type:

journal article

Quantifying the Added Value of Low-Molecular-Weight Heparin to Intermittent Pneumatic Compression for Preventing Venous Thromboembolic Events Under the Risk-Benefit Perspective.

Published in:

2019

By:

McCaw, Zachary R.;
Piantadosi, Steven;
Wei, Lee-Jen

Publication type:

journal article

Multitrait GWAS to connect disease variants and biological mechanisms.

Published in:

PLoS Genetics, 2021, v. 17, n. 8, p. 1, doi. 10.1371/journal.pgen.1009713

By:

Julienne, Hanna;
Laville, Vincent;
McCaw, Zachary R.;
He, Zihuai;
Guillemot, Vincent;
Lasry, Carla;
Ziyatdinov, Andrey;
Nerin, Cyril;
Vaysse, Amaury;
Lechat, Pierre;
Ménager, Hervé;
Le Goff, Wilfried;
Dube, Marie-Pierre;
Kraft, Peter;
Ionita-Laza, Iuliana;
Vilhjálmsson, Bjarni J.;
Aschard, Hugues

Publication type:

Article

Quantifying the Effect of Lower vs Higher Positive End-Expiratory Pressure on Ventilator-Free Survival in ICU Patients.

Published in:

2021

By:

McCaw, Zachary R.;
Tian, Lu;
Wei, Lee-Jen

Publication type:

Letter

P2Y12 Inhibitor Monotherapy vs Dual Antiplatelet Therapy After Percutaneous Coronary Intervention.

Published in:

JAMA: Journal of the American Medical Association, 2019, v. 322, n. 16, p. 1607, doi. 10.1001/jama.2019.13159

By:

McCaw, Zachary R.;
Wei, Lee-Jen

Publication type:

Article

Analysis of Long-term Benefits of Intensive Blood Pressure Control.

Published in:

2019

By:

McCaw, Zachary R.;
Kim, Dae Hyun;
Wei, Lee-Jen

Publication type:

Letter

Improving the clinical meaning of surrogate endpoints: An empirical assessment of clinical progression in phase III oncology trials.

Published in:

International Journal of Cancer, 2024, v. 155, n. 11, p. 1939, doi. 10.1002/ijc.35129

By:

Sherry, Alexander D.;
Lin, Timothy A.;
McCaw, Zachary R.;
Beck, Esther J.;
Kouzy, Ramez;
Abi Jaoude, Joseph;
Passy, Adina H.;
Miller, Avital M.;
Kupferman, Gabrielle S.;
Fuller, Clifton David;
Thomas, Charles R.;
Koay, Eugene J.;
Tang, Chad;
Msaouel, Pavlos;
Ludmir, Ethan B.

Publication type:

Article

Leveraging a surrogate outcome to improve inference on a partially missing target outcome.

Published in:

Biometrics, 2023, v. 79, n. 2, p. 1472, doi. 10.1111/biom.13629

By:

McCaw, Zachary R.;
Gaynor, Sheila M.;
Sun, Ryan;
Lin, Xihong

Publication type:

Article

Operating characteristics of the rank‐based inverse normal transformation for quantitative trait analysis in genome‐wide association studies.

Published in:

Biometrics, 2020, v. 76, n. 4, p. 1262, doi. 10.1111/biom.13214

By:

McCaw, Zachary R.;
Lane, Jacqueline M.;
Saxena, Richa;
Redline, Susan;
Lin, Xihong

Publication type:

Article

Testing a Large Number of Composite Null Hypotheses Using Conditionally Symmetric Multidimensional Gaussian Mixtures in Genome-Wide Studies.

Published in:

Journal of the American Statistical Association, 2025, v. 120, n. 550, p. 605, doi. 10.1080/01621459.2024.2422124

By:

Sun, Ryan;
McCaw, Zachary R.;
Lin, Xihong

Publication type:

Article

Choosing clinically interpretable summary measures and robust analytic procedures for quantifying the treatment difference in comparative clinical studies.

Published in:

2021

By:

McCaw, Zachary R.;
Lu Tian;
Jiawei Wei;
Lee Claggett, Brian;
Bretz, Frank;
Fitzmaurice, Garrett;
Lee-Jen Wei;
Tian, Lu;
Wei, Jiawei;
Claggett, Brian Lee;
Wei, Lee-Jen

Publication type:

journal article

Differential Treatment Effects of Subgroup Analyses in Phase 3 Oncology Trials From 2004 to 2020.

Published in:

JAMA Network Open, 2024, v. 7, n. 3, p. e243379, doi. 10.1001/jamanetworkopen.2024.3379

By:

Sherry, Alexander D.;
Hahn, Andrew W.;
McCaw, Zachary R.;
Abi Jaoude, Joseph;
Kouzy, Ramez;
Lin, Timothy A.;
Minsky, Bruce;
Fuller, C. David;
Meirson, Tomer;
Msaouel, Pavlos;
Ludmir, Ethan B.

Publication type:

Article

Using a Clinically Interpretable End Point Composed of Multiple Outcomes to Evaluate Totality of Treatment Effect in Comparative Oncology Studies.

Published in:

JAMA Network Open, 2023, v. 6, n. 6, p. e2319055, doi. 10.1001/jamanetworkopen.2023.19055

By:

Wang, Xiaofei;
McCaw, Zachary R.;
Tian, Lu;
Stinchcombe, Thomas E.;
Vokes, Everett;
Ludmir, Ethan B.;
Wei, Lee-Jen

Publication type:

Article

Assessment of Median and Mean Survival Time in Cancer Clinical Trials.

Published in:

JAMA Network Open, 2023, v. 6, n. 4, p. e236498, doi. 10.1001/jamanetworkopen.2023.6498

By:

Das, Ananya;
Lin, Timothy A.;
Lin, Christine;
Meirson, Tomer;
McCaw, Zachary R.;
Tian, Lu;
Ludmir, Ethan B.

Publication type:

Article

Transparency in reporting of phase 3 cancer clinical trial results.

Published in:

Acta Oncologica, 2021, v. 60, n. 2, p. 191, doi. 10.1080/0284186X.2020.1856410

By:

Patel, Roshal R.;
Verma, Vivek;
Fuller, Clifton D.;
McCaw, Zachary R.;
Ludmir, Ethan B.

Publication type:

Article

Genome-wide specificities of CRISPR-Cas Cpf1 nucleases in human cells.

Published in:

Nature Biotechnology, 2016, v. 34, n. 8, p. 869, doi. 10.1038/nbt.3620

By:

Kleinstiver, Benjamin P;
Tsai, Shengdar Q;
Prew, Michelle S;
Nguyen, Nhu T;
Welch, Moira M;
Lopez, Jose M;
McCaw, Zachary R;
Aryee, Martin J;
Joung, J Keith

Publication type:

Article