Works matching AU Maughan, Tim

Results: 35

Image-based consensus molecular subtyping in rectal cancer biopsies and response to neoadjuvant chemoradiotherapy.

Published in:

NPJ Precision Oncology, 2024, v. 8, n. 1, p. 1, doi. 10.1038/s41698-024-00580-3

By:

Lafarge, Maxime W.;
Domingo, Enric;
Sirinukunwattana, Korsuk;
Wood, Ruby;
Samuel, Leslie;
Murray, Graeme;
Richman, Susan D.;
Blake, Andrew;
Sebag-Montefiore, David;
Gollins, Simon;
Klieser, Eckhard;
Neureiter, Daniel;
Huemer, Florian;
Greil, Richard;
Dunne, Philip;
Quirke, Philip;
Weiss, Lukas;
Rittscher, Jens;
Maughan, Tim;
Koelzer, Viktor H.

Publication type:

Article

The "Molecularly Unstratified" Patient: A Focus for Moral, Psycho-Social and Societal Research.

Published in:

Biomedicine Hub, 2017, v. 2, p. 146, doi. 10.1159/000480422

By:

Hordern, Joshua;
Maughan, Tim;
Feiler, Therese;
Morrell, Liz;
Horne, Rob;
Sullivan, Richard

Publication type:

Article

Personalised Medicine: The Promise, the Hype and the Pitfalls.

Published in:

2017

By:

Feiler, Therese;
Gaitskell, Kezia;
Maughan, Tim;
Hordern, Joshua

Publication type:

Editorial

The Promise and the Hype of ‘Personalised Medicine’.

Published in:

New Bioethics, 2017, v. 23, n. 1, p. 13, doi. 10.1080/20502877.2017.1314886

By:

Maughan, Tim

Publication type:

Article

From Rosalind Franklin to Barack Obama: Data Sharing Challenges and Solutions in Genomics and Personalised Medicine.

Published in:

New Bioethics, 2017, v. 23, n. 1, p. 64, doi. 10.1080/20502877.2017.1314883

By:

Lawler, Mark;
Maughan, Tim

Publication type:

Article

Clinical Trial Endpoints in Metastatic Cancer: Using Individual Participant Data to Inform Future Trials Methodology.

Published in:

2022

By:

Goldberg, Richard M;
Adams, Richard;
Buyse, Marc;
Eng, Cathy;
Grothey, Axel;
André, Thierry;
Sobrero, Alberto F;
Lichtman, Stuart M;
Benson, Al B;
Punt, Cornelis J A;
Maughan, Tim;
Burzykowski, Tomasz;
Sommeijer, Dirkje;
Saad, Everardo D;
Shi, Qian;
Coart, Elisabeth;
Chibaudel, Benoist;
Koopman, Miriam;
Schmoll, Hans-Joachim;
Yoshino, Takayuki

Publication type:

journal article

Changing platforms without stopping the train: experiences of data management and data management systems when adapting platform protocols by adding and closing comparisons.

Published in:

2019

By:

Hague, Dominic;
Townsend, Stephen;
Masters, Lindsey;
Rauchenberger, Mary;
Van Looy, Nadine;
Diaz-Montana, Carlos;
Gannon, Melissa;
James, Nicholas;
Maughan, Tim;
Parmar, Mahesh K. B.;
Brown, Louise;
Sydes, Matthew R.;
STAMPEDE and FOCUS4 investigators

Publication type:

journal article

This is a platform alteration: a trial management perspective on the operational aspects of adaptive and platform and umbrella protocols.

Published in:

2019

By:

Schiavone, Francesca;
Bathia, Riya;
Letchemanan, Krishna;
Masters, Lindsey;
Amos, Claire;
Bara, Anna;
Brown, Louise;
Gilson, Clare;
Pugh, Cheryl;
Atako, Nafisah;
Hudson, Fleur;
Parmar, Mahesh;
Langley, Ruth;
Kaplan, Richard S.;
Parker, Chris;
Attard, Gert;
Clarke, Noel W.;
Gillessen, Silke;
James, Nicholas D.;
Maughan, Tim

Publication type:

journal article

A phase 1 trial of the safety, tolerability and biological effects of intravenous Enadenotucirev, a novel oncolytic virus, in combination with chemoradiotherapy in locally advanced rectal cancer (CEDAR).

Published in:

2020

By:

O'Cathail, Séan M.;
Davis, Steven;
Holmes, Jane;
Brown, Richard;
Fisher, Kerry;
Seymour, Leonard;
Adams, Richard;
Good, James;
Sebag-Montefiore, David;
Maughan, Tim;
Hawkins, Maria A.

Publication type:

journal article

Cetuximab therapy in first-line metastatic colorectal cancer and intermittent palliative chemotherapy: review of the COIN trial.

Published in:

Expert Review of Anticancer Therapy, 2008, v. 8, n. 8, p. 1237, doi. 10.1586/14737140.8.8.1237

By:

Adams, Richard;
Meade, Angela;
Wasan, Harpreet;
Griffiths, Gareth;
Maughan, Tim

Publication type:

Article

Predicting response to epidermal growth factor receptor-targeted therapy in colorectal cancer.

Published in:

Expert Review of Anticancer Therapy, 2007, v. 7, n. 4, p. 503, doi. 10.1586/14737140.7.4.503

By:

Adams, Richard;
Maughan, Tim

Publication type:

Article

Figitumumab in patients with refractory metastatic colorectal cancer previously treated with standard therapies: a nonrandomized, open-label, phase II trial.

Published in:

Cancer Chemotherapy & Pharmacology, 2014, v. 73, n. 4, p. 695, doi. 10.1007/s00280-014-2391-2

By:

Becerra, Carlos;
Salazar, Ramon;
Garcia-Carbonero, Rocio;
Thomas, Anne;
Vázquez-Mazón, Federico;
Cassidy, James;
Maughan, Tim;
Castillo, Manuel;
Iveson, Tim;
Yin, Donghua;
Green, Stephanie;
Bergsland, Emily

Publication type:

Article

Impact of geography on prognostic outcomes of 21,509 patients with metastatic colorectal cancer enrolled in clinical trials: an ARCAD database analysis.

Published in:

Therapeutic Advances in Medical Oncology, 2021, p. 1, doi. 10.1177/17588359211020547

By:

Yin, Jun;
Dawood, Shaheenah;
Cohen, Romain;
Meyers, Jeff;
Zalcberg, John;
Yoshino, Takayuki;
Seymour, Matthew;
Maughan, Tim;
Saltz, Leonard;
Van Cutsem, Eric;
Venook, Alan;
Schmoll, Hans-Joachim;
Goldberg, Richard;
Hoff, Paulo;
Hecht, J. Randolph;
Hurwitz, Herbert;
Punt, Cornelis;
Diaz Rubio, Eduard;
Koopman, Miriam;
Cremolini, Chiara

Publication type:

Article

The management of skin reactions in cancer patients receiving epidermal growth factor receptor targeted therapies.

Published in:

Journal der Deutschen Dermatologischen Gesellschaft, 2005, v. 3, n. 8, p. 599, doi. 10.1111/j.1610-0387.2005.05058.x

By:

Segaert, Siegfried;
Tabernero, Josep;
Chosidow, Olivier;
Dirschka, Thomas;
Elsner, Joern;
Mancini, Luca;
Maughan, Tim;
Morere, Jean-Franµois;
Santoro, Armando;
Sobrero, Alberto;
Van Cutsem, Eric;
Layton, Alison

Publication type:

Article

Stromal composition predicts recurrence of early rectal cancer after local excision.

Published in:

Histopathology, 2021, v. 79, n. 6, p. 947, doi. 10.1111/his.14438

By:

Jones, Helen J S;
Cunningham, Chris;
Askautrud, Hanne A;
Danielsen, Håvard E;
Kerr, David J;
Domingo, Enric;
Maughan, Tim;
Leedham, Simon J;
Koelzer, Viktor H

Publication type:

Article

Changing the Paradigm--Multistage Multiarm Randomized Trials and Stratified Cancer Medicine.

Published in:

2015

By:

Lawler, Mark;
Kaplan, Rick;
Wilson, Richard H.;
Maughan, Tim

Publication type:

Editorial

New role of fat-free mass in cancer risk linked with genetic predisposition.

Published in:

Scientific Reports, 2024, v. 14, n. 1, p. 1, doi. 10.1038/s41598-024-54291-7

By:

Harris, Benjamin H. L.;
Di Giovannantonio, Matteo;
Zhang, Ping;
Harris, David A.;
Lord, Simon R.;
Allen, Naomi E.;
Maughan, Tim S.;
Bryant, Richard J.;
Harris, Adrian L.;
Bond, Gareth L.;
Buffa, Francesca M.

Publication type:

Article

Global colorectal cancer research, 2007‐2021: Outputs and funding.

Published in:

International Journal of Cancer, 2023, v. 152, n. 3, p. 470, doi. 10.1002/ijc.34279

By:

Begum, Mursheda;
Lewison, Grant;
Wang, Xiang;
Dunne, Philip D.;
Maughan, Tim;
Sullivan, Richard;
Lawler, Mark

Publication type:

Article

Youth Culture and the Making of the Post--Fordist Economy: Dance Music in Contemporary Britain.

Published in:

Journal of Youth Studies, 1998, v. 1, n. 2, p. 211, doi. 10.1080/13676261.1998.10593007

By:

Smith, Richard J.;
Maughan, Tim

Publication type:

Article

Cancer-cell intrinsic gene expression signatures overcome intratumoural heterogeneity bias in colorectal cancer patient classification.

Published in:

Nature Communications, 2017, v. 8, n. 5, p. 15657, doi. 10.1038/ncomms15657

By:

Dunne, Philip D.;
Alderdice, Matthew;
O'Reilly, Paul G.;
Roddy, Aideen C.;
McCorry, Amy M. B.;
Richman, Susan;
Maughan, Tim;
McDade, Simon S.;
Johnston, Patrick G.;
Longley, Daniel B.;
Kay, Elaine;
McArt, Darragh G.;
Lawler, Mark

Publication type:

Article

Impact of geography on prognostic outcomes of 21,509 patients with metastatic colorectal cancer enrolled in clinical trials: an ARCAD database analysis.

Published in:

Therapeutic Advances in Medical Oncology, 2021, p. 1, doi. 10.1177/17588359211020547

By:

Yin, Jun;
Dawood, Shaheenah;
Cohen, Romain;
Meyers, Jeff;
Zalcberg, John;
Yoshino, Takayuki;
Seymour, Matthew;
Maughan, Tim;
Saltz, Leonard;
Van Cutsem, Eric;
Venook, Alan;
Schmoll, Hans-Joachim;
Goldberg, Richard;
Hoff, Paulo;
Hecht, J. Randolph;
Hurwitz, Herbert;
Punt, Cornelis;
Diaz Rubio, Eduard;
Koopman, Miriam;
Cremolini, Chiara

Publication type:

Article

Prospective patient stratification into robust cancer‐cell intrinsic subtypes from colorectal cancer biopsies.

Published in:

Journal of Pathology, 2018, v. 245, n. 1, p. 19, doi. 10.1002/path.5051

By:

Alderdice, Matthew;
Richman, Susan D.;
Gollins, Simon;
Stewart, James P.;
Hurt, Chris;
Adams, Richard;
McCorry, Amy M. B.;
Roddy, Aideen C.;
Vimalachandran, Dale;
Isella, Claudio;
Medico, Enzo;
Maughan, Tim;
McArt, Darragh G.;
Lawler, Mark;
Dunne, Philip D.

Publication type:

Article

No One's Driving: Autonomous Vehicles Will Reshape Cities, but is Anyone Taking Control of How?

Published in:

Architectural Design, 2019, v. 89, n. 1, p. 92, doi. 10.1002/ad.2395

By:

Maughan, Tim

Publication type:

Article

Media Network: Three Moments From the Future Post-Manufacturing Supply Chain.

Published in:

Architectural Design, 2015, v. 85, n. 4, p. 88, doi. 10.1002/ad.1932

By:

Maughan, Tim;
Young, Liam

Publication type:

Article

Molecular subtype-specific efficacy of anti-EGFR therapy in colorectal cancer is dependent on the chemotherapy backbone.

Published in:

2021

By:

ten Hoorn, Sanne;
Sommeijer, Dirkje W.;
Elliott, Faye;
Fisher, David;
de Back, Tim R.;
Trinh, Anne;
Koens, Lianne;
Maughan, Tim;
Seligmann, Jenny;
Seymour, Matthew T.;
Quirke, Phil;
Adams, Richard;
Richman, Susan D.;
Punt, Cornelis J. A.;
Vermeulen, Louis

Publication type:

journal article

Lack of an association between gallstone disease and bilirubin levels with risk of colorectal cancer: a Mendelian randomisation analysis.

Published in:

2021

By:

Culliford, Richard;
Cornish, Alex J.;
Law, Philip J.;
Farrington, Susan M.;
Palin, Kimmo;
Jenkins, Mark A.;
Casey, Graham;
Hoffmeister, Michael;
Brenner, Hermann;
Chang-Claude, Jenny;
Kirac, Iva;
Maughan, Tim;
Brezina, Stefanie;
Gsur, Andrea;
Cheadle, Jeremy P.;
Aaltonen, Lauri A.;
Dunlop, Malcom G.;
Houlston, Richard S.

Publication type:

journal article

Circulating biomarkers and outcomes from a randomised phase 2 trial of gemcitabine versus capecitabine-based chemoradiotherapy for pancreatic cancer.

Published in:

2021

By:

Willenbrock, Frances;
Cox, Catrin M.;
Parkes, Eileen E.;
Wilhelm-Benartzi, Charlotte S.;
Abraham, Aswin G.;
Owens, Robert;
Sabbagh, Ahmad;
Jones, Christopher M.;
Hughes, Daniel L. I.;
Maughan, Tim;
Hurt, Christopher N.;
O'Neill, Eric E.;
Mukherjee, Somnath

Publication type:

journal article

A prospective phase II study of pre-operative chemotherapy then short-course radiotherapy for high risk rectal cancer: COPERNICUS.

Published in:

2018

By:

Gollins, Simon;
West, Nicholas;
Sebag-Montefiore, David;
Susnerwala, Shabbir;
Falk, Stephen;
Brown, Nick;
Saunders, Mark;
Quirke, Philip;
Ray, Ruby;
Parsons, Philip;
Griffiths, Gareth;
Maughan, Tim;
Adams, Richard;
Hurt, Chris

Publication type:

journal article

[F]Fluoromisonidazole PET in rectal cancer.

Published in:

EJNMMI Research, 2017, v. 7, n. 1, p. 1, doi. 10.1186/s13550-017-0324-x

By:

Puri, Tanuj;
Greenhalgh, Tessa;
Wilson, James;
Franklin, Jamie;
Wang, Lia;
Strauss, Victoria;
Cunningham, Chris;
Partridge, Mike;
Maughan, Tim

Publication type:

Article

Guidelines for using sigQC for systematic evaluation of gene signatures.

Published in:

Nature Protocols, 2019, v. 14, n. 5, p. 1377, doi. 10.1038/s41596-019-0136-8

By:

Dhawan, Andrew;
Barberis, Alessandro;
Cheng, Wei-Chen;
Domingo, Enric;
West, Catharine;
Maughan, Tim;
Scott, Jacob G.;
Harris, Adrian L.;
Buffa, Francesca M.

Publication type:

Article

The clinical impact of expert pathological review on lymphoma management: a regional experience.

Published in:

British Journal of Haematology, 2003, v. 123, n. 3, p. 463, doi. 10.1046/j.1365-2141.2003.04629.x

By:

Lester, Jason F.;
Dojcinov, Stefan D.;
Attanoos, Richard L.;
O'Brien, Ciaran J.;
Maughan, Tim S.;
Toy, Elizabeth T.;
Poynton, Chris H.

Publication type:

Article

NRF2 Mediates Therapeutic Resistance to Chemoradiation in Colorectal Cancer through a Metabolic Switch.

Published in:

Antioxidants, 2021, v. 10, n. 9, p. 1380, doi. 10.3390/antiox10091380

By:

O'Cathail, Séan M.;
Wu, Chieh-Hsi;
Thomas, Rachael;
Hawkins, Maria A.;
Maughan, Tim S.;
Lewis, Annabelle

Publication type:

Article

Prognostic significance of hypoxia inducible factor-1α and vascular endothelial growth factor expression in patients with diffuse large B-cell lymphoma treated with rituximab.

Published in:

Leukemia & Lymphoma, 2013, v. 54, n. 5, p. 959, doi. 10.3109/10428194.2012.733875

By:

Powell, James R.;
Dojcinov, Stefan;
King, Louise;
Wosniak, Sue;
Gerry, Stephen;
Casbard, Angela;
Bailey, Hazel;
Gallop-Evans, Eve;
Maughan, Tim

Publication type:

Article

Derived neutrophil lymphocyte ratio is predictive of survival from intermittent therapy in advanced colorectal cancer: a post hoc analysis of the MRC COIN study.

Published in:

2016

By:

Grenader, Tal;
Nash, Stephen;
Adams, Richard;
Kaplan, Richard;
Fisher, David;
Maughan, Tim;
Bridgewater, John

Publication type:

journal article

A phase II open label, randomised study of ipilimumab with temozolomide versus temozolomide alone after surgery and chemoradiotherapy in patients with recently diagnosed glioblastoma: the Ipi-Glio trial protocol.

Published in:

2020

By:

Brown, Nicholas F.;
Ng, Stasya M.;
Brooks, Claire;
Coutts, Tim;
Holmes, Jane;
Roberts, Corran;
Elhussein, Leena;
Hoskin, Peter;
Maughan, Tim;
Blagden, Sarah;
Mulholland, Paul

Publication type:

journal article