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Extracellular release of two peptidases dominates generation of the trypanosome quorum-sensing signal.
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- Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-31057-1
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- Article
Basement membrane proteins as a substrate for efficient Trypanosoma brucei differentiation in vitro.
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- PLoS Neglected Tropical Diseases, 2021, v. 15, n. 4, p. 1, doi. 10.1371/journal.pntd.0009284
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- Article
Investigating Mammalian Tyrosine Phosphatase Inhibitors as Potential 'Piggyback' Leads to Target Trypanosoma brucei Transmission.
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- Chemical Biology & Drug Design, 2013, v. 81, n. 2, p. 291, doi. 10.1111/cbdd.12079
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- Article
A novel CCCH protein which modulates differentiation of Trypanosoma brucei to its procyclic form.
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- EMBO Journal, 2001, v. 20, n. 23, p. 6700, doi. 10.1093/emboj/20.23.6700
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- Article
A conserved trypanosomatid differentiation regulator controls substrate attachment and morphological development in Trypanosoma congolense.
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- PLoS Pathogens, 2024, v. 20, n. 2, p. 1, doi. 10.1371/journal.ppat.1011889
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- Article
Bloodstream form pre-adaptation to the tsetse fly in Trypanosoma brucei.
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- Frontiers in Cellular & Infection Microbiology, 2013, v. 3, p. 1, doi. 10.3389/fcimb.2013.00078
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- Article
NMD3 regulates both mRNA and rRNA nuclear export in African trypanosomes via an XPOI-linked pathway.
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- Nucleic Acids Research, 2015, v. 43, n. 9, p. 4491, doi. 10.1093/nar/gkv330
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- Article
Identification of the regulatory elements controlling the transmission stage-specific gene expression of PAD1 in Trypanosoma brucei.
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- Nucleic Acids Research, 2012, v. 40, n. 16, p. 7705, doi. 10.1093/nar/gks533
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- Article
The post-transcriptional trans-acting regulator, TbZFP3, co-ordinates transmission-stage enriched mRNAs in Trypanosoma brucei.
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- Nucleic Acids Research, 2012, v. 40, n. 7, p. 2869, doi. 10.1093/nar/gkr1106
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- Article
Single-cell transcriptomic analysis of bloodstream Trypanosoma brucei reconstructs cell cycle progression and developmental quorum sensing.
- Published in:
- Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-25607-2
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- Article
Harnessing evolutionary biology to combat infectious disease.
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- 2012
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- Publication type:
- Opinion
Targeting pathogen metabolism without collateral damage to the host.
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- Scientific Reports, 2017, p. 40406, doi. 10.1038/srep40406
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- Article
Disruption of the developmental programme of Trypanosoma brucei by genetic ablation of TbZFP1, a differentiation-enriched CCCH protein.
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- Molecular Microbiology, 2005, v. 57, n. 3, p. 706, doi. 10.1111/j.1365-2958.2005.04679.x
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- Article
Differentiation granules, a dynamic regulator of T. brucei development.
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- Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-47309-1
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- Article
Regulation of <i>Trypanosoma brucei</i> Total and Polysomal mRNA during Development within Its Mammalian Host.
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- PLoS ONE, 2013, v. 8, n. 6, p. 1, doi. 10.1371/journal.pone.0067069
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- Article
The Trypanosome Rab-Related Proteins RabX1 and RabX2 Play No Role in IntraCellular Trafficking but May Be Involved in Fly Infectivity.
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- PLoS ONE, 2009, v. 4, n. 9, p. 1, doi. 10.1371/journal.pone.0007217
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- Article
New discoveries in the transmission biology of sleeping sickness parasites: applying the basics.
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- Journal of Molecular Medicine, 2010, v. 88, n. 9, p. 865, doi. 10.1007/s00109-010-0637-y
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- Article
Comment on 'Unexpected plasticity in the life cycle of Trypanosoma brucei'.
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- eLife, 2022, p. 1, doi. 10.7554/eLife.74985
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- Article
Assembling the components of the quorum sensing pathway in African trypanosomes.
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- Molecular Microbiology, 2015, v. 96, n. 2, p. 220, doi. 10.1111/mmi.12949
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- Article
A gene expression comparison of Trypanosoma brucei and Trypanosoma congolense in the bloodstream of the mammalian host reveals species-specific adaptations to density-dependent development.
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- PLoS Neglected Tropical Diseases, 2018, v. 12, n. 10, p. 1, doi. 10.1371/journal.pntd.0006863
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- Article
Mitochondrial DNA is critical for longevity and metabolism of transmission stage Trypanosoma brucei.
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- PLoS Pathogens, 2018, v. 14, n. 7, p. 1, doi. 10.1371/journal.ppat.1007195
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- Article
Non-linear hierarchy of the quorum sensing signalling pathway in bloodstream form African trypanosomes.
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- PLoS Pathogens, 2018, v. 14, n. 6, p. 1, doi. 10.1371/journal.ppat.1007145
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- Article
A surface transporter family conveys the trypanosome differentiation signal.
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- Nature, 2009, v. 459, n. 7244, p. 213, doi. 10.1038/nature07997
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- Article
The Cytological Events and Molecular Control of Life Cycle Development of Trypanosoma brucei in the Mammalian Bloodstream.
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- Pathogens, 2017, v. 6, n. 3, p. 29, doi. 10.3390/pathogens6030029
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- Article
Independent Pathways Can Transduce the Life-Cycle Differentiation Signal in <i>Trypanosoma brucei</i>.
- Published in:
- PLoS Pathogens, 2013, v. 9, n. 10, p. 1, doi. 10.1371/journal.ppat.1003689
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- Article
Targeting Cattle-Borne Zoonoses and Cattle Pathogens Using a Novel Trypanosomatid-Based Delivery System.
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- PLoS Pathogens, 2011, v. 7, n. 10, p. 1, doi. 10.1371/journal.ppat.1002340
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- Article
Differential Trypanosome Surface Coat Regulation by a CCCH Protein That Co-Associates with procyclin mRNA cis-Elements.
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- PLoS Pathogens, 2009, v. 5, n. 2, p. 1, doi. 10.1371/journal.ppat.1000317
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- Article
Protein tyrosine phosphatase TbPTP1: a molecular switch controlling life cycle differentiation in trypanosomes.
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- Journal of Cell Biology, 2006, v. 175, n. 2, p. 293
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- Article
Profiling the bloodstream form and procyclic form Trypanosoma brucei cell cycle using single-cell transcriptomics.
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- eLife, 2023, p. 1, doi. 10.7554/eLife.86325
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- Article
The SPARC complex defines RNAPII promoters in Trypanosoma brucei.
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- eLife, 2022, p. 1, doi. 10.7554/eLife.83135
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- Article
ON THE OPTIMAL CONTINUED FRACTION EXPANSION OF A QUADRATIC SURD.
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- Journal of the Australian Mathematical Society, 2012, v. 93, n. 1/2, p. 133, doi. 10.1017/S1446788712000596
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- Article
African trypanosomes.
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- Parasites & Vectors, 2019, v. 12, n. 1, p. N.PAG, doi. 10.1186/s13071-019-3355-5
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- Article
Genome-wide RNAi selection identifies a regulator of transmission stage-enriched gene families and cell-type differentiation in Trypanosoma brucei.
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- PLoS Pathogens, 2017, v. 13, n. 3, p. 1, doi. 10.1371/journal.ppat.1006279
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- Article
Trypanosomal immune evasion, chronicity and transmission: an elegant balancing act.
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- Nature Reviews Microbiology, 2012, v. 10, n. 6, p. 431, doi. 10.1038/nrmicro2779
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- Article
Consistent detection of Trypanosoma brucei but not T. congolense DNA in faeces of experimentally infected cattle.
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- Scientific Reports, 2024, v. 14, n. 1, p. 1, doi. 10.1038/s41598-024-54857-5
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- Article