Works by Matthew A. Perugini

Results: 38

Polymerase delta-interacting protein 38 (PDIP38) modulates the stability and activity of the mitochondrial AAA+ protease CLPXP.

Published in:

Communications Biology, 2020, v. 3, n. 1, p. N.PAG, doi. 10.1038/s42003-020-01358-6

By:

Strack, Philip R.;
Brodie, Erica J.;
Zhan, Hanmiao;
Schuenemann, Verena J.;
Valente, Liz J.;
Saiyed, Tamanna;
Lowth, Bradley R.;
Angley, Lauren M.;
Perugini, Matthew A.;
Zeth, Kornelius;
Truscott, Kaye N.;
Dougan, David A.

Publication type:

Article

The oligomeric assembly of galectin-11 is critical for anti-parasitic activity in sheep (Ovis aries).

Published in:

Communications Biology, 2020, v. 3, n. 1, p. N.PAG, doi. 10.1038/s42003-020-01179-7

By:

Sakthivel, Dhanasekaran;
Preston, Sarah;
Gasser, Robin B.;
Costa, Tatiana P. Soares da;
Hernandez, Julia N.;
Shahine, Adam;
Shakif-Azam, M. D.;
Lock, Peter;
Rossjohn, Jamie;
Perugini, Matthew A.;
González, Jorge Francisco;
Meeusen, Els;
Piedrafita, David;
Beddoe, Travis

Publication type:

Article

A partially structured region of a largely unstructured protein, Plasmodium falciparum merozoite surface protein 2 (MSP2), forms amyloid-like fibrils.

Published in:

Journal of Peptide Science, 2007, v. 13, n. 12, p. 839, doi. 10.1002/psc.910

By:

Yang, Xiaodong;
Adda, Christopher G.;
Keizer, David W.;
Murphy, Vince J.;
Rizkalla, Michael M.;
Perugini, Matthew A.;
Jackson, David C.;
Anders, Robin F.;
Norton, Raymond S.

Publication type:

Article

Mis‐annotations of a promising antibiotic target in high‐priority gram‐negative pathogens.

Published in:

FEBS Letters, 2020, v. 594, n. 9, p. 1453, doi. 10.1002/1873-3468.13733

By:

Impey, Rachael E.;
Lee, Mihwa;
Hawkins, Daniel A.;
Sutton, J. Mark;
Panjikar, Santosh;
Perugini, Matthew A.;
Soares da Costa, Tatiana P.

Publication type:

Article

An intact membrane is essential for small extracellular vesicle‐induced modulation of α‐synuclein fibrillization.

Published in:

Journal of Extracellular Vesicles, 2020, v. 10, n. 2, p. 1, doi. 10.1002/jev2.12034

By:

Ugalde, Cathryn L.;
Gordon, Shane E.;
Shambrook, Mitch;
Nasiri Kenari, Amirmohammad;
Coleman, Bradley M.;
Perugini, Matthew A.;
Lawson, Victoria A.;
Finkelstein, David I.;
Hill, Andrew F.

Publication type:

Article

Towards novel herbicide modes of action by inhibiting lysine biosynthesis in plants.

Published in:

eLife, 2021, p. 1, doi. 10.7554/eLife.69444

By:

Soares da Costa, Tatiana P.;
Hall, Cody J.;
Panjikar, Santosh;
Wyllie, Jessica A.;
Christoff, Rebecca M.;
Bayat, Saadi;
Hulett, Mark D.;
Abbott, Belinda M.;
Gendall, Anthony R.;
Perugini, Matthew A.

Publication type:

Article

Structural insights into BCL2 pro-survival protein interactions with the key autophagy regulator BECN1 following phosphorylation by STK4/MST1.

Published in:

Autophagy, 2019, v. 15, n. 5, p. 785, doi. 10.1080/15548627.2018.1564557

By:

Lee, Erinna F.;
Smith, Nicholas A.;
Soares da Costa, Tatiana P.;
Meftahi, Nastaran;
Yao, Shenggen;
Harris, Tiffany J.;
Tran, Sharon;
Pettikiriarachchi, Anne;
Perugini, Matthew A.;
Keizer, David W.;
Evangelista, Marco;
Smith, Brian J.;
Fairlie, W. Douglas

Publication type:

Article

Crystal structure of the Leishmania major MIX protein: A scaffold protein that mediates protein-protein interactions.

Published in:

Protein Science: A Publication of the Protein Society, 2011, v. 20, n. 6, p. 1060, doi. 10.1002/pro.631

By:

Gorman, Michael A.;
Uboldi, Alex D.;
Walsh, Peter J.;
Tan, Kher Shing;
Hansen, Guido;
Huyton, Trevor;
Ji, Hong;
Curtis, Joan;
Kedzierski, Lukasz;
Papenfuss, Anthony T.;
Dogovski, Con;
Perugini, Matthew A.;
Simpson, Richard J.;
Handman, Emanuela;
Parker, Michael W.

Publication type:

Article

Conserved main-chain peptide distortions: A proposed role for Ile203 in catalysis by dihydrodipicolinate synthase.

Published in:

Protein Science: A Publication of the Protein Society, 2008, v. 17, n. 12, p. 2080, doi. 10.1110/ps.037440.108

By:

Dobson, Renwick C.J.;
Griffin, Michael D.W.;
Devenish, Sean R.A.;
Pearce, F. Grant;
Hutton, Craig A.;
Gerrard, Juliet A.;
Jameson, Geoffrey B.;
Perugini, Matthew A.

Publication type:

Article

Size matters! Fragmentation chemistry of [Cu(L)n]2+ complexes of diacylglycerophosphocholines as a function of coordination number (n = 2-7).

Published in:

Rapid Communications in Mass Spectrometry: RCM, 2007, v. 21, n. 5, p. 757, doi. 10.1002/rcm.2891

By:

James, Patrick F.;
Perugini, Matthew A.;
O'Hair, Richard A. J.

Publication type:

Article

Identification of a dimeric KDG aldolase from Agrobacterium tumefaciens.

Published in:

Proteins, 2017, v. 85, n. 11, p. 2058, doi. 10.1002/prot.25359

By:

Soares da Costa, Tatiana P.;
Patel, Madhvi;
Desbois, Sebastien;
Gupta, Ruchi;
Faou, Pierre;
Perugini, Matthew A.

Publication type:

Article

Identification of the bona fide DHDPS from a common plant pathogen.

Published in:

Proteins, 2014, v. 82, n. 9, p. 1869, doi. 10.1002/prot.24539

By:

Atkinson, Sarah C.;
Hor, Lilian;
Dogovski, Con;
Dobson, Renwick C. J.;
Perugini, Matthew A.

Publication type:

Article

A Family of Helminth Molecules that Modulate Innate Cell Responses via Molecular Mimicry of Host Antimicrobial Peptides.

Published in:

PLoS Pathogens, 2011, v. 7, n. 5, p. 1, doi. 10.1371/journal.ppat.1002042

By:

Robinson, Mark W.;
Donnelly, Sheila;
Hutchinson, Andrew T.;
To, Joyce;
Taylor, Nicole L.;
Norton, Raymond S.;
Perugini, Matthew A.;
Dalton, John P.

Publication type:

Article

Targeting of a natural killer cell receptor family by a viral immunoevasin.

Published in:

Nature Immunology, 2013, v. 14, n. 7, p. 699, doi. 10.1038/ni.2605

By:

Berry, Richard;
Ng, Natasha;
Saunders, Philippa M;
Vivian, Julian P;
Lin, Jie;
Deuss, Felix A;
Corbett, Alexandra J;
Forbes, Catherine A;
Widjaja, Jacqueline M;
Sullivan, Lucy C;
McAlister, Adrian D;
Perugini, Matthew A;
Call, Melissa J;
Scalzo, Anthony A;
Degli-Esposti, Mariapia A;
Coudert, Jerome D;
Beddoe, Travis;
Brooks, Andrew G;
Rossjohn, Jamie

Publication type:

Article

Integrated activities of two alternative sigma factors coordinate iron acquisition and uptake by Pseudomonas aeruginosa.

Published in:

Molecular Microbiology, 2017, v. 106, n. 6, p. 891, doi. 10.1111/mmi.13855

By:

Edgar, Rebecca J.;
Hampton, Georgina E.;
Garcia, G. Patricia Casas;
Maher, Megan J.;
Perugini, Matthew A.;
Ackerley, David F.;
Lamont, Iain L.

Publication type:

Article

Dual roles of F123 in protein homodimerization and inhibitor binding to biotin protein ligase from Staphylococcus aureus.

Published in:

Molecular Microbiology, 2014, v. 91, n. 1, p. 110, doi. 10.1111/mmi.12446

By:

Soares da Costa, Tatiana P.;
Yap, Min Y.;
Perugini, Matthew A.;
Wallace, John C.;
Abell, Andrew D.;
Wilce, Matthew C. J.;
Polyak, Steven W.;
Booker, Grant W.

Publication type:

Article

The BECN1 N-terminal domain is intrinsically disordered.

Published in:

Autophagy, 2016, v. 12, n. 3, p. 460, doi. 10.1080/15548627.2016.1140292

By:

Lee, Erinna F.;
Perugini, Matthew A.;
Pettikiriarachchi, Anne;
Evangelista, Marco;
Keizer, David W.;
Yao, Shenggen;
Fairlie, W. Douglas

Publication type:

Article

Dynamic Modelling Reveals ‘Hotspots’ on the Pathway to Enzyme-Substrate Complex Formation.

Published in:

PLoS Computational Biology, 2016, v. 12, n. 3, p. 1, doi. 10.1371/journal.pcbi.1004811

By:

Gordon, Shane E.;
Weber, Daniel K.;
Downton, Matthew T.;
Wagner, John;
Perugini, Matthew A.

Publication type:

Article

Shark Variable New Antigen Receptor (VNAR) Single Domain Antibody Fragments: Stability and Diagnostic Applications.

Published in:

Antibodies (2073-4468), 2013, v. 2, n. 1, p. 66, doi. 10.3390/antib2010066

By:

Griffiths, Katherine;
Dolezal, Olan;
Parisi, Kathy;
Angerosa, Julie;
Dogovski, Con;
Barraclough, Miles;
Sanalla, Abdulmonem;
Casey, Joanne L.;
González, Iveth;
Perugini, Matthew A.;
Nuttall, Stewart;
Foley, Michael

Publication type:

Article

Defining the interaction of perforin with calcium and the phospholipid membrane.

Published in:

Biochemical Journal, 2013, v. 456, n. 3, p. 323, doi. 10.1042/BJ20130999

By:

TRAORE, Daouda A. K.;
BRENNAN, Amelia J.;
LAW, Ruby H. P.;
DOGOVSKI, Con;
PERUGINI, Matthew A.;
LUKOYANOVA, Natalya;
LEUNG, Eleanor W. W.;
NORTON, Raymond S.;
LOPEZ, Jamie A.;
BROWNE, Kylie A.;
YAGITA, Hideo;
LLOYD, Gordon J.;
CICCONE, Annette;
VERSCHOOR, Sandra;
TRAPANI, Joseph A.;
WHISSTOCK, James C.;
VOSKOBOINIK, Ilia

Publication type:

Article

Review: amino acid biosynthesis as a target for herbicide development.

Published in:

Pest Management Science, 2020, v. 76, n. 12, p. 3896, doi. 10.1002/ps.5943

By:

Hall, Cody J;
Mackie, Emily RR;
Gendall, Anthony R;
Perugini, Matthew A;
Soares da Costa, Tatiana P

Publication type:

Article

Homodimerization attenuates the anti-inflammatory activity of interleukin-37.

Published in:

Science Immunology, 2017, v. 2, n. 8, p. 1, doi. 10.1126/sciimmunol.aaj1548

By:

Ellisdon, Andrew M.;
Nold-Petry, Claudia A.;
D’Andrea, Laura;
Cho, Steven X.;
Lao, Jason C.;
Rudloff, Ina;
Ngo, Devi;
Lo, Camden Y.;
Soares da Costa, Tatiana P.;
Perugini, Matthew A.;
Conroy, Paul J.;
Whisstock, James C.;
Nold, Marcel F.

Publication type:

Article

New method for purifying histidine-rich glycoprotein from human plasma redefines its functional properties.

Published in:

IUBMB Life, 2013, v. 65, n. 6, p. 550, doi. 10.1002/iub.1168

By:

Patel, Kruti K.;
Poon, Ivan K. H.;
Talbo, Gert H.;
Perugini, Matthew A.;
Taylor, Nicole L.;
Ralph, Troy J.;
Hoogenraad, Nicholas J.;
Hulett, Mark D.

Publication type:

Article

From Knock-Out Phenotype to Three-Dimensional Structure of a Promising Antibiotic Target from Streptococcus pneumoniae.

Published in:

PLoS ONE, 2013, v. 8, n. 12, p. 1, doi. 10.1371/journal.pone.0083419

By:

Dogovski, Con;
Gorman, Michael A.;
Ketaren, Natalia E.;
Praszkier, Judy;
Zammit, Leanne M.;
Mertens, Haydyn D.;
Bryant, Gary;
Yang, Ji;
Griffin, Michael D. W.;
Pearce, F. Grant;
Gerrard, Juliet A.;
Jameson, Geoffrey B.;
Parker, Michael W.;
Robins-Browne, Roy M.;
Perugini, Matthew A.

Publication type:

Article

High-Throughput Screening for Novel Inhibitors of Neisseria gonorrhoeae Penicillin-Binding Protein 2.

Published in:

PLoS ONE, 2012, v. 7, n. 9, p. 1, doi. 10.1371/journal.pone.0044918

By:

Fedarovich, Alena;
Djordjevic, Kevin A.;
Swanson, Shauna M.;
Peterson, Yuri K.;
Nicholas, Robert A.;
Davies, Christopher;
Perugini, Matthew A

Publication type:

Article

Ultramarine, a Chromoprotein Acceptor for Förster Resonance Energy Transfer.

Published in:

PLoS ONE, 2012, v. 7, n. 7, p. 1, doi. 10.1371/journal.pone.0041028

By:

Pettikiriarachchi, Anne;
Gong, Lan;
Perugini, Matthew A.;
Devenish, Rodney J.;
Prescott, Mark

Publication type:

Article

Characterisation of the First Enzymes Committed to Lysine Biosynthesis in Arabidopsis thaliana.

Published in:

PLoS ONE, 2012, v. 7, n. 7, p. 1, doi. 10.1371/journal.pone.0040318

By:

Griffin, Michael D. W.;
Billakanti, Jagan M.;
Wason, Akshita;
Keller, Sabrina;
Mertens, Haydyn D. T.;
Atkinson, Sarah C.;
Dobson, Renwick C. J.;
Perugini, Matthew A.;
Gerrard, Juliet A.;
Grant Pearce, Frederick

Publication type:

Article

Caspase Inhibitors of the P35 Family Are More Active When Purified from Yeast than Bacteria.

Published in:

PLoS ONE, 2012, v. 7, n. 6, p. 1, doi. 10.1371/journal.pone.0039248

By:

Brand, Ingo L.;
Civciristov, Srgjan;
Taylor, Nicole L.;
Talbo, Gert H.;
Pantaki-Eimany, Delara;
Levina, Vita;
Clem, Rollie J.;
Perugini, Matthew A.;
Kvansakul, Marc;
Hawkins, Christine J.

Publication type:

Article

Crystal, Solution and In silico Structural Studies of Dihydrodipicolinate Synthase from the Common Grapevine.

Published in:

PLoS ONE, 2012, v. 7, n. 6, p. 1, doi. 10.1371/journal.pone.0038318

By:

Atkinson, Sarah C.;
Dogovski, Con;
Downton, Matthew T.;
Pearce, F. Grant;
Reboul, Cyril F.;
Buckle, Ashley M.;
Gerrard, Juliet A.;
Dobson, Renwick C. J.;
Wagner, John;
Perugini, Matthew A.

Publication type:

Article

Age-Related Differences in Plasma Proteins: How Plasma Proteins Change from Neonates to Adults.

Published in:

PLoS ONE, 2011, v. 6, n. 2, p. 1, doi. 10.1371/journal.pone.0017213

By:

Ignjatovic, Vera;
Lai, Cera;
Summerhayes, Robyn;
Mathesius, Ulrike;
Tawfilis, Sherif;
Perugini, Matthew A.;
Paul Monagle

Publication type:

Article

Characterization of recombinant dihydrodipicolinate synthase from the bread wheat Triticum aestivum.

Published in:

Planta: An International Journal of Plant Biology, 2018, v. 248, n. 2, p. 381, doi. 10.1007/s00425-018-2894-x

By:

Gupta, Ruchi;
Hogan, Campbell J.;
Perugini, Matthew A.;
Soares da Costa, Tatiana P.

Publication type:

Article

The structural basis for autonomous dimerization of the pre-T-cell antigen receptor.

Published in:

Nature, 2010, v. 467, n. 7317, p. 844, doi. 10.1038/nature09448

By:

Siew Siew Pang;
Berry, Richard;
Zhenjun Chen;
Lars Kjer-Nielsen;
Matthew A. Perugini;
King, Glenn F.;
Christina Wang;
Sock Hui Chew;
La Gruta, Nicole L.;
Williams, Neal K.;
Beddoe, Travis;
Tiganis, Tony;
Cowieson, Nathan P.;
Godfrey, Dale I.;
Purcell, Anthony W.;
Wilce, Matthew C. J.;
McCluskey, James;
Rossjohn, Jamie

Publication type:

Article

Membrane Core-Specific Antimicrobial Action of Cathelicidin LL-37 Peptide Switches Between Pore and Nanofibre Formation.

Published in:

Scientific Reports, 2016, p. 38184, doi. 10.1038/srep38184

By:

Shahmiri, Mahdi;
Enciso, Marta;
Adda, Christopher G.;
Smith, Brian J.;
Perugini, Matthew A.;
Mechler, Adam

Publication type:

Article

Structure and Function of Cyanobacterial DHDPS and DHDPR.

Published in:

Scientific Reports, 2016, p. 37111, doi. 10.1038/srep37111

By:

Christensen, Janni B.;
Soares da Costa, T. P.;
Faou, Pierre;
Pearce, F. Grant;
Panjikar, Santosh;
Perugini, Matthew A.

Publication type:

Article

Insight into the self-association of key enzymes from pathogenic species.

Published in:

European Biophysics Journal, 2005, v. 34, n. 5, p. 469, doi. 10.1007/s00249-005-0491-y

By:

Perugini, Matthew A.;
Griffin, Michael D. W.;
Smith, Brian J.;
Webb, Lauren E.;
Davis, Antony J.;
Handman, Emanuela;
Gerrard, Juliet A.

Publication type:

Article

Structural, kinetic and computational investigation of Vitis vinifera DHDPS reveals new insight into the mechanism of lysine-mediated allosteric inhibition.

Published in:

Plant Molecular Biology, 2013, v. 81, n. 4-5, p. 431, doi. 10.1007/s11103-013-0014-7

By:

Atkinson, Sarah;
Dogovski, Con;
Downton, Matthew;
Czabotar, Peter;
Dobson, Renwick;
Gerrard, Juliet;
Wagner, John;
Perugini, Matthew

Publication type:

Article

Differential lysine‐mediated allosteric regulation of plant dihydrodipicolinate synthase isoforms.

Published in:

FEBS Journal, 2021, v. 288, n. 16, p. 4973, doi. 10.1111/febs.15766

By:

Hall, Cody J.;
Lee, Mihwa;
Boarder, Matthew P.;
Mangion, Alexandra M.;
Gendall, Anthony R.;
Panjikar, Santosh;
Perugini, Matthew A.;
Soares da Costa, Tatiana P.

Publication type:

Article

Identification of two dihydrodipicolinate synthase isoforms from Pseudomonas aeruginosa that differ in allosteric regulation.

Published in:

FEBS Journal, 2020, v. 287, n. 2, p. 386, doi. 10.1111/febs.15014

By:

Impey, Rachael E.;
Panjikar, Santosh;
Hall, Cody J.;
Bock, Lucy J.;
Sutton, J. Mark;
Perugini, Matthew A.;
Soares da Costa, Tatiana P.

Publication type:

Article

Works by Matthew A. Perugini

Polymerase delta-interacting protein 38 (PDIP38) modulates the stability and activity of the mitochondrial AAA+ protease CLPXP.

The oligomeric assembly of galectin-11 is critical for anti-parasitic activity in sheep (Ovis aries).

A partially structured region of a largely unstructured protein, Plasmodium falciparum merozoite surface protein 2 (MSP2), forms amyloid-like fibrils.

Mis‐annotations of a promising antibiotic target in high‐priority gram‐negative pathogens.

An intact membrane is essential for small extracellular vesicle‐induced modulation of α‐synuclein fibrillization.

Towards novel herbicide modes of action by inhibiting lysine biosynthesis in plants.

Structural insights into BCL2 pro-survival protein interactions with the key autophagy regulator BECN1 following phosphorylation by STK4/MST1.

Crystal structure of the Leishmania major MIX protein: A scaffold protein that mediates protein-protein interactions.

Conserved main-chain peptide distortions: A proposed role for Ile203 in catalysis by dihydrodipicolinate synthase.

Size matters! Fragmentation chemistry of [Cu(L)<sub>n</sub>]<sup>2+</sup> complexes of diacylglycerophosphocholines as a function of coordination number (n = 2-7).

Identification of a dimeric KDG aldolase from Agrobacterium tumefaciens.

Identification of the bona fide DHDPS from a common plant pathogen.

A Family of Helminth Molecules that Modulate Innate Cell Responses via Molecular Mimicry of Host Antimicrobial Peptides.

Targeting of a natural killer cell receptor family by a viral immunoevasin.

Integrated activities of two alternative sigma factors coordinate iron acquisition and uptake by Pseudomonas aeruginosa.

Dual roles of F123 in protein homodimerization and inhibitor binding to biotin protein ligase from Staphylococcus aureus.

The BECN1 N-terminal domain is intrinsically disordered.

Dynamic Modelling Reveals ‘Hotspots’ on the Pathway to Enzyme-Substrate Complex Formation.

Shark Variable New Antigen Receptor (V<sub>NAR</sub>) Single Domain Antibody Fragments: Stability and Diagnostic Applications.

Defining the interaction of perforin with calcium and the phospholipid membrane.

Review: amino acid biosynthesis as a target for herbicide development.

Homodimerization attenuates the anti-inflammatory activity of interleukin-37.

New method for purifying histidine-rich glycoprotein from human plasma redefines its functional properties.

From Knock-Out Phenotype to Three-Dimensional Structure of a Promising Antibiotic Target from <i>Streptococcus pneumoniae</i>.

High-Throughput Screening for Novel Inhibitors of Neisseria gonorrhoeae Penicillin-Binding Protein 2.

Ultramarine, a Chromoprotein Acceptor for Förster Resonance Energy Transfer.

Characterisation of the First Enzymes Committed to Lysine Biosynthesis in Arabidopsis thaliana.

Caspase Inhibitors of the P35 Family Are More Active When Purified from Yeast than Bacteria.

Crystal, Solution and In silico Structural Studies of Dihydrodipicolinate Synthase from the Common Grapevine.

Age-Related Differences in Plasma Proteins: How Plasma Proteins Change from Neonates to Adults.

Characterization of recombinant dihydrodipicolinate synthase from the bread wheat Triticum aestivum.

The structural basis for autonomous dimerization of the pre-T-cell antigen receptor.

Membrane Core-Specific Antimicrobial Action of Cathelicidin LL-37 Peptide Switches Between Pore and Nanofibre Formation.

Structure and Function of Cyanobacterial DHDPS and DHDPR.

Insight into the self-association of key enzymes from pathogenic species.

Structural, kinetic and computational investigation of Vitis vinifera DHDPS reveals new insight into the mechanism of lysine-mediated allosteric inhibition.

Differential lysine‐mediated allosteric regulation of plant dihydrodipicolinate synthase isoforms.

Identification of two dihydrodipicolinate synthase isoforms from Pseudomonas aeruginosa that differ in allosteric regulation.