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Repair of diverse diabetic defects of β-cells in man and mouse by pharmacological glucokinase activation.
- Published in:
- Diabetes, Obesity & Metabolism, 2012, v. 14, p. 109, doi. 10.1111/j.1463-1326.2012.01652.x
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- Article
Structural and functional abnormalities in the islets isolated from type 2 diabetic subjects.
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- 2004
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- Publication type:
- journal article
Permanent Neonatal Diabetes Caused by Glucokinase Deficiency.
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- Diabetes, 2003, v. 52, n. 11, p. 2854, doi. 10.2337/diabetes.52.11.2854
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- Article
Rapamycin Has a Deleterious Effect on MIN-6 Cells and Rat and Human Islets.
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- Diabetes, 2003, v. 52, n. 11, p. 2730, doi. 10.2337/diabetes.52.11.2731
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- Article
Insights into the biochemical and genetic basis of glucokinase activation from naturally occurring hypoglycemia mutations.
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- 2003
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- Publication type:
- journal article
Differential effects of glucose and glyburide on energetics and Na+ levels of betaHC9 cells: nuclear magnetic resonance spectroscopy and respirometry studies.
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- 2003
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- journal article
Regulation of pancreatic beta-cell glucokinase: from basics to therapeutics.
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- 2002
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- journal article
Glutaminolysis and insulin secretion: from bedside to bench and back.
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- 2002
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- journal article
Regulation of Pancreatic Β-Cell Glucokinase.
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- Diabetes, 2002, v. 51, p. S394, doi. 10.2337/diabetes.51.2007.S394
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- Article
Foxa2 controls Pdx1 gene expression in pancreatic beta-cells in vivo.
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- 2002
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- journal article
Foxa2 Controls Pdx1 Gene Expression ni Pancreatic β-Cells In Vivo.
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- Diabetes, 2002, v. 51, n. 8, p. 2546, doi. 10.2337/diabetes.51.8.2546
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- Publication type:
- Article
The second activating glucokinase mutation (A456V): implications for glucose homeostasis and diabetes therapy.
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- 2002
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- Publication type:
- journal article
Structural model of human glucokinase in complex with glucose and ATP: implications for the mutants that cause hypo- and hyperglycemia.
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- 1999
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- Publication type:
- journal article
Glucose Regulation of Glutaminolysis and Its Role in Insulin Secretion.
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- Diabetes, 1999, v. 48, n. 8, p. 1535, doi. 10.2337/diabetes.48.8.1535
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- Article
Pancreatic beta-cell glucokinase.
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- Diabetes, 1998, v. 47, n. 3, p. 307, doi. 10.2337/diabetes.47.3.307
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- Publication type:
- Article
Wortmannin Inhibits Insulin Secretion in Pancreatic Islets and β-TC3 Cells Independent of Its Inhibition of Phosphatidylinositol 3-Kinase.
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- Diabetes, 1996, v. 45, n. 7, p. 854, doi. 10.2337/diab.45.7.854
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- Publication type:
- Article
A Lesson in Metabolic Regulation Inspired by the Glucokinase Glucose Sensor Paradigm.
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- Diabetes, 1996, v. 45, n. 2, p. 223, doi. 10.2337/diab.45.2.223
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- Publication type:
- Article
Effects of Glucose on Insulin Secretion, Glucokinase Activity, and Transgene Expression in Transgenic Mouse Islets Containing an Upstream Glucokinase Promoter-Human Growth Hormone Fusion Gene.
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- Diabetes, 1994, v. 43, n. 9, p. 1138, doi. 10.2337/diab.43.9.1138
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- Article
Sulfonylurea-binding sites and ATP-sensitive K+ channels in alpha-TC glucagonoma and beta-TC insulinoma cells.
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- 1993
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- Publication type:
- journal article
Concordant Glucose Induction of Glucokinase, Glucose Usage, and Glucose-Stimulated Insulin Release in Pancreatic Islets Maintained in Organ Culture.
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- Diabetes, 1992, v. 41, n. 7, p. 792, doi. 10.2337/diab.41.7.792
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- Article
Effect of linogliride on hormone release from perfused rat pancreas. Fuel dependence and desensitization by tolbutamide.
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- 1991
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- journal article
Content of CoA-Esters in Perifused Rat Islets Stimulated by Glucose and Other Fuels.
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- Diabetes, 1991, v. 40, n. 3, p. 327
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- Publication type:
- Article
Diabetes and the myo-inositol paradox.
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- 1990
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- journal article
Glucokinase as glucose sensor and metabolic signal generator in pancreatic beta-cells and hepatocytes.
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- 1990
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- Publication type:
- journal article
Functional Pancreatic β-Cell Line From SV40 T-Antigen Transgenic Mouse.
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- Diabetes, 1989, v. 38, n. 8, p. 1056, doi. 10.2337/diab.38.8.1056
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- Article
Control of Glucose Metabolism in Pancreatic β-Cells by Glucokinase, Hexokinase, and Phosphofructokinase.
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- Diabetes, 1988, v. 37, n. 11, p. 1524, doi. 10.2337/diab.37.11.1524
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- Article
Control of glucose phosphorylation and glucose usage in clonal insulinoma cells.
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- 1988
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- journal article
Fuel-stimulated insulin secretion by clonal hamster beta-cell line HIT T-15.
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- 1987
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- Publication type:
- journal article
Regulatory role of fructose-2,6-bisphosphate in pancreatic islet glucose metabolism remains unsettled.
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- 1985
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- journal article
Fuel-induced insulin release in vitro from insulinomas transplanted into the rat kidney.
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- 1984
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- Publication type:
- journal article
Mannose phosphorylation by glucokinase from liver and transplantable insulinoma. Cooperativity and discrimination of anomers.
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- 1983
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- Publication type:
- journal article
β-arrestin-2 is an essential regulator of pancreatic β-cell function under physiological and pathophysiological conditions.
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- Nature Communications, 2017, v. 8, n. 2, p. 14295, doi. 10.1038/ncomms14295
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- Article
Functional and Metabolomic Consequences of K<sub>ATP</sub> Channel Inactivation in Human Islets.
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- 2017
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- journal article
Susceptibility of glucokinase-MODY mutants to inactivation by oxidative stress in pancreatic β-cells.
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- 2011
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- Publication type:
- journal article
Susceptibility of Glucokinase-MODY Mutants to Inactivation by Oxidative Stress in Pancreatic β-Cells.
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- Diabetes, 2011, v. 60, n. 12, p. 3175, doi. 10.2337/db11-0423
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- Publication type:
- Article
Extremes of Clinical and Enzymatic Phenotypes in Children With Hyperinsulinism Caused by Glucokinase Activating Mutations.
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- Diabetes, 2009, v. 58, n. 6, p. 1419, doi. 10.2337/db08-1792
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- Publication type:
- Article
Cell Biology Assessment of Glucokinase Mutations V62M and G72R in Pancreatic β-Cells.
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- Diabetes, 2007, v. 56, n. 7, p. 1773, doi. 10.2337/db06-1151
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- Article
Acute Inhibition of Islet Respiration and Acetylcholine Responsiveness by Fatty Acids.
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- Diabetes, 2007, v. 56, p. A440
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- Publication type:
- Article
Chronic Elevation of IntraceHular Calcium Impairs the GABA Shunt in Pancreatic Islets of SUR1 Knockout Mice -- Studies with U-13C-Glucose.
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- Diabetes, 2007, v. 56, p. A439
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- Publication type:
- Article
The Role of Glutamine-Glutamate-a-Ketoglutarate Axis in Amino Acid Stimulated Insulin Secretion in the beta-HC9 Cells.
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- Diabetes, 2007, v. 56, p. A435
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- Publication type:
- Article
Foxa1-Deficient Mice Exhibit Impaired Insulin Secretion due to Uncoupled Oxidative Phosphorylation.
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- Diabetes, 2006, v. 55, n. 10, p. 2730, doi. 10.2337/db05-0470
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- Publication type:
- Article
Nitrosative stress, uric acid, and peripheral nerve function in early type 1 diabetes. Diabetes 51:2817-2825.
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- 2006
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- Publication type:
- corrected article
A Glucose Sensor Role for Glucokinase in Anterior Pituitary Cells.
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- 2006
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- Publication type:
- Abstract
From Clinicogenetic Studies of Maturity-Onset Diabetes of the Young to Unraveling Complex Mechanisms of Glucokinase Regulation.
- Published in:
- Diabetes, 2006, v. 55, n. 6, p. 1713, doi. 10.2337/db05-1513
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- Publication type:
- Article
The Network of Glucokinase-Expressing Cells in Glucose Homeostasis and the Potential of Glucokinase Activators for Diabetes Therapy.
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- Diabetes, 2006, v. 55, n. 1, p. 1, doi. 10.2337/diabetes.55.01.06.db05-0926
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- Publication type:
- Article
Integration of Eukaryotic Energy Metabolism: The Intramitochondrial and Cytosolic Energy States ([ATP] f /[ADP] f [Pi]).
- Published in:
- International Journal of Molecular Sciences, 2022, v. 23, n. 10, p. 5550, doi. 10.3390/ijms23105550
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- Publication type:
- Article
Cytotoxic Effect of β-Amyloid on a Human Differentiated Neuron Is Not Mediated by Cytoplasmic Ca<sup>2+</sup> Accumulation.
- Published in:
- Journal of Neurochemistry, 1998, v. 70, n. 4, p. 1394, doi. 10.1046/j.1471-4159.1998.70041394.x
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- Publication type:
- Article
A phospho-BAD BH3 helix activates glucokinase by a mechanism distinct from that of allosteric activators.
- Published in:
- Nature Structural & Molecular Biology, 2014, v. 21, n. 1, p. 36, doi. 10.1038/nsmb.2717
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- Publication type:
- Article
Analysis of the co-operative interaction between the allosterically regulated proteins GK and GKRP using tryptophan fluorescence.
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- Biochemical Journal, 2014, v. 459, n. 3, p. 551, doi. 10.1042/BJ20131363
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- Publication type:
- Article
Distribution of myo-Inositol in the Cat Cochlear Nucleus.
- Published in:
- Journal of Neurochemistry, 1982, v. 38, n. 4, p. 939, doi. 10.1111/j.1471-4159.1982.tb05333.x
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- Publication type:
- Article