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Evaluatie van een nieuwe Nederlandse vancomycinedoseerrichtlijn en populatiefarmaco kinetiek van vancomycine bij preterme en a terme neonaten.
Published in:
Nederlands Platform voor Farmaceutisch Onderzoek, 2019, v. 4, p. 1
By:
- Koedood, L.;
- de Haan, T. R.;
- Hodiamont, C. J.;
- van Haelst, I. M. M.;
- Mathôt, R. A. A.
Publication type:
Article
The role of plasma concentrations and drug characteristics of beta‐blockers in fall risk of older persons.
Published in:
Pharmacology Research & Perspectives, 2023, v. 11, n. 6, p. 1, doi. 10.1002/prp2.1126
By:
- Ploegmakers, K. J.;
- van Poelgeest, E. P.;
- Seppala, L. J.;
- van Dijk, S. C.;
- de Groot, L. C. P. G. M.;
- Oliai Araghi, S.;
- van Schoor, N. M.;
- Stricker, B.;
- Swart, K. M. A.;
- Uitterlinden, A. G.;
- Mathôt, R. A. A.;
- van der Velde, N.
Publication type:
Article
In silico evaluation of limited sampling strategies for individualized dosing of extended half-life factor IX concentrates in hemophilia B patients.
Published in:
European Journal of Clinical Pharmacology, 2022, v. 78, n. 2, p. 237, doi. 10.1007/s00228-021-03173-2
By:
- Preijers, T.;
- van Spengler, M. W. F.;
- Meijer, K.;
- Fijnvandraat, K.;
- Fischer, K.;
- Leebeek, F. W. G.;
- Cnossen, M. H.;
- Mathôt, R. A. A.
Publication type:
Article
Population Pharmacokinetics and Pharmacodynamics of Ciprofloxacin Prophylaxis in Pediatric Acute Lymphoblastic Leukemia Patients.
Published in:
Clinical Infectious Diseases, 2020, v. 71, n. 8, p. e281, doi. 10.1093/cid/ciz1163
By:
- Sassen, S D T;
- Mathôt, R A A;
- Pieters, R;
- Haas, V de;
- Kaspers, G J L;
- Bos, C van den;
- Tissing, W J E;
- Loo, D M W W te;
- Bierings, M B;
- Westreenen, M van;
- Sluis, I M van der;
- Zwaan, C M
Publication type:
Article
Population Pharmacokinetics of Amoxicillin in Term Neonates Undergoing Moderate Hypothermia.
Published in:
Clinical Pharmacology & Therapeutics, 2018, v. 103, n. 3, p. 458, doi. 10.1002/cpt.748
By:
- Bijleveld, Y. A.;
- Mathôt, R. A. A.;
- Van Der Lee, J. H.;
- Groenendaal, F.;
- Dijk, P. H.;
- Van Heijst, A.;
- Simons, S. H. P.;
- Dijkman, K. P.;
- Van Straaten, H. L. M.;
- Rijken, M.;
- Zonnenberg, I. A.;
- Cools, F.;
- Zecic, A.;
- Nuytemans, D. H. G. M.;
- Van Kaam, A. H.;
- De Haan, T. R.;
- For The Pharmacool Study Group
Publication type:
Article
Population pharmacokinetics and exploratory pharmacodynamics of ifosfamide and metabolites after a 72-h continuous infusion in patients with soft tissue sarcoma.
Published in:
European Journal of Clinical Pharmacology, 2001, v. 57, n. 6/7, p. 467, doi. 10.1007/s002280100322
By:
- Kerbusch, T.;
- Mathôt, R.;
- Keizer, H.;
- Ouwerkerk, J.;
- Rodenhuis, S.;
- Schellens, J.;
- Beijnen, J.
Publication type:
Article
A population analysis of the pharmacokinetics of Cremophor EL using nonlinear mixed-effect modelling.
Published in:
Cancer Chemotherapy & Pharmacology, 2002, v. 50, n. 1, p. 16, doi. 10.1007/s00280-002-0459-x
By:
- van den Bongard, H. J. G. D.;
- Mathôt, R. A. A.;
- van Tellingen, O.;
- Schellens, J. H. M.;
- Beijnen, J. H.
Publication type:
Article
Application of SHAP values for inferring the optimal functional form of covariates in pharmacokinetic modeling.
Published in:
CPT: Pharmacometrics & Systems Pharmacology, 2022, v. 11, n. 8, p. 1100, doi. 10.1002/psp4.12828
By:
- Janssen, Alexander;
- Hoogendoorn, Mark;
- Cnossen, Marjon H.;
- Mathôt, Ron A. A.;
- Cnossen, M. H.;
- Reitsma, S. H.;
- Leebeek, F. W. G.;
- Mathôt, R. A. A.;
- Fijnvandraat, K.;
- Coppens, M.;
- Meijer, K.;
- Schols, S. E. M.;
- Eikenboom, H. C. J.;
- Schutgens, R. E. G.;
- Beckers, E. A. M.;
- Ypma, P.;
- Kruip, M. J. H. A.;
- Polinder, S.;
- Tamminga, R. Y. J.;
- Brons, P.
Publication type:
Article
Development and validation of limited sampling strategies for prediction of the systemic exposure to the novel anticancer agent E7070 (N-(3-chloro-7-indolyl)-1,4-benzenedisulphonamide).
Published in:
British Journal of Clinical Pharmacology, 2002, v. 54, n. 5, p. 463, doi. 10.1046/j.1365-2125.2002.01684.x
By:
- van Kesteren, Charlotte;
- Mathôt, R. A. A.;
- Raymond, E.;
- Armand, J. P.;
- Fumoleau, P.;
- Punt, C.;
- Ravic, M.;
- Wanders, J.;
- Beijnen, J. H.;
- Schellens, J. H. M.
Publication type:
Article
Population pharmacokinetics and pharmacokinetic-pharmacodynamic relationships of the novel anticancer agent E7070 in four phase I studies.
Published in:
2002
By:
- van Kesteren, CH;
- Mathôt, R. A. A;
- Raymond, E;
- Armand, J. P;
- Dittrich, CH;
- Dumez, H;
- Roché, H;
- Droz, J. P;
- Punt, C;
- Ravic, M;
- Wanders, J;
- Beijnen, J. H;
- Fumoleau, P;
- Schellens, J. H. M
Publication type:
Abstract
A population pharmacokinetic model for Cremophor EL using nonlinear mixed-effect modeling: model building and validation.
Published in:
2002
By:
- van den Bongard, H. J. G. D;
- Mathôt, R. A. A;
- van Tellingen, O;
- Schellens, J. H. M;
- Beijnen, J. H
Publication type:
Abstract
The effect of fluconazole on ritonavir and saquinavir pharmacokinetics in HIV-1-infected individuals.
Published in:
British Journal of Clinical Pharmacology, 2001, v. 51, n. 6, p. 631, doi. 10.1046/j.0306-5251.2001.01409.x
By:
- Koks, C. H. W.;
- Crommentuyn, K. M. L.;
- Hoetelmans, R. M. W.;
- Burger, D. M.;
- Koopmans, P. P.;
- Mathôt, R. A. A.;
- Mulder, J. W.;
- Meenhorst, P. L.;
- Beijnen, J. H.
Publication type:
Article
Pharmacokinetically guided administration of chemotherapeutic agents.
Published in:
2000
By:
- van den Bongard, H.J.G.D.;
- Mathôt, R.A.A.;
- Beijnen, J.H.;
- Schellens, J.H.M.;
- van den Bongard, H J;
- Mathôt, R A;
- Schellens, J H
Publication type:
journal article
Pharmacodynamics and kinetics of omeprazole MUPS 20 mg and pantoprazole 40 mg during repeated oral administration in Helicobacter pylori-negative subjects.
Published in:
Alimentary Pharmacology & Therapeutics, 2000, v. 14, n. 8, p. 1057, doi. 10.1046/j.1365-2036.2000.00806.x
By:
- Geus, W. P.;
- Mathôt, R. A. A.;
- Mulder, P. G. H.;
- Lamers, C. B. H. W.
Publication type:
Article
The relative importance of cyclosporine exposure in heart, kidney or liver transplant recipients on maintenance therapy.
Published in:
Transplant International, 2004, v. 17, n. 9, p. 495, doi. 10.1111/j.1432-2277.2004.tb00478.x
By:
- D. A. Hesselink;
- T. van Dam;
- H. J. Metselaar;
- A. H. M. M. Balk;
- R. A. A. Mathôt;
- P. J. H. Smak Gregoor;
- W. Weimar;
- T. van Gelder
Publication type:
Article
Perioperative replacement therapy in haemophilia B: An appeal to “B” more precise.
Published in:
Haemophilia, 2018, v. 24, n. 4, p. 611, doi. 10.1111/hae.13469
By:
- Hazendonk, H. C. A. M.;
- Preijers, T.;
- Liesner, R.;
- Chowdary, P.;
- Hart, D.;
- Keeling, D.;
- Driessens, M. H. E.;
- Laros‐van Gorkom, B. A. P.;
- van der Meer, F. J. M.;
- Meijer, K.;
- Fijnvandraat, K.;
- Leebeek, F. W. G.;
- Mathôt, R. A. A.;
- Collins, P. W.;
- Cnossen, M. H.
Publication type:
Article
Analysis of current perioperative management with Haemate<sup>®</sup> P/Humate P<sup>®</sup> in von Willebrand disease: Identifying the need for personalized treatment.
Published in:
Haemophilia, 2018, v. 24, n. 3, p. 460, doi. 10.1111/hae.13451
By:
- the “OPTI‐CLOT" and “WIN" study group;
- Hazendonk, H. C. A. M.;
- Heijdra, J. M.;
- Veerman, H. C.;
- van Moort, I.;
- Cnossen, M. H.;
- de Jager, N. C. B.;
- Mathôt, R. A. A.;
- Boender, J.;
- Leebeek, F. W. G.;
- Meijer, K.;
- Laros‐van Gorkom, B. A. P.;
- Eikenboom, J.;
- Fijnvandraat, K.
Publication type:
Article
Effect of intravenous paracetamol on postoperative morphine requirements in neonates and infants undergoing major noncardiac surgery: a randomized controlled trial.
Published in:
2013
By:
- Ceelie I;
- de Wildt SN;
- van Dijk M;
- van den Berg MM;
- van den Bosch GE;
- Duivenvoorden HJ;
- de Leeuw TG;
- Mathôt R;
- Knibbe CA;
- Tibboel D;
- Ceelie, Ilse;
- de Wildt, Saskia N;
- van Dijk, Monique;
- van den Berg, Margreeth M J;
- van den Bosch, Gerbrich E;
- Duivenvoorden, Hugo J;
- de Leeuw, Tom G;
- Mathôt, Ron;
- Knibbe, Catherijne A J;
- Tibboel, Dick
Publication type:
journal article
Impact of mucositis on oral bioavailability and systemic exposure of ciprofloxacin Gram-negative infection prophylaxis in patients with haematological malignancies.
Published in:
Journal of Antimicrobial Chemotherapy (JAC), 2022, v. 77, n. 11, p. 3069, doi. 10.1093/jac/dkac283
By:
- Rhee, K P van;
- Vroom, S L de;
- Hest, R M van;
- Linden, P D van der;
- Tonino, S H;
- Molendijk, E;
- Mathôt, R A A;
- Blijlevens, N M A;
- Knibbe, C A J;
- Bruggemann, R J M;
- Geerlings, S E;
- van Rhee, K P;
- de Vroom, S L;
- van Hest, R M;
- van der Linden, P D
Publication type:
Article
Impact of a vancomycin loading dose on the achievement of target vancomycin exposure in the first 24 h and on the accompanying risk of nephrotoxicity in critically ill patients.
Published in:
2021
By:
- Hodiamont, C J;
- Juffermans, N P;
- Berends, S E;
- Vessem, D J van;
- Hakkens, N;
- Mathôt, R A A;
- Jong, M D de;
- Hest, R M van;
- van Vessem, D J;
- de Jong, M D;
- van Hest, R M
Publication type:
journal article
Evaluatie van een nieuwe Nederlandse vancomycinedoseerrichtlijn en populatiefarmacokinetiek van vancomycine bij preterme en a terme neonaten.
Published in:
Nederlands Platform voor Farmaceutisch Onderzoek, 2019, v. 4, p. 1
By:
- Koedood, L.;
- de Haan, T. R.;
- Hodiamont, C. J.;
- van Haelst, I. M. M.;
- Mathôt, R. A. A.
Publication type:
Article
Evaluatie van doseerrichtlijnen en populatiefarmacokinetiek van vancomycine bij kinderen met kanker.
Published in:
Nederlands Platform voor Farmaceutisch Onderzoek, 2017, v. 2, p. 1
By:
- van Egmond, P. S.;
- van Eijkelenburg, N. K. A.;
- Zwaan, C. M.;
- Mathôt, R. A. A.
Publication type:
Article

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