Works matching AU Massarotti, Alberto

Results: 18

The SNAP-tag technology revised: an effective chemo-enzymatic approach by using a universal azide-based substrate.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2021, v. 36, n. 1, p. 85, doi. 10.1080/14756366.2020.1841182

By:

Merlo, Rosa;
Caprioglio, Diego;
Cillo, Michele;
Valenti, Anna;
Mattossovich, Rosanna;
Morrone, Castrese;
Massarotti, Alberto;
Rossi, Franca;
Miggiano, Riccardo;
Leonardi, Antonio;
Minassi, Alberto;
Perugino, Giuseppe

Publication type:

Article

Structure activity relationship studies on Amb639752: toward the identification of a common pharmacophoric structure for DGKα inhibitors.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2020, v. 35, n. 1, p. 96, doi. 10.1080/14756366.2019.1684911

By:

Velnati, Suresh;
Massarotti, Alberto;
Antona, Annamaria;
Talmon, Maria;
Fresu, Luigia Grazia;
Galetto, Alessandra Silvia;
Capello, Daniela;
Bertoni, Alessandra;
Mercalli, Valentina;
Graziani, Andrea;
Tron, Gian Cesare;
Baldanzi, Gianluca

Publication type:

Article

The adverse outcome pathway ( AOP) for chemical binding to tubulin in oocytes leading to aneuploid offspring.

Published in:

Environmental & Molecular Mutagenesis, 2016, v. 57, n. 2, p. 87, doi. 10.1002/em.21986

By:

Marchetti, Francesco;
Massarotti, Alberto;
Yauk, Carole L.;
Pacchierotti, Francesca;
Russo, Antonella

Publication type:

Article

Psychotropic Drugs Show Anticancer Activity by Disrupting Mitochondrial and Lysosomal Function.

Published in:

Frontiers in Oncology, 2020, v. 11, p. N.PAG, doi. 10.3389/fonc.2020.562196

By:

Varalda, Marco;
Antona, Annamaria;
Bettio, Valentina;
Roy, Konkonika;
Vachamaram, Ajay;
Yellenki, Vaibhav;
Massarotti, Alberto;
Baldanzi, Gianluca;
Capello, Daniela

Publication type:

Article

Zinc ions modulate protein tyrosine phosphatase 1B activity.

Published in:

Metallomics, 2014, v. 6, n. 7, p. 1229, doi. 10.1039/c4mt00086b

By:

Bellomo, Elisa;
Massarotti, Alberto;
Hogstrand, Christer;
Maret, Wolfgang

Publication type:

Article

Identification of a Potent Phosphoinositide 3-Kinase Pan Inhibitor Displaying a Strategic Carboxylic Acid Group and Development of Its Prodrugs.

Published in:

ChemMedChem, 2017, v. 12, n. 18, p. 1542, doi. 10.1002/cmdc.201700340

By:

Pirali, Tracey;
Ciraolo, Elisa;
Aprile, Silvio;
Massarotti, Alberto;
Berndt, Alex;
Griglio, Alessia;
Serafini, Marta;
Mercalli, Valentina;
Landoni, Clarissa;
Campa, Carlo Cosimo;
Margaria, Jean Piero;
Silva, Rangel L.;
Grosa, Giorgio;
Sorba, Giovanni;
Williams, Roger;
Hirsch, Emilio;
Tron, Gian Cesare

Publication type:

Article

Are 1,4- and 1,5-Disubstituted 1,2,3-Triazoles Good Pharmacophoric Groups?

Published in:

ChemMedChem, 2014, v. 9, n. 11, p. 2497, doi. 10.1002/cmdc.201402233

By:

Massarotti, Alberto;
Aprile, Silvio;
Mercalli, Valentina;
Del Grosso, Erika;
Grosa, Giorgio;
Sorba, Giovanni;
Tron, Gian Cesare

Publication type:

Article

A Concise Synthesis of Pyrazole Analogues of Combretastatin A1 as Potent Anti-Tubulin Agents.

Published in:

ChemMedChem, 2013, v. 8, n. 4, p. 633, doi. 10.1002/cmdc.201200561

By:

Zaninetti, Roberta;
Cortese, Salvatore V.;
Aprile, Silvio;
Massarotti, Alberto;
Canonico, Pier Luigi;
Sorba, Giovanni;
Grosa, Giorgio;
Genazzani, Armando A.;
Pirali, Tracey

Publication type:

Article

The Tubulin Colchicine Domain: a Molecular Modeling Perspective.

Published in:

ChemMedChem, 2012, v. 7, n. 1, p. 33, doi. 10.1002/cmdc.201100361

By:

Massarotti, Alberto;
Coluccia, Antonio;
Silvestri, Romano;
Sorba, Giovanni;
Brancale, Andrea

Publication type:

Article

Estrogenic Analogues Synthesized by Click Chemistry.

Published in:

ChemMedChem, 2007, v. 2, n. 4, p. 437, doi. 10.1002/cmdc.200600192

By:

Pirali, Tracey;
Gatti, Silvia;
Di Brisco, Roberto;
Tacchi, Sara;
Zaninetti, Roberta;
Brunelli, Elisa;
Massarotti, Alberto;
Sorba, Giovanni;
Canonico, Pier Luigi;
Moro, Laura;
Genazzani, Armando A.;
Tron, Gian Cesare;
Billington, Richard A.

Publication type:

Article

2‐(Methyl(phenyl)amino)‐N‐(phenyloxyphenyl)acetamide structural motif representing a framework for selective SIRT2 inhibition.

Published in:

Drug Development Research, 2024, v. 85, n. 4, p. 1, doi. 10.1002/ddr.22224

By:

Kaya, Selen Gozde;
Eren, Gokcen;
Massarotti, Alberto;
Bakar‐Ates, Filiz;
Ozkan, Erva;
Gozelle, Mahmut;
Ozkan, Yesim

Publication type:

Article

Crystal structure of human nicotinic acid phosphoribosyltransferase.

Published in:

FEBS Open Bio, 2015, v. 5, p. 419, doi. 10.1016/j.fob.2015.05.002

By:

Marletta, Ada Serena;
Massarotti, Alberto;
Orsomando, Giuseppe;
Magni, Giulio;
Rizzi, Menico;
Garavaglia, Silvia

Publication type:

Article

Symmetrical 2,7‐disubstituted 9H‐fluoren‐9‐one as a novel and promising scaffold for selective targeting of SIRT2.

Published in:

Archiv der Pharmazie, 2024, v. 357, n. 12, p. 1, doi. 10.1002/ardp.202400661

By:

Kaya, Selen Gozde;
Eren, Gokcen;
Massarotti, Alberto;
Gunindi, Habibe Beyza;
Bakar‐Ates, Filiz;
Ozkan, Erva

Publication type:

Article

The Guareschi Pyridine Scaffold as a Valuable Platform for the Identification of Selective PI3K Inhibitors.

Published in:

Molecules, 2015, v. 20, n. 9, p. 17275, doi. 10.3390/molecules200917275

By:

Galli, Ubaldina;
Ciraolo, Elisa;
Massarotti, Alberto;
Margaria, Jean Piero;
Sorba, Giovanni;
Hirsch, Emilio;
Tron, Gian Cesare

Publication type:

Article

In silico approach reveals N-(5-phenoxythiophen-2-yl)-2-(arylthio)acetamides as promising selective SIRT2 inhibitors: the case of structural optimization of virtual screening-derived hits.

Published in:

Journal of Biomolecular Structure & Dynamics, 2025, v. 43, n. 4, p. 1756, doi. 10.1080/07391102.2023.2293252

By:

Gozelle, Mahmut;
Bakar-Ates, Filiz;
Massarotti, Alberto;
Ozkan, Erva;
Gunindi, Habibe Beyza;
Ozkan, Yesim;
Eren, Gokcen

Publication type:

Article

The [1,2,4]Triazolo[4,3‐a]pyridine as a New Player in the Field of IDO1 Catalytic Holo‐Inhibitors.

Published in:

ChemMedChem, 2021, v. 16, n. 22, p. 3439, doi. 10.1002/cmdc.202100446

By:

Fallarini, Silvia;
Bhela, Irene P.;
Aprile, Silvio;
Torre, Enza;
Ranza, Alice;
Orecchini, Elena;
Panfili, Eleonora;
Pallotta, Maria T.;
Massarotti, Alberto;
Serafini, Marta;
Pirali, Tracey

Publication type:

Article

Synthesis, Docking and Biological Evaluation of a Novel Class of Imidazothiazoles as IDO1 Inhibitors.

Published in:

Molecules, 2019, v. 24, n. 10, p. 1874, doi. 10.3390/molecules24101874

By:

Serafini, Marta;
Torre, Enza;
Aprile, Silvio;
Massarotti, Alberto;
Fallarini, Silvia;
Pirali, Tracey;
Kafarski, Pawel

Publication type:

Article

Identification of Novel Antitubulin Agents by Using a Virtual Screening Approach Based on a 7-Point Pharmacophore Model of the Tubulin Colchi-Site.

Published in:

Chemical Biology & Drug Design, 2011, v. 78, n. 6, p. 913, doi. 10.1111/j.1747-0285.2011.01245.x

By:

Massarotti, Alberto;
Theeramunkong, Sewan;
Mesenzani, Ornella;
Caldarelli, Antonio;
Genazzani, Armando A.;
Tron, Gian Cesare

Publication type:

Article