Works by Masato Akiyama

Results: 58
    1
    2
    3

    X-chromosome and kidney function: evidence from a multi-trait genetic analysis of 908,697 individuals reveals sex-specific and sex-differential findings in genes regulated by androgen response elements.

    Published in:
    Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-44709-1
    By:
    • Scholz, Markus;
    • Horn, Katrin;
    • Pott, Janne;
    • Wuttke, Matthias;
    • Kühnapfel, Andreas;
    • Nasr, M. Kamal;
    • Kirsten, Holger;
    • Li, Yong;
    • Hoppmann, Anselm;
    • Gorski, Mathias;
    • Ghasemi, Sahar;
    • Li, Man;
    • Tin, Adrienne;
    • Chai, Jin-Fang;
    • Cocca, Massimiliano;
    • Wang, Judy;
    • Nutile, Teresa;
    • Akiyama, Masato;
    • Åsvold, Bjørn Olav;
    • Bansal, Nisha
    Publication type:
    Article
    4
    5

    Genome-wide meta-analysis identifies multiple novel loci associated with serum uric acid levels in Japanese individuals.

    Published in:
    Communications Biology, 2019, v. 2, n. 1, p. N.PAG, doi. 10.1038/s42003-019-0339-0
    By:
    • Nakatochi, Masahiro;
    • Kanai, Masahiro;
    • Nakayama, Akiyoshi;
    • Hishida, Asahi;
    • Kawamura, Yusuke;
    • Ichihara, Sahoko;
    • Akiyama, Masato;
    • Ikezaki, Hiroaki;
    • Furusyo, Norihiro;
    • Shimizu, Seiko;
    • Yamamoto, Ken;
    • Hirata, Makoto;
    • Okada, Rieko;
    • Kawai, Sayo;
    • Kawaguchi, Makoto;
    • Nishida, Yuichiro;
    • Shimanoe, Chisato;
    • Ibusuki, Rie;
    • Takezaki, Toshiro;
    • Nakajima, Mayuko
    Publication type:
    Article
    6
    7
    8
    9

    Intraocular human cytomegaloviruses of ocular diseases are distinct from those of viremia and are capable of escaping from innate and adaptive immunity by exploiting HLA-E-mediated peripheral and central tolerance.

    Published in:
    Frontiers in Immunology, 2022, v. 13, p. 1, doi. 10.3389/fimmu.2022.1008220
    By:
    • Mariko Shirane;
    • Nobuyo Yawata;
    • Daisuke Motooka;
    • Kensuke Shibata;
    • Seik-Soon Khor;
    • Yosuke Omae;
    • Toshikatsu Kaburaki;
    • Ryoji Yanai;
    • Hisashi Mashimo;
    • Satoshi Yamana;
    • Takako Ito;
    • Akira Hayashida;
    • Yasuo Mori;
    • Akihiko Numata;
    • Yusuke Murakami;
    • Kohta Fujiwara;
    • Nobuyuki Ohguro;
    • Mayumi Hosogai;
    • Masato Akiyama;
    • Eiichi Hasegawa
    Publication type:
    Article
    10

    Elucidating the genetic architecture of reproductive ageing in the Japanese population.

    Published in:
    Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-04398-z
    By:
    • Momoko Horikoshi;
    • Day, Felix R.;
    • Masato Akiyama;
    • Makoto Hirata;
    • Yoichiro Kamatani;
    • Koichi Matsuda;
    • Kazuyoshi Ishigaki;
    • Masahiro Kanai;
    • Wright, Hollis;
    • Toro, Carlos A.;
    • Ojeda, Sergio R.;
    • Lomniczi, Alejandro;
    • Kubo, Michiaki;
    • Ong, Ken K.;
    • Perry, John R. B.
    Publication type:
    Article
    11
    12
    13

    Population-specific reference panel improves imputation quality for genome-wide association studies conducted on the Japanese population.

    Published in:
    Communications Biology, 2024, v. 7, n. 1, p. 1, doi. 10.1038/s42003-024-07338-4
    By:
    • Flanagan, Jack;
    • Liu, Xiaoxi;
    • Ortega-Reyes, David;
    • Tomizuka, Kohei;
    • Matoba, Nana;
    • Akiyama, Masato;
    • Koido, Masaru;
    • Ishigaki, Kazuyoshi;
    • Ashikawa, Kyota;
    • Takata, Sadaaki;
    • Shi, MingYang;
    • Aoi, Tomomi;
    • Momozawa, Yukihide;
    • Ito, Kaoru;
    • Murakami, Yoshinori;
    • Matsuda, Koichi;
    • The Biobank Japan Project;
    • Yamanashi, Yuji;
    • Furukawa, Yoichi;
    • Morisaki, Takayuki
    Publication type:
    Article
    14

    Association of Birth Weight With Type 2 Diabetes and Glycemic Traits: A Mendelian Randomization Study.

    Published in:
    JAMA Network Open, 2019, v. 29, p. e1910915, doi. 10.1001/jamanetworkopen.2019.10915
    By:
    • Huang, Tao;
    • Wang, Tiange;
    • Zheng, Yan;
    • Ellervik, Christina;
    • Li, Xiang;
    • Gao, Meng;
    • Fang, Zhe;
    • Chai, Jin-Fang;
    • Ahluwalia, Tarun veer S.;
    • Wang, Yujie;
    • Voortman, Trudy;
    • Noordam, Raymond;
    • Frazier-Wood, Alexis;
    • Scholz, Markus;
    • Sonestedt, Emily;
    • Akiyama, Masato;
    • Dorajoo, Rajkumar;
    • Zhou, Ang;
    • Kilpeläinen, Tuomas O.;
    • Kleber, Marcus E.
    Publication type:
    Article
    15
    16
    17
    18
    19

    Regional differences in genes and variants causing retinitis pigmentosa in Japan.

    Published in:
    Japanese Journal of Ophthalmology, 2021, v. 65, n. 3, p. 338, doi. 10.1007/s10384-021-00824-w
    By:
    • Koyanagi, Yoshito;
    • Akiyama, Masato;
    • Nishiguchi, Koji M;
    • Momozawa, Yukihide;
    • Kamatani, Yoichiro;
    • Takata, Sadaaki;
    • Inai, Chihiro;
    • Iwasaki, Yusuke;
    • Kumano, Mikako;
    • Murakami, Yusuke;
    • Komori, Shiori;
    • Gao, Dan;
    • Kurata, Kentaro;
    • Hosono, Katsuhiro;
    • Ueno, Shinji;
    • Hotta, Yoshihiro;
    • Murakami, Akira;
    • Terasaki, Hiroko;
    • Wada, Yuko;
    • Nakazawa, Toru
    Publication type:
    Article
    20
    21

    TNFRSF10A downregulation induces retinal pigment epithelium degeneration during the pathogenesis of age-related macular degeneration and central serous chorioretinopathy.

    Published in:
    Human Molecular Genetics, 2022, v. 31, n. 13, p. 2194, doi. 10.1093/hmg/ddac020
    By:
    • Mori, Kenichiro;
    • Ishikawa, Keijiro;
    • Fukuda, Yosuke;
    • Ji, Rui;
    • Wada, Iori;
    • Kubo, Yuki;
    • Akiyama, Masato;
    • Notomi, Shoji;
    • Murakami, Yusuke;
    • Nakao, Shintaro;
    • Arakawa, Satoshi;
    • Shiose, Satomi;
    • Hisatomi, Toshio;
    • Yoshida, Shigeo;
    • Kannan, Ram;
    • Sonoda, Koh-Hei
    Publication type:
    Article
    22
    23

    Genome-wide association study identifies seven novel susceptibility loci for primary open-angle glaucoma.

    Published in:
    Human Molecular Genetics, 2018, v. 27, n. 8, p. 1486, doi. 10.1093/hmg/ddy053
    By:
    • Yukihiro Shiga;
    • Masato Akiyama;
    • Nishiguchi, Koji M.;
    • Kota Sato;
    • Nobuhiro Shimozawa;
    • Atsushi Takahashi;
    • Yukihide Momozawa;
    • Makoto Hirata;
    • Koichi Matsuda;
    • Taiki Yamaji;
    • Motoki Iwasaki;
    • Shoichiro Tsugane;
    • Isao Oze;
    • Haruo Mikami;
    • Mariko Naito;
    • Kenji Wakai;
    • Munemitsu Yoshikawa;
    • Masahiro Miyake;
    • Kenji Yamashiro;
    • Kenji Kashiwagi
    Publication type:
    Article
    24
    25
    26

    Characterizing rare and low-frequency height-associated variants in the Japanese population.

    Published in:
    Nature Communications, 2019, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41467-019-12276-5
    By:
    • Akiyama, Masato;
    • Ishigaki, Kazuyoshi;
    • Sakaue, Saori;
    • Momozawa, Yukihide;
    • Horikoshi, Momoko;
    • Hirata, Makoto;
    • Matsuda, Koichi;
    • Ikegawa, Shiro;
    • Takahashi, Atsushi;
    • Kanai, Masahiro;
    • Suzuki, Sadao;
    • Matsui, Daisuke;
    • Naito, Mariko;
    • Yamaji, Taiki;
    • Iwasaki, Motoki;
    • Sawada, Norie;
    • Tanno, Kozo;
    • Sasaki, Makoto;
    • Hozawa, Atsushi;
    • Minegishi, Naoko
    Publication type:
    Article
    27

    A frequent variant in the Japanese population determines quasi-Mendelian inheritance of rare retinal ciliopathy.

    Published in:
    Nature Communications, 2019, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41467-019-10746-4
    By:
    • Nikopoulos, Konstantinos;
    • Cisarova, Katarina;
    • Quinodoz, Mathieu;
    • Koskiniemi-Kuendig, Hanna;
    • Miyake, Noriko;
    • Farinelli, Pietro;
    • Rehman, Atta Ur;
    • Khan, Muhammad Imran;
    • Prunotto, Andrea;
    • Akiyama, Masato;
    • Kamatani, Yoichiro;
    • Terao, Chikashi;
    • Miya, Fuyuki;
    • Ikeda, Yasuhiro;
    • Ueno, Shinji;
    • Fuse, Nobuo;
    • Murakami, Akira;
    • Wada, Yuko;
    • Terasaki, Hiroko;
    • Sonoda, Koh-Hei
    Publication type:
    Article
    28

    Interethnic analyses of blood pressure loci in populations of East Asian and European descent.

    Published in:
    Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-07345-0
    By:
    • Takeuchi, Fumihiko;
    • Akiyama, Masato;
    • Matoba, Nana;
    • Katsuya, Tomohiro;
    • Nakatochi, Masahiro;
    • Tabara, Yasuharu;
    • Narita, Akira;
    • Saw, Woei-Yuh;
    • Moon, Sanghoon;
    • Spracklen, Cassandra N.;
    • Chai, Jin-Fang;
    • Kim, Young-Jin;
    • Zhang, Liang;
    • Wang, Chaolong;
    • Li, Huaixing;
    • Li, Honglan;
    • Wu, Jer-Yuarn;
    • Dorajoo, Rajkumar;
    • Nierenberg, Jovia L.;
    • Wang, Ya Xing
    Publication type:
    Article
    29

    Genome-wide analyses identify a role for SLC17A4 and AADAT in thyroid hormone regulation.

    Published in:
    Nature Communications, 2018, v. 9, p. 1, doi. 10.1038/s41467-018-06356-1
    By:
    • Teumer, Alexander;
    • Chaker, Layal;
    • Groeneweg, Stefan;
    • Li, Yong;
    • Di Munno, Celia;
    • Barbieri, Caterina;
    • Schultheiss, Ulla T.;
    • Traglia, Michela;
    • Ahluwalia, Tarunveer S.;
    • Akiyama, Masato;
    • Appel, Emil Vincent R.;
    • Arking, Dan E.;
    • Arnold, Alice;
    • Astrup, Arne;
    • Beekman, Marian;
    • Beilby, John P.;
    • Bekaert, Sofie;
    • Boerwinkle, Eric;
    • Brown, Suzanne J.;
    • De Buyzere, Marc
    Publication type:
    Article
    30
    31
    32

    Genome-Wide Association Study of Renal Function Traits: Results from the Japan Multi-Institutional Collaborative Cohort Study.

    Published in:
    2018
    By:
    • Hishida, Asahi;
    • Nakatochi, Masahiro;
    • Akiyama, Masato;
    • Kamatani, Yoichiro;
    • Nishiyama, Takeshi;
    • Ito, Hidemi;
    • Oze, Isao;
    • Nishida, Yuichiro;
    • Hara, Megumi;
    • Takashima, Naoyuki;
    • Turin, Tanvir Chowdhury;
    • Watanabe, Miki;
    • Suzuki, Sadao;
    • Ibusuki, Rie;
    • Shimoshikiryo, Ippei;
    • Nakamura, Yohko;
    • Mikami, Haruo;
    • Ikezaki, Hiroaki;
    • Furusyo, Norihiro;
    • Kuriki, Kiyonori
    Publication type:
    journal article
    33

    Genome-wide association study reveals BET1L associated with survival time in the 137,693 Japanese individuals.

    Published in:
    Communications Biology, 2023, v. 6, n. 1, p. 1, doi. 10.1038/s42003-023-04491-0
    By:
    • Akiyama, Masato;
    • Sakaue, Saori;
    • Takahashi, Atsushi;
    • Ishigaki, Kazuyoshi;
    • Hirata, Makoto;
    • Matsuda, Koichi;
    • Momozawa, Yukihide;
    • Okada, Yukinori;
    • Ninomiya, Toshiharu;
    • The Biobank Japan project;
    • Koido, Masaru;
    • Morisaki, Takayuki;
    • Nagai, Akiko;
    • Sagiya, Yoji;
    • Terao, Chikashi;
    • Murakami, Yoshinori;
    • Kubo, Michiaki;
    • Kamatani, Yoichiro
    Publication type:
    Article
    34
    35

    Integration of genetics and miRNA–target gene network identified disease biology implicated in tissue specificity.

    Published in:
    Nucleic Acids Research, 2018, v. 46, n. 22, p. 11898, doi. 10.1093/nar/gky1066
    By:
    • Sakaue, Saori;
    • Hirata, Jun;
    • Maeda, Yuichi;
    • Kawakami, Eiryo;
    • Nii, Takuro;
    • Kishikawa, Toshihiro;
    • Ishigaki, Kazuyoshi;
    • Terao, Chikashi;
    • Suzuki, Ken;
    • Akiyama, Masato;
    • Suita, Naomasa;
    • Masuda, Tatsuo;
    • Ogawa, Kotaro;
    • Yamamoto, Kenichi;
    • Saeki, Yukihiko;
    • Matsushita, Masato;
    • Yoshimura, Maiko;
    • Matsuoka, Hidetoshi;
    • Ikari, Katsunori;
    • Taniguchi, Atsuo
    Publication type:
    Article
    36
    37

    A hypomorphic variant in EYS detected by genome-wide association study contributes toward retinitis pigmentosa.

    Published in:
    Communications Biology, 2021, v. 4, n. 1, p. 1, doi. 10.1038/s42003-021-01662-9
    By:
    • Nishiguchi, Koji M.;
    • Miya, Fuyuki;
    • Mori, Yuka;
    • Fujita, Kosuke;
    • Akiyama, Masato;
    • Kamatani, Takashi;
    • Koyanagi, Yoshito;
    • Sato, Kota;
    • Takigawa, Toru;
    • Ueno, Shinji;
    • Tsugita, Misato;
    • Kunikata, Hiroshi;
    • Cisarova, Katarina;
    • Nishino, Jo;
    • Murakami, Akira;
    • Abe, Toshiaki;
    • Momozawa, Yukihide;
    • Terasaki, Hiroko;
    • Wada, Yuko;
    • Sonoda, Koh-Hei
    Publication type:
    Article
    38
    39

    Cohort Profile: The Ganka-Ekigaku Network (GEN), a Network of Japanese Ophthalmological Epidemiology Studies.

    Published in:
    Ophthalmic Epidemiology, 2021, v. 28, n. 3, p. 237, doi. 10.1080/09286586.2020.1815803
    By:
    • Sasaki, Mariko;
    • Miyake, Masahiro;
    • Fujiwara, Kohta;
    • Nanba, Hiroyuki;
    • Akiyama, Masato;
    • Yanagi, Yasuo;
    • Harada, Sei;
    • Tabara, Yasuharu;
    • Yasuda, Miho;
    • Yamashita, Hidetoshi;
    • Kayama, Takamasa;
    • Tsubota, Kazuo;
    • Matsuda, Fumihiko;
    • Hashimoto, Sawako;
    • Ueda, Emi;
    • Ninomiya, Toshiharu;
    • Takebayashi, Toru;
    • Tsujikawa, Akitaka;
    • Sonoda, Koh-Hei;
    • Kawasaki, Ryo
    Publication type:
    Article
    40

    Low-frequency coding variants in CETP and CFB are associated with susceptibility of exudative age-related macular degeneration in the Japanese population.

    Published in:
    Human Molecular Genetics, 2016, v. 25, n. 22, p. 5027, doi. 10.1093/hmg/ddw335
    By:
    • Yukihide Momozawa;
    • Masato Akiyama;
    • Yoichiro Kamatani;
    • Satoshi Arakawa;
    • Miho Yasuda;
    • Shigeo Yoshida;
    • Yuji Oshima;
    • Ryusaburo Mori;
    • Koji Tanaka;
    • Keisuke Mori;
    • Satoshi Inoue;
    • Hiroko Terasaki;
    • Tetsuhiro Yasuma;
    • Shigeru Honda;
    • Akiko Miki;
    • Maiko Inoue;
    • Kimihiko Fujisawa;
    • Kanji Takahashi;
    • Tsutomu Yasukawa;
    • Yasuo Yanagi
    Publication type:
    Article
    41

    Dimensionality reduction reveals fine-scale structure in the Japanese population with consequences for polygenic risk prediction.

    Published in:
    Nature Communications, 2020, v. 11, n. 1, p. 1, doi. 10.1038/s41467-020-15194-z
    By:
    • Sakaue, Saori;
    • Hirata, Jun;
    • Kanai, Masahiro;
    • Suzuki, Ken;
    • Akiyama, Masato;
    • Lai Too, Chun;
    • Arayssi, Thurayya;
    • Hammoudeh, Mohammed;
    • Al Emadi, Samar;
    • Masri, Basel K.;
    • Halabi, Hussein;
    • Badsha, Humeira;
    • Uthman, Imad W.;
    • Saxena, Richa;
    • Padyukov, Leonid;
    • Hirata, Makoto;
    • Matsuda, Koichi;
    • Murakami, Yoshinori;
    • Kamatani, Yoichiro;
    • Okada, Yukinori
    Publication type:
    Article
    42
    43

    Study design and baseline characteristics of a population-based prospective cohort study of dementia in Japan: the Japan Prospective Studies Collaboration for Aging and Dementia (JPSC-AD).

    Published in:
    Environmental Health & Preventive Medicine, 2020, v. 25, n. 1, p. N.PAG, doi. 10.1186/s12199-020-00903-3
    By:
    • Ninomiya, Toshiharu;
    • Nakaji, Shigeyuki;
    • Maeda, Tetsuya;
    • Yamada, Masahito;
    • Mimura, Masaru;
    • Nakashima, Kenji;
    • Mori, Takaaki;
    • Takebayashi, Minoru;
    • Ohara, Tomoyuki;
    • Hata, Jun;
    • Kokubo, Yoshihiro;
    • Uchida, Kazuhiro;
    • Taki, Yasuyuki;
    • Kumagai, Shuzo;
    • Yonemoto, Koji;
    • Yoshida, Hisako;
    • Muto, Kaori;
    • Momozawa, Yukihide;
    • Akiyama, Masato;
    • Kubo, Michiaki
    Publication type:
    Article
    44

    Genetic variants associated with glaucomatous visual field loss in primary open-angle glaucoma.

    Published in:
    Scientific Reports, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41598-022-24915-x
    By:
    • Mabuchi, Fumihiko;
    • Mabuchi, Nakako;
    • Sakurada, Yoichi;
    • Yoneyama, Seigo;
    • Kashiwagi, Kenji;
    • Yamagata, Zentaro;
    • Takamoto, Mitsuko;
    • Aihara, Makoto;
    • Iwata, Takeshi;
    • Hashimoto, Kazuki;
    • Sato, Kota;
    • Shiga, Yukihiro;
    • Nakazawa, Toru;
    • Akiyama, Masato;
    • Kawase, Kazuhide;
    • Ozaki, Mineo;
    • Araie, Makoto
    Publication type:
    Article
    45

    Discerning asthma endotypes through comorbidity mapping.

    Published in:
    Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-33628-8
    By:
    • Jia, Gengjie;
    • Zhong, Xue;
    • Im, Hae Kyung;
    • Schoettler, Nathan;
    • Pividori, Milton;
    • Hogarth, D. Kyle;
    • Sperling, Anne I.;
    • White, Steven R.;
    • Naureckas, Edward T.;
    • Lyttle, Christopher S.;
    • Terao, Chikashi;
    • Kamatani, Yoichiro;
    • Akiyama, Masato;
    • Matsuda, Koichi;
    • Kubo, Michiaki;
    • Cox, Nancy J.;
    • Ober, Carole;
    • Rzhetsky, Andrey;
    • Solway, Julian
    Publication type:
    Article
    46

    Discerning asthma endotypes through comorbidity mapping.

    Published in:
    Nature Communications, 2022, v. 13, p. 1, doi. 10.1038/s41467-022-33628-8
    By:
    • Jia, Gengjie;
    • Zhong, Xue;
    • Im, Hae Kyung;
    • Schoettler, Nathan;
    • Pividori, Milton;
    • Hogarth, D. Kyle;
    • Sperling, Anne I.;
    • White, Steven R.;
    • Naureckas, Edward T.;
    • Lyttle, Christopher S.;
    • Terao, Chikashi;
    • Kamatani, Yoichiro;
    • Akiyama, Masato;
    • Matsuda, Koichi;
    • Kubo, Michiaki;
    • Cox, Nancy J.;
    • Ober, Carole;
    • Rzhetsky, Andrey;
    • Solway, Julian
    Publication type:
    Article
    47
    48
    49
    50